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All Journal Jurnal Kedokteran Syiah Kuala The Indonesian Journal of Public Health The Indonesian Biomedical Journal JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Indian Journal of Forensic Medicine & Toxicology KESANS : International Journal of Health and Science Vision Science and Eye Health Journal Prominentia Medical Journal Ophthalmologica Indonesiana Folia Medica Indonesiana
Komaratih, Evelyn
Departemen Ilmu Kesehatan Mata, Fakultas Kedokteran, Universitas Airlangga, Surabaya, Jawa Timur
Biochemistry, Genetics & Molecular Biology Chemistry Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Physics Public Health Veterinary

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Risk Factor Pattern of Graves’ Ophthalmopathy at Dr. Soetomo General Academic Hospital, Surabaya, Indonesia Akbar, Royhan; Mudjanarko, Sony Wibisono; Komaratih, Evelyn; Ardiany, Deasy
JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Vol. 16 No. 2 (2025): Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/juxta.V16I22025.162-167

Abstract

Highlights: Female patients are more likely to suffer from GO. Most GO patients have high thyroid levels (hypothyroidism).   Abstract Introduction: Graves' ophthalmopathy (GO) is an autoimmune condition that extends beyond the thyroid gland. The development of GO may be influenced by various risk factors, some of which may interact with each other. This study aimed to identify the most prevalent risk factors for patients with GO from 2019 to 2022 at Dr. Soetomo General Academic Hospital, Surabaya. Methods: This study employed a descriptive cross-sectional design, examining 150 patients who met the inclusion and exclusion criteria. This study measured the age, gender, and systemic thyroid status of all patients. This study used Microsoft Word and Microsoft Excel for Mac version 16.87 to process data. Results: Between 2019 and 2022, 150 patients were diagnosed with GO at Dr. Soetomo General Academic Hospital, Surabaya. The condition was more prevalent in females than males, and the most common age group affected was between 30 and 50 years old. Additionally, 72% of patients with GO also had hyperthyroidism. Conclusion: Graves' ophthalmopathy was more prevalent in female patients, aged between 30 and 50 years old, with the majority having hyperthyroidism. Future studies should be conducted on the patterns of GO risk factors on a larger scale to more accurately represent the disease in the general population.
CORRELATION OF VISUAL FIELD LOSS TO ACTIVITIES OF DAILY LIVING DISTURBANCE ON GLAUCOMA OUTPATIENTS IN SURABAYA Pryandhini, Pradistya Astri; Primitasari, Yulia; Setiawati, Yunias; Komaratih, Evelyn
The Indonesian Journal of Public Health Vol. 20 No. 2 (2025): THE INDONESIAN JOURNAL OF PUBLIC HEALTH
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/ijph.v20i2.2025.354-365

Abstract

Introduction: Glaucoma is known as a thief of sight due to its progressive visual field loss with symptoms typically manifesting only at advanced stages. Visual field loss, particularly peripheral vision, can affect patients’ quality of life (QoL) in performing activities of daily living. Glaucoma cases are predicted to rise by 74% worldwide between 2013 and 2040. Aims: Assess the correlation between the degree of visual field loss and disturbance in activities of daily living in glaucoma outpatients. Methods: A total of 60 patients from Dr. Soetomo General Academic Hospital were interviewed using the NEI VFQ-25 on near vision, distance vision, peripheral vision, social function, driving, and dependency subscales. Visual field loss was assessed using the Humphrey Visual Field Analyzer (HFA) and categorized based on the Hodapp, Parish, and Anderson (HPA) classification using the better-eye mean deviation value. Meanwhile, Spearman’s rank correlation was used to determine the correlation between the patients’ visual field loss and NEI VFQ-25 interview results. Results: Significant moderate correlations were observed between visual field loss and the social function (r = 0.545) and dependency (r = 0.483) subscales. Significant weak correlations were observed in the near vision (r = 0.351), distance vision (r = 0.383), and peripheral vision (r = 0.398) subscales. An insignificant weak correlation was observed in the driving subscale (r = 0.262). Conclusion: Visual field loss in glaucoma patients is associated with impaired performance in activities of daily living, with the severity of limitation increasing in line with the progression of visual field loss.
CONQUERING THE AMBIGUITY OF OPTIC ATROPHY IN NORMAL TENSION GLAUCOMA: FROM MYSTERY TO MASTERY: Poster Presentation - Case Report - Resident Hakim, Affannul; Komaratih, Evelyn; Nurwasis; Primitasari, Yulia
Majalah Oftalmologi Indonesia Vol 49 No S2 (2023): Supplement Edition
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/nha7y421

