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All Journal Althea Medical Journal Jurnal Ilmiah Multidisiplin Indonesia Plexus Medical Journal
Aisyah Amanda Hanif
Faculty Of Medicine, Universitas Padjadjaran, Jalan Raya Bandung-Sumedang Km.21, Jatinangor, Sumedang, Indonesia,
Agriculture, Biological Sciences & Forestry Computer Science & IT Earth & Planetary Sciences Engineering Health Professions Medicine & Pharmacology Physics Public Health

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Factors Influencing the Success Rate of Cardiopulmonary Resuscitation Hanif, Aisyah Amanda; Rachman, Iwan Abdul; Yuwono, Hendro Sudjono
Althea Medical Journal Vol 2, No 4 (2015)
Publisher : Althea Medical Journal

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (553.013 KB)

Abstract

Background: Cardiopulmonary resuscitation (CPR) is a series of actions performed on cardiac arrest patients. Not all patients receiving CPR can survive. The outcome of CPR is influenced by several factors. This study was conducted to determine the success rate of CPR and the factors influencing it in Dr. Hasan Sadikin General Hospital in 2013.Methods: This study was conducted by using 168 patient medical records who underwent CPR and met the inclusion criteria in the Resuscitation Room of Dr. Hasan Sadikin General Hospital from January to December 2013. The collected data consisted of age, gender, pre-arrest diagnosis, initial rhythm, response time and clinical outcome of CPR. The results were expressed in frequencies and percentage. The data were analyzed using the chi-square test.Results: The Success rate of CPR was 15.5%. The success rate was higher in patients with cardiac prearrest diagnoses (8.33%, p=0.024). The most common initial rhythm was unshockable rhythms (83.92%), yet patients with shockable heart rhythms had higher success rates (40.74%, p<0.001). All of the surviving patients had response time within the first minute from cardiac arrest.Conclusions: Success rate of CPR in the resuscitation room of Dr. Hasan Sadikin General Hospital during 2013 is still low. The factors influencing the survival rate are the pre-arrest diagnosis and initial heartrhythm. [AMJ.2015;2(4):615–9] DOI: 10.15850/amj.v2n4.657
Factors Influencing the Success Rate of Cardiopulmonary Resuscitation Aisyah Amanda Hanif; Iwan Abdul Rachman; Hendro Sudjono Yuwono
Althea Medical Journal Vol 2, No 4 (2015)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (553.013 KB)

Abstract

Background: Cardiopulmonary resuscitation (CPR) is a series of actions performed on cardiac arrest patients. Not all patients receiving CPR can survive. The outcome of CPR is influenced by several factors. This study was conducted to determine the success rate of CPR and the factors influencing it in Dr. Hasan Sadikin General Hospital in 2013.Methods: This study was conducted by using 168 patient medical records who underwent CPR and met the inclusion criteria in the Resuscitation Room of Dr. Hasan Sadikin General Hospital from January to December 2013. The collected data consisted of age, gender, pre-arrest diagnosis, initial rhythm, response time and clinical outcome of CPR. The results were expressed in frequencies and percentage. The data were analyzed using the chi-square test.Results: The Success rate of CPR was 15.5%. The success rate was higher in patients with cardiac prearrest diagnoses (8.33%, p=0.024). The most common initial rhythm was unshockable rhythms (83.92%), yet patients with shockable heart rhythms had higher success rates (40.74%, p<0.001). All of the surviving patients had response time within the first minute from cardiac arrest.Conclusions: Success rate of CPR in the resuscitation room of Dr. Hasan Sadikin General Hospital during 2013 is still low. The factors influencing the survival rate are the pre-arrest diagnosis and initial heartrhythm. [AMJ.2015;2(4):615–9] DOI: 10.15850/amj.v2n4.657
Efek Asam Klorogenat pada Ekspresi Mrna IL-6 dan CD86 Lobus Frontal Tikus Model Diabetes Mellitus Munawaroh, Fauziyatul; Hanif , Aisyah Amanda; Ragil Kemuning, Asri; Mutmainah, Iffa; Rachmawati, Yenny; Muharam Nurdin, Naufal
Plexus Medical Journal Vol. 3 No. 4 (2024): Agustus
Publisher : Fakultas Kedokteran, Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/plexus.v3i4.1815

