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All Journal JURNAL PENELITIAN PERAWAT PROFESIONAL Nusantara Hasana Journal Health Research Journal of Indonesia Obat: Jurnal Riset Ilmu Farmasi dan Kesehatan
Oktafany Oktafany
Universitas Lampung
Agriculture, Biological Sciences & Forestry Humanities Dentistry Economics, Econometrics & Finance Education Health Professions Medicine & Pharmacology Nursing Public Health Veterinary

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Efektifitas Pemberian Vitamin A pada Ibu Nifas dan Bayi Poppy Monika Sari; Suharmanto Suharmanto; Oktafany Oktafany
Jurnal Penelitian Perawat Profesional Vol 5 No 2 (2023): Mei 2023, Jurnal Penelitian Perawat Profesional
Publisher : Global Health Science Group

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/jppp.v5i2.1430

Abstract

Vitamin A memiliki segudang khasiat untuk mendefisiensikan angka kematian dan kesakitan, serta bermanfaat bagi pertumbuhan manusia, dan juga mengambil peran terhadap sistem imunitas tubuh, memproteksi tubuh dari terjangkitnya berbagai infeksi seperti campak, diare, dan ISPA. Kekurangan vitamin A dapat meningkatkan risiko berbagai macam penyakit seperti xerofthalmia, kerusakan mata yang berujung kebutaan, serta meningkatkan risiko kematian. Berdasarkan hasil riset yang diperoleh dari Profil kesehatan Indonesia tahun 2017, persentase dalam pemberian vitamin A pada ibu nifas telah mencapai angka 94,73%. Hal serupa juga terjadi di tahun sebelumnya, yang mana di tahun 2016 persentase dalam pemberian vitamin A pada ibu nifas memiliki persentase sebesar 90,1%, dan mengalami peningkatan di tahun berikutnya. Hal tersebut telah melewati standar nasional dalam pemberian persentase dalam pemberian vitamin A pada ibu nifas yakni sebesar 82%. Provinsi di Indonesia yang memiliki jangkauan tertinggi dalam pemberian vitamin A adalah Kalimantan Utara dengan persentase 98,49%, sedangkan provinsi dengan persentase terendah yakni Papua dengan total keseluruhan sebesar 76,61%. Pemberian vitamin A pada ibu nifas merupakan bentuk upaya pencegahan terjadinya kekurangan vitamin A yang bertujuan untuk menjaga kesehatan bayi dalam memproteksi diri terhadap penyakit xerophthalmia. Sumber utama vitamin A terbesar yang memungkinkan diterima oleh bayi yakni berasal dari ASI.
Hubungan Tingkat Stres dan Kualitas Tidur pada Mahasiswa Farmasi Febya Yuhendra Putri; Oktafany Oktafany; Nurmasuri Nurmasuri; Ihsanti Dwi Rahayu
Health Research Journal of Indonesia Vol 4 No 5 (2026): Health Research Journal of Indonesia
Publisher : CV. Wadah Publikasi Cendekia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63004/hrji.v4i5.1296

Abstract

Latar Belakang: Stres merupakan respons terhadap tuntutan yang melebihi kemampuan individu dan dapat berdampak pada kualitas tidur. Mahasiswa farmasi berisiko mengalami stres akibat beban akademik yang tinggi, sehingga berpotensi mengalami gangguan tidur. Penelitian ini bertujuan untuk mengetahui hubungan antara tingkat stres dengan kualitas tidur mahasiswa aktif Program Studi Farmasi. Metode: Penelitian ini merupakan studi kuantitatif analitik dengan pendekatan cross sectional. Subjek penelitian ini adalah mahasiswa aktif Program Studi Farmasi Universitas Lampung. Teknik pengambilan sampel dengan proportionate stratified random sampling dengan jumlah sampel 210 responden. Pengukuran tingkat stres menggunakan Perceived Stress Scale (PSS-10) dan kualitas tidur dengan Pittsburgh Sleep Quality Index (PSQI). Analisis data bivariat menggunakan uji Spearman rank correlation. Hasil: Mayoritas responden mengalami tingkat stres sedang (81%) dan kualitas tidur yang buruk (79%). Hasil uji bivariat menggunakan uji Spearman rank menunjukkan adanya hubungan yang signifikan antara tingkat stres dengan kualitas tidur (p< 0,001; r= 0,273) dengan kekuatan korelasi lemah dan arah hubungan positif. Simpulan: Terdapat hubungan yang signifikan antara tingkat stres dan kualitas tidur mahasiswa aktif Program Studi Farmasi Universitas Lampung.
Pengaruh Pemberian Pill Card terhadap Kepatuhan Minum Obat Antihipertensi pada Pasien Hipertensi Rawat Jalan Puskesmas Rawat Inap Satelit Bandar Lampung Audry Lintang Hasanuddin; Rasmi Zakiah Oktarlina; Dwi Aulia Ramdini; Oktafany Oktafany
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 4 No. 1 (2026): Januari: OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v4i1.2004

