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All Journal PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) Jurnal Kesmas Asclepius Jurnal Farmasi dan Sains Indonesia (JFSI) Jurnal Abdimas Bina Bangsa Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Lentera Negeri Sinteza Journal of Pharmaceutical and Sciences.
Fitriwati Sovia
Hamzanwadi University
Religion Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Education Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Other

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Combination of Traditional Medicine and Synthesis Medicine Therapy for Hypertension and Diabetic Patients Ersi Arviana Ihsan; Fitriwati Sovia; Erma Ewisa Oktresia; Tri Puspita Yuliana; Sulistia Ardyati; Arief Rafsanjani
PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) Jurnal Pharmacy, Vol. 18 No. 01 Juli 2021
Publisher : Pharmacy Faculty, Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/pharmacy.v18i1.9348

Abstract

Hypertension and diabetic are interrelated diseases affect atherosclerosis. This study aims to analyze the combination of traditional medicines and synthetic medicine with a job background for patients with hypertension and diabetic. Case-control study method retrieves patient data with medical records. Sampling was done with a purposive sampling technique of 30 respondents conducted in March-June at Labuhan Lombok Health Center. The results showed the percentage of diabetic patients was 26.67% for men and 73.33% for women with a background of 60% of traders, 20% of farmers, 13.3% of fishermen, and housewives of 6.7%. Furthermore, for hypertension patients, the percentage was 13.33% for men and 86.67% for women with a background of 40% of traders, 53.3% for farmers, 6.7% for fishermen. For traditional medicine used are Moringa oleifera L., Cucumis sativus L., jamu gendong, Averrhoa bilimbi L., Curcuma longa L., and Artocarpus camansi Blanco. Based on this, the risk factors for women are more generous than for men, and the use of a combination of drugs gives positive results in improving health.
Peran Kader Posyandu terhadap Tingkat Kunjungan Masyarakat Hartini Haritani; Puspawan Hariadi; Ewisa Oktresia; Fitriwati Sovia; Baiq Maylinda Gemantari
Jurnal Kesmas Asclepius Vol 4 No 2 (2022): Jurnal Kesmas Asclepius
Publisher : Institut Penelitian Matematika, Komputer, Keperawatan, Pendidikan dan Ekonomi (IPM2KPE)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31539/jka.v4i2.4456

Abstract

This study aims to describe the role of posyandu cadres on the level of visits by the users. The method used in this study is descriptive qualitative with a program evaluation approach. The results obtained from this study are that the number of visits by pregnant women, toddlers, and the elderly has increased. However, a strategy is needed to increase the interest of young women to utilize posyandu so that they can increase the number of visits by adolescents. In conclusion, the role of Posyandu cadres dramatically contributes to the health needs of small communities, especially in villages. Keywords: Cadres, Posyandu, Healthy
Tingkat kunjungan masyarakat pada pelayanan posyandu keluarga di desa Toya, Nusa Tenggara Timur Hartini Haritani; Sulistia Ardyati; Erma Ewisa Oktresia; Fitriwati Sovia; Muhammad Zainul Majdi; Atiaturrahmaniah Atiaturrahmaniah; Baiq Aryani Novianti
Lentera Negeri Vol 3, No 1 (2022): Lentera Negeri
Publisher : Indonesian Institute For Counseling, Education and Therapy

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29210/99360

Abstract

Posyandu cadres are the driving force for the implementation of family posyandu services, both in moving targets, services and reporting. With the changing level of posyandu to a family type of this system increases the workload of posyandu cadres, the competence and skills of cadres need to be improved through training and mentoring. The data obtained was qualitative data with descriptive analysis method.  Data collection was carried out by conducting observations, interviews and technical training to posyandu cadres with the aim of providing knowledge about family posyandu services, and basic skills at tables 1 to table 8 for cadres so that the presence of this small group of people could increase the number of targeted visits to posyandu.  The results obtained from this activity were: the number of visits by pregnant women, toddlers and the elderly had increased. However, the strategy was needed to increase youth's interest in posyandu according to the number of visits by teenagers.
DETERMINASI KEPATUHAN MINUM OBAT PADA PASIEN DIABETES MELLITUS TIPE II DI PUSKESMAS TERARA: ANALISIS KORELASI FAKTOR-FAKTOR PENGARUH Sovia, Fitriwati; Anjani, Rizky Puji; Ramadhan, Leny
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 9 No 2 (2024): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jiis.v9i2.2115

