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All Journal JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) JMM (Jurnal Masyarakat Mandiri) Journal of Health Policy and Management Abdimas Umtas : Jurnal Pengabdian kepada Masyarakat Jurnal Ilmu Kefarmasian Indonesia Science Midwifery Journal of Experimental and Clinical Pharmacy (JECP) Bakti Sekawan : Jurnal Pengabdian Masyarakat

Hartati Hartati

Poltekkes Kemenkes Gorontalo

Author-ID : 5391096

Religion Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Dentistry Education Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary Other

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KNOWLEDGE, ATTITUDE, AND IMPLEMENTATION OF COLD CHAIN MANAGEMENT IN BOALEMO DISTRICT, GORONTALO, INDONESIA Pangalo, Paulus; Sapiun, Zulfiayu; Ischak, Wenny Inno; Goi, Misrawatie; Hartati, Hartati
Journal of Health Policy and Management Vol 5, No 2 (2020)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (246.15 KB)

Background: Children's health is a priority in health development with the goal of reducing child mortality. So far, high immunization coverage does not guarantee the emergence of diseases that can be prevented by immunization (PD3I). Cold Chain Management is a system used to store vaccines in good condition which refers to the vaccine supply chain for the immunization procurement chain. The purpose of this study was to examine the relationship of knowledge, attitude, and implementation of cold chain management.Subjects and Method: This was a cross sectional study conducted at 11 health centers in Boalemo District, Gorontalo, Indonesia, in September 2018. A sample of 34 health officers was selected purposively. The dependent variable was cold chain management. The independent variables were knowledge and attitude. The data were collected by questionnaire and observation sheets. The data were analyzed by Chi square.Results: High knowledge increased positive attitude toward implementation of cold chain management (OR= 5.87; p= 0.061). High knowledge (OR= 2.17; p= 0.448) and positive attitude (OR= 2.69; p= 0.405) increased implementation of cold chain management, but they were statistically non-significant.Conclusion: High knowledge and positive attitude increase implementation of cold chain managementKeywords: cold chain management, vaccine, knowledge, attitudeCorrespondence: Zulfiayu Sapiun. Department of Pharmacy, Health Polytechnics, Ministry of Health Gorontalo.Jl. Taman Pendidikan 36, Gorontalo 96123, Indonesia. Email: zulfiayu@poltekkesorontalo.ac.id. Mobile: 081244521639Journal of Health Policy and Management (2020), 05(02): 139-145https://doi.org/10.26911/thejhpm.2020.05.02.06

Uji Aktivitas Antioksidan Sediaan Lip Balm Rambut Jagung (Zea mays L.) dengan Metode DPPH (1,1-Diphenyl-2-Picrylhydrazyl) Hartati Hartati; Fadli Husain; Nangsih Sulastri Slamet; Fihrina Mohamad; Zulfiayu Sapiun
JURNAL ILMU KEFARMASIAN INDONESIA Vol 18 No 2 (2020): JIFI
Publisher : Fakultas Farmasi Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35814/jifi.v18i2.829