Abstract

Hypertension is one of the most common non-communicable diseases in Indonesia. Hypertensive patients must have high self-efficacy to comply with antihypertensive medication so that blood pressure can be controlled and complications prevented. Therefore, intervention is needed to improve therapy compliance. One intervention that can be given is the provision of pill cards. This study was a quasi-experimental design with a pre-intervention post-intervention control group design. Sampling was conducted using non-probability purposive sampling from July to September 2025. A total of 106 respondents were divided into two groups, with 53 respondents in the control group and 53 respondents in the intervention group. The control group was only given the MMAS-8 questionnaire, while the intervention group was given pill cards and the MMAS-8 questionnaire. In the intervention group, prior to intervention, 25 patients (47.2%) had low compliance, 21 patients (39.6%) had moderate compliance, and 7 patients (13.2%) had high compliance. After the intervention, there was a significant increase, with 21 patients (39.6%) showing high compliance, 26 patients (49.1%) showing moderate compliance, and 6 patients (11.3%) showing low compliance. Providing pill cards to outpatients with hypertension can improve patient medication adherence. Based on the results of the Wilcoxon Signed Ranks Test, a value of (p<0.001) was obtained, indicating that H0 was rejected and there was a significant effect.
Hubungan Kepatuhan Minum Obat dengan Tekanan Darah pada Pasien Hipertensi: Literatur Review Tasya Aprilia Pubioganda; Oktafany Oktafany; Citra Yuliyanda Pardilawati
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 4 No. 1 (2026): Januari: OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v4i1.2053

Abstract

Hypertension is a chronic condition that requires long-term management due to its strong association with an increased risk of serious complications when blood pressure is not adequately controlled. One of the key factors influencing the success of hypertension management is patient adherence to antihypertensive medication. However, suboptimal adherence remains a common problem and may lead to poor therapeutic outcomes. This literature review aimed to examine the relationship between adherence to antihypertensive medication and blood pressure control among patients with hypertension. A systematic search of the literature was conducted using the PubMed and Google Scholar databases with relevant keywords combined through Boolean operators. The selected articles were screened based on predefined inclusion and exclusion criteria, including original research articles published within the last ten years, accessible in full text, and addressing the association between medication adherence and blood pressure in hypertensive patients. The findings of the reviewed studies indicate that most articles reported a significant relationship between medication adherence and blood pressure levels. Patients with higher adherence to antihypertensive therapy tended to achieve better blood pressure control compared to those with lower adherence. Although variations in the strength of the reported associations were observed across studies, the overall direction of the relationship was consistent. These results suggest that adherence to antihypertensive medication plays an essential role in achieving optimal blood pressure control. Therefore, this review highlights the importance of continuous efforts to improve patient adherence as part of effective hypertension management strategies aimed at reducing the risk of long-term complications.
DUAL OREXIN RECEPTOR ANTAGONIST (DORA) SEBAGAI TERAPI INSOMNIA: SEBUAH TINJAUAN PUSTAKA Dianda Faradiba Wardani; Oktafany Oktafany; Anisa Nuraisa Jausal; Oktadoni Saputra
Nusantara Hasana Journal Vol. 5 No. 8 (2026): Nusantara Hasana Journal, January 2026
Publisher : Yayasan Nusantara Hasana Berdikari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59003/nhj.v5i8.1832

Abstract

Insomnia affects more than 852 million adults worldwide and 43.7% of individuals aged ≥19 years in Indonesia, highlighting the need for effective and safe therapy. Benzodiazepines and Z-drugs are commonly used but are associated with risks of tolerance and dependence. Dual orexin receptor antagonists (DORAs) have emerged as a more selective therapeutic alternative. A systematic literature review was conducted using PubMed and Google Scholar, focusing on meta-analyses of suvorexant, lemborexant, and daridorexant. Suvorexant improved subjective total sleep time (MD −19.10), subjective time to sleep onset (MD −8.23), and subjective wake after sleep onset (MD −6.45). Lemborexant at doses of 5–10 mg was effective in improving wake after sleep onset (MD −19.90; −22.24) and sleep onset latency (MD −9.23; −12.56). Daridorexant at doses of 25–50 mg reduced wake after sleep onset (MD −0.30; −0.53) and latent persistent sleep (MD −0.30; −0.53). Adverse effects of DORAs include somnolence, daytime sleepiness, fatigue, abnormal dreams, and nasopharyngitis. Overall, DORAs demonstrated significant effectiveness on subjective sleep parameters compared with control groups, with variations in effect size and safety profiles. DORAs may be considered effective and safe treatments for insomnia, with drug and dose selection tailored to clinical needs.
Co-Authors Anisa Nuraisa Jausal Audry Lintang Hasanuddin Citra Yuliyanda Pardilawati Dianda Faradiba Wardani Dwi Aulia Ramdini Febya Yuhendra Putri Ihsanti Dwi Rahayu Nurmasuri Nurmasuri Oktadoni Saputra Poppy Monika Sari Rasmi Zakiah Oktarlina Suharmanto Suharmanto Tasya Aprilia Pubioganda