Abstract

Diabetes mellitus is a chronic disease that requires ongoing management because it cannot be permanently cured. Adherence to the treatment plan is crucial to prevent deterioration in physical condition. This study aims to analyze the correlation between factors affecting medication adherence in patients with type II diabetes mellitus at Terara Community Health Center. This research uses an observational analytic design with a cross-sectional approach. The study population consists of 151 patients with type II diabetes mellitus, with a sample of 35 individuals selected through purposive sampling. Data were collected using a questionnaire and analyzed with Fisher's test. The results indicate that factors such as gender (P=0.015), occupation (P=0.015), knowledge (P=0.006), attitude (P=0.001), motivation (P=0.021), and family support (P=0.004) have a significant correlation with medication adherence. Conversely, age, education, and healthcare support did not show a significant correlation with medication adherence. In conclusion, factors such as gender, occupation, knowledge, attitude, motivation, and family support significantly influence medication adherence in patients with type II diabetes mellitus at Terara Community Health Center.
PENINGKATAN PENGETAHUAN MASYARAKAT MELALUI EDUKASI: PATUHI, OBATI DAN KENDALIKAN DIABETES Hariadi, Puspawan; Oktresia, Erma Ewisa; Sovia, Fitriwati; Gemantari, Baiq Maylinda
Jurnal Abdimas Bina Bangsa Vol. 6 No. 1 (2025): Jurnal Abdimas Bina Bangsa
Publisher : LPPM Universitas Bina Bangsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46306/jabb.v6i1.1703

Abstract

Diabetes Mellitus (DM) can lead to various complications, both macrovascular and microvascular. Diabetes education interventions play a crucial role in DM management, as they help improve patients' knowledge and adherence to diabetes management strategies. This study involved three sessions: a pre-test, an educational session, and a post-test. Among 53 respondents, the proportion of participants with a high level of knowledge increased from 30 (56.6%) to 43 (81.1%). Meanwhile, those with a low level of knowledge decreased from 10 (18.9%) to 1 (1.9%). This increase in knowledge levels demonstrates the effectiveness of the education provided. The average pre-test knowledge score was 69.06, compared to a post-test score of 86.23, demonstrating a significant improvement. Wilcoxon test analysis showed a significance value of <0.05. Thus, the "Patuhi, Obati dan Kendalikan Diabetes" education program for participants of the Chronic Disease Management Program (Prolanis) significantly enhanced participants' knowledge levels.
Identifikasi Interaksi Obat Pada Pasien Lansia Yang Berisiko Sindrom Metabolik Di Puskesmas Aikmel Sovia, Fitriwati; Hardiyanti, Novi; Rafsanjani, Arief; Oktresia, Erma Ewisa
Jurnal Farmasi & Sains Indonesia Vol 6 No 1 (2023)
Publisher : LPPM Sekolah Tinggi Ilmu Farmasi Nusaputera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52216/jfsi.vol6no1p39-46

Abstract

Metabolic syndrome is an increasingly prevalent health problem in both developed and developing countries, including Indonesia. The treatment of metabolic syndrome often involves polypharmacy, which increases the potential for drug interactions. Drug interactions are considered clinically important if they can cause increased toxicity or reduce the therapeutic effects of drugs, leading to a failure to achieve the desired therapeutic effect. Reported cases of drug interactions are more common in elderly patients. This study aims to determine the potential Drug-drug Interactions (DDIs) in elderly patients at risk of metabolic syndrome at Puskesmas Aikmel. The study uses a descriptive observational method with prospective data collection. The population in this study consists of outpatient patients at Puskesmas Aikmel from May to July 2021, meeting the inclusion criteria: patients diagnosed at risk of metabolic syndrome, elderly patients (age ? 60 years), and using a minimum of 2 drugs. Sampling was done using total sampling technique. The results of the study indicate 99 cases of potential drug interactions identified in the prescription of elderly patients. The drug classes with potential interactions include antihypertensive drugs in 51 (51.51%) cases, antihyperglycemic drugs in 42 (42.42%) cases, and dyslipidemia drugs in 6 (6.06%) cases. The types of drug interactions observed were pharmacokinetic interactions in 37 (37.37%) cases, pharmacodynamic interactions in 58 (58.58%) cases, and unknown interactions in 4 (4.04%) cases. The severity of these potential interactions was classified as minor in 5 (5.05%) cases, moderate in 86 (86.87%) cases, and major in 8 (8.08%) cases.
Uji Efektivitas Ekstrak Daun Renggak (Amomum dealbatum Roxb.) Sebagai Antihiperurisemia Pada Mencit Sovia, Fitriwati; Al-Adawiyah , Rosita; Yuliana , Tri Puspita
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 2 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i2.747

