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Realitization and Testing of Mini Extruder for Biomaterial Filament in Biomedical Application Whulanza, Yudan
Journal of Energy, Mechanical, Material and Manufacturing Engineering Vol 1, No 1 (2016)
Publisher : University of Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (902.374 KB) | DOI: 10.22219/jemmme.v1i1.4476

Abstract

The use of biomaterials in tissue engineering technique requires an engineered scaffold that allow the cells to be growth. Therefore, a specific biomaterial is required to provide a supportive environment for the seeding cell. This study focused on the design and realization of mini-extruder to produce a biocompatible filament material. Later, the filament is applied in a fused deposition modelling to realize biocompatible scaffold. The extruder uses a single screw extruder of 25mm diameter with compression ratio of 2. Moreover, the extruder has an effective length of 305mm with a screw length ratio of the feed zone and metering zone by 20% and 40%. A forming die used has a diameter of 1.7mm. At the end of the realization step, the device was tested to produce the filament with various parameters which are screw rotational speed, winding speed, temperature and torque. Characterization of the produced filaments were done by measuring the diameter of filaments using the material of polycaprolactone (PCL). The filament results have a range of 0.05-1.48mm in diameter during the testing process.
Experimental and Numerical Evaluation of Mechanical Properties for Carbon Fiber Reinforced Epoxy LY5052 Composite for Prosthesis Structures Mahfud Ibadi; Yudan Whulanza; Herry Purnomo; David N Vicarneltor; Tresna P Soemardi; Gatot Prayogo
Jurnal Teknik Mesin Vol 15 No 1 (2022): Jurnal Teknik Mesin
Publisher : Politeknik Negeri Padang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30630/jtm.15.1.783

Abstract

Carbon Fiber Reinforced Epoxy is a material that is widely used in the manufacture of prosthesis structures. In this research, the carbon fiber used is plain weave-type carbon, while the matrix used is LY5052 epoxy, LY5052 epoxy has advantages such as low viscosity and long pot life making it possible to manufacture large-sized prostheses. The first step in this research is making specimens using the vacuum infusion method and then cutting the specimens with dimensions referring to ASTM D3039. Furthermore, tensile test experiments were carried out with the results obtained that the maximum stress () was 537.15 MPa. As an evaluation, a tensile test simulation was carried out with Finite element analysis using Abaqus software, the material properties used were the results of a tensile test experiment, in the process the mesh selection was carried out by input sizing control many times this was done to determine the accuracy of the results. The tensile test simulation results with abaqus software are 523.3 MPa when compared to the experimental, the difference is only 2.58%. based on experimental and simulation results, the mechanical properties of the Carbon Fiber Reinforced Epoxy LY5052 Composite material are almost the same, so that in the manufacture of prosthesis the mechanical properties data in this study can be used when performing numerical analysis in the prosthesis design process.
Preliminary Study of Potential Bioimplant from Glycerol Plasticized Starch-Microcrystalline Cellulose Composite Galih Rineksa; Yudan Whulanza; Misri Gozan
Journal of Integrated and Advanced Engineering (JIAE) Vol 1, No 1 (2021)
Publisher : Asosiasi Staf Akademik Perguruan Tinggi Seluruh Indonesia (ASASI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51662/jiae.v1i1.10

Abstract

Biodegradable and bio-based substitutes for conventional plastics are on the rise in these past decades. One of the applications of bioplastic is for biomedical implants or bioimplant. Starch was plasticized using glycerol at varying amounts (40% and 60% of dry starch mass) to produce thermoplastic starch (TPS). A reinforcement filler of microcrystalline cellulose (MCC) was used to improve the mechanical properties. The MCC content in this study was also varied (0%, 2%, 4%, and 8% w/w). This paper studies the mechanical properties of starch-MCC composites for their potential as bioimplant. The optimum glycerol and MCC contents from the results are 40% glycerol and 8% MCC with 2.97 MPa tensile strength and 7.20% strain at break. Thus, the sample has the potential application in bioimplant material for trabecular bone replacement, which has an average tensile strength of 2 MPa and strains at a break of 2.5%.
Electrochemical Detection and Spectrophotometry of Dopamine using Commercial Screen-Printed Electrodes Eunike Thirza Hanita Christian; Basari Basari; Siti Fauziyah Rahman; Yudan Whulanza
Journal of Biomedical Science and Bioengineering Vol 2, No 1 (2022)
Publisher : Center for Biomechanics, Biomaterials, Biomechantronics and Biosignal Processing (CBOIM3S)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jbiomes.2022.v2i1.7-13

