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Correlation between score for allergic rhinitis and quality of life in chronic rhinitis patients Asti Widuri; Tri Wahyuliati; Winda Retno Ningrum
Oto Rhino Laryngologica Indonesiana Vol 51, No 2 (2021): VOLUME 51, NO. 2 JULY - DECEMBER 2021
Publisher : PERHATI-KL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32637/orli.v51i2.446

ABSTRACTBackground: Allergic rhinitis is a chronic inflammatory condition of the nasal mucosa that occurs as an Imunoglobulin E (IgE) mediated reaction after provocation of allergen. The prevalence of rhinitis in Indonesia reaches 12.4% and still rising. Chronic rhinitis can affect the quality of life, especially daily activities and sleep disturbances. Purpose: This study aimed to determine the correlation between the Score for Allergic Rhinitis (SFAR) and the patient’s quality of life (QOL) using allergic rhinitis mobile phone application. Method: This was an observational analytic research using cross sectional method. The number of samples was 46 with predetermined inclusion and exclusion criteria. The research instrument used was a mobile phone application of SFAR and for quality of life was Visual Analog Scales (VAS) questionnaire. Data analysis was using Shapiro-Wilk for normality test and contingency coefficient test to determine the correlation between variables. Result: The result showed that there was a significant correlation between the Score for Allergic Rhinitis and the quality of life in chronic rhinitis sufferers (p = 0.000). The correlation had uni-direction and moderate strength (r = 0.567). There were 52.17% respondents who stated that rhinitis complaints would be reduced after using nasal drugs/sprays. And for the VAS parameter, the highest number given was 0 in 45.65% respondents, which meant that they did not feel any discomfort. Conclusion: There was a significant correlation between SFAR and quality of life AR sufferers with moderate strength and uni-direction.Keywords: Score for Allergic Rhinitis, quality of life, rhinitis, mobile applicationABSTRAKLatar belakang: Rinitis alergi adalah kondisi inflamasi kronis pada mukosa hidung sebagai reaksi yang dimediasi Imunoglobulin E (IgE) setelah provokasi alergen. Prevalensi rinitis di Indonesia mencapai 12,4 % dan akan terus meningkat. Rinitis kronik dapat memengaruhi kualitas hidup terutama aktivitas sehari-hari dan gangguan tidur. Tujuan: Penelitian ini bertujuan untuk mengetahui korelasi Score for Allergic Rhinitis (SFAR) dengan kualitas hidup penderita menggunakan aplikasi rinitis alergi pada telepon genggam. Metode: Penelitian ini berupa analitik observasional dengan desain cross sectional. Sampel yang digunakan sebanyak 46 responden dengan kriteria inklusi dan eksklusi yang sudah ditentukan. Instrumen penelitian menggunakan aplikasi telepon genggam berisi kuisioner SFAR dan kualitas hidup dengan Visual Analog Scales (VAS). Analisis data menggunakan Shapiro-Wilk untuk uji normalitas dan uji koefisien kontingensi untuk mengetahui korelasi antar variabel. Hasil: Didapatkan hasil berupa hubungan korelasi yang bermakna antara skor SFAR dengan kualitas hidup penderita rinitis kronik (p=0,000). Hubungan korelasi tersebut memiliki satu arah dan kekuatan yang sedang (r=0,567). Diperoleh pernyataan dari 52,17% responden bahwa keluhan rinitis akan berkurang setelah minum obat/menggunakan semprot hidung. Untuk parameter VAS didapatkan hasil bahwa angka terbanyak yang diberikan adalah 0 pada 45,65% responden, yang berarti tidak merasakan ketidaknyamanan. Kesimpulan: Terdapat korelasi bermakna antara SFAR dan kualitas hidup penderita AR dengan kekuatan hubungan sedang dan satu arah.Kata kunci: Score for Allergic Rhinitis, kualitas hidup, rinitis, aplikasi telepon genggam

Gambaran Uji Cukit Kulit Pada Mahasiswa Fakultas Kedokteran Universitas Muhammadiyah Yogyakarta dengan Gejala Rhinitis Alergi Rizka Fakhriani; Tri Wahyuliati; Asti Widuri
Medica Arteriana (Med-Art) Vol 2, No 2 (2020): Desember 2020
Publisher : University of Muhammadiyah Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26714/medart.2.2.2020.115-120