Abstract

Background: Hyperuricemia, resulting from excessive uric acid levels, can trigger chronic inflammation and increase the risk of gout. Conventional therapies such as allopurinol are associated with adverse effects, highlighting the need for natural alternatives. Renggak leaves (Amomum dealbatum Roxb.), an endemic plant from Lombok rich in flavonoids, have potential as xanthine oxidase inhibitors but remain underexplored. Objective: To evaluate the antihyperuricemic effect of renggak leaf extract in male white mice, determine the optimal dosage, and compare its efficacy with allopurinol. Methods: This study employed a pretest-posttest control group design. Hyperuricemia was induced using chicken liver juice administered for 14 days. The animals were divided into five groups: negative control (1% CMC-Na), positive control (allopurinol 10 mg/kg BW), and three extract-treated groups (50, 250, and 500 mg/kg BW), which received the extract for 21 days. Results: All extract doses significantly reduced uric acid levels (P < 0.05). The 500 mg/kg BW dose was the most effective (44.54% reduction), showing no significant difference compared to allopurinol (48.52%; p = 0.490). The effect is presumed to occur through xanthine oxidase inhibition by flavonoids. Conclusion: Renggak leaf extract, particularly at a dose of 500 mg/kgBW, shows potential as an alternative therapy for hyperuricemia with efficacy comparable to allopurinol. However, further studies such as toxicity tests, pharmacokinetic evaluations, and clinical trials are needed to validate its broader application.
Efektivitas Infusa Daun Jarak Kepyar (Ricinus communis L.) terhadap Kadar Kolesterol Total dan HDL Serum Darah Tikus Galur Wistar Hikmah, Rani Anggraini; Hariadi, Puspawan; Sovia, Fitriwati
Sinteza Vol. 2 No. 1 (2022): February
Publisher : Universitas Hamzanwadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (175.569 KB) | DOI: 10.29408/sinteza.v2i1.4367

Abstract

Jarak  kepyar (Ricinus communis L.) adalah salah satu tanaman herbal yang mengandung flavonoid khususnya kuersetin, tanin, dan saponin dimana senyawa-senyawa ini dipercaya dapat memberikan efek antihiperlipidemia. Tujuan dari penelitian ini untuk mengetahui efektivitas infusa dan untuk mendapatkan konsentrasi infusa daun jarak kepyar yang paling efektif sebagai antihiperlipidemia pada tikus galur wistar. Penelitian ini merupakan jenis penelitian true exsperimental dengan rancangan pretest-postest kelompok. Hewan uji terbagi menjadi 5 kelompok yaitu kontrol positif (simvastatin), kontrol negatif dan perlakuan (infusa daun jarak kepyar) dengan konsentrasi 10%, 20% dan 30%  dengan masing-masing kelompok sebanyak 5 ekor. Sebelum perlakuan hewan uji diberikan induksi kuning telur selama 25 hari kemudian diukur kadar kolesterol total, trigliserida, dan HDL. Pengukuran dilakukan sebelum dan sesudah induksi kuning telur kemudian dilakukan kembali setelah infusa daun jarak kepyar diberikan. Parameter yang diukur adalah kadar kolesterol total, trigliserida dan HDL. Berdasarkan hasil pengukuran kadar setelah pemberian infusa daun jarak kepyar diperoleh hasil persentasi penurunan kolesterol total yaitu kontrol negatif (8.43%), kontrol positif (15.28%), konsentrasi 10% (10.23%), konsentrasi 20% (20.03%), dan kelompok konsentrasi 30% (27.13%) dan peningkatan  HDL yaitu kelompok kontrol negatif (1.23%), kontrol positif (9.23%), konsentrasi 10% (2.96%), konsentrasi 20% (7.85%), dan kelompok konsentrasi 30% (5.14%).  Konsentrasi 20% dan 30% memberikan penururunan kadar kolesterol total secara signifikan (p<0.05)  dan peningkatan kadar HDL secara signifikan (p<0.05) oleh kontrol 20% jika dibandingkan dengan kontrol negatif. Infusa daun jarak kepyar (Ricinus communis L.) konsentrasi 30% paling efektif menurunkan kadar kolesterol total dan trigliserida, sedangkan yang paling efektif untuk meningkatkan kadar HDL  adalah konsentrasi 20%.
Gambaran Tingkat Kepuasan Pasien terhadap Pelayanan Informasi Obat di Apotek Wilayah Lombok Timur Hartono, M. Herry; Oktresia, Erma Ewisa; Sovia, Fitriwati
Sinteza Vol. 3 No. 2 (2023): August
Publisher : Universitas Hamzanwadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29408/sinteza.v3i2.18969

