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ATTENTION AND INTERNATIONAL HIV DEMENTIA SCALE (IHDS) DO NOT CORRELATE WITH CD4 COUNT IN HIV PATIENTS Arofah, Annisa Nurul; Rianawati, Sri Budhi; Rasyid, Harun Al; Rahayu, Masruroh
Malang Neurology Journal Vol 4, No 2 (2018): July
Publisher : Malang Neurology Journal

Background. Despite it is common neurocognitive domain that affected in patient with Human Immunodeficiency Virus (HIV) infection, attention domain is not assessed using International HIV Dementia Scale (IHDS), a common screening test to diagnose HIV-associated cognitive disorder. Detection of attention deficit in HIV patient is important as it can maintain the capacity to adherence to antiretroviral therapy and essential to activity daily living. CD4 is one of the markers for severity of HIV infection. Objective. We aims to correlate between CD4 with IHDS and CD4 with attention performance test, such as forward digit span test (FWD), backward digit span test (BWD), and trail making test A test (TMA).Methods. This is an analytic study using cross sectional design. 20 respondents are collected for the study using purposive sampling. Data is collected using instrument IHDS, FWD, BWD, and TMA.Results. Using the correlation of Eta, Eta 2 of CD4 and IHDS, CD4 and FWD, CD4 and BWD, also CD4 and TMA are 0.025, 0.022, 0.022 and 0.011.Conclusion. We concluded that CD4 have no correlation with test for attention domain and IHDS.

Catechins decrease neurological severity score through apoptosis and neurotropic factor pathway in rat traumatic brain injury Ratnawati, Retty; Arofah, Annisa Nurul; Novitasari, Anastasia; Utami, Sartika Dewi; Hariningsih, Made Ayu; Rahayu, Masruroh; Rianawati, Sri Budhi; Purnomo, Hari; Dalhar, Mochammad
Universa Medicina Vol 36, No 2 (2017)
Publisher : Faculty of Medicine, Trisakti University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/UnivMed.2017.v36.110-122

BACKGROUNDCatechins inhibits apoptosis through anti oxidant and anti inflamation pathway. Catechins also increases brain-derived neurotrophic factor (BDNF). There was a few research that explained the role of catechins in traumatic brain injury (TBI). The objective of the study was to evaluate the effect of catechins administration on neurologic severity score (NSS) through apoptosis and neurotropic pathway in traumatic brain injury rat model.METHODSA post test only controlled group design was performed using traumatic brain injury rat (Rattus novergicus) model through weight drop models. It was devided into negative control group, positive control group, TBI+catechins 513 mg/kgBW, TBI+catechins 926 mg/kgBW, TBI+catechins 1113 mg/kgBW. NSS was measured in the first hours, day three, and day seven. The expressions of NFkB, TNFa, Bcl-2, Bax, caspase 3, caspase 8, BDNF, and the numbers of apoptosis cells were evaluated by imunohistochemystry method. One way Anova and Kruskal Wwallis were used to analyse the data.Results TNFa, caspase 8, number of apoptosis cells were significantly decreased on the seventh day administration compared to the third day administration (p<0.05). Catechins increased the expression of Bcl-2/Bax and BDNF significantly (p<0.05). Yet, there were no significant differences between expression of caspase 3, NSS, Bcl-2/Bax ratio, and BDNF toward third days administration of catechins compared with seven days administration (p>0.050).ConclusionsAdministration of catechins decreased NSS through inhibiting inflammation and apoptosis, as well as induced the neurotrophic factors in rat brain injury. Catechins may serve as a potential intervention for TBI.

PENATALAKSANAAN STROKE TROMBOTIK: PELUANG PENINGKATAN PROGNOSIS PASIEN Nurul Arofah, Annisa
Saintika Medika: Jurnal Ilmu Kesehatan dan Kedokteran Keluarga Vol 7, No 1 (2011): Januari 2011
Publisher : Universitas Muhammadiyah Malang

Stroke is a disease that needs multidisciplinary approach and the incident is still increasing. Primary precaution, secondary precaution and tertiary precaution are needed to reduce the incident of stroke and number of impairment. Many progress of the studies about treatments for ischemic thrombotic stroke are hold great promise for the better outcome. Thrombolytic therapy is has a main role in the acute phase treatment for the vascular target but the window therapy is narrow. There is important to overcome strategies to enhance the efficacy of thrombolytic therapy. Besides, neuroprotective agents are also important to decrease the number of disability because they are used to protect the ischemic neuron from the irreversible injury. In animal models of stroke neuroprotective agents are also hold great promise but investigators are still searching for a safe and effective agent that can limit ischemic damage in human stroke. Clinical trials are still needed to improve a better guideline of ischemic thrombotic stroke. Keyword: stroke, thrombotic, guideline.