Jagung sebagai komoditas utama di Provinsi Gorontalo menghasilkan limbah yang cukupbanyak. Hal ini membuat pemerintah menawarkan peluang investasi dengan memanfaatkan limbahjagung, di antaranya rambut jagung. Studi pustaka menunjukkan bahwa rambut jagung memilikiaktivitas antioksidan yang cukup baik, sehingga dilakukan formulasi lip balm dengan memanfaatkaninfusa rambut jagung sebagai bahan aktif. Penelitian kuantitatif dengan quasi eksperimen laboratoriumdilakukan untuk mengetahui aktivitas antioksidan dari sediaan lip balm rambut jagung (Zea mays L.)yang diformulasi dengan menggunakan tiga konsentrasi infusa rambut jagung, yaitu Formula A (7,5%);Formula B (15%) dan Formula C (22,5%). Sediaan dibuat dengan mencampurkan fase air (infusa rambutjagung dan gliseril monostearat) dengan fase minyak (lanolin, beeswax, setil alkohol, paraffi n cair danminyak jagung) serta emulgator (span 60 dan tween 60). Hasil uji stabilitas organoleptik dan pH selama4 minggu pengamatan menunjukkan bahwa tidak ada perubahan, baik dari segi organoleptik maupunpH masing-masing sediaan. Aktivitas antioksidan diukur dengan menggunakan spektrofotometer UVVisibel“SHIMADZU UV-1800” dan kuersetin (1000 μg/mL) sebagai pembanding. Hasil pengujianmenunjukkan bahwa Formula B (15%) memberikan aktivitas yang lebih baik dalam meredam radikalDPPH dengan nilai IC50 sebesar 0,987 mg/mL, Formula C (22,5%) sebesar 1,857 mg/mL dan FormulaA (7,5%) sebesar 2,909 mg/mL.

ANALISIS KEJADIAN MEDICATION ERROR PADA PASIEN ICU Hartati Hartati; Nike Herpianti Lolok; Achmad Fudholi; Satibi Satibi
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 4, No 2
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.277

Rumah Sakit Umum Daerah (RSUD) Kota Baubau dan RS Santa Anna Kendari sebagai rumah sakit rujukan di Sulawesi Tenggara terus berupaya untuk meningkatkan mutu pelayanan kesehatan, tetapi keterbatasan peralatan, sarana dan prasarana, serta sumber daya manusia menjadi kendala tersendiri. Di antaranya adalah belum terbentuknya tim patient safety dan masih diterapkannya sistem rawat gabung pada ruang Intensive Care Unit (ICU) yang berpotensi menimbulkan kejadian medication error. Tujuan penelitian ini adalah untuk mengetahui angka kejadian medication error pada pasien ICU di RSUD Kota Baubau dan RS Santa Anna Kendari serta faktor-faktor yang mempengaruhi kejadian medication error tersebut. Penelitian ini merupakan penelitian deskriptif dengan metode pengumpulan data berupa telaah resep dan observasi terhadap proses penyiapan hingga pemberian obat pada pasien ICU yang dilanjutkan dengan diskusi kelompok terarah bersama direktur rumah sakit, kepala instalasi farmasi, dan kepala ruang ICU. Analisis data dilakukan dengan mempresentasikan jumlah kejadian pada masing-masing kelompok indikator medication error. Hasil analisis menunjukan bahwa kejadian medication error terbesar pada pasien ICU RSUD Kota Baubau berupa administration error dengan 144 kejadian (46,91%), kemudian dispensing error dengan 119 kejadian (38,76%), dan kejadian terkecil adalah prescribing error dengan 44 kejadian (14,33%). Demikian pula pada pasien ICU di RS Santa Anna Kendari, angka kejadian medication error tertinggi berupa administration error, yaitu 81 kejadian (42,6%), diikuti prescribing error, yaitu 71 kejadian (37,4%), dan dispensing error, yaitu 38 kejadian (20%). Faktor-faktor yang turut mempengaruhi kejadian medication error adalah persoalan sistem (minimnya kelengkapan fasilitas di rumah sakit), profesional (sumber daya manusia, meliputi dokter, tenaga farmasis, serta perawat), dan dokumentasi. Kata kunci: Medication Error, Pasien ICU, Faktor-Faktor yang Mempengaruhi

Empowerment of Gorontalo Local Natural Ingredients to Become Functional Food at Dasa Wisma, South Toto Village, Kabila District, Towards A Resilient Village in The Middle of COVID-19 Hartati Hartati; Nangsih Sulastri Slamet; Arlan K. Imran; Salman Salman
ABDIMAS: Jurnal Pengabdian Masyarakat Vol. 5 No. 2 (2022): ABDIMAS UMTAS: Jurnal Pengabdian Kepada Masyarakat
Publisher : LPPM Universitas Muhammadiyah Tasikmalaya