Abstract

Introduction : The dilemma in diagnosing glaucoma often arises when optic atrophy is found alongside nonspecific glaucomatous findings and normal intraocular pressure (IOP), particularly in cases of normal tension glaucoma (NTG). This gray zone often leads to doubt and misdiagnosis. Case Illustration : A 70-year-old man previously diagnosed with idiopathic bilateral optic atrophy complained of blurred vision in both eyes. The visual acuity was 5/5 in the right eye (RE) and hand movement in the left eye (LE). Both eyes had normal IOP, open angles with Sampaolesi lines on gonioscopy, fibrin deposits at pupillary margins, and a large cup-to-disc ratio with baring and peripapillary atrophy on funduscopy. The OCT examination revealed thinning in the ONH-RNFL, ILM-RPE, and GCL-IPL complexes. HFA revealed tunnel vision in RE and general depression in LE. The patient was suspected of having NTG. We performed BMO-MRW (less than 100 ?m in both eyes) and 24-hour ocular perfusion pressure (OPP) measurements (less than 50 mmHg at night) to support the diagnosis. Discussion : The BMO-MRW examination is a new parameter that can help establish the diagnosis of glaucoma. A thin BMO-MRW finding suggests that optic atrophy originates from glaucoma. It is important to perform a comprehensive examination in cases of NTG to identify risk factors and prevent the development of glaucoma. Decreased OPP to less than 50 mmHg and PEX syndrome may be risk factors for NTG. Conclusion : In cases of doubtful optical atrophy, it is important to consider the possibility of NTG by performing a comprehensive examination, including BMO-MRW and twenty-four hour OPP measurements.
ANGLE RECESSION, THE SEQUELA OF EIGHT-BALL HYPHEMA AFTER SPRAYED BY FIRE HYDRANT: A CASE REPORT: Poster Presentation - Case Report - Resident Asti, Annisa Kinanti; Komaratih, Evelyn; Nurwasis; Primitasari, Yulia
Majalah Oftalmologi Indonesia Vol 49 No S2 (2023): Supplement Edition
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/gkke0y72

Abstract

Introduction : Hyphema results from damage to the blood vessels of the iris or anterior ciliary body after blunt trauma, and in 56–100% of cases can occur angle recession. Case Illustration : A 40-year-old man complaints of pain and blurred left eye after being sprayed by a high-pressure fire hydrant five hours before coming to the emergency room. Visual acuity was 20/20 and hand movement in right and left eye, IOP is 13 mmHg and 18 mmHg in both eyes. Subconjunctival bleeding, conjunctival and pericorneal injections were found with punctate fluorescein test in the left eye. The cornea was edema and the anterior chamber was full of hyphema. Five days after being hospitalized and treated with topical atropine, antibiotics, and steroid in combination with oral tranexamic acid, the visual acuity was 5/6.5 and the hyphema was resolved. The IOP elevated after 1-6 weeks of follow-up in the outpatient clinic then timolol eyedrops were given. Gonioscopy showed widening of CBB, torn iris processus 2 clock hours in the inferior quadrant. The antiglaucoma medication was stopped due to the controlled IOP in the end episode of the treatment. Discussion : Angle recession involves a tear between the longitudinal and circular muscle fibres of the ciliary body. Medication is needed to control the IOP, while surgical management only indicated in cases where medical treatment fails to control the IOP and risk of progressive visual loss. Conclusion : Angle recession can occur after blunt eye trauma with hyphema and IOP control is needed to prevent the development of secondary glaucoma.
GLAUCOMA SECONDARY TO NONSPECIFIC ORBITAL INFLAMMATION: A DIAGNOSIS NOT TO OVERLOOK: Poster Presentation - Case Report - Resident Prakoeswa, Camilla Amanda; Komaratih, Evelyn; Fatmariyanti, Susy
Majalah Oftalmologi Indonesia Vol 49 No S2 (2023): Supplement Edition
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/ft2tnq30

