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Wound Healing Potency of Edible Bird’s Nest Jessica Alysia; Maureen Miracle Stella; Maureen Widjaja; Lorettha Wijaya
Indonesian Journal of Global Health Research Vol 7 No 1 (2025): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v7i1.4065

Abstract

Edible bird's nest (EBN) or swiftlet's nest has recently been used extensively in regenerative medicine. This study aims to give a more thorough overview on the efficacy of EBN as a wound-healing agent. Method: We searched literature through several databases: Google Scholar, PubMed, Proquest, JSTOR, EBSCOhost, and SAGE. The keywords used were "bird nest, scar, wound healing" and their synonyms. The inclusion criteria were original articles written in English and assessed the effects of EBN in the wound healing process. We found 9 in vitro studies and 4 in vivo studies reporting wound healing effect of EBN, both macroscopically and microscopically. EBN could increase wound healing process through several mechanisms, such as cell proliferation, anti-oxidants, anti-inflammation, increased collagen synthesis, and tissue hydration. EBN has the potential to be used as a natural bioactive agent to increase the wound healing process.
Eruptive Xanthoma in Acute Pancreatitis: A Systematic Review of Case Reports Yonatan, Eric Ricardo; Alexander, Leonardo; ., Valencia; Wijaya, Lorettha
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy Vol 26, No 1 (2025): VOLUME 26, NUMBER 1, April, 2025
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24871/261202510-18

Abstract

Background: Eruptive xanthoma is a skin lesion caused by localized lipid deposits in the dermis, characterized by an eruption of yellow papules typically present on the buttocks, shoulders, and extensor skin surfaces of the extremities. Eruptive xanthoma is associated with acute pancreatitis as a result of hypertriglyceridemia or other lipid disorders. This study aims to discuss several case reports of patients with eruptive xanthomas and acute pancreatitis to provide descriptions and similarities between cases.Methods: This systematic review was conducted using Preferred Reporting Items for Systematic Reviews and Meta-analysis guidelines. Case reports about eruptive xanthoma and acute pancreatitis are included in this systematic review. The literature search was done using PubMed, EBSCOHost, ProQuest, and Google Scholar. Critical evaluation for case reports by Joanna Briggs Institute is used for risk of bias assessment.Results: A literature search identified 6 case reports after eliminating irrelevant and duplicated studies. All assessed case reports reported similar dermatologic manifestations of eruptive xanthoma. Majority of patients reported severe acute abdominal pain as the main symptom of acute pancreatitis. All studies showed an increased level of lipid profiles, and other diagnostic workups support the diagnosis of eruptive xanthoma and acute pancreatitis. Risk of bias in case reports included was acceptable.Conclusion: Eruptive xanthomas can be found in patients with acute pancreatitis with correlation to hypertriglyceridemia and lipid disorders. Proper recognition, diagnosis, and treatment for eruptive xanthoma and acute pancreatitis should be kept in mind for practitioners.Keywords: Eruptive xanthoma, acute pancreatitis, systematic review
Polusi Udara dan Dermatitis Atopik: Suatu Tinjauan Literatur Wikanto, Jessica Rosemary; Wijaya, Lorettha; Dewantara, Jason; Lopulalan, Anastasya Anjeli; Regina, Regina
Jurnal Kesehatan Lingkungan Indonesia Vol 24, No 3 (2025): Oktober 2025
Publisher : Master Program of Environmental Health, Faculty of Public Health, Diponegoro University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jkli.65719

Abstract

Latar belakang: Polusi udara di Indonesia saat ini cukup tinggi seiring dengan meningkatnya urbanisasi dan industrialisasi. Paparan polusi udara dapat merusak fungsi perlindungan kulit dan diduga berhubungan dengan dermatitis atopik. Studi ini bertujuan untuk mengulas perkembangan studi pengaruh polusi udara terhadap dermatitis atopik.Metode: Studi ini merupakan tinjauan literatur dengan menggunakan basis data Pubmed, ClinicalKey, EBSCO, dan ProQuest yang terbit dalam 5 tahun terakhir dan berbahasa Inggris. Kata kunci yang digunakan adalah “particulate matter AND atopic dermatitis”.Hasil: Hasil studi menunjukkan bahwa polusi udara dapat merusak sawar kulit dan memicu respon peradangan, sehingga memicu dermatitis atopik. Paparan polusi udara pada masa prenatal dan usia dini berhubungan dengan peningkatan insidensi dermatitis atopik pada anak-anak. Paparan jangka pendek terhadap kadar polutan tinggi dapat meningkatkan risiko kekambuhan dermatitis atopik. Prevalensi dermatitis atopik juga terus mengalami peningkatan di negara-negara berkembang.Simpulan: Studi ini menyimpulkan bahwa polusi udara dapat menjadi pemicu ataupun memperparah gejala dermatitis atopik. ABSTRACT Title: Air pollution and atopic dermatitis: A literature reviewBackground: Currently, air pollution in Indonesia is quite high along with increasing urbanization and industrialization. Exposure to air pollution may cause damage to skin protective function and may be related to atopic dermatitis. This paper aims to review the progress of studies concerning the relationship between air pollution and atopic dermatitis. Method: Studies, which were published in English within the last 5 years, were obtained through databases (Pubmed, ClinicalKey, EBSCO, and ProQuest). The keywords used are“particulate matter AND atopic dermatitis”Result: Results show that air pollution may damage skin barrier and trigger inflammatory response, thereby inducing atopic dermatitis. Prenatal and early childhood exposure to air pollution were associated with increasing incidence of atopic dermatitis in children. Acute exposure to high pollutant causes the increase of atopic dermatitis relapse. The prevalence of atopic dermatitis is also increasing in developing countries. Conclusion: This study concluded that air pollution may trigger or worsen the symptoms of atopic dermatitis.