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All Journal INSPIRASI Biocelebes Medika Tadulako Public Health of Indonesia Poltekita : Jurnal Ilmu Kesehatan Indonesian Journal of Clinical Pathology and Medical Laboratory (IJCPML) SCRIPTA SCORE Scientific Medical Journal International Journal of Health, Economics, and Social Sciences (IJHESS) Healthy Tadulako Journal (Jurnal Kesehatan Tadulako) Jurnal Bidan Cerdas Medika Tadulako: Jurnal Ilmiah Kedokteran Fakultas Kedokteran
Rosa Dwi Wahyuni
Fakultas Kedokteran Universitas Tadulako, Palu, Indonesia
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Dentistry Economics, Econometrics & Finance Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Other

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Laporan Kasus: Pemeriksaan Tes PCR untuk SARS-CoV-2 Tetap Positif dengan Gejala Klinis Minimal di RSUD.Undata Palu, Sulawesi Tengah Indah Fitriyani; Rosa Dwi Wahyuni; Reny Arniwaty Lamadjido
SCRIPTA SCORE Scientific Medical Journal Vol. 3 No. 1 (2021): SCRIPTA SCORE Scientific Medical Journal
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/scripta.v3i1.6363

Abstract

Background: Coronavirus Disease 2019 (COVID-19) is an infectious disease caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). SARS-CoV-2 is a new type of corona virus that has never been previously identified in humans. There are at least two types of coronavirus that are known to cause diseases that can cause severe symptoms, such as Middle East Respiratory Syndrome (MERS) and Severe Acute Respiratory Syndrome (SARS). WHO recommends molecular testing for all patients suspected of being infected with COVID-19. The recommended method is the molecular detection method / NAAT (Nucleic Acid Amplification Test) such as the RT-PCR examination. Objectives: To report a case of Covid 19 which focuses on laboratory examination problems. Case Illustration: A 27-year-old woman has a persistent high fever accompanied by pain in the joints, coughing, and also a rash on the face and all over the body. On the fourth day of fever, the sufferer loses his sense of smell and taste. Work history as a volunteer for medical personnel in the Covid (+) room. Discussion: Laboratory tests for the diagnosis of Covid 19 consist of a complete hematology examination, clinical chemical examination, immunological examination, molecular examination (RT-PCR), examination of SARS CoV-2 antibodies. Conclusion: In this patient, the results of the swab were still reactive even though the patient was no longer showing clinical symptoms. This indicates that the virus can still be detected through RT-PCR examination. Keywords: clinical symptoms, Covid 19 PCR test, SARS-CoV-2   Latar Belakang: Coronavirus Disease 2019 (COVID-19) adalah penyakit menular yang disebabkan oleh Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). SARS-CoV-2 merupakan corona virus jenis baru yang belum pernah diidentifikasi sebelumnya pada manusia. Ada setidaknya dua jenis corona virus yang diketahui menyebabkan penyakit yang dapat menimbulkan gejala berat seperti Middle East Respiratory Syndrome (MERS) dan Severe Acute Respiratory Syndrome (SARS). WHO  merekomendasikan  pemeriksaan molekuler untuk seluruh pasien yang terduga terinfeksi COVID-19. Metode yang dianjurkan adalah  metode deteksi molekuler/NAAT (Nucleic Acid Amplification Test) seperti pemeriksaan RT-PCR. Tujuan: Melaporkan satu kasus Covid 19 yang menitikberatkan pada masalah pemeriksaan laboratorium. Ilustrasi Kasus: Seorang wanita usia 27 tahun  mengalami demam tinggi terus menerus disertai nyeri pada persendian, batuk, dan juga timbul ruam di wajah dan seluruh badan. Hari ke empat demam, penderita mengalami kehilangan indra penciuman dan indra perasa. Riwayat kerja sebagai sukarela tenaga medis di ruangan Covid (+).  Pembahasan: Pemeriksaan laboratorium untuk diagnosis Covid 19  terdiri dari pemeriksaan hematologi lengkap, pemeriksaan kimia klinik, pemeriksaan immunologi, pemeriksaan molekular (RT-PCR), pemeriksaan antibody SARS CoV-2. Kesimpulan: Pada pasien ini didapatkan hasil swab yang masih terus reaktif walaupun pasien sudah tidak lagi menunjukkan gejala klinis. Ini mengindikasikan bahwa virus masih dapat terdeteksi melalui pemeriksaan RT-PCR. Kata Kunci: gejala klinis, pemeriksaan PCR Covid 19, SARS-CoV-2
Understanding Rural Perspectives and Practices of Health in Banggai Laut, Indonesia M. Sabir; Muh. Ardi Munir; Tri Setyawati; Muhammad Nasir; Ary Anggara; Ressy Dwiyanti; Rosa Dwi Wahyuni; Rahma; Vera Diana Towidjojo; Sarifuddin; Aristo; Mochammad Hatta
International Journal of Health, Economics, and Social Sciences (IJHESS) Vol. 5 No. 3: July 2023
Publisher : Universitas Muhammadiyah Palu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56338/ijhess.v5i3.3734