Abstract

Introduction : Nonspecific Orbital Inflammation (NSOI) is an inflammatory condition of unknown etiology manifesting as pain, ocular motility disturbances, eyelid edema, chemosis, and increased intraocular pressure (IOP). We illustrate a case of glaucoma secondary to NSOI and the importance of understanding the cause-effect relationship between the two conditions. Case Illustration : An eighteen-year-old girl presented with severe pain, ptosis, chemosis, ophthalmoplegia, and increased IOP (38 mmHg) despite a leaking trabeculectomy bleb, on the left eye. She was referredwith the diagnosis of primary angle-closure glaucoma (PACG) and a history of twice trabeculectomy surgeries done elsewhere two months before she came to our hospital. She could not move her lefteye nasally five months before the first surgery and felt joint pains for a year. After thorough diagnostics, she was assessed with left eye NSOI and secondary glaucoma with spondyloarthropathy. Oral prednisone 30 mg/day was given to manage the inflammation and the resultant glaucoma. One week follow-up showed an improved condition with decreased IOP (16 mmHg) despite the same anti-glaucoma therapy regimen. Discussion : NSOI can mimic various diseases, making diagnosis challenging. The raised IOP in NSOI is often caused by extraocular muscles and orbital tissue swelling, which compresses the superior and inferior ophthalmic veins, resulting in choroidal circulation problems. The IOP was quickly reduced once the inflammation was managed. This is a case of secondary glaucoma caused by an overlooked NSOI, aggravated by the immunological process in the orbit after trabeculectomy surgeries. Conclusion : Secondary glaucoma should be considered as a differential diagnosis of PACG in patients with NSOI.
The Association Between Glaucoma Severity and Anxiety And Depression in Glaucoma Patients at DR. Soetomo General Hospital, Surabaya, Indonesia Milan Samudera, Raditya Effendi; Komaratih, Evelyn; Konginan, Agustina; Primitasari, Yulia
Jurnal KESANS : Kesehatan dan Sains Vol 5 No 3 (2025): KESANS: International Journal of Health and Science
Publisher : Rifa'Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54543/kesans.v5i3.509

Abstract

Introduction: Glaucoma is a chronic progressive disease and one of the leading causes of blindness worldwide. Vision loss due to glaucoma affects not only the physical aspect but also has an impact on the patient’s mental health. Poor mental condition may influence the success of therapy and reduce the patient’s quality of life. Objective: The objective of this study is to examine the association between the severity of glaucoma and anxiety and depression in the Eye Outpatient Unit of RSUD Dr. Soetomo Surabaya, Indonesia. Method: A cross-sectional study was conducted involving 50 glaucoma patients at the Ophthalmology Outpatient Unit of Dr. Soetomo General Hospital, Surabaya. Mental health status was assessed through interviews using the Hospital Anxiety and Depression Scale (HADS). The Spearman’s rho correlation test was applied to evaluate the association between glaucoma severity and the presence of anxiety and depression. Result and Discussion: Primary Open-Angle Glaucoma (POAG) was the most prevalent type, and most cases were bilateral. Statistical analysis demonstrated a significant correlation between glaucoma severity and anxiety (r = 0.599), between glaucoma severity and depression (r = 0.520), and also between anxiety and depression (p = 0.001). Conclusions: The severity of glaucoma is related to anxiety and depression
The Role of Optical Coherence Tomography (OCT) in Glaucoma: Emphasis on Cirrus HD-OCT Nugraha, Andarisa Rachman; Komaratih, Evelyn
Vision Science and Eye Health Journal Vol. 5 No. 1 (2025): Vision Science and Eye Health Journal
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/vsehj.v5i1.2025.32-38

