Article Per Year (5 Year)
p-Index From 2021 - 2026
1.084
P-Index
This Author published in this journals
All Journal Sains Natural: Journal of Biology and Chemistry JURNAL FARMASIMED (JFM) COMMUNITY : Jurnal Pengabdian Kepada Masyarakat Journal of Pharmaceutical and Sciences. Science and Education Journal
Putri Amalia
Universitas Malahayati
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Education Environmental Science Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Social Sciences Other

Published : 7 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 7 Documents
Search

 1 
Functional Group Profiling of Gelatin-Based Transparent Capsule Shells Using FTIR-ATR Spectroscopy Saddam Husein; Rafi Andrean Permana; Putri Amalia; Candra Saka Nusantari
Sains Natural: Journal of Biology and Chemistry Vol. 16 No. 2 (2026): Sains Natural
Publisher : Universitas Nusa Bangsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31938/jsn.v16i2.976

Abstract

Transparent capsule shells are widely used as oral dosage forms; however, information regarding the source of gelatin is often unclear, potentially affecting product quality, safety, and halal status. This study aimed to profile ten samples of transparent capsule shells obtained from online stores using Fourier Transform Infrared Spectroscopy-Attenuated Total Reflectance (FTIR-ATR) and to compare their spectral characteristics with bovine, porcine, and fish gelatin standards. This laboratory experimental study employed FTIR-ATR analysis within the wavelength range of 4500-650 cm⁻¹. The results demonstrated that all capsule samples exhibited characteristic gelatin absorption bands in the Amide A, Amide I, Amide II, and Amide III regions. Based on Principal Component Analysis (PCA) and comparison with gelatin standards, 9 out of 10 samples (90%) showed spectral similarity to porcine gelatin, while 1 sample (10%) showed similarity to fish gelatin. No samples demonstrated dominant similarity to bovine gelatin. Sample K2 was classified as being closer to fish gelatin, whereas samples K1, K3, K4, K5, K6, K7, K8, K9, and K10 were classified as being closer to porcine gelatin. These findings indicate that FTIR-ATR is effective for profiling the chemical characteristics of transparent capsule shells and can be utilized as an analytical tool for identifying gelatin sources, thereby supporting quality control and consumer safety
Sitotoksisitas Ekstrak Daun Kopi Robusta (Coffea canephora) terhadap Sel Vero Mastuti Widianingsih; M. Rofi Putra Bani; Putri Amalia
Journal of Pharmaceutical and Sciences JPS Volume 9 Nomor 3 (2026)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v9i3.1624

Abstract

Robusta coffee leaves (Coffea canephora) contain various bioactive compounds that may serve as natural antioxidants and potential phytopharmaceutical agents. The objective of this research to evaluate the antioxidant activity and cytotoxicity of the ethanol extract of robusta coffee leaves and to determine the relationship between antioxidant activity and cell viability. Antioxidant activity was assessed using the 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay, while cytotoxicity was evaluated on Vero cells using the MTT assay over a concentration range of 31.25-500 µg/mL. Vitamin C and doxorubicin were used as positive controls. The ethanol extract exhibited very strong antioxidant activity with an IC50 value of 22.456 µg/mL, while vitamin C showed an IC50 value of 4.217 µg/mL. Cytotoxicity testing demonstrated low toxicity toward Vero cells, with an IC50 value of 1512.857 µg/mL, whereas doxorubicin exhibited an IC50 value of 60.052 µg/mL. Pearson correlation analysis revealed a strong negative correlation between antioxidant activity and Vero cell viability (r = −0.93, p = 0.024). Despite this correlation, cell viability remained above 100% at all tested concentrations, indicating the absence of cytotoxic effects on normal mammalian cells. These findings suggest that the ethanol extract of robusta coffee leaves possesses potent antioxidant activity while maintaining a favorable safety profile, supporting its potential to be futher development as a source of  natural antioxidants and phytopharmaceutical candidate.
Comparison Of The Antifungal Activity Of Ethanolic Extracts From Leaves, Peel, And Seeds Of Gnetum Gnemon L. Against Candida albicans Tarisa Saputri; Putri Amalia; Dwi Susanti
Jurnal FARMASIMED (JFM) Vol 9 No 1 (2026): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v9i1.3991