Abstract

Health is always an important value for human beings and the most fundamental condition of life. Health is perceived differently influenced by many factors including education, experience, knowledge, culture, and environment. The study aimed to explore community perception of health, including causes of diseases, and choices of help for health problems in rural setting in Central Sulawesi, Indonesia. The study is a qualitative ethnography with several data collection methods including semi structured in-depth interviews, small group discussion, informal conversations, photography, and direct observation. Study location was in Bangkurung sub-district. The study found that health is perceived as a power, energy, normal physiology of human body, and ability to work normally. Participants understood and believed that health is influenced by many factors including environment, food, lifestyle, social interaction and the rise of megycism, traditionally prohibited behaviors, religious belief, mind, and workload. Community members commonly used both medical treatment and traditional healing methods.
EPIDEMIOLOGICAL MODEL OF STUNTING DETERMINANTS IN INDONESIA Adhar Arifuddin; Yuli Prihatni; Ari Setiawan; Rosa Dwi Wahyuni; A Fahira Nur; Nur Eka Dyastuti; Hidayanti Arifuddin
Healthy Tadulako Journal (Jurnal Kesehatan Tadulako) Vol. 9 No. 2 (2023)
Publisher : Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/htj.v9i2.928

Abstract

Stunting dapat menghambat pertumbuhan fisik, meningkatkan kerentanan anak terhadap penyakit, hambatan perkembangan kognitif yang menurunkan kecerdasan dan produktivitas anak di masa depan. Penelitian ini bertujuan menggali fenomena determinan stunting pada anak dengan pendekatan epidemiologi. Jenis penelitian kualitatif dengan pendekatan fenomenologi. Partisipan dalam penelitian ini adalah para ibu yang memiliki anak menderita stunting sebanyak 8 informan di Sulawesi Tengah. Partisipan berusia antara 25 sampai dengan 35 tahun yang berdomisili di daerah perkotaan dan pedesaan. Pengumpulan data menggunakan angket yang dilengkapi wawancara. Penggunaan angket untuk mengeksplorasi faktor risiko dan mengidentifikasi berbagai determinan stunting dengan pendekatan trias epidemiologi. Hasil penelitian ini menunjukkan bahwa determinan stunting dengan pendekatan trias epidemiologi diantaranya faktor host terdiri dari penyakit infeksi yang diderita, kurang asupan gizi/ status gizi, ketahanan pangan yang rendah, pola asuh/pola makan yang buruk, kualitas dan kuantitas makanan yang rendah, ASI eksklusif, serta gangguan mental dan hipertensi pada ibu. Faktor agent terdiri dari bakteri, parasit dan virus yang mengakibatkan diare, ISPA dan campak pada anak. Faktor environment terdiri dari sanitasi, akses air bersih, bahan bakar memasak, perilaku merokok, dan paparan asap rokok. Pengembangan riset literature review diperlukan dalam menentukan faktor lain sebagai determinan stunting pada anak untuk mengembangkan riset epidemiologi dalam mengendalikan faktor risiko stunting.
Potential Toxicity of The Combination of Hydroxychloroquine and Azithromycin for Covid-19 Therapy: Literature Review M. Sabir Mangawing; Rosa Dwi Wahyuni
Poltekita : Jurnal Ilmu Kesehatan Vol. 17 No. 2 (2023): August
Publisher : Poltekkes Kemenkes Palu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33860/jik.v17i2.2890