Abstract

Lab-on-chip is miniaturized devices integrated into a chip which can run one or several analyses which are usually done in laboratory settings, such as biochemical detection. Dopamine is an important neurotransmitter which regulates hormones, control of movement, emotion, attention, and motivation. Excess, lack, and dysregulation of dopamine could cause numbers of diseases and disorders. The technique used to measure and evaluate dopamine usually are expensive to run, require longer time to run, require some technical qualification to run, require expensive equipments, and some are invasive to do. These are the reasons why a lab-on-chip system is needed to make the detection of dopamine concentration faster, easier, and more portable. This paper studied the accuracy of using electrochemical detection to measure the concentration of liquid specimens of dopamine compared to uv/vis spectrophotometry. Electrochemical detection method named cyclic voltammetry was chosen for this study. The hypothesis for this study is that both peak current (ip) and absorbance positively correlate to concentration, therefore both could be used with minimal error margin. For this study, the peak current (ip) and absorbance of different concentrations of liquid specimen of dopamine are measured, and its regression were observed. It was shown that the concentration of liquid specimens of dopamine is linear to both anodic peak current (ipa) and absorbance. Due to the high R2 values of 0.9883, electrochemical detection could be used and implemented to detect dopamine concentration for application of lab-on-chip, as it is more portable and requires less volume of sample compared to spectrophotometry.
Experimental and Numerical Evaluation of Mechanical Properties for Carbon Fiber Reinforced Epoxy LY5052 Composite for Prosthesis Structures Mahfud Ibadi; Yudan Whulanza; Herry Purnomo
Journal of Biomedical Science and Bioengineering Vol 2, No 1 (2022)
Publisher : Center for Biomechanics, Biomaterials, Biomechantronics and Biosignal Processing (CBOIM3S)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jbiomes.2022.v2i1.18-22

Abstract

Carbon Fiber Reinforced Epoxy is one of the materials that is widely used in the manufacture of phosthesis structures. In this study, the carbon fiber used carbon-kyoto type plain weave while the epoxy matrix was LY5052. The maximum stress (s) from the tensile test is 537.15 MPa. Furthermore, tensile test simulation with Finite element analysis simulation using Abaqus software, in the process the selection of mesh through input sizing control determines the accuracy of the results. The simulation results are 523.3 MPa when compared to the experiment the difference is 2.58%
Easy extraction of Ganoderma boninense liquid sample using portable on‐chip device Adella Josephin; Yudan Whulanza; Siti Fauziyah Rahman; Kenny Lischer; Muhammad Imam Surya; Irfan Martiansyah; Wiguna Rahman; Uda Hashim
Indonesian Journal of Biotechnology Vol 29, No 1 (2024)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijbiotech.83645

Abstract

Detecting Ganoderma boninense in Indonesia is crucial for effectively controlling and mitigating the spread of basal stem disease in oil palm fields. While there is ongoing development of tolerant plants, no such plant has been successfully created yet. Consequently, researchers are actively studying detection methods for Ganoderma boninense. One established and highly accurate approach is the use of polymerase chain reaction (PCR) techniques for molecular detection. However, this method requires time‐consuming sample preparation, which can pose challenges in plantation settings. To address this problem, a portable lab‐on‐chip device has been introduced. This technology enables easy and automatic DNA retrieval from liquid samples by absorbing lysed DNA using magnetic beads. An efficient mechanism for manipulating the magnetic bead within the semiconductor has been successfully implemented. The extraction process typically takes around 15 minutes using a modified methodology on the chip device approach. The chip facilitates the retrieval of two samples with a capacity of 120 µL for each sample. The PCR method was utilized to validate the equivalence of the lab‐on‐chip device extraction to the standard extraction method. This represents a promising alternative for expedited and simplified detection of Ganoderma boninense in field conditions.
Optimizing Hot Embossing of Poly(methyl methacrylate) Microfluidic Chip Whulanza, Yudan; Dhira, Pandya; Haryadi, Deni; Soemardi, Tresna P.
Jurnal Teknik Mesin Indonesia Vol. 19 No. 2 (2024): Jurnal Teknik Mesin Indonesia
Publisher : Badan Kerja Sama Teknik Mesin Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36289/jtmi.v19i02.760

Abstract

Microfluidic research become a more important research field in mechanical and bioengineering fields. The application of microfluidic positively relates to the ability to manufacture micro or precision. Nowadays, the manufacturing in this area is aimed at around 100-500 µm. Here, a hot embossing method is reported to realize microchannel with height and width dimensions of 150-300 µm and 600-800 µm, respectively. This study also shows that the margin factor between the mould/dies to the realized dimension is 50-70% and 5-7% for height and width, respectively.
EVALUATING ACETONE AND METHANOL FOR ELECTROPHORETIC DEPOSITION OF SS 316L COATED WITH HYDROXYAPATITE/MULTIWALLED CARBON NANOTUBES DENTAL IMPLANTS: A FOCUS ON CORROSION RESISTANCE Valmelina, Ersyi Arini; Wulan, Praswasti Pembangun Dyah Kencana; Whulanza, Yudan; Adin, Mehmet Şükrü
Jurnal Kimia Riset Vol. 9 No. 1 (2024): June
Publisher : Universitas Airlangga, Campus C Mulyorejo, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jkr.v9i1.56784