Latar Belakang: Rhinitis alergi (RA) adalah penyakit saluran napas atas yang disebabkan oleh reaksi inflamasi yang diperantarai IgE setelah adanya pajanan alergen. Uji cukit kulit merupakan tes standar yang digunakan dalam menegakkan diagnosis RA. Uji cukit kulit memberikan informasi keberadaan IgE spesifik terhadap protein dan peptide antigen atau yang dikenal dengan alergen.Tujuan: Mengetahui gambaran hasil pemeriksaan uji cukit kulit pada mahasiswa fakultas kedokteran Universitas Muhammadiyah Yogyakarta dengan gejala rhinitis alergi.Metode penelitian: Deskriptif melalui metode potong lintang.Hasil: Sebanyak 28 orang dengan gejala rhinitis alergi telah menjalani pemeriksaan uji cukit kulit. dengan jenis kelamin perempuan sebanyak 21 orang, laki-laki sebanyak 7 orang. Jenis alergen terbanyak yang didapatkan adalah tungau debu rumah dan kacang tanah sebanyak 14 orang (50%). Persentase alergen lain pada hasil uji cukit kulit pada penelitian ini adalah bulu anjing didapatkan pada 13 orang (46,43%), putih telur 13 orang (46,43%), udang 12 orang (42,86%), daging sapi 12 orang (42,86%), kuning telur 12 orang (42,86%), kedelai 12 orang (42,86%), coklat 12 orang (42,86%), kopi 12 orang (42,86%), nanas 12 orang (42,86%), kepiting 11 orang (39,29%), cumi 11 orang (39,29%), ikan air tawar 11 orang (39,29%), teh 11 orang (39,29%), kerang 10 orang (35,71%), tongkol 10 orang (35,71%), daging ayam 9 orang (32,14%), serta susu 8 orang (28,57%).Kata kunci: rhinitis alergi, alergen, uji cukit kulit

DUTCH (Dried Urine Test for Comprehensive Hormones) In Preventing Diseases Related Hormonal Function Asti Widuri; Rizka Fakhriani; Qorry Agustin; Astika Cahyarani
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 6, No 2 (2022): Journal Qanun Medika Vol 6 No 02
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v6i2.9204

Hormones released and absorbed by the human body in a balanced state will help create balance and health, while changes in hormone levels can cause various severe and chronic health problems. Hormone test is a method of measuring hormone levels in the body that can be used to diagnose and treat diseases, monitor patient health as a whole, or prevent the growth of certain health problems. This research might be the information about. the functional hormone test (DUTCH). This study presented a case of a 47 years old woman with history of chronic dysmenorrhea. The functional hormone testing was carried out on days 19-22 of the menstrual cycle in women with a regular period of 28 days. The result of DUTCH test in this patient were dominant 2-OH that she safe from the symptoms of estrogen dominance and low production of 4-OH, the methylation process was fluent so that the risk of cancer-related to estrogen dominance syndrome was low. Hormone examination through urine is intended to see metabolites (metabolic waste) hormones released through urine. By witnessing the estrogen & progesterone metabolites, it can be seen how much risk a person has Estrogen Dominance Syndrome.

UPAYA PENINGKATAN LAYANAN KONSULTASI KESEHATAN DENGAN TELEMEDICINE Asti Widuri; Hafni Zuchra Noor
JMM (Jurnal Masyarakat Mandiri) Vol 5, No 4 (2021): Agustus
Publisher : Universitas Muhammadiyah Mataram