Abstract

One of the therapies often used for COVID-19 patients is a combination of Hydroxychloroquine and Azithromycin. Although only short-term treatment, Hydroxychloroquine and Azithromycin may increase the risks of QTc and TdP intervals prolongation. This literature review aims to determine the potential toxicity of the combination of Hydroxychloroquine and Azithromycin for COVID-19 therapy. This study involved the PubMed, NCBI, Science Direct, NIH MEDLINE, Google Scholar and ProQuest databases. The 24 articles collected were then selected. Finally, 15 articles were found feasible for references in a literature review. The study results showed that combined Hydroxychloroquine and Azithromycin in COVID-19 therapy could increase the risk of QTc and TdP waves prolongation. It can be concluded that the combination of Hydroxychloroquine and Azithromycin carried the risk of prolongation of QTc and TdP waves in the heart rhythm cycle. There is a need for monitoring and/or recommendation regarding instructions for the use of combination therapy of the two types of drugs among patients with COVID-19.
Quality and Pattern of Breakfast Through the GEMPITA PROGRAM at Palu City, Central Sulawesi Darma Ariany; Adhyanti Adhyanti; Yayuk Eka Cahyani; Fahmi Hafid; Rosa Dwi Wahyuni; Dachruddin Ngatimin
Poltekita : Jurnal Ilmu Kesehatan Vol. 17 No. 3 (2023): November
Publisher : Poltekkes Kemenkes Palu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33860/jik.v17i3.3435

Abstract

Many school-aged children in Indonesia still skip breakfast, which can have an impact on their learning concentration and academic performance at school. This study aims to describe the quality and pattern of breakfast through the GEMPITA Program at Palu City, Central Sulawesi. This was a descriptive study with a sample size of 228 elementary and junior high school students in Palu City. Data collection was performed through interviews using structured questionnaires and anthropometric measurements. The study results show that the majority of respondents had pocket money of more than IDR 5,000/day, came from families with fathers of senior high school graduates and non-civil servants, the mothers generally had primary and secondary education and were housewives. Furthermore, the majority of respondents had a routine breakfast habit by 57.9%, 20.2% had breakfast sometimes and 21.9% never had breakfast. Furthermore, only 32.9% had quality breakfast menu. Regarding snack consumption habit, the majority of respondents by 77.2% consumed snacks more than three times a week and more than half of respondents by 58.3% had the habit of bringing packed meal, while 41.7% never brought packed meal. An assessment of the nutritional status of respondents showed that there were still 33.3% who were undernourished and 7.9% who were over nourished and obese. Stunting status occurred in 18.9% of respondents. The breakfast habit, quality and pattern of elementary and high school students still need to be improved. The GEMPITA program is an alternative program to improve the pattern and quality of breakfast for elementary and high school-aged children in Palu City.
The village government’s communication model: A promotion strategy for stunting prevention in Indonesia Nur, A Fahira; Suriati; Nur, Makmur Jaya; Arifuddin, Adhar; Rahman, Nurdin; Fajriah, Rasyika Nurul; Wahyuni, Rosa Dwi
Public Health of Indonesia Vol. 9 No. 4 (2023): October - December
Publisher : YCAB Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36685/phi.v9i4.719

