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All Journal Journal of Tropical Life Science : International Journal of Theoretical, Experimental, and Applied Life Sciences EKSAKTA : Jurnal Penelitian dan Pembelajaran MIPA Jurnal Basicedu TESLA: Jurnal Teknik Elektro Science Education and Application Journal Jurnal ABDINUS : Jurnal Pengabdian Nusantara Studies in Learning and Teaching BIOCHEPHY: Journal of Science Education Jurnal Basicedu JIPI (Jurnal IPA dan Pembelajaran IPA)
Fasih Bintang Ilhami, Fasih Bintang
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Economics, Econometrics & Finance Education Electrical & Electronics Engineering Energy Engineering Environmental Science Industrial & Manufacturing Engineering Mathematics Physics Social Sciences Other

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AKTIVITAS SISWA KELAS AKSELERASI SMP NEGERI 1 SIDOARJO MENJELANG SUMATIF AKHIR SEMESTER PADA MATA PELAJARAN IPA Mulyaningrum, Harnis Sekar; Erman, Erman; Ilhami, Fasih Bintang
Eksakta : Jurnal Penelitian dan Pembelajaran MIPA Vol 9, No 2 (2024): Eksakta : Jurnal Penelitian dan Pembelajaran MIPA
Publisher : Fakultas Keguruan Dan Ilmu Pendidikan, UM-Tapsel

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31604/eksakta.v9i2.273–279

Abstract

The purpose of this study is to explain the activities of accelerated class students and students who get the highest, medium, and lowest grades before the odd End of Semester Summative in science subjects. The type of research used is qualitative descriptive. This research involved targets, namely accelerated class students and 1 science teacher of JHS State of 1 Sidoarjo. The research instruments used were student response questionnaires, student response interviews, and teachers. The results showed that accelerated class student activities, namely learning carried out by 33 students, learning every day by 20 students, following tutoring by 21 students, studying with friends by 16 students, making a study schedule for 19 students, exercising by 4 students, participating in extracurricular activities by 7 students, participating in extracurricular activities outside school by 11 students, breakfast before the exam by 25 students,  33 students are in good physical condition, and 20 students are in a happy emotional state. The activities of accelerated class students who get the highest scores are not too dense. The activity of accelerated class students who get moderate grades is denser than students who get the highest grades. The activities of accelerated class students who get the lowest grades are not as dense as students who get the highest and lowest scores.
Penguatan Kompetensi Pedagogik Guru melalui Pelatihan Pembelajaran Inkuiri di Sanggar Bimbingan SIKL Malaysia Sari, Dhita Ayu Permata; Erman, Erman; Budiyanto, Mohammad; Mursyidah, Roihana Waliyyul; Ilhami, Fasih Bintang; Sabtiawan, Wahyu Budi
Jurnal ABDINUS : Jurnal Pengabdian Nusantara Vol 10 No 1 (2026): Volume 10 Nomor 1 Tahun 2026
Publisher : Universitas Nusantara PGRI Kediri

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29407/ja.v10i1.24288

Abstract

Quality education depends heavily on teachers' pedagogical competence. At Sanggar Bimbingan SIKL Malaysia, there is an urgent need to improve teachers' skills in implementing effective learning methods, particularly inquiry-based learning, in response to increasingly complex student learning challenges. This community service program involved a two-day inquiry-based learning training program, which included theory sessions, practical design sessions, and group discussions. Participants included 17 teachers currently working at Sanggar Bimbingan SIKL. Evaluation used tests to measure changes in their understanding and application of inquiry-based learning methods. The results of the activity showed that teachers were able to explore various sources of information to generate ideas for designing inquiry-based learning. Test results indicated that teachers' understanding and skills after the training were between 80 and 100. Furthermore, teachers responded positively to the training program, considering its content, usefulness, impact, motivation, and facilities and infrastructure. These findings demonstrate that the training was effective in positively impacting the pedagogical competence of Sanggar Bimbingan teachers.
Phytochemical Screening and In Silico Prediction of Gynura divaricata Ethanolic Extract as A Potential PIM-1 Inhibitor: Phytochemical and In Silico Prediction of Gynura divaricata Puspitarini , Sapti; Hermanto, Feri Eko; Rohim, Abd; Dliyauddin, Moh; Hendratmoko, Ahmad Fauzi; Budiyanto, Mohammad; Ilhami, Fasih Bintang
Journal of Tropical Life Science Vol. 16 No. 01 (2026)
Publisher : Journal of Tropical Life Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/jtls.16.01.06

Abstract

The pharmacological properties and traditional uses of medicinal plants often correlate with their bioactive constituents, which contribute to diverse therapeutic effects, including anticancer activity. Cancer remains one of the leading causes of mortality worldwide, and the discovery of novel anticancer agents from natural sources continues to be an important research focus. Gynura divaricata is a medicinal herb widely used in traditional Asian medicine for treating diseases. Recent studies have reported that G. divaricata contains several bioactive compounds. such as flavonoids, phenolic acids, terpenoids, and alkaloids, which are known for their antioxidant and anticancer properties. However, despite its traditional use and pharmacological potential, the molecular mechanisms underlying the anticancer activity of G. divaricata remain poorly understood. This study aimed to screen the phytochemical content of the ethanolic leaf extract of G. divaricata and to predict its potential anticancer activity through computational analysis targeting the PIM-1 protein. The DPPH inhibition, total flavonoid content, and total phenolic content of the extract were evaluated. Phytochemical profiling was performed using LC-HRMS. Molecular docking and molecular dynamics simulations were conducted to predict the interactions between the active compounds of G. divaricata and the PIM-1 protein. The extract exhibited 50% DPPH inhibition at a concentration of 2071.01 ppm, with total flavonoid and total phenolic contents of 107.44 ± 4.41 mg QE/g and 10.96 ± 0.49 mg GAE/g, respectively. Identified bioactive compounds, including curcumin, (+)-ar-turmerone, and 4-coumaric acid, were further analyzed through molecular docking to assess their interactions with the PIM-1 kinase. The docking results revealed that these compounds showed favorable binding affinities to the active site of PIM-1, suggesting their potential as anticancer agents. This study is the first to report the potential of G. divaricata active compounds as PIM-1 inhibitors, warranting further validation through both in vitro and in vivo studies.  
Co-Authors Ahmad Fauzi Hendratmoko Arbiana, Barika Arrayan, Hamdi Dliyauddin, Moh ERMAN ERMAN Fatimatuz Zahro Hermanto, Feri Eko Khasanah, Khilyah M Munasir MOHAMMAD BUDIYANTO Mulyaningrum, Harnis Sekar Mursyidah, Roihana Waliyyul Nadi Suprapto Prayogi, Ananda Puspitarini , Sapti Rohim, Abd Rohmah, Asna Aisiyah Lailatul Sari, Dhita Ayu Permata Sihombing, Rizky Agassy Uyuni, Qurrotul Wahyu Budi Sabtiawan Widodo*, Wahono Yuniswara, Riga Agnes ZAINUL ARIFIN IMAM SUPARDI