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All Journal Dimas: Jurnal Pemikiran Agama untuk Pemberdayaan Proceeding International Conference on Global Resource Conservation Jurnal Pendidikan Biologi Indonesia Science Education and Application Journal Prosiding SNPBS (Seminar Nasional Pendidikan Biologi dan Saintek) Jurnal Pendidikan: Teori, Penelitian, dan Pengembangan
Arindra Trisna Widiansyah, Arindra Trisna
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Economics, Econometrics & Finance Education Energy Environmental Science Health Professions Social Sciences Other

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Virtual Screening of Natural Compounds for HIV 1 Reverse Transcriptase Inhibitor as Potential Drug’s Candidate Fadilah, Rizka Elan; Fauzi, Ahmad; Widiansyah, Arindra Trisna; Wijayanti, Erna
Proceeding International Conference on Global Resource Conservation Vol 6, No 1: Proceeding of 6th ICGRC 2015
Publisher : Proceeding International Conference on Global Resource Conservation

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (0.209 KB)

Abstract

AIDS is one of mayor health problem in the world, commonly caused by Human Immunodeficiancy virus 1 (HIV-1).  Reverse transcriptase is the target of the most widely used treatments for AIDS. One of the problem from treatments is drug resistant. This research aim to discover a new potential drug’s candidate from natural compound to inhibit activity of HIV 1 Reverse Transcriptase. Top ten compounds from Specs Natural Products database as the result of virtual screening by MTIOpenScreen are docked and analyzed using Pyrx 0.8 software. Based on analysis and visualization of 2D and 3D sructure using LigPlus and PyMol softwares, known that ZINC57657 (-8 Kcal/mol)and common drug against HIV 1 Reverse Transcriptase, Lamivudine (-5,6 Kcal/mol) equally capable to bind in several amino acids (Thr 131 and Gln 23) located in the active site of HIV 1 Reverse Transcriptase.Keywords: Drug’s candidate; HIV 1 reverse transcriptase; natural compounds; virtual screening
6-Gingerol from Zingiberaceae as a Result of Reverse Docking for Prostate’s Cancer Potential Drug Candidate Setyanto, Haqqi Anajili; Widiansyah, Arindra Trisna; Mustofa, Zainul
Proceeding International Conference on Global Resource Conservation Vol 6, No 1: Proceeding of 6th ICGRC 2015
Publisher : Proceeding International Conference on Global Resource Conservation

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (0.209 KB)

Abstract

Prostate cancer is a cancer that attacks the prostate gland causing the death rate which is high enough. One of the causes of prostate cancer is the androgen receptor (AR) in the gland cells that initiates the formation of excess cell proliferation, thus causing prostate cancer. AR inhibitor that is known is antiandrogen (biculatamide and enzalutamide). This study aimed to test the 6-gingerol compound of ginger as an AR inhibitor drug candidate for prostate cancer using silico methode. The 3D structure of the 6-gingerol compound was taken from PubChem, the prediction of targeted protein used SwissTargetPrediction and Pharmapper, analysis and docking 6-gingerol and antiandrogens with AR using Pyrx software, visualization compounds and protein interactions using PyMOLsoftware. Visualization results shows that the interaction of 6-gingerol, biculatamide, and enzalutamide with AR have the same site. This proves that the 6-gingerol is potential as anAR inhibitor candidate.Keywords: 6-gingerol; prostate’s cancer; reverse docking
The Inventory of Aquatic Macroinvertebrates in Various Waterfall in East Region of Malang, East Java Wijayanti, Erna; Fauzi, Ahmad; Widiansyah, Arindra Trisna; Mustofa, Zainul; Setyanto, Haqqi Anajili; Sukoco, Restu Megadiana; Nuha, Ulin; Fadilah, Rizka Elan
Proceeding International Conference on Global Resource Conservation Vol 6, No 1: Proceeding of 6th ICGRC 2015
Publisher : Proceeding International Conference on Global Resource Conservation

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (0.209 KB)

Abstract

Indonesia as Maritime Island has many water regions. Waterfall is one of the water region that has a large number of aquatic macroinvertebrates. The aim of this research is to collect and identify the various aquatic macroinvertebrates that can be found in several waterfalls in east Region of Malang, East Java. The research was carried out on September until November 2015 in six waterfalls: Coban Jahe, Coban Pelangi, Coban Trisula, Coban Kembar, Coban Ringin Gantung and Coban Pitu. Dragnet was used to collect the samplesof aquatic macroinvertebrates in some sampling point. The result of this research was found 38 families that belonged to 18 ordo in 6 different classes: Insecta, Oligochaeta, Gastropoda, Hirudinae, Turbellaria, and Crustacea. The information about the inventory of aquatic macroinvertebrates will give another suggestion for the local government to conserve this animals especially waterfall environment, not only as tourist area but also as a source of knowledge to do another research. Keywords: Aquatic macroinvertebrates; inventory; Malang; waterfalls
I-invertebrata as an android-based learning media for molluscs, arthropods, and echinoderms identification and its influence on students motivation Widiansyah, Arindra Trisna; Indriwati, Sri Endah; Munzil, Munzil; Fauzi, Ahmad
Jurnal Pendidikan Biologi Indonesia Vol 4, No 1 (2018): MARCH
Publisher : University of Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1022.976 KB) | DOI: 10.22219/jpbi.v4i1.5476

