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All Journal Jurnal SainHealth Jumat Ekonomi: Jurnal Pengabdian Masyarakat
Titik Sundari
Universitas Maarif Hasyim Latif
Biochemistry, Genetics & Molecular Biology Chemistry Economics, Econometrics & Finance Education Immunology & microbiology Medicine & Pharmacology Social Sciences Other

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COMPARISON OF LEUKOCYTE COUNT AND TYPES, NEUTROPHIL-TO-LYMPHOCYTE RATIO (NLR), AND PLATELET-TO-LYMPHOCYTE RATIO (PLR) IN NORMAL PREGNANT WOMEN AND THOSE WITH PREECLAMPSIA: PERBANDINGAN JUMLAH DAN JENIS LEUKOSIT, NEUTROFIL LIMFOSIT RATIO (NLR), PLATELET LIMFOSIT RATIO (PLR) PADA IBU HAMIL NORMAL DAN PREEKLAMPSIA Trisilia Taufik Putri; Martha Indah Widiyaningtiyas; Titik Sundari; Dheasy Herawati
Jurnal SainHealth Vol. 10 No. 2 (2026): September 2026
Publisher : Faculty of Health Sciences Universitas Maarif Hasyim Latif

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51804/jsh.v10i2.17476.139-153

Abstract

Preeclampsia is a serious problem that can occur during pregnancy, usually after 20 weeks. This condition involves high blood pressure and protein in the urine. The number of leukocytes, especially neutrophils, is significantly higher in severe preeclampsia compared to normotensive pregnancies. The Neutrofil Limfosit Ratio plays a role in identifying inflammation and tumor immunology and has been shown to influence the prognosis of chronic and acute inflammatory conditions. The Platelet Limfosit Ratio may be using to assess an progression of the condition and whether it is worsening or whether infection or inflammation is occurring. The purpose of this research were to compare the number and type of leukocytes, NLR, and PLR in normal and preeclamptic pregnant women at the Mega Medika Clinic in Kampungbaru, Nganjuk. This research were an cross-sectional studies with 30 normal and preeclamptic pregnant women each who met the inclusion and exclusion criteria. The variables in this research was the number and type of leukocytes, NLR values, and PLR values. The results of the Mann-Whitney test showed that there were significant differences in the number of leukocytes, eosinophils, stab neutrophils (p = 0.000), segmented neutrophils (p = 0.035), lymphocytes (p = 0.008), monocytes (p = 0.015), and NLR (p = 0.017) between normal and preeclamptic pregnant women (p <0.05). Meanwhile, there were no significant differences in basophils (p = 0.082) and PLR (p = 0.395; p> 0.05). The conclusion is that the number of leukocytes, NLR values & types of leukocytes (eosinophils, stab neutrophils, segmented neutrophils & lymphocytes) are different between normal and preeclamptic pregnant women. While PLR values & types of leukocytes (basophils) are not different between normal and preeclamptic pregnant women.
Co-Authors Adinda Dika Infantria Afisa Asmaanis Andita Ayu Mandasari Dendi Rinaldi Dheasy Herawati Esti Rizkiana Pratiwi Evi Dwi Aprilia Suryani Faikotuljannah Faikotuljannah Frida Luthfia Mari Halik Wijaya Indra Adi Wira Prasetya Ismiatus Salamah Jhoni Pramanda Tubulau Khoirul Ngibad Martha Indah Widiyaningtiyas Moch Lazuardi Imani Muhammad Sungging Pradana Nilam Maghfiroh Novi Ersanto Putri Alifia Arofah Risma Wanda Putri Siti Nur Husnul Yusmiati Siti Nur Husnul Yusmiati Sulthan Al Akbar Trisilia Taufik Putri Wahyu Adi Setiawan