Abstract

Background: Stunting remains a significant social issue among the population in Indonesia. Inadequate treatment has led to numerous cases of suboptimal height in children aged 19 years. Objective: This study aimed to explore the strategy of the village government in formulating communication messages, utilizing communication methods, and employing communication media for the stunting alleviation program. Methods: A phenomenological approach was employed, with the research conducted in Pulau Harapan Village, Nine Island District, Sinjai Regency. Data were gathered from the government officials of Pulau Harapan Village through observations, interviews, and documentation. Subsequently, the collected data underwent analysis involving reduction, presentation, verification, and conclusions drawing, facilitated by Atlas TI 8 software. Results: The village government's strategy in crafting stunting alleviation program messages, from socialization to implementation in Harapan Island Village, Nine Island District, Sinjai Regency, revolves around the Two-Step Flow Communication model. The communication methods used include information repetition, channelization, persuasion to alter the target mothers' perceptions, educational methods, and coercion (coerfindings). Media employed include print media, electronic media, and human resource mobilization within Harapan Island Village. Conclusion: The findings of the study provide valuable insights to address the stunting issue in Indonesia.
ANALISIS REGRESI LINIER BERGANDA DALAM ESTIMASI FAKTOR YANG MEMPENGARUHI CASE FATALITY RATE COVID-19 DI INDONESIA Arifuddin, Adhar; Arifuddin, Hidayanti; Arifuddin, Hikmayanti; Nur, A Fahira; Dyastuti, Nur Eka; Wahyuni, Rosa Dwi
Healthy Tadulako Journal (Jurnal Kesehatan Tadulako) Vol. 9 No. 1 (2023)
Publisher : Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/htj.v9i1.983

Abstract

Case Fatality Rate (CFR) merupakan salah satu pengukuran untuk melihat tingkat keparahan, risiko suatu penyakit pada populasi dan dapat digunakan untuk mengevaluasi mutu fasilitas pelayanan kesehatan. Data kematian akibat COVID-19 di Indonesia mencapai 9.837 orang per 26 Juni 2020. Indonesia menempati peringkat ketiga negara dengan jumlah kematian tertinggi di Asia setelah India dengan 18.225 kematian dan Iran yang mencatat 11.106 kematian. Tujuan penelitian untuk menganalisis faktor yang mempengaruhi CFR Covid-19 di Indonesia. Penelitian ini merupakan penelitian deskriptif eksploratif kuantitatif dengan pendekatan Expost fakto. Analisis regresi linear berganda dilakukan dengan bantuan SPSS. Data yang dianalisis adalah data kejadian Covid-19 di Indonesia sejak Maret 2020 hingga Desember 2021. Hasil penelitian menunjukkan terdapat tiga faktor (Jumlah Kasus baru, Jumlah Kematian Akibat Covid-19, dan Reproduction Rate) yang mempengaruhi CFR Coronavirus di Indonesia, dengan model persamaan CFR = 0,004 – 0,000001513 Kasus Baru + 0,00002381 Kematian + 0,038 Reproduction Rate. Untuk menekan CFR akibat Covid-19 melalui penekanan kasus baru dan kematian yang terkonfirmasi serta pembatasan penularan kasus baru adalah dengan memperbaiki dan menyiapkan seluruh sistem kesehatan di Indonesia. Puskesmas berperan mendidik masyarakat untuk menerapkan protokol kesehatan serta memaksimalkan 3 T (testing, tracing, treatment) protokol kesehatan 3M, maupun vaksinasi.
Serum Progranulin Levels as Markers of Mammary Tumors in Women Rosa Dwi Wahyuni; Rahma Rahma; Dachruddin Ngatimin; M. Sabir M. Sabir; Abd. Farid Lewa
Jurnal Bidan Cerdas Vol. 6 No. 1 (2024)
Publisher : Poltekkes Kemenkes Palu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33860/jbc.v6i1.3445

