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All Journal Buletin Farmatera Majalah Patologi Indonesia Jurnal Pengabdian Pada Masyarakat METHABDI Majalah Ilmiah METHODA
Sanggam B. Hutagalung
Universitas Methodist Indonesia
Religion Agriculture, Biological Sciences & Forestry Computer Science & IT Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Physics Public Health

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Ekspresi Ki-67 dan HER-2/neu Berhubungan dengan Derajat Histopatologik Karsinoma Payudara Invasif No Special Type (NST) Sanggam B Hutagalung; I Ketut Mulyadi; I Gusti Alit Artha
Majalah Patologi Indonesia Vol 23 No 2 (2014): MPI
Publisher : Perhimpunan Dokter Spesialis Patologi Indonesia (IAPI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (401.438 KB)

Abstract

Background The role of Ki-67 and HER-2 /neu protein as a prognostic and predictive factor in invasive ductal breast carcinoma of no special type has been studied since the last decade. The aim of this study was to evaluate correlation between expression of Ki-67 and HER-2/neu with histopathological grade of invasive carcinoma of no special type breast. Methods This study was a cross-sectional study, which performed on paraffin embedded tissue of patients with invasive breast carcinoma of no special type who were diagnosed between Juli 2012 to September 2013. Histopathological grade was investigated by hematoxillin eosin and immunohistochemistry stain were made for Ki-67 and HER2/neu. Then the correlation between Ki-67 and HER-2/neu overexpression with histopathological grade tested by Spearman Correlation. Results We found 60 samples, mean age was 55 years old (range 28-71 years). According to histopathological grade of the tumor, we found cases of low grade were 29 cases (48.3%) and high grade were 31 cases (51.7%). There was significant positive correlation between Ki-67 overexpression and high histopathological grade of tumor r=0.650; p=0.000). There was significant correlation between HER-2/neu overexpression and high histopatho-logical grade of tumor (r=0.311; p=0.016). Conclusion It was concluded that the expression of Ki-67 and HER-2/neu have significant correlation with histopathological grade of invasive ductal breast carcinoma of no special type. Key words: HER-2/neu, histopathological grade, invasive ductal breast carcinoma no special type, Ki-67.
IMAGING OF MENINGIOMA Duma Ratna Sari Nasution; Ahmad Brata Rosa; Robert P Sinurat; Sanggam B Hutagalung
Buletin Farmatera Vol 5, No 3 (2020)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/bf.v5i3.3805

Abstract

Meningioma is one of the tumor in the brains that is extra-axial, which means it is not originated from  the brain cell. We report a case of a 60-year-old female, that was admitted to the emergency room (ER) of a secondary referral hospital, due to sudden weakness of upper and lower right extremities since 2 days prior. She had been experiencing a feeling of fullness in the left frontal head since the previous 3 months, along with some headache. She admitted to have had diabetes for the last 2 years. She also reported family history of brain tumor. Neurosurgeon has diagnosed the tumor as a meningioma with differential diagnose a metastatic tumor. A non contrast CT scan has found a meningioma. After being diagnosed, the patient underwent a craniotomy to remove the tumor. The histopathology finding confirmed the diagnosis of meningioma (WHO Grade I). Meningiomas are mostly hyperattenuating to surrounding brain parenchyma, while roughly one fourth are isodense. Overt calcification as in this case is usually seen in psammomatous and meningothelial. Well collaboration between clinician, radiologist, and histopathologist is the key to ensure patient’s recovery and safety
PENYULUHAN DAMPAK NARKOTIKA DAN OBAT TERLARANG KEPADA MASYARAKAT DESA LUMBAN PEA TIMUR, KABUPATEN TOBA Surjadi Rimbun; Agustina Veronika; Mawar G. Tarigan; Batara Simangunsong; Marlina Rajagukguk; Budi D. Sembiring; Edwin A. Pakpahan; Harry Butar-butar; Irene R. T. Damanik; Nasib M. Situmorang; Thomas Silangit; Donald F. Sitompul; Renatha N. H. Nainggolan; Sanggam B. Hutagalung; Titus Imanuel; Nur Azizah Ainun
Jurnal Pengabdian Pada Masyarakat METHABDI Vol 2 No 1 (2022): Jurnal Pengabdian Pada Masyarakat METHABDI
Publisher : Universitas Methodist Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (672.238 KB) | DOI: 10.46880/methabdi.Vol2No1.pp82-85

Abstract

Community Service (PkM) is carried out by the Faculty of Medicine Universitas Methodist Indonesia by providing counselling the effect of Narcotics and Drug abuse. PkM was held on 8-11 June 2022 at Lumban Pea Timur, Balige,Toba District, North Sumatera. The method used is to provide counselling/lectures and provide motivation, then followed by question and answer to obtain results and solutions as a form of solving problems and obstacles faced. The results of PkM with counselling are very effective considering that there are still many people who do not get information about Narcotics and Drug abuse. With this counselling, the public becomes aware of the Narcotics and Drugs abuse problem. Thus, it is hoped that the people of Lumban Pea Timur will aware and know how to prevent their community from Narcotics and drug abuse.
ALVEOLAR SOFT PART SARCOMA Sanggam B. Hutagalung; Jekson Martiar Siahaan
Majalah Ilmiah METHODA Vol. 8 No. 3 (2018): Majalah Ilmiah METHODA
Publisher : Universitas Methodist Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46880/methoda.Vol8No3.pp7-13

Abstract

Alveolar Soft Part Sarcoma (ASPS) is a rare sarcoma, this sarcoma accours around 0,2 – 0,9% of all soft tissue sarcomas. This tumour can occur at any age, but the peak incidence is in the age range of 15 – 35 years, rarely under the age of 5 years and after the age of 50 years. In adults, ASPS most often occur in deep soft tissues in the lower extremites, especially the anterior part of the thighs and buttocks. But in children and infants these tumours often occur in the area of the head and neck, especially the tongue and eyes. Tumours that occur in the head and neck are usually smaller in size may be due to earlier detection. Diagnostic of ASPS can be through CT – Scan/MRI examination, Fnab Citology, Histopathology, and Immunophenotype.
Co-Authors Agustina Veronika Ahmad Brata Rosa Batara Simangunsong Budi D. Sembiring Donald F. Sitompul Duma Ratna Sari Nasution Edwin Anto Pakpahan Harry Butar-butar I Gusti Alit Artha I Ketut Mulyadi Irene R. T. Damanik Mawar G. Tarigan Nasib M. Situmorang Nur Azizah Ainun Rajagukguk, Marlina Renatha N. H. Nainggolan Robert P Sinurat Siahaan, Jekson Martiar Surjadi Rimbun Thomas Silangit Titus Imanuel