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All Journal Mutiara Medika: Jurnal Kedokteran dan Kesehatan Public Health of Indonesia Jurnal Penelitian Pendidikan IPA (JPPIPA) BERDIKARI : Jurnal Inovasi dan Penerapan Ipteks PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Akuntoteknologi : Jurnal Ilmiah Akuntansi dan Teknologi Pediomaternal Nursing Journal Empowerment : Jurnal Pengabdian Pada Masyarakat JARI Biosaintifika: Journal of Biology & Biology Education
Agus Suharto, Agus
Bagian Ilmu Patologi Anatomi, Fakultas Kedokteran dan Ilmu Kesehatan, Universitas Muhammadiyah Yogyakarta
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Environmental Science Health Professions Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Nursing Physics Public Health Social Sciences Other

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Study Guide Suharto, Agus
Mutiara Medika: Jurnal Kedokteran dan Kesehatan Vol 5, No 1 (2005)
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/mmjkk.v5i1.1868

Abstract

Tujuan Fakultas Kedokteran UMY adalah menghasilkan dokter yang profes¬sional, islami bervisi global dan mempunyai kemampuan manajerial. Untuk mencapai semua itu Fakultas Kedokteran berusaha dengan mengubah pendekatan pendidikan dari teacher centred approach ke student centred approach.Perubahan ini membawa dampak, salah satunya adalah dosen dituntut mampu membuat, mendesain, mengembangkan dan mengevaluasi media ajar yang dapat digunakan untuk mendukung proses belajar mahasiswanya.Fungsi tradisional media pembelajaran adalah untuk menyampaikan informasi sebanyak-banyaknya tentang isi materi pembelajaran kepada mahasiswa. Dalam inovasi mengembangkan media ajar, saat ini ada kecenderungan yang semakin popular dengan membuat study guides. Study guides selain berisi informasi inti juga menyatakan tujuan belajar, prasyarat suatu topic pembelajaran, learning opportunities yang tersedia, self assessment, dan lain-lain.
Hubungan Ekspresi p53 dengan Prognosis Hasil Terapi Radiasi pada Karsinoma Nasofaring Tejosukmono, Ario; Suharto, Agus
Mutiara Medika: Jurnal Kedokteran dan Kesehatan Vol 12, No 3 (2012)
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/mmjkk.v12i3.1029

Abstract

Pada karsinoma terjadi peningkatan proliferasi sel dibanding dengan apoptosis sel, sehingga sel akan tumbuh lebih banyak dari jumlah normalnya. Pada kondisi homeostasis, untuk dapat mengatur jumlah sel pada tubuh manusia, mekanisme utama tubuh adalah dengan menghasilkan p53. Protein p53 sebagai protein penghambat tumor mengaktifkan pembentukan p21 yang berperan untuk aktivasi beberapa komplek kinase tergantung siklin dan memutus siklus pembelahan sel. Tujuan penelitian ini untuk analisis hubungan ekspresi p53 terhadap prognosis radioterapi pada karsinoma nasofaring dengan metode retrospektif. Ekspresi p53 telah dicat imunohistokimia dan dianggap positif bila jumlah sel tumor positif lebih dari 10% dan dianalisis hubungan ekspresi p53 dengan prognosis pada pasien karsinoma nasofaring dengan radioterapi. Hasil penelitian menunjukkan dari 43 Pasien karsinoma nasofaring dengan terapi radiasi terdapat 8 orang (18,6%) meninggal selama perawatan. Berdasarkan jenis kelamin, 74,42% pasien adalah laki-laki dan 25,58% wanita. Kelompok usia 51 sd 60 tahun adalah yang terbanyak yaitu sebesar 14 kasus (32,56%). Terdapat hubungan yang bermakna antara ekspresi p53 dengan prognosis hasil terapi radiasi pada karsinoma nasofaring p = 0,000 (p 0,05). Disimpulkan bahwa ekspresi p53 yang positif akan memberikan prognosis yang lebih baik terhadap hasil terapi radiasi pada karsinoma nasofaring. In the cancer condition, there is increasing of cell proliferation than apoptosis, so cell will grow rapidly than normal. In normal homeostatic, to set the amount of the cells in human body, the primary body mechanism is producing gene p53. The p53 as protein cancer suppressor activate p21 that role to activate some of complex kinase  based on cyclin and cut mitosis cycle. The aims of this research to analyze relation p53 expression with prognosis of radiotherapy in nasofaringeal carcinoma using retrospective method. P53 expression strained by imunohistochemistry and considered positive if we find greater than 10% positif cell tumor then analyzed relation p53 expression with prognosis of radiotherapy in nasofaringeal carcinoma. The result shows from 43 patient nasofaringeal carcinoma with radiotherapy there are 8 patient (18,6%) died. 74,42% patient are male and 25,58% are female. 51-60 years old group is 14 cases (32,56%). There was significant correlation between prognosis and p53 expression p= 0,000 (p 0,05). The conclusion is that positive p53 expression will give a better prognostic for nasofaringeal carcinoma with radiotherapy.
Layanan Kesehatan Swadaya Masyarakat untuk Lansia Suharto, Agus; Bahiroh, Siti; Ramadhan, Cahyo Setiadi
Berdikari: Jurnal Inovasi dan Penerapan Ipteks Vol 7, No 2 (2019): August
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/bdr.7268

