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All Journal PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) Syntax Idea JURNAL JAMU KUSUMA Jurnal Pengabdian Serulingmas (JPS) Serulingmas Health Journal (SHJ) Jurnal Farmasetis Borneo Nursing Journal
Triyo Nova, Triyo
Institute Of Health Science Serulingmas Cilacap
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STANDARDIZATION OF SIMPLICIA AND LIME PEEL EXTRACT Wahyunita Yulia Sari; Muhammad Fauzi Ramadhan; Setyowati Eka Yuniar; Bambang Purwoko; Triyo Nova; Fa'iq Hanif Mubarok
Jurnal Jamu Kusuma Vol. 5 No. 2 (2025): JURNAL JAMU KUSUMA
Publisher : Poltekkes Kemenkes Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37341/jurnaljamukusuma.v5i2.141

Abstract

Lime (Citrus aurantifolia Swingle) is one of the plants that can be used as traditional medicine. Parts of the lime plant that can be used as traditional medicine include the fruit, leaves, and peel. Lime peel waste is known to contain chemical compounds and as a raw material for medicine, standardization is needed to ensure its quality. The 70% ethanol extract of lime peel was made using the maceration extraction method. This study aimed to standardize both simplicia and 70% ethanol extract of lime (Citrus aurantifolia Swingle) peel according to the Indonesian Herbal Pharmacopoeia (2017) guidelines to ensure quality for pharmaceutical raw material applications.Lime peel was processed into simplicia and extracted using maceration with 70% ethanol. Standardization was performed on both simplicia and extract based on specific (organoleptic, phytochemical screening) and non-specific parameters (drying loss, water content, total ash, acid-insoluble ash, ethanol-soluble extract, water-soluble extract, and specific gravity). All analyses were performed in triplicate (n = 3) and statistical significance was tested using SPSS version 26 with a confidence level of 95% (p < 0.05).Both simplicia and extract met the pharmacopoeial requirements and can be recommended as standardized raw materials for herbal pharmaceutical formulations. These findings provide a reference for the quality control of herbal raw materials and promote sustainable utilization of lime peel waste.
Co-Authors Aperilia Maeka Putri Bambang Purwoko Bambang Purwoko Bambang Purwoko Definingsih Yuliastuti Dhina Astuti Dwi Hartanti Dwi Hartanti Fa'iq Hanif Mubarok Fa’iq Hanif Mubarok Fa’iq Hanif Mubarok Hanif Mubarok, Fa’iq Ismi Dafngiatul Ngulum Mubarok, Fa’iq Hanif muchamad amir Muhammad Fauzi Ramadhan Murwiningsih Murwiningsih Priyo Agung Laksana Rina Setyawati Setyowati Eka Yuniar Supriani Supriani Supriani Tjiptasurasa Tjiptasurasa Tjiptasurasa Tjiptasurasa, Tjiptasurasa Wahyunita Yulia Sari Woro Supadmi