Abstract

Pharmaceutical services are a direct and responsible service to patients. One of the pharmaceutical service activities that align with the concept of pharmaceutical care is found in the quality of Drug Information Services (PIO) in pharmacies. The aim of this research is to determine the implementation of DIS based on the Indonesian Minister of Health Regulation No.73 of 2016 in pharmacies in the East Lombok region. This study is observational descriptive using quantitative analysis in the form of calculating the percentage of Respondent Achievement Level (TCR). Data was collected using a questionnaire covering eight activities that pharmacists should undertake when providing drug information, which were subsequently used as indicators. Sample selection was done through purposive sampling with a minimum of 96 samples. Based on the research results, the TCR percentage values for the indicators were as follows: information on drug efficacy at 78% with a good category; dosage form at 78% with a good category; usage instructions at 75% with a good category; drug dosage at 74% with a good category; side effects at 74% with a good category; drug storage at 74% with a good category; safety for pregnant and nursing mothers at 46% with a fair category; information on drug prices obtained a score of 90% with a very good category. The average TCR score for the 8 indicators was 73.3% with a good category in providing drug information services in accordance with the Indonesian Minister of Health Regulation No.73 of 2016 in pharmacies in the East Lombok region.
Analisis Efektivitas Biaya Penggunaan Insulin Lantus dan Apidra di RSUD Dr. R. Soedjono Selong Oktresia, Erma Ewisa; Sovia, Fitriwati; Ramadhan, Leny; Ramadani, Lalu Khilal
Sinteza Vol. 4 No. 2 (2024): August
Publisher : Universitas Hamzanwadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29408/sinteza.v4i2.26475

Abstract

Indonesia is one of the countries with the highest number of type II diabetes mellitus patients in the world, reaching 10.7 million people. Diabetes mellitus requires long-term treatment to control patients' blood glucose levels. The types of therapy used vary, leading to differences in costs and treatment outcomes. The use of insulin is a significant issue in diabetes mellitus therapy, especially at RSUD Dr. R. Soedjono, concerning its cost-effectiveness and therapeutic efficacy. This study aims to analyze the cost-effectiveness of using Lantus and Apidra insulin therapies.This research is an observational analytic study with a cross-sectional design, and data collection was conducted retrospectively at RSUD Dr. R. Soedjono Selong. The sample selection was based on predetermined inclusion and exclusion criteria. Observations were made on the Length of Stay (LOS) and Direct Medical Cost (DMC) for each sample. Based on LOS and DMC data, the Average Cost-Effectiveness Ratio (ACER) was calculated. The results showed that the average LOS for Lantus insulin use was 4 days, while for Apidra insulin use, it was 5 days. The average DMC for Lantus insulin was Rp.2,395,734, while for Apidra insulin, it reached Rp. 2,590,218. Based on LOS and DMC data, the ACER value for Lantus insulin was Rp 598,934/day, while for Apidra insulin, it was Rp 518,043/day. The use of Apidra insulin is more cost-effective because it has a lower ACER value.
Co-Authors Al-Adawiyah , Rosita Anjani, Rizky Puji Arief Rafsanjani Atiaturrahmaniah Atiaturrahmaniah Baiq Aryani Novianti Baiq Maylinda Gemantari Erma Ewisa Oktresia Ersi Arviana Ihsan Ewisa Oktresia Hardiyanti, Novi Hartini Haritani Hartono, M. Herry Hikmah, Rani Anggraini Leny Ramadhan Muhammad Zainul Majdi Novi Hardiyanti Puspawan Hariadi Ramadani, Lalu Khilal Sulistia Ardyati Sulistia Ardyati Tri Puspita Yuliana Yuliana , Tri Puspita