Abstract

Pendahuluan: Diabetes Mellitus (DM) merupakan penyakit kronik dengan berbagai komplikasi, salah satunya yaitu Encephalopati Diabetikum (ED). Hiperglikemia pada DM akan mengakibatkan neuroinflamasi melalui jalur M1 proinflamatorik. Beberapa agen proinflamatori akan meningkat dengan aktifnya jalur ini, seperti IL-6. Neuroglia kemudian teraktivasi dan mengekspresikan CD86 pada membran sel. Asam klorogenat (CGA) merupakan senyawa polyphenol pada kopi  yang  memiliki  efek antiinflamasi.  Tujuan penelitian ini adalah untuk memperjelas efek CGA pada aktivasi mikroglia jalur M1 dengan melihat ekspresi mRNA IL-6 dan CD86 pada lobus frontal tikus dengan model DM. Metode: 24 ekor tikus jantan secara acak dibagi menjadi enam kelompok yaitu :  kontrol,   DM 1,5 bulan dan DM 2 bulan,  dan kelompok dengan pemberian  CGA dengan  tiga  dosis  berbeda  (CGA1,  CGA2,  CGA3).  Jaringan lobus frontal diambil untuk analisa ekspresi mRNA IL-6 dan CD86 menggunakan RT-PCR. Hasil: Ekspresi mRNA IL-6 lobus frontal berbeda signifikan antara kelompok kontrol dengan DM1,5 (p=0.010); kontrol dengan DM2 (p=0.001); kelompok DM2 dengan CGA2 (p=0.028). Ekspresi mRNA CD86 lobus frontal trdapat perbedaan signifikan antara kelompok kontrol dengan semua kelompok DM, baik dengan CGA atau tanpa CGA (p<0.05). Kelompok DM2 berbeda signifikan dengan kelompok CGA2 (p=0.000) dan kelompok CGA3 (p=0,000). Kesimpulan: Ekspresi mRNA penanda jaras proinflamatorik M1 (IL-6 dan CD86) pada neuroinflamasi lobus frontal akibat DM lebih rendah setelah pemberian CGA dengan dosis 25 mg/KgBB.
Radiological, Clinical, and Microbiological Manifestations of Pulmonary Tuberculosis Patients of a Secondary Hospital in Indonesia Rusmajati, Jetty; Hanif, Aisyah Amanda; Desdiani, Desdiani
Jurnal Ilmiah Multidisiplin Indonesia (JIM-ID) Vol. 4 No. 8 (2025): Jurnal Ilmiah Multidisplin Indonesia (JIM-ID) 2025
Publisher : Sean Institute

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Abstract

Tuberculosis (TB) remains a significant public health burden in Indonesia. Characterizing pulmonary TB's clinical, radiological, and microbiological features is vital to support timely and accurate diagnosis at secondary healthcare levels. This study aimed to analyze the clinical characteristics, radiological patterns, and microbiological status of pulmonary TB patients treated in secondary hospitals in Indonesia. This descriptive cross-sectional study retrospectively reviewed medical records of 58 adult patients with radiologically confirmed pulmonary TB, treated between January 2022 and December 2023. Data on demographics, symptoms, comorbidities, radiological features, and sputum smear results were analyzed. Associations between variables were tested using chi-square tests. Most patients were male (55.2%), with a mean age of 50.6 years. Previous TB history was recorded in 25.9% of cases, and 15.5% had comorbidities such as hypertension and diabetes. Cough (84.5%), fever (48.3%), and weight loss (41.4%) were the most common symptoms. Consolidation (89.7%) was the predominant radiological finding, often involving multiple lung zones (70.7%), with advanced lesions present in 77.6% of patients. Sputum smears were positive in 39.7% of cases. Pulmonary TB patients treated at secondary hospitals commonly present with advanced radiological lesions, significant comorbidities, and frequent smear-negative results. Strengthening radiological diagnostic capacity and integrated management of TB–diabetes comorbidity are essential to improve case detection and outcomes.
Co-Authors Asri Ragil Kemuning Desdiani, Desdiani Hendro Sudjono Yuwono Iffa Mutmainah Iwan Abdul Rachman Munawaroh, Fauziyatul Naufal Muharam Nurdin Rachmawati, Yenny Rusmajati, Jetty