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All Journal Farmaka Jurnal Surya Medika JMM (Jurnal Masyarakat Mandiri) Abdimas Umtas : Jurnal Pengabdian kepada Masyarakat Jurnal Ilmu Kefarmasian Indonesia Journal of Experimental and Clinical Pharmacy (JECP) IICSDGs Jurnal Katalisator
PRISCA SAFRIANI WICITA
Poltekkes Kemenkes Gorontalo
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Granul Effervescent Kombinasi Bunga Telang (Clitoria ternatea) dan Jeruk Kalamansi (Citrus microcarpa) Sebagai Alternatif Minuman Kesehatan Putri, Nurwigya Mohamad; Slamet, Nangsih Sulastri; Wicita, Prisca Safriani; Imran, Arlan K
Journal of Experimental and Clinical Pharmacy (JECP) Vol 1, No 1 (2021): February, 2021
Publisher : Poltekkes Kemenkes Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52365/jecp.v1i1.196

Abstract

Bunga telang (Clitoria ternatea) adalah tanaman yang memiliki potensi farmakologis sebagai antioksidan, antimikroba, antiparasit, anti-inflamasi, antikanker, antihistamin. Jeruk kalamansi (Citrus microcarpa) merupakan tanaman yang sangat kaya akan mineral dan vitamin C sehingga sangat baik digunakan untuk bahan baku minuman kesehatan. Sediaan granul effervescent adalah hasil dari gabungan senyawa asam dan basa yang bila ditambahkan dengan air (H2O) akan bereaksi melepaskan karbon dioksida (CO2), sehingga efek ini akan menghasilkan buih pada sediaan. Tujuan dari penelitian ini adalah untuk memanfaatkan bunga telang dan jeruk kalamansi  sebagai bahan aktif dan untuk menghasilkan sediaan granul effervescent sebagai alternatif minuman kesehatan. Ekstrak bunga telang diperoleh dari metode ekstraksi sederhana dengan cara diblender menggunakan air (1:3). Sari jeruk kalamansi diperoleh dari perasan buahjeruk kalamansi. Hasil penelitian menunjukkan bahwa sediaan granul effervescent kombinasi bunga telang dan jeruk kalamansi ini memiliki warna granul putih keunguan dan larutan biru muda bening serta memiliki bau dan rasa kombinasi bunga telang dan jeruk kalamansi, waktu dispersi yang memenuhi persyaratan waktu larut yakni 1 menit 4 detik dan indeks kompresibilitas 13,3%. Berdasarkan penilaian panelis dari parameter tekstur, warna, aroma dan rasa menunjukkan rata-rata 4,3 dengan  kategori suka. Telang flower (Clitoria ternatea) is a plant that has the potential pharmacologically as antioxidant, antimicrobial, antiparasitic, anti-inflammatory, anticancer, antihistamine. Kalamansi (Citrus microcarpa) is a plant that is very rich in minerals and vitamin C so it is very good for use as raw material for health drinks. Granule preparation effervescent is the result of a combination of acid and base compounds which when added with water (H2O) will react to release carbon dioxide (CO2), so this effect will produce foam on the preparation. The purpose of this research is to utilize the telang flower and calamansi as an active ingredient and to produce granules effervescent as an alternative to health drinks. Pea flower extract obtained from a simple extraction method by means of a blender use water (1:3). Calamansi juice is obtained from the juice calamansi. The results showed that the granule preparations This effervescent combination of telang flower and calamansi has purplish white granule color and clear light blue solution and has the smell and taste of a combination of telang flower and calamansi, time dispersion that meets the requirements for dissolving time of 1 minute 4 seconds and a compressibility index of 13.3%. Based on the panelist's assessment of texture, color, aroma and taste parameters showed an average of 4.3 with likes category.
Skrining Fitokimia dari Ekstrak Metanol Akar Kelor (Moringa oleifera L.) Basri, Insyira Fadliana; Mohamad, Fihrina; Slamet, Nangsih Sulastri; Imran, Arlan K.; Daud, Rizka Puji Astuti; Yunus, Fitriah Ayu Magfirah; Wicita, Prisca Safriani; Basri, Rakhmadhana Fitraeni
Journal of Experimental and Clinical Pharmacy (JECP) Vol 2, No 2 (2022): August 2022
Publisher : Poltekkes Kemenkes Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52365/jecp.v2i2.345