PENATALAKSANAAN STROKE TROMBOTIK: PELUANG PENINGKATAN PROGNOSIS PASIEN Annisa Nurul Arofah
Saintika Medika Vol. 7 No. 1 (2011): Januari 2011
Publisher : Universitas Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22219/sm.v7i1.1088

Stroke is a disease that needs multidisciplinary approach and the incident is still increasing. Primary precaution, secondary precaution and tertiary precaution are needed to reduce the incident of stroke and number of impairment. Many progress of the studies about treatments for ischemic thrombotic stroke are hold great promise for the better outcome. Thrombolytic therapy is has a main role in the acute phase treatment for the vascular target but the window therapy is narrow. There is important to overcome strategies to enhance the efficacy of thrombolytic therapy. Besides, neuroprotective agents are also important to decrease the number of disability because they are used to protect the ischemic neuron from the irreversible injury. In animal models of stroke neuroprotective agents are also hold great promise but investigators are still searching for a safe and effective agent that can limit ischemic damage in human stroke. Clinical trials are still needed to improve a better guideline of ischemic thrombotic stroke. Keyword: stroke, thrombotic, guideline.

The Influence Of Sleep Patterns Based On The Sleep Disturbance Scale For Children (Sdsc) On The Height Of Children Aged 8-11 Years Rosari Listiana; Annisa Nurul Arofah; Laksmitha Saktiono Safiitri; Hawin Nurdiana
Saintika Medika Vol. 18 No. 1 (2022): June 2022
Publisher : Universitas Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22219/sm.Vol18.SMUMM1.22153

Sleep main an essential role in human development because growth hormone works best during the slow wave phase. About 20-30% of children have sleep problems. Children's bedtime has fallen more than usual over the last century, with school-age children having the most significant rate of change. This study aims to determine the effect of sleep patterns on height in children of SD Muhammadiyah 4 Malang aged 8-11 years. The cross-section method was used in this study. The sample in this study were all boys aged 8-11 years up to 98 children who met the inclusion criteria in SD Muhammadiyah 4 Malang. Data on height and weight were obtained from schools, and sleep patterns were obtained from questionnaires filled out by parents. Statistical analysis used Fisher's exact test with significance at p = 0.5. The results of this study did not show a significant effect between the child is sleeping position and height (p = 0.649). Most 8-year-old participants had poorer sleep patterns than their parents' height in the relevant categories. SD Muhammadiyah 4 Malang There is no significant effect between sleep patterns and height in children aged 8-11.

Analisis Faktor Stress, Keteraturan Pola Makan dan Konsumsi Bahan Pangan Iritatif Terhadap Kejadian Dyspepsia A. Dedi Rusmanto; Fara Nindya Maharani; Meddy Setiawan; Annisa Nurul Arofah
CoMPHI Journal: Community Medicine and Public Health of Indonesia Journal Vol. 3 No. 2 (2022): Oktober
Publisher : Perhimpunan Dokter Kedokteran Komunitas dan Kesehatan Masyarakat Indonesia (PDK3MI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37148/comphijournal.v3i2.99

Stress, regular diet, and consumption of irritating food are some of the risk factors for dyspepsia. Medical students at the first level undergo a fairly high density of activities, where this requires an adaptation process that can cause stress. In stressful conditions, the regularity of eating patterns is disrupted. There are also many incidents of students consuming irritating foodstuffs.Aims of researchto analyze stress factors, regularity of eating patterns and consumption of irritating foodstuffs onthe incidence of dyspepsia in first-year medical faculty students.This research is an analytic observational study with a cross sectional study approach. The research activity was carried out at UMM Medical Faculty in November 2019 involving 60 students of the 2019 class. The sampling technique used was simple random sampling. The data analysis was carried out by the ichi-square test which was then carried out by the logistic regression test.This research shown76.7% of students suffer from dyspepsia, 65%experience stress, 61.7% have irregular eating patterns and 40% of students consume irritating foodstuffs. Stress and regularity in eating patterns affected the incidence of dyspepsia (p=0.022 and p=0.006), while irritative foods had no effect on dyspepsia (p=0.998).Stress and regularity of eating patterns affect the incidence of dyspepsia.