Abstract

Introduction: Glaucoma is a rapidly growing illness affecting the population, and is the leading cause of irreversible blindness across the world. Losing vision can occur without any warning, which is why the disorder must be managed as soon as it is diagnosed. Glaucoma is diagnosed and managed using several optical tests, and Cirrus high-definition optical coherence tomography (HD-OCT) is among the most important. Purpose: Glaucoma is commonly diagnosed or monitored by changes in the RNFL. This review will explore changes in glaucomatous structures as detected by Cirrus HD-OCT. Structural elements such as the ganglion cell layer (GCL), inner plexiform layer (IPL), and the optic nerve head (ONH) will be the primary focus. Reviews: Glaucoma relies heavily on the Cirrus HD-OCT for detecting RNFL and GCL changes, which can occur five years or more before visual field changes that can threaten vision. The GCL/IPL layers, especially in preperimetric glaucoma, do provide an incredibly high sensitivity for detecting glaucomatous changes. The guided progression analysis (GPA) was developed to allow Cirrus HD-OCT to track disease progression over time without the identified 'normative databases'. Nevertheless, caution is needed when interpreting GCL/IPL changes in older individuals with macular degeneration. Conclusions: Cirrus HD-OCT is essential for early detection and glaucoma monitoring, offering valuable insights into structural changes in the RNFL, GCL/IPL, and ONH. The use of GPA enhances disease progression monitoring. Future research should focus on artificial intelligence and the creation of localized normative databases to further optimize glaucoma diagnosis and patient care.
Profile of Secondary Glaucoma at a Tertiary Hospital in East Java Komaratih, Evelyn; Rindiastuti, Yuyun; Primitasari, Yulia
Folia Medica Indonesiana Vol. 56, No. 1
Publisher : Folia Medica Indonesiana

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Abstract

Glaucoma is the leading cause of irreversible blindness. The aim of this study was to review the profile of secondary glaucoma cases visiting a tertiary hospital in East Java. This is retrospective observational study, completed case records of new patients with secondary glaucoma who presented to glaucoma clinic from January 2014 to April 2016 were included. Out of the 363 case records screened, 66 cases were found to eligible for inclusion. The evaluation included a detailed history and examination performed including vision, anterior segment examination, intraocular pressure (IOP), gonioscopy, and fundus evaluation. Diagnosis of secondary glaucoma was made on the basis of presence of a secondary cause for presence of raised IOP. 66 cases were eligible for inclusion in the study, most of the cases was occurred in the range age 21-50 years. The male female ratio was 1.3:1. Frequent causes of secondary glaucoma were lens factor 30.8%, steroid induced 29.5%, uveitic 20.5%, neovascular15.4%, and surgical complication 3.8%. Most patients with secondary glaucoma have poor vision < 0.1 with high IOP at presentation. Assessment and early detection of underlying cause is the key guide to treatment strategy.
The Effect of Subconjunctival Bevacizumab on Angiogenesis in Rabbit Model Nurwasis, Nurwasis; Yuliawati, Diana; Komaratih, Evelyn; Heriyawati, Heriyawati
Folia Medica Indonesiana Vol. 55, No. 4
Publisher : Folia Medica Indonesiana