COVID-19 is a global health problem, including in Indonesia. In addition to health problems, the increase in the number of cases of COVID-19 also has an impact on the global economy which affects stability in Indonesia. Based on the latest situation data on the development of COVID-19 cases released by the Task Force for the Acceleration of Handling COVID-19, Bone Bolango Regency, Gorontalo Province until December 31, 2020, Kabila District had the highest number of incidents, which had 122 positive confirmed cases of COVID-19. One of the 12 villages within the Kabila sub-district, South Toto Village had the highest incidence which had 38 cases. This community service aims to apply the results of research related to the use of natural materials such us Water Gourds(Lagenaria siceraria) which has antioxidant activity, so it can be used as an immunomodulator that can strengthen the body's resistance during the COVID-19 pandemic. The methods used were the distribution of Water Gourd juice syrup and training of cadres/community groups regarding the procedures for making Water Gourd juice syrup (Lagenaria siceraria). This is to increase the level of health and skills of the Gorontalo community in general and the awareness of cadres/community groups in the location where community service is carried out in particular. The parameters that can be measured in this community service are data from the pretest and posttest results which include questions related to public knowledge about COVID-19, Gorontalo local natural ingredients that are nutritious, knowledge in making functional drinks, as well as the rules and procedures for managing p-IRT for food processing businesses. Based on the results of data analysis, it was found that the average level of public knowledge increased from 58% to 72.4%.

Aktivitas Antimikroba Sabun Antiseptik Bunga Eceng Gondok (Eichhornia crassipes) dengan Basis Minyak Jelantah Nangsih Sulastri Slamet; Fihrina Mohamad; Hartati Hartati; Fadli Husain; Zulfiayu Sapiun
JURNAL ILMU KEFARMASIAN INDONESIA Vol 20 No 2 (2022): JIFI
Publisher : Fakultas Farmasi Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35814/jifi.v20i2.1078

Water hyacinth flowers (Eichhornia crassipes) contain antibacterial phenols, flavonoids, alkaloids, tannins, terpenoids, sterols, and glycosides that can be made into antiseptic soaps. Used cooking oil purifi ed with banana peel can be used to make soap. This study aimed to determine how to process used cooking oil, formulate and test antimicrobial antiseptic soaps using water hyacinth flower extract. The method uses antiseptic soap formulated with 10%, 15%, and 20% water hyacinth infusion. Physical, chemical, irritation, and antibacterial testing of the preparation. Used cooking oil is refined and clear, not thick. Water hyacinth flower extract can be formulated into antiseptic soap with a 1.5 cm foam height, cleaning power in criteria 3, pH in the range 9-10, water content >15%, and free alkali content of 0.6- 1.3%. Formula A (19.17 mm), B (20.01 mm), and C have strong antibacterial activity against E. coli based on the diameter of the barrier (20.13 mm). Water hyacinth flower extract and used cooking oil can be used to make antimicrobial antiseptic soap.

Analysis of prescribing error incidence in out-patient prescription at community health center of Tilamuta Boalemo Regency Sukmawati Damiti; Syamsul Thalib; Vyani Kamba; Ysrafil Ysrafil; Hartati Hartati
Science Midwifery Vol 10 No 5 (2022): December: Science Midwifery
Publisher : Institute of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/midwifery.v10i5.1060

Prescribing error can also be referred to as the error in medicine prescription that could endanger the patients. The absence of the right preparation dose can be potentially lead to misread by the transriber, as different medicines might have various preparation doses. The aimed of this study to identify the prescribing errors cases in patients in Tilamuta Community Health Center. The analysis on the prescription was conducted to identify the administrative and pharmaceutical completeness of the prescription. The data involved retrospective and prospective towards 300 prescriptions of out patients in Tilamuta Community Health Center by random sampling Method. The inclusion criteria employed out patient prescription for patients age 1-15 years old and 60 years old and above. The results showed that the highest percentage of prescribing error cases was in administrative error at 98,3% (295 prescription), while in the pharmaceutical error, the percentage arrived at 52,3% (157 prescription). This study was concluded that the highest prescribing error cases in Tilamuta community Health Center were the administrative error in the form of the absence of Occupational License at 96,7% or 293 prescriptions, while the pharmaceutical error at 37,3% or 112 prescriptions involved too low dosage.