Abstrak: Sejak menyebarnya pandemi infeksi Covid-19 ke Indonesia maka dilakukan upaya pembatasan kegiatan di masyarakat termasuk pelayanan kesehatan. Dampak lain adalah keengganan masyarakat untuk keluar rumah karena disarankan tetap berada dirumah dan penurunan penghasilan karena melemahnya roda perekonomian. Kondisi diatas berpengaruh pada turunnya jumlah kunjungan pasien rumah sakit secara umum maupun khusus di Kucala Medical Center (KMC). Tujuan program pengabdian kemitraan ini untuk meningkatkan kunjungan pasien berupa pelayanan alternatif dengan memberikan konsultasi jarak jauh. Tahapan pengabdian yang dilakukan adalah: tahab pertama dengan pemberian sarana komputer dan internet, tahab kedua dengan pelatihan admin dan dokter, tahab ketiga dengan sosialisasi layanan dengan webinar dan video promosi. Hasil analisis kuesioner tentang pengetahuan dan minat masyarakat menunjukkan 63.8 % pasien sudah mengenal telemedicine, tetapi baru 27.7 % yang pernah menggunakan layanan. Setelah program pengabdian dilaksanakan disimpulkan bahwa telemedicine dapat menjadi alternatif untuk meningkatkan kunjungan KMC berdasar data kuesioner 88.9% masyarakat berminat untuk melakukan telemedicine.Abstract: Since the spread of COVID-19 pandemic to Indonesia, there were limitation of activity including health services. Another impact of the pandemic is the reluctance people to going out home decreased income due to weakening of economy. These conditions impact on patient quantity in general hospital and KMC clinic. Aim of the dedication community programs were to increase patient’s visit by develops the alternative types of services by providing long distance consultation. The steps activity of community services first provided computer and internet facility, second step was training for admin and doctors, thirst step was promotion with online webinar and video promotion. Results from questionnaire about knowledge and interest to telemedicine showed that people 63.8 %, respondent familiar with telemedicine but only 27.7 % had ever used the service. After the program concluded that telemedicine as an alternative for increased KMC visit according to questionnaire that 88.9% public were interested in doing telemedicine.

Correlation between score for allergic rhinitis and quality of life in chronic rhinitis patients Asti Widuri; Tri Wahyuliati; Winda Retno Ningrum
Oto Rhino Laryngologica Indonesiana Vol. 51 No. 2 (2021): VOLUME 51, NO. 2 JULY - DECEMBER 2021
Publisher : PERHATI-KL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32637/orli.v51i2.446

ABSTRACTBackground: Allergic rhinitis is a chronic inflammatory condition of the nasal mucosa that occurs as an Imunoglobulin E (IgE) mediated reaction after provocation of allergen. The prevalence of rhinitis in Indonesia reaches 12.4% and still rising. Chronic rhinitis can affect the quality of life, especially daily activities and sleep disturbances. Purpose: This study aimed to determine the correlation between the Score for Allergic Rhinitis (SFAR) and the patient’s quality of life (QOL) using allergic rhinitis mobile phone application. Method: This was an observational analytic research using cross sectional method. The number of samples was 46 with predetermined inclusion and exclusion criteria. The research instrument used was a mobile phone application of SFAR and for quality of life was Visual Analog Scales (VAS) questionnaire. Data analysis was using Shapiro-Wilk for normality test and contingency coefficient test to determine the correlation between variables. Result: The result showed that there was a significant correlation between the Score for Allergic Rhinitis and the quality of life in chronic rhinitis sufferers (p = 0.000). The correlation had uni-direction and moderate strength (r = 0.567). There were 52.17% respondents who stated that rhinitis complaints would be reduced after using nasal drugs/sprays. And for the VAS parameter, the highest number given was 0 in 45.65% respondents, which meant that they did not feel any discomfort. Conclusion: There was a significant correlation between SFAR and quality of life AR sufferers with moderate strength and uni-direction.Keywords: Score for Allergic Rhinitis, quality of life, rhinitis, mobile applicationABSTRAKLatar belakang: Rinitis alergi adalah kondisi inflamasi kronis pada mukosa hidung sebagai reaksi yang dimediasi Imunoglobulin E (IgE) setelah provokasi alergen. Prevalensi rinitis di Indonesia mencapai 12,4 % dan akan terus meningkat. Rinitis kronik dapat memengaruhi kualitas hidup terutama aktivitas sehari-hari dan gangguan tidur. Tujuan: Penelitian ini bertujuan untuk mengetahui korelasi Score for Allergic Rhinitis (SFAR) dengan kualitas hidup penderita menggunakan aplikasi rinitis alergi pada telepon genggam. Metode: Penelitian ini berupa analitik observasional dengan desain cross sectional. Sampel yang digunakan sebanyak 46 responden dengan kriteria inklusi dan eksklusi yang sudah ditentukan. Instrumen penelitian menggunakan aplikasi telepon genggam berisi kuisioner SFAR dan kualitas hidup dengan Visual Analog Scales (VAS). Analisis data menggunakan Shapiro-Wilk untuk uji normalitas dan uji koefisien kontingensi untuk mengetahui korelasi antar variabel. Hasil: Didapatkan hasil berupa hubungan korelasi yang bermakna antara skor SFAR dengan kualitas hidup penderita rinitis kronik (p=0,000). Hubungan korelasi tersebut memiliki satu arah dan kekuatan yang sedang (r=0,567). Diperoleh pernyataan dari 52,17% responden bahwa keluhan rinitis akan berkurang setelah minum obat/menggunakan semprot hidung. Untuk parameter VAS didapatkan hasil bahwa angka terbanyak yang diberikan adalah 0 pada 45,65% responden, yang berarti tidak merasakan ketidaknyamanan. Kesimpulan: Terdapat korelasi bermakna antara SFAR dan kualitas hidup penderita AR dengan kekuatan hubungan sedang dan satu arah.Kata kunci: Score for Allergic Rhinitis, kualitas hidup, rinitis, aplikasi telepon genggam