Abstract

The high number of elderly people in Dagen Hamlets, Pendowoharjo, Bantul requires special highlight, especially regarding the health care. This urgency is due to the fact that elderly people generally have accessibility limitations in addition to the remote location of health facilities. Therefore, health service which is practical and easy-to-reach/access by the elderly people needs to be managed to take place. The society empowerment effort, especially towards elderly people, was conducted step-by-step, involving socializations, trainings, practices, and local health service facility establishment. The success indicator achieved in this empowerment activities is shown by the improvement of people’s awareness, especially the elderly ones, towards the significance of health, health service post visitation intensity, and the development of the non-governmental health service facility.
PEMANFAATAN MULTIMEDIA MENGGUNAKAN GOOGLE SITES BAGI GURU-GURU SMP SMK PUTRA SATRIA SEBAGAI MEDIA PEMBELAJARAN JARAK JAUH Suharto, Agus
Jurnal Empowerment: Jurnal Pengabdian pada Masyarakat Vol 1 No 2 (2021): Oktober 2021
Publisher : Pondok Jurnal-LP2M STAI Darul Kamal

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1971.13 KB) | DOI: 10.51700/empowerment.v1i2.239

Abstract

Teachers and staff in carrying out their duties cannot be separated from the use of information technology, in several schools including partner schools, namely SMP & SMK PUTRA SATRIA. there are still many teachers and TU staff who are not familiar with the use of information technology. For this reason, it is necessary to increase skills through training in the use of Google application information system software. This activity is carried out in 3 stages, namely the preparation stage, then the Distance Learning training stage with Google Sites, Google Classroom, then the effectiveness evaluation stage with questionnaires by participants, Based on the data obtained from the questionnaire via google form about the effectiveness of distance learning using the Google Sites platform, google classroom, as follows very ineffective 7%, ineffective 10%, quite effective 10%, effective 67%, very effective 7%
Pengaruh Pertumbuhan Ekonomi, Jumlah Uang Beredar Dan Tingkat Bunga Terhadap Ekonomik Eksposur Perusahaan Perbankan Yang Terdaftar Di Bursa Efek Indonesia Tahun 2005 - 2015 Dengan Inflasi Sebagai Variabel Intervening Yusman, Yusman; Silaban, Berlin; Suharto, Agus
AKUNTOTEKNOLOGI : JURNAL ILMIAH AKUNTANSI DAN TEKNOLOGI Vol. 13 No. 2 (2021): AKUNTOTEKNOLOGI : JURNAL ILMIAH AKUNTANSI DAN TEKNOLOGI
Publisher : Universitas Buddhi Dharma/Fakultas Bisnis/Program Studi Akuntansi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31253/aktek.v13i2.928

