Article Per Year (5 Year)
p-Index From 2021 - 2026
3.109
P-Index
This Author published in this journals
All Journal Indonesian Journal of Pharmaceutical Science and Technology Majalah Obat Tradisional JPSriwijaya Science and Technology Indonesia Jurnal Penelitian Sains Jurnal Ilmu Kefarmasian Indonesia Pharmacoscript Jurnal Ilmiah Farmako Bahari ad-Dawaa : Journal of Pharmaceutical Sciences Jurnal Abdi Insani Jurnal Mandala Pengabdian Masyarakat Jurnal Altifani Penelitian dan Pengabdian kepada Masyarakat Rafflesia Journal of Natural and Applied Sciences (RJNAS)
Dina Permata Wijaya
Department Of Pharmacy, Faculty Of Mathematics And Natural Sciences, Sriwijaya University Jl. Raya Palembang-Prabumulih Km. 32, Indralaya, Sumatera Selatan, 30662, Indonesia
Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Economics, Econometrics & Finance Education Energy Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences

Published : 22 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search
Journal : Pharmacoscript

 1 
OPTIMIZATION OF BUTTERFLY PEA EXTRACT PEEL-OFF MASK WITH VARIATIONS OF POLYVINYL ALCOHOL AND IOTA CARRAGEENAN USING FACTORIAL DESIGN Dina Permata, Wijaya; Shaum, Shiyan; Nabilah Putri, Hadiani; Herlina, Herlina; Mutia Sari, Wardana
Pharmacoscript Vol. 8 No. 1 (2025): Pharmacoscript
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat, Universitas Perjuangan Tasikmalaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36423/pharmacoscript.v8i1.1798

Abstract

ABSTRACT The butterfly pea flower (Clitoria ternatea) contains antioxidants that help combat premature skin aging. Peel-off masks are popular with consumers as topical formulations because they are unique and practical. An essential component of peel-off masks is the gelling agent Polyvinyl Alcohol (PVA), which acts as a film-forming agent. However, PVA at the wrong concentration can result poor mask physical properties. Combining PVA with other gelling agents can obtain peel-off masks with better physical properties. This study aims to identify the effect of PVA and iota carrageenan on the optimal formula of peel-off masks regarding physical properties, stability, and antioxidant activity. Butterfly pea flower extract was obtained by maceration in 70% ethanol. Optimization of PVA and iota carrageenan was conducted using a factorial design method, observing responses such as viscosity, spreadability, and drying time. Peel-off masks with butterfly pea flower extract were prepared with concentration variations of PVA (6%, 10%) and iota carrageenan (0.5%, 1%). The optimal formula was then tested for stability using cycling test method and for antioxidant activity using DPPH method. Increasing concentrations of PVA and iota carrageenan significantly affects viscosity, spreadability, and drying time, with a p-value < 0.05. The optimal peel-off mask formula contained 16% PVA and 0.5% iota carrageenan, with a viscosity of 16.473 cPs, spreadability of 5.6 cm, and drying time of 23 minutes and 11 seconds. The optimal formula demonstrated good stability during storage, with a significance p-value > 0.05, and was categorized as having weak antioxidant activity with an IC50 value 171.738 µg/mL.
HYPOGLYCEMIA POTENTIAL OF ETHANOL EXTRACT OF MELINJO LEAVES (Gnetum gnemon L.) ON WISTAR MALE WHITE RATS Herlina, Herlina; Dina Permata, Wijaya; Viva, Starlista; Annisa, Amriani; Herin, Noviarny
Pharmacoscript Vol. 8 No. 1 (2025): Pharmacoscript
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat, Universitas Perjuangan Tasikmalaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36423/pharmacoscript.v8i1.2011

Abstract

Male rats were used in the study to evaluate the ethanol extract of melinjo leaf (Gnetum gnemon L.) for hypoglycemia after being given alloxan and having their pancreatic histology observed. Secondary metabolites with antidiabetic properties found in melinjo leaf include flavonoids, tannins, saponins, and phenolics. This study sought to ascertain the ethanol extract of melinjo leaves' ED50 as well as its impact on lowering blood glucose levels and monitoring pancreatic histology. The doses of melinjo leaf ethanol extract were varied to 125, 250, and 500 mg/kgBW. An insulin dosage of 1 IU/kgBW served as the positive control, a 0.5% Na CMC suspension served as the negative control, and a normal control group did not receive any therapy. Rats were tested by utilizing a DTN-410-K photometer to measure their fasting blood glucose levels on days 0, 10, 15, and 20 using the GOD-PAP enzymatic method. Hematoxylin-eosin staining was used in histopathology preparations, which were prepared in accordance with established protocols. Melinjo leaf ethanol extract dosages of 125, 250, and 500 mg/kgBW resulted in three treatment groups with corresponding the percentage of blood glucose reduction (%BGR) of 31.48, 34.39, and 42.90%, whereas the positive control had an average BGR of 40.68%. Melinjo leaf ethanol extract has an ED50 of 720.86 mg/kgBW. According to the histological image, the positive control group and the three treatment groups showed improvement, whereas the negative group's Langerhans islet endocrine cells showed necrosis. The 500 mg/kg BW dosage group shows the greatest improvement.
Co-Authors Adik Ahmadi Amriani S, Annisa Angraeni, Via Annisa Amriani Annisa Amriani Annisa Haryati Annisa, Amriani Ayu Adelia Lestari Budi Untari Budi Untari Daniel Happy Putra Dian Wahyuni Elsa Fitria Apriani Fauziyah Filla Nur Oktriliansih Firana, Ario Firnando Firnando Fitrya . Fitrya Fitrya Herin, Noviarny Herlina Herlina Herlina Herlina Herlina Herlina Herlina Herlina Herlina Herlina Herlina Herlina Herlina Indah Solihah Khazanah Nurain Kovalina, Yosi Mardiyanto Mardiyanto Mardiyanto Mardiyanto Miksusanti Miksusanti Miksusanti Miksusanti Mustikasanti Mustikasanti Mutia Sari Wardana Nabilah Putri, Hadiani Najma Annuria Fithri Najma Annuria Fithri Najma Annuria Fitri Najmatul Asriah Novelia, Detri Novita, Rennie Puspa Puspa Ayu Pitayati Putri Siti Rahayu Regina Astryani Shaum Shiyan Starlista, Viva Sternatami Liberitera Veriza Agistin Vitri Agustiarini Viva Starlista Viva, Starlista