Translation and validation of the Indonesian version of the chronic otitis media questionnaire-12 Fakhriani, Rizka; Widuri, Asti; Yudistira, Danu
International Journal of Public Health Science (IJPHS) Vol 13, No 3: September 2024
Publisher : Intelektual Pustaka Media Utama

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11591/ijphs.v13i3.23943

Chronic suppurative otitis media (CSOM) is a pathological disorder affecting the ear, characterized by a persistent and long-lasting middle ear infection accompanied by the absence of an intact tympanic membrane. Multiple measures can be employed to evaluate the quality of life among patients with CSOM. One such instrument is the chronic otitis media questionnaire-12 (COMQ-12), which has demonstrated satisfactory levels of validity and reliability. The utilization of the COMQ-12 questionnaire has the potential to improve the quality of life experienced by CSOM patients. This study aimed to evaluate the validity and reliability of the Indonesian adaptation instrument of the COMQ-12 in patients with CSOM in the Otorhinolaryngology department of multiple hospitals in Yogyakarta. The study was conducted from February to July 2023. The study comprised 48 participants, consisting of 16 males and 32 females. The adapted Indonesian version of the COMQ-12 instrument demonstrates validity and reliability in assessing patients' quality of life with CSOM, as evidenced by a statistically significant r-value of 0.2353. The internal consistency analysis reveals that Cronbach's α coefficient is 0.868. The Indonesian adaptation of the COMQ-12 demonstrates validity and reliability as an assessment tool for measuring the health-related quality of life in patients diagnosed with CSOM.

Acute toxicity of the intranasal administration of Anredera cordifolia extract in Wistar Rats Widuri, Asti; Febriansah, Rifki
Pharmaciana Vol. 14 No. 2 (2024): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/pharmaciana.v14i2.28249

Anredera cordifolia (AC) known as binahong plant in Indonesia is commonly used for traditional medicine since ancients. AC contains of secondary metabolites such as flavonoids that have anti-oxidative, anti-inflammatory, anti-mutagenic and anti-carcinogenic properties. Many flavonoids compound that has anti-inflammatory activity were potential for treatment of nasal inflammatory such as allergic rhinitis. This study aims to evaluate the preclinical safety of acute intranasal administration of AC extract in laboratory wistar rats. Acute toxicity using the intranasal route of administration of AC extract was evaluated on 30 female wistar rats, divided five rats for control, and each five of doses 5%, 10%, 25%, 50% and 75%. Observation during 14 days for the incidence of mortality and signs of toxicity. The AC extract intranasal administration doses at 5%, 10%, 25%, 50% and 75% did not show mortality or treatment related adverse events and did not showed significantly changes on blood profile. The AC extract was found safe until 75% for nasal administration in wistar rats.