Abstract

In Zoology course, students often have difficulty to identify several invertebrates. Android-based learning media is currently an alternative way of solving some problems during the learning process. Therefore, android-based learning media that assist students to identify invertebrates was developed in this study. This research method used to research and development model (R&D) developed by Borg and Gall (1983) that consisting 10 steps, that are research and data collection; planning the educational product; developing the products preliminary form; initial field testing; the first revision of main product; main field testing; operational product revision; operational field testing; final product revision; and dissemination. The validation results from the material expert I, material expert II, and media experts were 96.6%; 94.3%; and 94.7%, respectively.  That results concluded I-Invertebrata was feasible for use in learning but requires minor revision. Furthermore, the results of quasi-experimental research that was analyzed by using analysis of covariance test showed the learning motivation of students who use I-Invertebrata is significantly higher than students who do not use I-Invertebrata.
Pemberdayaan Peternak melalui Pembuatan Biogas sebagai Solusi Limbah Kotoran Ayam Ras Petelur Widiansyah, Arindra Trisna; Rahayu, Anita Budi
Dimas: Jurnal Pemikiran Agama untuk Pemberdayaan Vol 19, No 2 (2019)
Publisher : LP2M of Institute for Research and Community Services - UIN Walisongo

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (570.782 KB) | DOI: 10.21580/dms.2019.192.5137

Abstract

The business of laying hens is a business sector that provides a very large role in meeting the needs of animal protein and various industrial needs. This role cannot be replaced by vegetable protein sources. According to partners besides having great opportunities and benefits, laying hens also have problems, one of which is chicken manure. Mr. Hakim has tried several ways to remove the odor, such as raising the foundation of the cage so that it is not submerged by rainwater, spreading lime powder, and spraying EM4 liquid directly into chicken manure. But apparently not effective at reducing odors. One of the technical recommendations is the making of Biogas as an alternative energy source producing fuel substitutes for LPG gas, firewood, lighting and organic fertilizer. The results of community service activities to date have been the availability of biogas as an alternative energy producer for the use of biogas stoves and petromax lamps, as well as increased partner knowledge about biogas.Usaha sektor peternakan ayam ras petelur merupakan bidang usaha yang memberikan peranan sangat besar dalam pemenuhan kebutuhan protein hewani dan berbagai keperluan industri. Peranan ini tidak dapat di gantikan oleh sumber protein nabati. Menurut mitra disamping memiliki peluang dan manfaat yang besar, peternakan ayam ras petelur juga memiliki permasalahan salah satunya yaitu kotoran ayam tersebut. Bapak Hakim sudah mencoba beberapa cara untuk menghilangkan bau tersebut seperti, meninggikan pondasi kandang agar tidak terendam air hujan, menebar serbuk kapur, serta menyemprot cairan EM4 langsung ke kotoran ayam. Namun ternyata belum efektif mengurangi bau. Salah satu rekomendasi teknis adalah pembuatan Biogas sebagai salah satu sumber energi alternatif penghasil bahan bakar pengganti gas LPG, kayu bakar, penerangan dan pupuk organik. Hasil kegiatan pengabdian sampai saat ini adalah tersedianya biogas sebagai penghasil energi alternatif untuk pemakaian kompor biogas dan lampu petromak, serta peningkatan pengetahuan mitra tentang biogas yang meningkat.
Implementation of Problem-Based Learning Model Using Youtube Media to Improve Numeracy Literacy of 8th Grade Students Lestari, Ririn Umi; Widiansyah, Arindra Trisna
Science Education and Application Journal Vol 7 No 1 (2025): Science Education and Application Journal
Publisher : Program Studi Pendidikan IPA, Universitas Islam Lamongan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30736/seaj.v7i1.1156

Abstract

Application of Problem-Based Learning Model Based on Youtube Media to Improve Students’ Numeracy Literacy. In eighth grade, kids' limited numeracy literacy abilities make it difficult for them to understand science. One innovative solution is the project-based learning (PBL) approach, incorporating YouTube material. Applying the Problem Based Learning (PBL) pedagogy with the digital media platform YouTube, this research seeks to enhance students' numeracy literacy abilities. The participants in this Classroom Action Research (PTK) study are thirty eighth graders from class 8A. There were two rounds to this study. This research measured students' numeracy literacy abilities using data collected via interviews, observations, and tests, which were analysed descriptively. The study found that although students' average exam scores climbed by 14.5 points to 78.2 in Cycle II, they were 63.7 in Cycle I. Results show that eighth graders at SMP Negeri 2 Berbek may benefit from the Problem Based Learning approach, especially in science, when they use YouTube as a learning tool. The researchers recommend doing future experiments over a longer period to examine the persistent influence of YouTube-based PBL on students' numeracy, since the time constraint led to less than optimum results.
Implementation of Animated Videos to Improve the Science Learning Outcomes of Junior High School Students Nabila, Athaya Safa; Widiansyah, Arindra Trisna
Science Education and Application Journal Vol 7 No 2 (2025): Science Education and Application Journal
Publisher : Program Studi Pendidikan IPA, Universitas Islam Lamongan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30736/seaj.v7i2.1157