Community Empowerment in Handling Non-Communicable Diseases Through Self-Medication and Use of Toga in Alale Village, Central Suwawa District, Bone Bolango Regency Hartati Hartati; Vyani Kamba; Insyira Fadliana Basri
ABDIMAS: Jurnal Pengabdian Masyarakat Vol. 6 No. 1 (2023): ABDIMAS UMTAS: Jurnal Pengabdian Kepada Masyarakat
Publisher : LPPM Universitas Muhammadiyah Tasikmalaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35568/abdimas.v6i1.2951

Self-medication is an effort in treatment that is carried out independently. Based on data from the Central Statistics Agency (BPS) for 2019 regarding health indicators for the Indonesian population, it is known that the data obtained on self-medication by Indonesian people from 2017 to 2019 for self-medication has increased from 71.46%. In Gorontalo Province, self-medication has been carried out by 76.60% of the population. Preliminary studies that have been carried out, many people in Alale Village, Suwawa Tengah District, buy drugs at the weekly market with the intention of self-medication, but there is still a lack of knowledge of proper self-medication and the use of natural plant materials as an alternative treatment. This community service aims to apply the results of research related to self-medication carried out by the community in increasing immunity during the current COVID-19 pandemic. The application is manifested in the form of CBIA (Community Based Interactive Method) in the form of counseling in the form of lectures, discussions, consultations, educational games as well as training assistance for cadres/community groups related to procedures for making traditional ingredients using plants in the surrounding environment. This is to increase knowledge and understand procedures for self-medication using conventional medicines and traditional medicines in the form of Family Medicinal Plants (TOGA) in dealing with non-communicable diseases, especially at the location of the community service implementation. Community service activities in Alale Village, Central Suwawa District, Bone Bolango Regency were carried out in 2 (two) stages, where stage I included a pretest prior to socialization, providing material and outreach about self-medication, providing drug information services, providing training on how to make simple traditional concoctions. Phase II includes monitoring of self-medication actions, mentoring and monitoring of making samples of Family Medicinal Plants (TOGA), and evaluation through posttest. The evaluation results obtained from the survey on community service activities show that the community's understanding has increased from 55.5% to 90%. This shows that community service activities have succeeded in increasing the understanding of the people of Alale Village.

Pemberdayaan Kelurahan Dulomo Selatan Melalui Pembuatan APD dan Peningkatan Sistem Imun Dengan Pemberian Multivitamin Pada Penderita PTM Dalam Menghadapi Pandemi Covid-19 Lusiane Adam; Ahmad Aswad; Ratnawati Ratnawati; Hartati Hartati
Bakti Sekawan : Jurnal Pengabdian Masyarakat Vol 2 No 2 (2022): Desember
Publisher : Puslitbang Sekawan Institute Nusa Tenggara