Abstract

Introduction: Carcinoma mammae is a malignant tumor that develops from breast cells and has the potential to invade the surrounding tissue (invasive) or metastasize to other parts of the body. While it is more frequently diagnosed in women, there are cases where it is also found in males. Purpose: This study aims to identify variations in serum progranulin levels as distinguishing factors between benign mammary tumors and mammary carcinoma. Method: The research adopts a quantitative approach with a cross-sectional design to ascertain the significance of serum progranulin levels in patients with mammary tumors. The study includes the entire accessible population diagnosed with mammary tumors by clinicians in the Surgical Oncology Department of Dr. Wahidin Sudirohusodo Teaching Hospital in Makassar, with a sample size of 78 individuals. Normality is assessed using the Kruskal-Wallis test, and differences are examined through the Mann-Whitney test. Result: A substantial difference exists in serum progranulin levels among breast carcinoma patients with benign mammary tumors and the control group (P<0.001). The mean difference in benign tumors is 121.08±56.84, whereas in breast carcinoma, it is 239.54±34.79. Conclusion: Serum progranulin levels can be employed as a potential alternative for diagnostic support in the early detection of both benign mammary tumors and mammary carcinoma.
Hubungan Diabetes Melitus Tipe 2 dengan Kadar Profil Lipid Pasien di RSUD Undata Provinsi Sulawesi Tengah Tahun 2023 Saladin Ardhya Prawira AS; Wahyuni, Rosa Dwi; Sumarni; Putrie, Intania Riska
Medika Tadulako: Jurnal Ilmiah Kedokteran Fakultas Kedokteran Vol. 10 No. 1 (2025): Maret
Publisher : Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Diabetes Melitus Tipe 2 (DMT2) merupakan masalah kesehatan global yang terus meningkat, terutama di negara berkembang seperti Indonesia. Salah satu faktor risiko yang berperan adalah profil lipid, termasuk kolesterol total, LDL, HDL, dan trigliserida. Penelitian ini bertujuan untuk mengeksplorasi hubungan antara DMT2 dan kadar profil lipid pada pasien di RSUD Undata Provinsi Sulawesi Tengah Tahun 2023. Tujuan dari penelitian ini adalah untuk mengetahui hubungan antara Diabetes Melitus Tipe 2 dengan Kadar Profil Lipid pada Pasien di RSUD Undata Provinsi Sulawesi Tengah Tahun 2023. Penelitian menggunakan desain cross-sectional dengan sampel sebanyak 37 pasien yang memenuhi kriteria inklusi dan eksklusi. Data sekunder dari rekam medis pasien digunakan untuk analisis. Uji statistik yang diterapkan meliputi analisis univariat dan bivariat menggunakan Uji Chi-Square untuk menentukan hubungan antarvariabel. Analisis menunjukkan bahwa tidak terdapat hubungan yang signifikan antara Diabetes Melitus Tipe 2 dengan kadar kolesterol total (p = 0,418), LDL (p = 1,000), HDL (p = 1,000), maupun trigliserida (p = 0,454). Penelitian ini tidak menemukan hubungan signifikan antara Diabetes Melitus Tipe 2 dengan kadar profil lipid pasien. Hasil ini menunjukkan bahwa faktor lain seperti genetika, metabolisme, dan gaya hidup mungkin lebih berperan dalam pengaruh profil lipid pada pasien Diabetes Melitus Tipe 2 di RSUD Undata Provinsi Sulawesi Tengah Tahun 2023.
Co-Authors A Fahira Nur Abd. Farid Lewa Adhar Arifuddin Adhyanti Agus Alim Abdullah Ari Setiawan Arief, Afriani Arifuddin, Hikmayanti Aristo Aristo Aristo Ary Anggara Badaruddin, Rahma Dachruddin Ngatimin Dachruddin Ngatimin Darma Ariany Fahmi Hafid Fajriah, Rasyika Nurul Hidayanti Arifuddin Indah Fitriyani Intania Riska Putrie, Intania Riska M. Sabir M. Sabir M. Sabir Mansyur Arif Mochammad Hatta Muh. Ardi Munir Muhammad Nasir Nur Asmar Salikunna Nur Eka Dyastuti Nur, Makmur Jaya Nurdin Rahman Rahma Rahma Rahma Rahman, Mega Mutia Ramadhan, Moh Zainul Reny Arniwaty Lamadjido Ressy Dwiyanti Sabir Sabir Saladin Ardhya Prawira AS Sarifuddin Sri Wulan, Sri SUMARNI Sumarni Suriati Tri Setyawati Vera Diana Towidjojo Yayuk Eka Cahyani Yuli Prihatni