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Kajian Peresepan pada Pasien Geriatri dengan Gangguan Sistem Endokrin Cahyaningsih, Indriastuti; Latifah, Faizah Nurul; Maziyyah, Nurul; Orbayinah, Salmah
JSFK (Jurnal Sains Farmasi & Klinis) Vol 10 No 2 (2023): J Sains Farm Klin 10(2), Agustus 2023
Publisher : Fakultas Farmasi Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jsfk.10.2.197-204.2023

Abstract

Pertambahan usia dapat mempengaruhi kinerja fungsi organ tubuh dan berdampak terhadap rentannya populasi geriatri terserang penyakit, diantaranya adalah gangguan pada sistem endokrin. Geriatri memiliki resiko lebih besar untuk mendapatkan terapi polifarmasi sehubungan dengan penyakit dan komplikasi yang dideritanya. Polifarmasi dapat meningkatkan resiko peresepan obat yang tidak tepat atau Potentially Inappropriate Medications (PIMs). Penelitian ini dilakukan untuk mengetahui hasil kajian peresepan obat pada pasien geriatri dengan diagnosis gangguan endokrin. Penelitian ini merupakan penelitian deskriptif observasional dengan desain penelitian menggunakan desain cross–sectional. Pengumpulan data dilakukan secara retrospektif dari 211 rekam medis pasien geriatri yang dirawat inap di salah satu rumah sakit rujukan di Bantul, Indonesia dengan diagnosis gangguan pada sistem endokrin periode tahun 2018. Pengambilan sampel penelitian menggunakan teknik systematic random sampling dengan analisis data mengacu pada Beers Criteria 2019. Hasil penelitian menunjukkan bahwa terdapat 135 (63,9%) pasien dengan peresepan PIMs berdasarkan Beers Criteria 2019 dengan persentase obat terbesar adalah furosemide sebanyak 65 (30,8%) pasien. Dapat disimpulkan bahwa PIMs pada pasien geriatri dengan gangguan sistem endokrin tergolong tinggi sehingga membutuhkan perhatian dari tenaga kesehatan agar peresepan obat dapat aman dan efektif.
Appropriateness and Cost of Prophylaxis Stress Ulcer for Inpatient in the Internal Medicine Department in a Government Hospital: A Cross-Sectional Study Octavia, Mega; Maziyyah, Nurul; Fauziyah, Rima Nurul
Borneo Journal of Pharmacy Vol. 7 No. 1 (2024): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v7i1.4080

Abstract

Guidelines from the American Society of Health-System Pharmacists (ASHP) 1999 prohibit acid-suppressing therapy for stress ulcer prophylaxis (SUP) in patients who are not critically ill. Stress ulcer prophylaxis is not recommended in non-ICU patients with <2 risk factors. Inappropriate use of SUP can increase costs for patients. This study aims to evaluate the use and the cost of SUP. This research was a non-experimental observational study with a cross-sectional approach. Data was collected retrospectively using the consecutive sampling method with a random sampling technique on the medical records of inpatients in the internal medicine ward of Sleman Regional Public Hospital from January to December 2020, totaling 340 samples. The results showed that proton pump inhibitors were the most widely used acid-suppressing drugs, with 45.8%. Furthermore, the histamine-2 receptor antagonist was 42.6%, the sucralfate group was 7.4%, and the antacid group was 4.2%. Of 340 patients, 57 (16.8%) were in the proper indication based on the guidelines, and 283 (83.2%) were under the wrong indication for SUP. They were using SUP with the proper indication so that the therapy could save treatment costs by Rp. 19,933,582. There was a high prevalence of inappropriate SUP prescriptions among inpatients in the internal medicine department; if these drugs were given with the appropriate indications, they could save more on the prophylaxis cost. Clinician pharmacists should develop an effective intervention strategy to reduce inappropriate SUP drugs.