Abstract

Tanaman kelor tumbuh di daerah tropis dan telah dikenal oleh masyarakat sebagai sayur dan berkhasiat sebagai obat tradisional. Sangat jarang ditemukan penelitian yang mengidentifikasi senyawa metabolit sekunder pada bagian akar kelor. Oleh karena itu, penelitian ini bertujuan untuk mengidentifikasi senyawa metabolit sekunder yang terkandung dalam akar kelor (Moringa oleifera L.) yang berasal dari Desa Talulobutu, Kabupaten Bone Bolango. Metode penelitian ini menggunakan reagen Mayer dan reagen Dragendorff untuk mengidentifikasi senyawa alkaloid, reagen NaOH 4% untuk mengidentifikasi senyawa tanin, reagen Pb(C2H3O2)2 10% untuk megidentifikasi senyawa flavonoid, dan uji buih menggunakan aquadest panas untuk megidentifikasi senyawa saponin.Moringa plant grows in the tropics and has been known by the public as a vegetable and efficacious as traditional medicine. It is very rare to find studies that identify secondary metabolites in the roots of Moringa. Therefore, this study aims to identify secondary metabolites contained in Moringa root ( Moringa oleifera L.) originating from Talulobutu Village, Bone Bolango Regency. This research method uses Mayer's reagent and Dragendorff's reagent to identify alkaloid compounds, 4% NaOH reagent to identify tannin compounds, Pb(C2H3O2)2  10% reagent to identify flavonoid compounds, and foam test using hot aquadest to identify  saponins compounds.
The effectiveness of butterfly pea hydrogel film (Clitoria Ternatea) with chitosan and poly-vinyl-alcohol based as diabetic wound healing Wicita, Prisca Safriani; Daud, Rizka Puji Astuti; Sapiun, Zulfiayu; Yahya, Cindy; Wantaa, Nurunnisa; Mohamad, Fihrina; Imran, Arlan K.; Hartati, Hartati; Husain, Fadli
JURNAL ILMU KEFARMASIAN INDONESIA Vol 22 No 2 (2024): JIFI
Publisher : Faculty of Pharmacy, Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35814/jifi.v22i2.1483

Abstract

Butterfly pea possesses antioxidant activities with IC50 470 μg/ml of wound healing acceleration quality. Hydrogel for diabetic wound healing due to its physical characteristic that binds water, aside from its qualities that wets the surface and bio-compatibility in the body. This study aimed to identify effectivity test of hydrogel film preparation with butterfly pea (clitoria ternatea l.) Water extract for diabetic wound healing, employing true experimental method which involves 12 rats divided into 4 groups. The control group was treated without the Hydrogel (HET) or HET0 on hyperglycemic rats, HET1 (2%), HET2 (5%), and HET3 (7.5%). The findings revealed wounds treated with HET0 was healed in 9 days with 11.13 mm of diameter (100%), HET1 was healed in 6 days with 15.22 mm of diameter (100%), HET2 that was healed in 4 days with 11.29 mm of diameter (100%), and HET3 that was healed in 8 days with 9.05 mm of diameter (100%). It was concluded that the effectivity test revealed that the best formula is HET2 (5%) healed in 4 days with 11.29 mm of diameter in 100%.
Co-Authors Basri, Insyira Fadliana Basri, Rakhmadhana Fitraeni Daud, Rizka Puji Astuti Denny Indra Setiawan Fadli Husain Fihrina Mohamad Fitriah Ayu Magfirah Yunus Fitriah Ayu Maghfirah Yunus Ghaitsa Zahira Sopha Yusuf Hartati Hartati Husain, Fadli Imran, Arlan K Insyira Fadliana Basri Nangsih Sulastri Slamet Pratiwi Ishak Pratiwi Y Ishak Putri, Nurwigya Mohamad Sapiun, Zulfiayu Vyani Kamba Wantaa, Nurunnisa Yahya, Cindy Ysrafil, Ysrafil Yunus, Fitriah Ayu Magfirah