Abstract

Background: Infections caused by Candida albicans remain a health concern, creating a need for natural antifungal alternatives. Melinjo (Gnetum gnemon L.) is known to contain secondary metabolites with potential antifungal activity Aim:  This study aimed to compare the antifungal activity of ethanol extracts of melinjo leaves, skin, and seeds against Candida albicans and to determine the plant part with the most effective antifungal activity based on the inhibition zone diameter. Methode: This laboratory experimental study employed the disk diffusion method. Extraction was performed using maceration with 96% ethanol, followed by phytochemical screening and antifungal activity testing against Candida albicans. Result: Data were analyzed using the Shapiro–Wilk test, Levene’s test, and Kruskal–Wallis test. Phytochemical screening showed that all three extracts contained alkaloids, flavonoids, tannins, saponins, terpenoids, and phenolic compounds, but were negative for steroids. The Kruskal Wallis test showed a significance value of 0.908 (p>0.05), indicating no significant difference in antifungal activity among the three extracts. The highest mean rank was observed for the seed extract (24.17), followed by the skin extract (22.70) and leaf extract (22.13). Conclusion: Melinjo seed extract exhibited the highest antifungal activity compared to leaf and skin extracts. However, all three extracts were still classified as resistant to Candida albicans based on standards established by the CLSI.
PEMBERDAYAAN MASYARAKAT MELALUI PEMANFAATAN LIMBAH PLASTIK MENJADI ECO-BRICK SEBAGAI BAHAN PEMBUATAN KURSI RAMAH LINGKUNGAN Putri Amalia; Habzsha Ribi; Nurbaidah Nurbaidah; Fajar Satryo; Frency Caka
COMMUNITY : Jurnal Pengabdian Kepada Masyarakat Vol. 6 No. 2 (2026)
Publisher : Pusat Pengembangan Pendidikan dan Penelitian Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51878/community.v6i2.15537

Abstract

ABSTRACT Domestic waste management in Tejosari Village remains constrained by the lack of initial sorting, allowing inorganic materials to potentially pollute the local environment in a sustained manner. This KKL-PPM program of Universitas Malahayati aimed to improve community knowledge and mentor Karang Taruna youth in practicing the workflow of sorting, cleaning, compacting, and assembling 24 plastic bottles into an eco-friendly chair. Field assistance was executed participatorily through waste management socialization, sorting demonstrations, and direct material compaction simulations alongside local residents. Evaluation results recorded an accumulation of 10 kg of household plastic waste alongside a significant increase in residents' cognitive understanding from an initial 15.4%–46.2% to 92.3%–100% post-training. Direct participant involvement successfully produced a functional seating unit for the community interaction space, although 23.1% of participants still required further guidance. The final reflection indicates that integrating education with ecobrick practice effectively builds initial ecological literacy at the site level, yet local institutional schemes and periodic mentoring remain necessary to ensure the sustainability of independent waste sorting habits. ABSTRAK Pengelolaan limbah domestik di Desa Tejosari masih terkendala oleh minimnya pemilahan awal, sehingga material anorganik berpotensi mencemari lingkungan lokal secara berkelanjutan. Kegiatan KKL-PPM Universitas Malahayati ini bertujuan meningkatkan pengetahuan masyarakat serta mendampingi pemuda Karang Taruna dalam mempraktikkan alur pemilahan, pembersihan, pemadatan, hingga perangkaian 24 botol plastik menjadi satu unit kursi ramah lingkungan. Pendampingan lapangan dieksekusi secara partisipatif melalui sosialisasi tata kelola sampah, demonstrasi pemilahan, hingga simulasi pemadatan material anorganik secara langsung bersama warga. Hasil evaluasi mencatat akumulasi 10 kg sampah plastik rumah tangga serta peningkatan signifikan pada pemahaman kognitif warga dari kondisi awal 15,4%–46,2% menjadi 92,3%–100% pascapelatihan. Keterlibatan langsung peserta berhasil mewujudkan satu unit perabot duduk fungsional bagi ruang interaksi warga, meskipun 23,1% peserta masih memerlukan pengerjaan lanjutan. Pemaknaan akhir menunjukkan bahwa integrasi edukasi dan praktik ecobrick efektif membentuk pemahaman ekologis awal di tingkat tapak, namun skema kelembagaan lokal dan pendampingan berkala tetap diperlukan untuk menjamin keberlanjutan kebiasaan pemilahan sampah secara mandiri.
Dosage-Controlled Photocatalysis Of ZnO/TiO₂/Biochar For Efficient Removal Of Tartrazine Under UV–Visible Irradiation Sella Saputri; Putri Amalia; Saddam Husein
Science and Education Journal (SICEDU) Vol 5 No 3 (2026): Science and Education Journal 2026
Publisher : LPPM Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/sicedu.v5i3.1411