Dampak Akibat Implementasi Program JKN Terhadap Biaya Kesehatan di Fasilitas Kesehatan Tingkat Lanjutan Annisa Nurul Arofah; Viva Maiga Mahliafa Noor; Febri Endra Budi Setyawan; Dafa Azmi Syauqi Shihab
CoMPHI Journal: Community Medicine and Public Health of Indonesia Journal Vol. 3 No. 2 (2022): Oktober
Publisher : Perhimpunan Dokter Kedokteran Komunitas dan Kesehatan Masyarakat Indonesia (PDK3MI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37148/comphijournal.v3i2.104

The current implementation of JKN brings major changes in the health care and financing system, especially in hospitals. The payment system in hospitals has changed, which previously used a fee-for-service system, was changed to a prospective payment system using the INA-CBGs rate and BPJS Kesehatan was appointed as the implementing institution for the program. The INA-CBG's payment system was chosen because it is possible to control health costs, encourage quality services according to standards, limit unnecessary or excessive health services and encourage providers to carry out cost containment. This study aims to determine the impact of the implementation of the JKN program on health costs in FKTL. This research is a literature review (narrative review) by conductinga literature review of 12 journals. Journals were obtained from Google Scholar and PubMed searches with the keywords Impact of JKN on Healthcare Costs in FKTL OR Hospitals which were selected with the criteria of national and international journals with good reputation and indexed by SINTA and SCOPUS which were published no later than 2016. the purpose of this study and passed the selection. The results of the analysis show that the impact of JKN, especially on health costs, has an effect on the pattern ofJKN utilization by the community, patient satisfaction, hospital efficiency, Gross Profit Margin and Net Profit Margin of hospitals, and has an effect on hospital income. It can be concluded that there has been an influence on FKTL since the JKN era entered Indonesia.

Assessment of Sleep Patterns and Their Correlation with Height in Children Aged 8–11 Years: Insights from the Sleep Disturbance Scale for Children (SDSC) Ahmad mahfur; Safitri, Laksmitha Saktiono; Nurdiana, Hawin; Arofah, Annisa Nurul
Saintika Medika Vol. 20 No. 1 (2024): June 2024
Publisher : Universitas Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22219/sm.Vol20.SMUMM1.38539

Sleep plays a crucial role in human growth, particularly during slow-wave sleep when the growth hormone functions optimally. Sleep disturbances are prevalent in 20–30% of children. Over the past century, there has been a notable decline in children’s sleep duration, with the most significant reductions observed in school-aged children. This study investigates the relationship between sleep patterns and the height of boys aged 8–11 years at Muhammadiyah 4 Elementary School in Malang. A cross-sectional design was employed, involving 98 boys who met the inclusion criteria. Data on height and weight were collected from school records, while sleep pattern information was obtained through parent-completed questionnaires. Statistical analysis was conducted using Fisher's exact test with a significance level of p ≤ 0.05. The results revealed no significant association between sleep patterns and children's height (p = 0.649). Most participants were 8 years old, with poor sleep patterns observed. However, based on maternal and paternal height, the majority were categorized as having an appropriate height. This study concludes that there is no significant relationship between sleep patterns and the height of boys aged 8–11 years at Muhammadiyah 4 Elementary School in Malang

Hubungan Skor Paparan Faktor Risiko dengan Metode Quick Exposure Terhadap Keluhan LBP Pada PengrajinKeramik Rizqullah, Muhammad Daffa Ramadhani; Binarsa, Deka Bagus; Arofah, Annisa Nurul
World Health Digital Journal Vol. 1 No. 2 (2025)
Publisher : Institute of Advanced Knowledge and Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/wolgitj.v1i2.12

Sektor manufaktur ialah bagian penting dari perekonomian Indonesia. Sektor industri di Indonesia masih cenderung terfokus pada industri pengolahan. Industri pengolahan tetap menjadi fokus utama sektor industri Indonesia. Tujuan penelitian ini adalah untuk mengetahui hubungan hasil skor paparan faktor risiko dengan metode Quick Exposure Checklist (QEC) terhadap keluhan low back pain pada pengrajin keramik di sektor industri Kampung Keramik Dinoyo Malang. Metode penelitian studi cross sectional, dengan teknik statistik univariat dan bivariat. Hasil penelitian menunjukkan bahwa dari total responden, 10 orang (58,8%) mengalami keluhan LBP, sementara 7 orang (41,2%) tidak mengalami keluhan LBP. Berdasarkan hasil paparan risiko dengan metode QEC, tidak ada responden yang berada dalam kategori "acceptable" (dapat diterima). Analisis bivariat menunjukkan adanya hubungan yang signifikan antara paparan faktor risiko (berdasarkan QEC) dan keluhan LBP. Nilai koefisien korelasi (r) sebesar 0,493 dengan p-value 0,044 menunjukkan bahwa hubungan ini signifikan secara statistik pada tingkat kepercayaan 95% (p < 0,05). Temuan ini menunjukkan bahwa ada hubungan yang signifikan antara paparan faktor risiko dan keluhan LBP, yaitu semakin besar paparan terhadap risiko ergonomis, semakin tinggi kemungkinan seseorang mengalami keluhan LBP. Penelitian ini menegaskan pentingnya penerapan prinsip ergonomis dalam lingkungan kerja untuk mengurangi risiko LBP.

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