Abstract

Penelitian ini pada dasarnya ingin mencoba memperlihatkan pengaruh variabel indipenden (pertumbuhan ekonomi, jumlah uang beredar dan BI rate) secara keseluruhan terhadap ekonomik eksposue sebagai variabel dependen, yang dibuktikan dengan nilai signifikansi uji F sebesar 0,0000. Meskipun secara uji parsial, variabel pertumbuhan ekonomi tidak memberikan pengaruh yang signifikan, karena nilai probabilitas variabel ini 0,3522 yang lebih besar dar nilai α = 0,05. Namun dua variabel indipenden lainnya, yaitu jumlah uang beredar dan BI rate memberikan nilai probabilitas yang signifikan, bahkan untuk varibel jumlah uang beredar mempunyai signifikansi yang sangat sempurna, yaitu dengan nilai probabilitas 0,0000. Uji asumsi klassik terhadap data penelitian ini juga terpenuhi, kecuali untuk uji auto korelasi terdapat korelasi positif. Meskipun telah dilakukan berbagai perbaikan uji DW, namun tetap tidak bisa menghilangkan adanya auto korelasi. Hasil penghitungan regresi dengan menggunakan program eviews (karena penelitian ini menggunakan data panel, yaitu gabungan antara data time series dengan data cross section) memberikan persamaan regressi sebagai berikut : Y = - 3,99E+8 + 903.413,7 X1 + 41.528.923 X2 + 1.177.065 X3. Interpretasi dari hasil persamaan regressi tersebut dapat di jelaskan sebagai berikut : Nilai konstanta sebesar - 3,99E+8 mempunyai arti apabila variabel pertumbuhan ekonomi, jumlah uang beredar dan BI rate tidak menmgalami perubahan sama sekali atau X1 = X2 = X3 = 0, maka besarnya ekonomik eksposur minus 3,99E+8. Koefisien β1 = 903.413,7 mempunyai arti setiap perubahan varibel X1 sebesar satu unit, dengan asumsi variabel lainnya konstan, maka ekeonomik eksposur akan meningkat sebesar 903.413,7 satuan. Koefisien β2 = 41.528.923 mempunyai arti setiap perubahan varibel X2 sebesar satu unit, dengan asumsi variabel lainnya konstan, maka ekeonomik eksposur akan meningkat sebesar 41.528.923 satuan. Koefisien β3 = 1.177.065 mempunyai arti setiap perubahan varibel X3 sebesar satu unit, dengan asumsi variabel lainnya konstan, maka ekeonomik eksposur akan meningkat sebesar 1.177.065 satuan.
Survival analysis of diabetes mellitus and cardiovascular patients with COVID-19: a secondary data analysis Nugroho, Ariyanto; Fadlilah, Siti; Susanto, Herry; Damayanti, Santi; Suharto, Agus; Sugiyarto, Sugiyarto
Public Health of Indonesia Vol. 10 No. 2 (2024): April - June
Publisher : YCAB Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36685/phi.v10i2.788

Abstract

Background: Patients with diabetes mellitus (DM) and cardiovascular disorders who suffer from COVID-19 may have an increased risk of death.  Objective: This study aims to analyze the time of death and influencing factors in patients with DM and cardiovascular disorders with COVID-19. Methods: We used a retrospective observational cohort study using medical records of COVID-19 patients treated at Dr Soeradji and Penembahan Senopati hospitals from March 2020 to June 2022. There were 2,959 participants: patients without comorbidities, with DM, and with cardiovascular problems. We extracted sociodemographic and clinical data on patient characteristics using medical records. Data analysis used Kaplan-Meier and Cox regression analysis to estimate survival probability and investigate predictors of death with a 5% significance level. Results: The median survival time was highest in the group without comorbidities (70.00) and lowest in the DM+others group (21.75). Years of treatment, age, presence of comorbidities, and type of hospital were related to the survival rate of COVID-19 patients (p<0.05). Diabetes mellitus and cardiovascular system disorders are significantly associated with survival of COVID-19 patients (p<0.001). There were significant differences between patients without cardiovascular disorders and patients with cardiovascular disorders (Non-Hypertension, Hypertension, and Hypertension + Others) adjusted by year, gender, age, and hospital type (p<0.001). There were significant differences between patients without DM and patients with DM (DM only, DM+Hypertension, and DM+Others) adjusted by year, gender, age, and hospital type(p<0.001). Conclusion: Years of treatment, age, gender, comorbid DM, and cardiovascular problems are associated with the survival rate of COVID-19 patients. Older age, DM patients who have comorbidities other than hypertension, and patients with cardiovascular issues other than hypertension show a greater risk of death than other groups. Key words: COVID-19, Diabetes Mellitus, Hypertension, Cardiovascular Diseases, Survival Rate.
The Alteration Level of VEGF of Colon Cancer Cell After Induction with Mandarin Orange (Citrus Reticulata) Peel Ethanol Extract Astuti, Yoni; Zuliana Utami, Anisa; Suharto, Agus; Yano, Yoshihiko; Aristyaning Putri, Wahyu
Biosaintifika: Journal of Biology & Biology Education Vol. 16 No. 2 (2024): August 2024
Publisher : Universitas Negeri Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15294/biosaintifika.v16i2.3401