Abstract

Dental implants offer a reliable solution for replacing damaged tooth roots. This research investigates the comparative performance of acetone and methanol as suspension media in the fabrication of stainless steel type 316L-based dental implants using the Electrophoretic Deposition (EPD) method, a technique known for its simplicity and cost-effectiveness. Voltage variations of 20V, 30V, and 40V were applied to both acetone and methanol suspensions for a duration of 20 minutes. The morphology of the Hydroxyapatite/Multiwalled Carbon Nanotube (HA/MWCNT) coatings was meticulously characterized using Scanning Electron Microscopy (SEM). Corrosion resistance was evaluated through Potentiodynamic Polarization (PDP) and Electrochemical Impedance Spectroscopy (EIS) techniques. Remarkably, at 30V, a homogeneous and crack-free coating was achieved, demonstrating superior corrosion resistance. This was further corroborated by the resistance values of 23.891 Ω and 114.990 Ω for the acetone and methanol samples, respectively. Additionally, the corrosion rates of 0.075 (mmpy) and 0.0004 (mmpy) for the acetone and methanol samples further emphasized the superiority of methanol as a suspension medium. These findings unequivocally establish methanol as the optimal choice for achieving superior deposition quality and corrosion resistance in the context of the EPD method for stainless steel type 316L-based dental implants.
Addressing Fire Safety, Ground Impact Resistance, and Thermal Management in Composite EV Battery Enclosures: A Review Kaleg, Sunarto; Sumarsono, Danardono Agus; Whulanza, Yudan; Budiman, Alexander Christantho
Automotive Experiences Vol 7 No 3 (2024)
Publisher : Automotive Laboratory of Universitas Muhammadiyah Magelang in collaboration with Association of Indonesian Vocational Educators (AIVE)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31603/ae.12540

Abstract

Lithium-ion batteries are fundamental to modern electric vehicles, offering high energy density, long cycle life, and low self-discharge rates. However, thermal runaway—a critical safety issue involving uncontrolled temperature increases—can lead to fire or explosion. Ensuring flame retardancy is crucial in accidents where battery packs are exposed to external fires. Additionally, battery packs are susceptible to mechanical stresses and potential damage from ground impacts like debris or uneven road surfaces. Effective thermal management significantly impacts capacity and longevity. This review emphasizes the importance of researching flame retardancy, ground impact resistance, and thermal management, especially in composite battery enclosures. Composites serve as a lightweight alternative to metals and help overcome one of the main constraints of EVs, which is weight. Ground impact refers to the physical force battery packs endure during collisions, hitting potholes, debris, or accidents. Therefore, understanding the effects of ground impact on battery enclosures is crucial for design considerations. Effective thermal management is also essential, as it directly affects the performance and safety of Lithium-ion battery packs in EVs.
The Effects of Therapeutic Play for Reducing Impact Hospitalization Pre and School-Age In Hospital: A Systematic Review Setiawati, Santun; Wanda, Dessie; Agustini, Nur; Whulanza, Yudan; Keliat, Budi Anna
Poltekita: Jurnal Ilmu Kesehatan Vol. 18 No. 3 (2024)
Publisher : Poltekkes Kemenkes Palu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33860/jik.v18i3.3722

Abstract

This systematic review aimed to identify the effectiveness of therapeutic play in reducing the impact of hospitalization on pre and school-aged children. Five databases were searched (ClinicalKey Nursing, Scopus, Sage Journals, ScienceDirect, and PubMed) for articles published between 2019 and 2023. Six RCT studies from Turkey met the inclusion criteria and were assessed for quality using the JBI Critical Appraisal Checklist. The therapeutic play interventions included goldfish therapy, educational animated films, finger puppet play, music and kaleidoscope therapy, cartoon-assisted endoscopy preparation packages, and buzzy, jet lidocaine, bubble-blowing, and aromatherapy. The duration of the interventions varied. The outcomes measured were anxiety, fear, pain, emotional and psychological well-being, and postoperative nausea and vomiting. The results showed that therapeutic play significantly reduced anxiety (50% of studies), fear (100%), and pain (50%) in children undergoing hospitalization or medical procedures. Goldfish therapy also improved emotional and psychological well-being. No significant differences were found in postoperative vomiting and nausea. The most effective interventions were goldfish therapy, educational animated films, and finger puppet play. In conclusion, therapeutic play is a beneficial nursing intervention for reducing the negative impacts of hospitalization on children aged 3-12 years. Recommendations include implementing therapeutic play in pediatric hospital settings and conducting further research to expand the types of therapeutic play available.