Effect of Saline Nasal Irrigation in Patients with Sinonasal Symptoms Widuri, Asti; Fakhriani, Rizka; Daniswara, Deoni
Majalah Kedokteran Bandung Vol 56, No 3 (2024)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15395/mkb.v56.3621

Nasal irrigation with saline is frequently used as an alternative therapy for sinonasal diseases since it effectively reduces sinonasal symptoms and improves the quality of life when measured by various subjective instruments. The mechanisms of action of saline irrigation remain unclear, but some hypotheses attribute the direct physical cleansing of thick mucus, allergens, and pollutants. This study aimed to determine the effect of nasal saline irrigation on the nasal mucosa using the modified Lund-Kennedy endoscopic score as the objective evaluation. This pre-post-experimental study was conducted at PKU Muhammadiyah Gamping Hospital Yogyakarta, Indonesia, from May to June 2023. The study included 18 individuals presenting with sinonasal symptoms. Participants meeting the inclusion and exclusion criteria who provided informed consent were trained in nasal saline irrigation. Patients were assessed at baseline and one week after nasal saline irrigation using endoscopy, TNSS, and MCC time. Results revealed that the mean of endoscopic scores before and after saline irrigation were 6.89±1.1 and 5.33±1.4, respectively (p-value 0.006), while the mean of TNSS scores before and after saline irrigation was 6.17±2.3 and 4.28±2.6, respectively (p-value 0.006). Thus, nasal saline irrigation significantly improves the endoscopy and TNSS scores, but not the MCC time.

Validity and reliability of the Indonesian knowledge, attitude, and practice of allergic rhinitis questionnaire Fakhriani, Rizka; Widuri, Asti; Amsriza, Fadli Robby; Daniswara, Deoni
Science Midwifery Vol 12 No 6 (2025): February: Health Sciences and related fields
Publisher : Institute of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/midwifery.v12i6.1837

Allergic rhinitis (AR) is a typical chronic condition commonly affecting the upper airway. Allergic rhinitis is marked by nasal congestion, rhinorrhea, pruritus, sneezing, and postnasal drip syndrome (PND), which includes eye itching and erythema. This study aims to assess the validity and reliability of the Indonesian version of the knowledge, attitude, and practice (KAP) of the allergic rhinitis questionnaire. The study employed a cross-sectional design. The study included patients with allergic rhinitis who were 18 or older and visited the otorhinolaryngology clinic between January and February 2024. The questionnaire was generated and disseminated using a Google form, and the statistical analysis was performed with SPSS 22.0. The correlation coefficient (r) between all questions on the knowledge dimension was consistently high, ranging from 0.302 to 0.828. The items on the attitude dimension had a strong positive association with the total score, as seen by the high correlation coefficients (all r = 0.962). The practice dimension also exhibited high correlation coefficients, ranging from 0.273 to 0.810 in total score. The questionnaire's validity and reliability have been established, confirming that the Indonesian version is recommended for future studies.

Reconstruction of the auricular rupture: A case report of treatment of ear trauma Daniswara, Deoni; Widuri, Asti; Fakhriani , Rizka
Science Midwifery Vol 13 No 1 (2025): April: Health Sciences and related fields
Publisher : Institute of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/midwifery.v13i1.1909

Auricular rupture is one of the most common ear defects caused by trauma on facial and head regions. Traffic accidents, accidents at home, fights, and human bites are common causes of ear injuries based on several epidemiological studies. In this study, we report a case of ear trauma auricular rupture, with appropriate treatment and the things to watch out for during treatment. A 19-year-old man came to the Emergency Department due to a traffic accident. The results of the vital signs examination were within normal limits, found an injury to the left auris; the wound penetrated the left auris from the Helix to the antihelix with a wound length of approximately 4 cm. Bleeding was controlled with a compression splint using gauze and ligature. The patient underwent elective surgery, which was successful and without complications. Ear trauma involves cartilage is a challenge to treat reconstruction for surgeons. The main treatment for auricular rupture is closure of the open cartilage, skin and prevent complications.

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