Abstract

The natural ingredient-based therapy extracted from various plants is assumed more tolerable to cancer patients’ bodies than synthetic drugs. To tell successful novel cancer therapy, an indicator is needed to confirm the result. VEGF is a pro-angiogenic factor that leads the cancer cells’ invasion to another organ and is associated with high mortality in patients. Hence, the VEGF level is widely used as one of the successful cancer therapy indicators. Purposed of research elucidated the effect of Mandarin orange peel ethanol extract (EEKJM) to improve the reduction of VEGF levels in colon cancer in vitro. This study was an experimental posttest and control group design to analyze different level of VEGF on cancer cells at end of the study.  Research began with the preparation of EEKJM followed by a cytotoxic extract test using the MTT assay method. Furthermore, the measurement of VEGF levels by the VEGF ELISA kit protocol. One Way ANOVA was performed to analyze data.Results showed the cytotoxic test of the EEKJM and doxorubicin against WiDr cells was 240 g/ml and 1.59 µg/ml. VEGF levels showed decreasing after being induced with EEKJM and doxorubicin with doses ½ IC50 and ¼ IC50. Conclusion: EEKJM was able to reduce VEGF levels and viability of WiDr colon cancer cells. The advantages are as much as initial evidence of the ability of the orange to treat cancer even though further animal studies or evidence of a pathway of decrease of the VEGF or other signals are required.
PEMANFAATAN MULTIMEDIA MENGGUNAKAN GOOGLE SITES BAGI GURU-GURU SMP SMK PUTRA SATRIA SEBAGAI MEDIA PEMBELAJARAN JARAK JAUH Suharto, Agus
Empowerment: Jurnal Pengabdian pada Masyarakat Vol 1 No 2 (2021): Empowerment 2021
Publisher : LP2M STAI Darul Kamal NW Kembang Kerang-NTB

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51700/empowerment.v1i2.239

Abstract

Teachers and staff in carrying out their duties cannot be separated from the use of information technology, in several schools including partner schools, namely SMP & SMK PUTRA SATRIA. there are still many teachers and TU staff who are not familiar with the use of information technology. For this reason, it is necessary to increase skills through training in the use of Google application information system software. This activity is carried out in 3 stages, namely the preparation stage, then the Distance Learning training stage with Google Sites, Google Classroom, then the effectiveness evaluation stage with questionnaires by participants, Based on the data obtained from the questionnaire via google form about the effectiveness of distance learning using the Google Sites platform, google classroom, as follows very ineffective 7%, ineffective 10%, quite effective 10%, effective 67%, very effective 7%
Survival analysis of COVID-19 outcomes in pregnant and non-pregnant women: A secondary data study Retnaningsih, Listyana Natalia; Fadlilah, Siti; Suharto, Agus; Widaryanti, Rahayu; Sugimoto, Hiroshi; Arifin, Hidayat
Pediomaternal Nursing Journal Vol. 11 No. 1 (2025): VOLUME 11 NO 1 MARCH 2025
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/pmnj.v11i1.65421