Covid-19 is an infectious disease caused by a newly discovered type of coronavirus, which spreads very quickly, can attack anyone regardless of age or gender and is more at risk of attacking people with certain medical conditions including sufferers of chronic Non-Communicable Diseases (PTM). The minimum and high cost of PPE, and the high number of PTM sufferers can be at risk of contracting this disease from other people. The purpose of this community service is to empower the community through making PPE to prevent the spread of the Covid-19 virus in the Dulomo Selatan Village community which is the location of the community service. Dulomo Village was chosen as the location for community service because it is one of the working areas of the North City Health Center which has the highest number of elderly people and has the highest number of sufferers of Non-Communicable Diseases. The procedure for the activity is first licensing, coordinating with Dulomo Selatan Village and North City Health Center, preparing tools, health promotion media, and places used for program implementation. This activity consisted of measuring the knowledge of Dulomo Selatan village cadres through distributing questionnaires, counselling about Covid-19, socializing on making simple and fulfilling PPE (masks and face shields), distributing multivitamins for PTM sufferers, and distributing stimulants in the form of masks and hand sanitizers. The results of this community service activity showed that there was an increase in cadres' knowledge about COVID 19, government policies, clean and healthy living behaviour’s and the correct way to use PPE, as well as meeting the needs of PPE in the Dulomo Selatan Village community and especially PTM sufferers in the Dulomo Selatan Village area

Analisis Kemoterapi pada Pasien Tn. “AM” dengan Acute Lymphoblastic Leukaemia (ALL) disertai HIV Positif dan Hepatitis B Hartati, Hartati
Journal of Experimental and Clinical Pharmacy (JECP) Vol 3, No 2 (2023): August 2023
Publisher : Poltekkes Kemenkes Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52365/jecp.v3i2.617

Leukemia Limfoblastik Akut (ALL/LLA) adalah proliferasi ganas sel limfoid yang tersumbat pada tahap awal diferensiasi yang dapat menyerang sumsum tulang, darah, dan situs ekstrameduler. Penatalaksanaan leukemia meliputi terapi kuratif dan suportif. Studi kasus ini bertujuan untuk memperoleh gambaran tentang regimen kemoterapi pasien ALL yang disertai Hepatitis B Kronik dan HIV positif. Pengumpulan data menggunakan desain deskriptif dengan metode wawancara serta observasi langsung kondisi pasien dan e-rekam medik, e-resep yang dikaji kesesuaiannya berdasarkan protokol kemoterapi. Berdasarkan sequencing regimen kemoterapi diperoleh bahwa pasien menerima regimen Hyper CVAD dengan nilotinib, dimana penilaian resiko Chemotherapy Induced Nausea Vomiting diperoleh bahwa protokol kemoterapi yang diterima termasuk dalam kategori Moderate Emetogenic. Regimen ini juga disertai dengan pemberian Methotrexate dosis tinggi sebagai profilaksis CNS. Akan tetapi, untuk mengurangi resiko nefrotoksisitas akibat pemberian Methotrexate dosis tinggi, maka diperlukan tambahan natrium bikarbonat dan allopurinol untuk mencegah TLS pada pasien dengan ALL.Acute Lymphoblastic Leukaemia (ALL) is a malignant proliferation of lymphoid cells that are occlude at an early stage of differentiation and can invade the bone marrow, blood, and extramedullary sites. Management of leukemia includes curative and supportive therapy. This case study aims to obtain an overview of the chemotherapy regimen of ALL patients with chronic hepatitis B and HIV. Data were collected in a descriptive design with interview methods and direct observation of patient conditions and e-medical records. E-prescriptions were reviewed for suitability based on chemotherapy protocols. Based on the chemotherapy regimen sequencing, it was found that the patient received the hyper-CVAD regimen with nilotinib, while the chemotherapy-induced nausea and Vomiting risk assessment found that the chemotherapy protocol received was included in the Moderate Emetogenic category. This regimen is also accompanied by the administration of high doses of Methotrexate as CNS prophylaxis. However, to reduce the risk of nephrotoxicity due to the administration of high doses of Methotrexate, it is necessary to add sodium bicarbonate and allopurinol to prevent TLS in patients with ALL.

