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Pengaruh Kolaborasi Gizi Dan Farmasi terhadap Tingkat Pengetahuan Diabetes Mellitus Lansia Ratna Wijayatri; Yulinda Kurniasari; Lulu Fathnatul Ulya; Emelda Emelda
INPHARNMED Journal (Indonesian Pharmacy and Natural Medicine Journal) Vol. 5 No. 2 (2021)
Publisher : Alma Ata University Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21927/inpharnmed.v5i2.1924

Abstract

Diabetes Melitus (DM) merupakan penyakit menahun dan kronis yang pengobatannya memerlukan waktu yang lama. Penyakit DM memberikan dampak yang buruk untuk kesehatan karena adanya komplikasi yang serius baik mikrovaskuler maupun makrovaskuler.  Hampir 50% kasus DM dialami oleh pasien dengan usia 65 tahun keatas. DM pada usia lanjut berbeda secara metabolik dengan DM pada usia lainnya sehingga dibutuhkan pendekatan terapi yang berbeda pada kelompok ini. Hal ini dikarenakan pada usia lanjut telah mengalami kemunduran fisik dan mental yang berakibat pada penurunan kualitas hidup dan penurunan pemahaman dalam memahami perintah menggunakan obat. Metode CBIA (Community Based Intensive Aproach) yang bersinergi antara Gizi dan Farmasi diterapkan dalam peningkatan pengetahuan terhadap kadar gula darah dan pengontrolannya pada pasien usia lanjut yang menderita DM. Penelitian ini merupakan penelitian kuantitatif pre post test design, dengan kontrol design. Responden diambil dari 2 puskesmas di Bantul dengan metode purposive sampling, dan diperoleh 60 responden lansia yang masuk ke dalam kriteria inklusi.Hasil pengukuran tingkat pengetahuan setelah dilakukan intervensi berupa asuhan farmasi dan gizi yang bersama-sama dengan metode CBIA mengalami peningkatan dibandingkan kelompok kontrol. Tingkat pengetahuan responden sebelum diberikan intervensi terdapat 4 responden dengan pengetahuan rendah, 26 responden dengan pengetahuan sedang, 30 responden dengan pengetahuan tinggi. Mengalami peningkatan pengetahuan menjadi terdapat 58 dengan pengetahuan tinggi, dan 2 rendah. Hal ini menunjukkan adanya pengaruh pemberian intervensi CBIA yang bersinergi antara gizi dan farmasi dalam meningkatkan pengetahuan pasien lansia terhadap DM.
A Case Study: Application of Kersen Leaf Extract (Muntingia Calabura L.) and Manuka Honey Ointment Combination On Second Degree Superficial Burns Shella Oktavia Cahyaningrum; Estrin Handayani; Eka Sakti Wahyuningtyas; Ratna Wijayatri
Viva Medika Vol 17 No 1 (2024)
Publisher : LPPM Universitas Harapan Bangsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35960/vm.v17i1.1302

Abstract

Background: Burns are a significant cause of morbidity and mortality globally. Intensive treatment is necessary to prevent infection and manage erythema in burn wounds. This case study aims to evaluate the effectiveness of a combination ointment containing Kersen (Muntingia calabura L.) leaf extract and Manuka honey in treating second degree superficial burns. Methods: A case study design employing evidence-based practice was used. Data were collected through interviews, observations, and physical examination. The study was conducted from October 14-28, 2023 in Mirikerep Hamlet, Pringsurat Village, Temanggung Regency, Indonesia. A comprehensive nursing care approach was implemented, including assessment, diagnosis, intervention, implementation, and evaluation. Results: Macroscopic examination revealed a significant reduction in wound area from 5.5x3 cm to 0.5x0.3 cm after treatment with the combination ointment. The ointment effectively promoted epithelialization and tissue regeneration in the healing process of second-degree superficial burns. Conclusions: The combination ointment containing Kersen leaf extract and Manuka honey demonstrates potential as an effective treatment for second degree superficial burns. Further research is warranted to elucidate the mechanisms underlying its therapeutic effects.
Identifikasi Senyawa Aktif dalam Daun Dadap Serep (Erythrina subumbrans (Hassk.) Merr) dan Potensinya sebagai Antioksidan Lailatul Azizah Okta Nauval; Ratna Wijayatri; Tiwi Oktaviyani
Journal of Pharmaceutical and Sciences JPS Volume 9 Nomor 1 (2026)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v9i1.1164

Abstract

Background: Erythrina subumbrans (Hassk.) Merr, locally known as dadap serep, is a medicinal plant traditionally used to treat various ailments, suggesting the presence of bioactive compounds. Scientific exploration of its phytochemical profile and antioxidant potential, however, remains limited compared to other species in the genus. Objective: This study aimed to (1) identify the bioactive compound groups in the 70% ethanol extract of Erythrina subumbrans leaves through phytochemical screening and Thin Layer Chromatography (TLC), and (2) evaluate its antioxidant activity quantitatively using the DPPH (2,2-diphenyl-1-picrylhydrazyl) radical scavenging method. Methods: The leaves were extracted via maceration using 70% ethanol. The extract was subjected to standard phytochemical screening tests for flavonoids, alkaloids, saponins, and tannins. Flavonoid profiling was performed using TLC with a quercetin standard. Antioxidant activity was assessed by the DPPH method, with vitamin C as a reference standard, and the IC₅₀ value was determined. Results: Phytochemical screening confirmed the presence of flavonoids, alkaloids, saponins, and tannins. TLC analysis indicated the presence of flavonoid compounds, with one major spot showing an Rf value similar to the quercetin standard. The DPPH assay revealed that the extract possesses strong antioxidant activity, with an IC₅₀ value of 49.94 ppm. According to established antioxidant strength criteria, this IC₅₀ value is categorized as very strong.Conclusion: The 70% ethanol extract of Erythrina subumbrans leaves contains diverse bioactive compounds, particularly flavonoids, and exhibits very strong antioxidant activity. These findings scientifically support its traditional use and highlight its potential as a promising source of natural antioxidants for further pharmaceutical or nutraceutical development.