Abstract

Introduction: Pregnant women are a population vulnerable to health problems. The morbidity and mortality of pregnant women with COVID-19 are higher compared with the rest of the population. This study aims to determine the survival rate of pregnant versus non-pregnant women with COVID-19. Methods: The study used a retrospective observational cohort design. Data were collected from Dr Soeradji Tirtonegoro and Penembahan Senopati hospitals on patients treated between March 2020 and June 2022. A total of 923 women diagnosed with COVID-19 were included in the study. Sociodemographic and clinical data on patient characteristics were extracted from medical records. Data analysis was conducted using Kaplan-Meier and Cox regression analyses to estimate survival probability and investigate predictors of death, with a 5% significance level. Results: Among 932 women with COVID-19, 231 deaths occurred. The median survival time for all participants was 30.56 days, while for pregnant women, it was 11.21 days, and for pregnant women with comorbidities, it was 9.68 days. Years of treatment, age, comorbidities, number of comorbidities and pregnancy were associated with survival rate (P-value < 0.001). Consistent results were also obtained for pregnant women’s age and number of comorbidities (P-value < 0.05). Significant differences between pregnant and non-pregnant patients remained after adjustment for year, sex, age and hospital type (P-value < 0.001). Conclusion: Pregnant women with COVID-19 have a higher risk of death compared with non-pregnant women. Keywords: comorbidity; COVID-19, female; pregnant women; survival analysis
PELATIHAN MEMBUAT WEBSITE CATALOG KARANG TARUNA PADA ANGGOTA TAMAN BACAAN PERIGI SAWANGAN KOTA DEPOK suharto, agus
JARI : Jurnal Pengabdian Kepada Masyarakat Republik Indonesia Vol. 3 No. 1 (2025): Maret
Publisher : PT Triputra Sejahtera Prima

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Abstract Community Service is part of the Tri Dharma of Higher Education which must be carried out every semester. The theme of this PKM activity is Web Catalog Creation Training for Karang Taruna and the facilities in it, namely the reading park. This theme was chosen to increase students' knowledge about how to create a web catalog, design, and program using relevant web technology. The socialization that will be carried out includes an introduction to the basics of creating a web catalog, providing an explanation of the functions and features that can be used in web development, and practicing its application to create a web catalog that can be used by Karang Taruna as a means of promotion and effective communication. With this training, it is hoped that members of the Karang Taruna can improve their competence in web development, which in the end can help them compete in the world of work and increase knowledge in the field of information technology. The output targets of the community service program implemented at the Perigi Reading Park are increasing the knowledge and skills of Karang Taruna members, activity videos, articles in print or online media, and journal articles. Keywords: Training; Web Catalog; Socialization Abstrak Pengabdian Kepada Masyarakat merupakan bagian dari Tri Dharma Perguruan Tinggi yang wajib dilakukan setiap semester. Tema pada kegiatan PKM kali ini adalah Pelatihan Pembuatan Web Catalog untuk Karang Taruna serta sarana yang ada di dalamnya, yaitu taman baca. Tema ini dipilih untuk menambah pengetahuan siswa-siswi tentang cara membuat web catalog, mendesain, dan memprogram dengan menggunakan teknologi web yang relevan. Sosialisasi yang akan dilakukan meliputi pengenalan dasar pembuatan web catalog, memberikan penjelasan mengenai fungsi-fungsi dan fitur yang dapat digunakan dalam pengembangan web, serta mempraktikkan penerapannya untuk membuat sebuah katalog web yang dapat digunakan oleh Karang Taruna sebagai sarana promosi dan komunikasi yang efektif. Dengan pelatihan ini, diharapkan anggota karang taruna dapat meningkatkan kompetensi mereka dalam pengembangan web, yang pada akhirnya dapat membantu mereka bersaing di dunia kerja serta menambah pengetahuan di bidang teknologi informasi. Target luaran dari program pengabdian kepada masyarakat yang dilaksanakan di Taman Baca Perigi adalah peningkatan pengetahuan dan skill anggota karang taruna, video kegiatan, artikel pada media cetak atau online, dan artikel jurnal. Kata Kunci: Pelatihan;Web Katalog; Sosialisasi
Co-Authors Andriansah, Zulfi Arifin, Hidayat Arip Kristiyanto Aristyaning Putri, Wahyu Ariyanto Nugroho Astuti, Yoni Fadilah, Muhamad Yudi Fahrudin , Endin Farizy , Salman Herry Susanto Hoga Saragih Jamhari Jamhari Luky Adrianto Rahayu Widaryanti Rahmawati, Iroh Ramadhan, Cahyo Setiadi Retnaningsih, Listyana Natalia Safitri, Helen Santi Damayanti Silaban, Berlin Siti Bahiroh Siti Fadlilah Sugimoto, Hiroshi Sugiyarto Sugiyarto YOSHIHIKO YANO Yusman, Yusman Zuliana Utami, Anisa