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Journal : Berkala Ilmu Kesehatan Kulit dan Kelamin

Non Bullous Congenital Ichthyosiform Erythroderma Setyowatie, Lita; Zulkarnain, Iskandar
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol 26, No 2 (2014): BIKKK AGUSTUS 2014
Publisher : Faculty Of Medicine Airlangga University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (901.839 KB) | DOI: 10.20473/bikkk.V26.2.2014.1-8

Abstract

Background: Non bullous congenital ichthyosiform erythroderma (NBCIE) is an inherited genodermatosis, very rare autosomal recessive inflammatory ichthyosis, chronic, characterized by dryness and scaling. Purpose: To describe the clinical manifestations of NBCIE since it is a rare case, occurs in 1 in 300.000 people. Case: Baby MR 5 month old, Javanese boy, with main complaint white scale and redness patches on almost all of his body since 1.5 month old. Born as collodion baby, then the membrane was slowly thinning and became generalized erythroderma on almost all of his body accompanied with fine white scale, large, thick, plate-like scale only on lower leg. No ectropion and eclabium. No relatives in the pedigree suffer from the same disease. Histopathology examination showed non-bullous congenital ichthyosiform erythroderma. Case management: Emollient after bath and pH balance soap. Conclusions: Diagnosis of NBCIE is established from history taking, clinical features, and histopathology examination. Emollient therapy and pH balance soap will eventually lead to improvement.Key words: non bullous congenital ichthyosiform erythroderma, genodermatosis, collodion baby.
Electrosurgery and 5% Imiquimod Cream as a Combination Therapy for Perianal Condyloma Acuminata in a HIV Patient Setyowatie, Lita; Faradila, Anandita
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 37 No. 2 (2025): AUGUST
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikkk.V37.2.2025.142-146

Abstract

Background: Condyloma acuminata (CA) is a common sexually transmitted infection caused by the human Papillomavirus (HPV) infection. It is characterized by single or multiple lesions in the anogenital area accompanied by itching, discharge, or bleeding. CA in HIV (human immunodeficiency virus) - positive patients can experience a low response to various therapeutic modalities, which may lead to consideration of choosing combination therapy to increase the effectiveness of therapy. Case: We report a case in a twenty-one-year old male with multiple warts on the perianal area. Within four months, the warts had covered the perianal area, with hemorrhoids emerging as complications. The patient had trichloroacetic acid treatment three times but did not respond. The patient is male who have sex with male, and there has been a history of multisexual partners. The diagnosis was made by clinical and histopathological examinations. The patient is HIV-positive and has been receiving antiretrovirals regularly. He got a combination therapy of electrosurgery and 5% imiquimod cream for 9 weeks and showed excellent results. Discussion: Standard topical medication is an effective treatment for condyloma acuminata, but infiltrative and recurrent lesions often require ablative and surgical treatment. Conclusion: Electrosurgery in combination with imiquimod proved to be effective and shortening the treatment regimen in the treatment of perianal CA.