Abstract

Tartrazin merupakan zat warna sintetis yang banyak digunakan dalam industri pangan, farmasi, dan minuman serta memiliki struktur kimia yang relatif stabil sehingga sulit dihilangkan melalui proses pengolahan limbah konvensional. Fotokatalisis menggunakan material semikonduktor menjadi salah satu pendekatan yang potensial untuk menguraikan zat warna melalui pembentukan spesies oksidatif reaktif. Kombinasi TiO₂, ZnO, dan biochar dikembangkan untuk meningkatkan kinerja fotokatalitik melalui sinergi antara aktivitas semikonduktor dan kemampuan adsorpsi biochar. Proses fotodegradasi dilakukan menggunakan fotokatalis TiO₂/ZnO/Biochar dengan variasi dosis 0; 0,1; dan 0,5 g dalam 500 mL larutan model selama 120 menit menggunakan penyinaran UV-Vis. Konsentrasi tartrazin dianalisis menggunakan spektrofotometer UV-Vis berdasarkan perubahan absorbansi selama proses degradasi. Dosis 0,1 g memberikan kinerja fotokatalitik terbaik dengan efisiensi degradasi sebesar 74% lebih tinggi dibandingkan penyinaran UV A-B sebesar 48% dan adsorpsi dalam kondisi gelap sebesar 19%  setelah 120 menit. Peningkatan dosis katalis tidak meningkatkan efisiensi secara proporsional, yang diduga berkaitan dengan meningkatnya penghamburan cahaya dan aglomerasi partikel. Hasil ini menunjukkan bahwa TiO₂/ZnO/Biochar berpotensi digunakan sebagai fotokatalis untuk pengolahan limbah yang mengandung zat warna tartrazin.
Analisis Profil Metabolit Ekstrak Etanol Kulit Singkong (Manihot Esculenta Crantz) Dengan LC-HRMS Putu Happy Meldiana; Tutik Tutik; Putri Amalia
Science and Education Journal (SICEDU) Vol 5 No 3 (2026): Science and Education Journal 2026
Publisher : LPPM Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/sicedu.v5i3.1587

Abstract

Kulit singkong (Manihot esculenta Crantz.) merupakan salah satu limbah pertanian yang berpotensi untuk dimanfaatkan karena mengandung berbagai senyawa metabolit. Penelitian ini bertujuan untuk mengetahui profil metabolit pada ekstrak etanol kulit singkong menggunakan instrumen Liquid Chromatography–High Resolution Mass Spectrometry (LC-HRMS). Sampel diekstraksi menggunakan metode maserasi dengan pelarut etanol, kemudian dilakukan skrining fitokimia serta analisis profil metabolit menggunakan LC-HRMS dengan mode ionisasi positif (ESI+) dan negatif (ESI−). Identifikasi senyawa dilakukan berdasarkan nilai m/z, waktu retensi, serta karakteristik spektrum massa yang dibandingkan dengan basis data senyawa. Hasil analisis LC-HRMS menunjukkan bahwa terdapat 92 senyawa yang berhasil diidentifikasi, terdiri atas 62 metabolit primer (67,39%), 16 metabolit sekunder (17,39%), dan 15 senyawa lain (16,30%). Golongan senyawa yang teridentifikasi meliputi lipid sebesar 25,8%, karbohidrat 22,58%, protein 16,12%, fenolik 10,75%, alkaloid 5,32%, vitamin 2,1%, dan terpenoid 1,07%. Metabolit sekunder dengan kelimpahan relatif tertinggi adalah (2S)-2-Butanol O-[β-D-Apiofuranosyl-(1→6)-β-D-glucopyranoside] sebesar 0,41%.
Sitotoksisitas Ekstrak Daun Kopi Robusta (Coffea canephora) terhadap Sel Vero Mastuti Widianingsih; M. Rofi Putra Bani; Putri Amalia
Journal of Pharmaceutical and Sciences JPS Volume 9 Nomor 3 (2026)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v9i3.1624

Abstract

Robusta coffee leaves (Coffea canephora) contain various bioactive compounds that may serve as natural antioxidants and potential phytopharmaceutical agents. The objective of this research to evaluate the antioxidant activity and cytotoxicity of the ethanol extract of robusta coffee leaves and to determine the relationship between antioxidant activity and cell viability. Antioxidant activity was assessed using the 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay, while cytotoxicity was evaluated on Vero cells using the MTT assay over a concentration range of 31.25-500 µg/mL. Vitamin C and doxorubicin were used as positive controls. The ethanol extract exhibited very strong antioxidant activity with an IC50 value of 22.456 µg/mL, while vitamin C showed an IC50 value of 4.217 µg/mL. Cytotoxicity testing demonstrated low toxicity toward Vero cells, with an IC50 value of 1512.857 µg/mL, whereas doxorubicin exhibited an IC50 value of 60.052 µg/mL. Pearson correlation analysis revealed a strong negative correlation between antioxidant activity and Vero cell viability (r = −0.93, p = 0.024). Despite this correlation, cell viability remained above 100% at all tested concentrations, indicating the absence of cytotoxic effects on normal mammalian cells. These findings suggest that the ethanol extract of robusta coffee leaves possesses potent antioxidant activity while maintaining a favorable safety profile, supporting its potential to be futher development as a source of  natural antioxidants and phytopharmaceutical candidate.
Co-Authors Candra Saka Nusantari Dwi Susanti Fajar Satryo Frency Caka Habzsha Ribi M. Rofi Putra Bani Mastuti Widianingsih Nurbaidah Nurbaidah Putu Happy Meldiana Rafi Andrean Permana Saddam Husein Sella Saputri Tarisa Saputri Tutik Tutik