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Abstract

Bone is an important organ for supports the body that stores reserve of calcium, phosphorus, and other minerals. In fracture conditions where bleeding, soft tissue edema, nerve damage, and blood vessels around the bone damage happen, they can cause the mobilization of these minerals in the surrounding tissue. One of the efforts made in the treatment of these fractures is reconnection, in which it works by filling of bone defect with a matrix and administration of anti-infection. Biomaterial filling in defective bone is thought to accelerate the healing process of bone fracture and prevent osteomyelitis. For this reason, this study evaluates the acceleration of bone fracture healing using natural hydroxyapatite (NHA) bone filler in rabbits with bone defect model. Fracture modeling was performed by surgical technique and drilling of bones with a 4.2 mm diameter to form a defect in the rabbit femur. Bone implant contained bovine hydroxyapatite-gelatin-glutaraldehyde (BHA implant) or bovine hydroxyapatite-gelatin-glutaraldehyde-gentamicin (BHA-GEN implant) that was inserted in bone defects. 27 rabbits were divided into 3 groups: the control group who had bone defect, the bone defect group was given BHA implant and the bone defect group was given BHA-GEN implant. Observation of osteoclast, osteoblast, osteocyte, BALP level, and bone morphological integrity was carried out on the 14th, 28th, and 42nd days after surgery. Histological observation of rabbit femur showed a significant difference on the number of osteoclast, osteoblast and osteocyte in all three groups. The BALP level also showed a significant difference in the group given the natural BHA bone implant compared to the control group on day 14 (p = 0.0361). Based on the result of the X-ray, there was also a better integration of rabbit femur bone in groups with the use of BHA or BHA-GEN bone implant. Thus, it can be concluded that the use of a natural BHA implant can accelerate the process of bone repair in the fracture of rabbit femur. In addition, BHA implants were compatible as a matrix for supporting the bone cell growth.
VARIETY OF STUDY METHODS IN OPHTHALMOLOGY RESIDENCY Abdullah, Muhammad Rizqy; Komaratih, Evelyn
Folia Medica Indonesiana Vol. 61, No. 2
Publisher : Folia Medica Indonesiana

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Abstract

Effective study methods are critical in ophthalmology residency, which must balance cognitive learning with surgical skill development. This systematic review examined non-surgical cognitive strategies and surgical training techniques to inform curriculum design and enhance resident performance. A structured literature search was conducted in PubMed and Scopus (2016–2025) using keywords (“study method” OR “effective study” OR “learning strategy” OR “educational intervention” OR “training approach”) AND (“ophthalmology residency” OR “resident education”). After screening and applying eligibility criteria, 17 studies were included. Methods were categorized as non-surgical (n = 5) and surgical learning (n = 12). This review revealed that non-surgical strategies, including residents-as-teachers programs, journal clubs, and structured assessments, were associated with improved engagement, knowledge retention, and board exam performance. Surgical training methods, such as wet labs, mannequin simulators, remote virtual labs, enhance psychomotor skills and procedural competence. Resident-performed surgeries showed educational benefits but suggested that students require close supervision. In conclusion, effective ophthalmology residency training integrates structured cognitive technique with simulation-based surgical practice. Active learning improves academic performance, while controlled surgical simulations of these methods across programs may optimize educational outcomes.
Co-Authors Abdullah, Muhammad Rizqy Akbar, Royhan Alyssa Claudia Valerie Gunawan Ardiany, Deasy Asti, Annisa Kinanti Cita Rosita Sigit Prakoeswa Ferdian Ramadhan Hakim, Affannul Herdina Ramadhani Heriyawati, Heriyawati Indriaswati, Dyah Kusworini Jamaluddin Jamaluddin Karunika, Anindya Ramadian Kevin Anggakusuma Hendrawan Konginan, Agustina Listya Dyah Rihardini Maria Jessica Rachman Milan Samudera, Raditya Effendi Ni Made Inten Lestari Ni Putu Ayu Reza Dhiyantari Nugraha, Andarisa Rachman Nurwasis Nurwasis Nurwasis, Nurwasis Prakoeswa, Camilla Amanda Primitasari, Yulia Pryandhini, Pradistya Astri Rozalina Loebis, Rozalina Setiawati, Yunias Sony Wibisono Subagiono, Arya Agung Hari Suparman Suparman Susy Fatmariyanti Titiek Ernawati Titiek Ernawati Umiastuti, Pirlina Widyati, Dyah Ratri Wilson Christianto Khudrati Wilson Christianto Khudrati Yuliawati, Diana Yuyun Rindiastuti Yuyun Rindiastuti Zuhria, Ismi