Abstract

In the digital era, the use of animated videos is necessary as a learning medium because it presents visual and audio forms without the need for direct observation. This study specifically focuses on improving learning outcomes in science subjects. This classroom action research was conducted in two cycles following Kemmis and Taggart’s model (1988). The research subjects involved were 24 seventh-grade students from SMP NU Miftakhul Jannah because the learning resources available at the school are not yet varied. Data were collected through observation and tests. Quantitative data analysis shows an increase from cycle I to cycle II from 58.24% to 83.2 %. These findings suggest that animated videos can serve as an effective tool for improving student learning outcomes, particularly in technology-integrated education.
Inventarisasi Jenis dan Potensi Mollusca di Zona Pasang Surut Tipe Substrat Berbatu Pantai Gatra Kabupaten Malang Widiansyah, Arindra Trisna; Indriwati, Sri Endah; Arief, Munzil
Prosiding SNPBS (Seminar Nasional Pendidikan Biologi dan Saintek) 2016: Prosiding SNPBS (Seminar Nasional Pendidikan Biologi dan Saintek)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (764.349 KB)

Abstract

Mollusca memiliki rentangan habitat yang cukup luas, tidak terkecuali di zona intertidal (pasang surut). Berdasarkan kondisi lingkungan/substrat, zona pasang surut dibedakan menjadi substrat berbatu, berpasir, dan berlumpur. Dari semua jenis zona pasang surut, substrat berbatu yang tersusun dari bahan yang keras merupakan daerah yang paling padat makroorganismenya. Permukaan batuan yang keras berfungsi melindungi organisme dari panas dan predator serta sebagai substrat yang baik untuk tumbuh dan berkembang berbagai jenis tumbuhan dan hewan. Tujuan penelitian ini adalah untuk mengetahui jenis dan potensi Mollusca di zona pasang surut zona pasang surut tipe subtrat berbatu pantai Gatra Kabupaten Malang. Metode yang digunakan adalah transek kuadran. Penelitian ini dilakukan pada bulan Maret 2016 dengan 3 kali ulangan. Pada penelitian ini dihasilkan 20 jenis Gastropoda dan 6 jenis Bivalvia. Berdasarkan potensinya 4 diantaranya diketahui berpotensi sebagai sumber makanan (Angaria delphinus, Bulla ampulla, Conus ebraeus, Turbo bruneus), 5 berpotensi sebagai bahan baku hiasan (Engina mendicaria, Monetaria annulus, Monetaria caputserpentis, Monetaria moneta, Oxymeris dimidiata) dan 1 berpotensi sebagai sumber makanan dan bahan baku hiasan (Tridacna squamosa) serta lainnya belum diketahui potensinya. Selain itu hasil penelitian ini diharapkan menjadi masukan bagi tindakan pengelola berkaitan dengan pemanfaatan wilayah pesisir pantai Gatra secara optimal dan berkelanjutan.
Inventarisasi Jenis Arthropoda dan Echinodermata di Zona Pasang Surut Tipe Substrat Berbatu Pantai Gatra Kabupaten Malang Widiansyah, Arindra Trisna; Munzil, Munzil; Indriwati, Sri Endah
Jurnal Pendidikan: Teori, Penelitian, dan Pengembangan Vol. 1, No. 7
Publisher : citeus

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Abstract

Gatra beach is one of the ecotourism beach in Malang that have tidal zones with stone predominant substrate. Rocky substrate is the most crowded area makroorganismenya. Arthropods and Echinoderms have an important role in terms of food sources and ecologically. Given the lack of reporting types of Arthropods and Echinoderms in tidal zones Gatra Beach, the inventory of research done in this area. The aim of this study is inventory Arthropoda and Echinodermata. Results of this research is, overall found 14 species, 13 genera and 11 families of the phylum Arthropoda and Echinodermata.
Co-Authors Angrainy, Nunung Sonya Anis Anis Aprilia, Mega Aprilia, Pina Badaruddin, Moh Candra Ali Erna Wijayanti Handani, Mandha Frischa Haqqi Anajili Setyanto, Haqqi Anajili I Gusti Bagus Wiksuana Juliawan, Juliawan Lestari, Ririn Umi Munzil Nabila, Athaya Safa Ningrum, Rio Lina Setio Prasetyo, Dimas Wahyu Pratama, Theo Yolanda Racmawati, Trias Ismi Rahayu, Anita Budi Rahmatur Aji, Bagas Restu Megadiana Sukoco, Restu Megadiana Rizka Elan Fadilah, Rizka Elan Saiful Huda Sari, Desi Eka Sepfiana, Fifi SETYAWAN, BAGUS Sri Endah Indriwati Wahyuni, Fitri Dwi Yolanda, Maria Yunita, Winda Riska Zainul Mustofa, Zainul