Efek Ekstrak Etanol 70% Herba Akar Kucing (Acalypha indica L.) dalam Menurunkan Kadar Gula Darah Mencit (Mus musculus) Jantan yang diinduksi Aloksan Nihe, Nur Fauziyah S.; Hartati, Hartati; Nur, Moh. Usman; Husain, Fadli
Journal of Experimental and Clinical Pharmacy (JECP) Vol 4, No 1 (2024): February 2024
Publisher : Poltekkes Kemenkes Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52365/jecp.v4i1.914

Tanaman akar kucing (Acalypha indica L.) merupakan tanaman yang biasanya digunakan oleh masyarakat untuk mengatasi penyakit diabetes. Tanaman ini memiliki kandungan senyawa flavonoid dan alkaloid yang diduga memiliki efek terhadap penurunan kadar glukosa darah. Penelitian ini bertujuan untuk mengetahui konsentrasi ekstrak etanol herba akar kucing yang efektif dalam menurunkan kadar gula darah pada mencit (Mus musculus) jantan setelah diinduksi aloksan. Penelitian ini merupakan penelitian berjenis eksperimental laboratorium dengan kelompok perlakuan dosis yang berbeda yaitu F1 (5 mg), F2 (10 mg), dan F3 (15 mg) dan sebagai kontrol positif (K+) digunakan obat glibenklamid dan dilakukan pengukuran kadar gula darah menggunakan glukometer terhadap mencit jantan. Hasil penelitian menunjukkan penurunan kadar gula darah terjadi pada mencit yang telah diberikan ekstrak etanol herba akar kucing setelah 7 hari pengamatan dengan selisih penurunan yaitu F1 41 mg/dl (33,06%), F2 57 mg/dl (45,72%), F3 64 mg/dl (57,06%). Hasil uji One Way Anova menggunakan SPSS 25.0 menunjukkan bahwa terdapat perbedaan yang signifikan diantara 4 perlakuan tersebut dengan control positif. Kesimpulannnya bahwa semua konsentrasi ekstrak etanol herba akar kucing memiliki kemampuan dalam menurunkan kadar gula darah pada mencit dengan konsentrasi yang paling efektif adalah kelompok F3 15 mg (57,06%).The Acalypha indica L. is a plant that is usually used by people to treat diabetes. This plant contains flavonoid and alkaloid compounds, which are thought to have an effect on reducing blood glucose levels. This study aims to determine the concentration of the ethanol extract of the Acalypha indica herb that is effective in reducing blood sugar levels in male mice (Mus musculus) after being induced by alloxan. This research is a laboratory experimental type study with different dose treatment groups, namely F1 (5 mg), F2 (10 mg), and F3 (15 mg), and as a positive control (K+), the drug glibenclamide was used, and blood sugar levels were measured using a glucometer against male mice. The results showed that a decrease in blood sugar levels occurred in mice that had been given an ethanol extract of Acalypha indica herb after 7 days of observation, with a difference in the decrease, namely F1 41 mg/dl (33.06%), F2 57 mg/dl (45.72%), and F3 64 mg/dl (57.06%). The results of the one-way ANOVA test using SPSS 25.0 showed that there were significant differences between the four treatments and the positive control. The conclusion was that all concentrations of Acalypha indica herb ethanol extract had the ability to reduce blood sugar levels in mice, with the most effective concentration being the F3 15 mg group (57.06%).

Co-Authors Achmad Fudholi Adam, Lusiane Ahmad Aswad Daud, Rizka Puji Astuti Fadli Husain Fihrina Mohamad Husain, Fadli Imran, Arlan K Insyira Fadliana Basri Ischak, Wenny Inno MISRAWATIE GOI Mohamad Usman Nur Nangsih Sulastri Slamet Nihe, Nur Fauziyah S. Nike Herpianti Lolok Nur, Moh. Usman Pangalo, Paulus PRISCA SAFRIANI WICITA Ratnawati Ratnawati Salman Salman Sapiun, Zulfiayu Satibi Satibi Sukmawati Damiti Syamsul Thalib Vyani Kamba Wantaa, Nurunnisa Yahya, Cindy Ysrafil, Ysrafil

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