Article Per Year (5 Year)
p-Index From 2021 - 2026
1.642
P-Index
This Author published in this journals
All Journal Jurnal Katalisator PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) JURNAL KESEHATAN PERINTIS Jurnal Farmasi Higea Jurnal Ilmiah Farmasi Farmasyifa Indonesia Natural Research Pharmaceutical Journal (INRPJ) Jurnal Pengabdian Masyarakat (ABDIRA) Jurnal Katalisator FASKES : Jurnal Farmasi, Kesehatan, dan Sains
Verawati
Universitas Perintis Indonesia
Aerospace Engineering Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Social Sciences Other

Published : 15 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 4 Documents
Search
Journal : Jurnal Katalisator

 1 
PENGARUH FRAKSI ETIL ASETAT DAUN PILADANG (Solenostemon scutellarioides (L) Codd) TERHADAP KADAR KOLESTEROL TOTAL TIKUS PUTIH JANTAN Verawati verawati; Mimi Aria; Iyun Julia Ningsih
Jurnal Katalisator Vol 2, No 1 (2017): KATALISATOR
Publisher : LLDIKTI Wilayah X

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (560.537 KB) | DOI: 10.22216/jk.v2i1.1726

Abstract

Hypercholesterolemia is a risk factor for atherosclerosis and vascular diseases. Medicinal plants with different content of secondary metabolites such as polyphenols and flavonoids are natural sources to cope hypercholesterolemia. This study aimed to determine the effect of ethyl acetate fraction of piladang leaves (Solenostemon scutellarioides (L) Codd) on serum cholesterol levels in hypercholesterolemic male rats. Rats were divided into 6 groups, each consisting of 6 animals: group I (negative control), group II (positive control), group III, IV and V were each given fraction of ethyl acetate doses respectively 100, 250 and 500 mg/kg and group VI (simvastatin as a comparator). Measurement of serum cholesterol levels were conducted with CHOD-PAP method using a photometer 5010. Result showed ethyl acetate fraction affects cholesterol levels of experimental animals with a lower value than the positive control. According to statistics of one way ANOVA followed by the Duncan test method SPSS 17 showed no significant differences (p> 0.05) on cholesterol levels in all given doses of ethyl acetate fraction. Group III(a dose of 100 mg / kg) was probably the most effective in lowering the blood cholesterol levels of experimental animals.
PENGARUH METODE EKSTRAKSI TERHADAP KADAR FENOLAT TOTAL DAN AKTIVITAS ANTIOKSIDAN DAUN SALAM (Syzygium polyanthum (Wight) Walp.) Verawati Verawati; Dedi Nofiandi; Petmawati Petmawati
Jurnal Katalisator Vol 2, No 2 (2017): KATALISATOR
Publisher : LLDIKTI Wilayah X

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (613.855 KB) | DOI: 10.22216/jk.v2i2.1744

Abstract

The research about influence of extraction method on phenolic content and antioxidant activity of Bay leaves (Syzygium polyanthum (Wight) Walp) has been conducted.  Extraction methods used were maceration, percolation and soxhletation with ethanol 70% used as solvent extraction.  Total phenolic level were determined by using Folin Ciocalteu method whereas antioxidant activity with DPPH radical scavenging method. . The highest extractive value was obtained from percolation method at 59.8% followed by maceration at 44.4% and soxhletation 22%. The highest levels of phenolic content was obtained from percolation (103,91mg/g), followed by soxhletation (72.80 mg/g) and maceration (69.76 mg/g). The antioxidant activity was shown by IC50 values, the percolation method amounted to 49.67 µg/ml; soxhletation 49.98 µg/ml and maceration 35.05 µg/ml. Based on the results of statistical analysis SPSS 17 using one-way ANOVA known that the extraction method significantly affect phenolic content and antioxidant activity of the extract of bay leaves.
STABILITAS ANTOSIANIN DARI KULIT TERONG BELANDA MERAH (Solanum betaceum Cav.) TERHADAP PH DAN SUHU Sandra Tri Juli Fendri; Verawati Verawati; Putri Saimi Nuras
Jurnal Katalisator Vol 5, No 1 (2020): KATALISATOR
Publisher : LLDIKTI Wilayah X

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22216/jk.v5i1.5023

Abstract

There had been identification and stability test of anthocyanin liquid extract from skin of eggplant of Holland that red colored using UV-Vis spectrophotometer. Anthocyanin is a color compound that responsible mostly red, blue and purple in fruit, vegetables and ornamental plants and these anthocyanins belong to the flavonoid group. Eggplans of Holland is taken from Tabing market, Padang City. The extraction process was performed by maceration method using solvent of 96% ethanol: HCl 1% (9:1). The identification of the anthocyanin compound on the sample extract was done by color reaction with 2 M NaOH and 2 M HCl. Stability of the anthocyanin pigment was tested by both the pH and temperature difference treatments. The pH used was pH 1, 3, 5, 7 and 9, while the temperature used was 30oC, 40oC, 60oC, 80oC and 100oC. The parameters of stability are the color of solution, maximum wavelength (λmax) and absorbance. The anthocyanin pigments stability test Eggplant of Holland was performed by using one-way of statistical data of variances (ANOVA), the liquid leather extract was stated stable at the influence of pH to temperature (temperature 30, 40, 60 and 80oC), especially at pH 1-3 next pH 5 and pH 7.Keywords : Anthocyanin, identification, pH, temperature, stability test
Profil Kimia dan Aktivitas Antioksidan Fraksi Air Terhidrolisis dari Daun Piladang (Solenostemon Scutellarioides) Verawati Verawati; Dira Dira; Dira Arieska
Jurnal Katalisator Vol 4, No 1 (2019): KATALISATOR
Publisher : LLDIKTI Wilayah X

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (748.46 KB) | DOI: 10.22216/jk.v4i1.3892

Abstract

Daun Piladang (Solenostemon scutellarioides) merupakan obat tradisional Sumatera Barat yang memiliki banyak kandungan metabolit sekunder berpotensi sebagai antioksidan. Metabolit sekunder seperti golongan fenolat yang terdapat pada fraksi polar umumnya terdapat dalam bentuk glikosida. Proses hidrolisis dapat memutuskan ikatan gula sehingga dapat melepaskan aglikon yang memiliki aktivitas antioksidan lebih tinggi daripada bentuk glikosidanya. Pada penelitian ini dilakukan hidrolisis asam terhadap fraksi air (polar) daun piladang, menggunakan asam asetat, asam fosfat dan asam klorida. Profil kimia fraksi hasil hidrolisis ditentukan secara kualitatif dengan KLT dan secara kuantitatif dengan metode Folin Ciocalteu untuk memperoleh kadar fenolat total.  Aktivitas antioksidan fraksi hasil hidrolisa diperiksa dengan metode perangkapan radikal DPPH. Hasil penelitian menunjukkan adanya perbedaan profil KLT dari masing-masing fraksi hasil hidrolisis. Kadar fenolat tertinggi diperoleh pada hidrolisis dengan asam fosfat yaitu 7,736 % diikuti asam klorida 4,218% dan asam asetat 2,024%. Aktivitas antioksidan tertinggi ditunjukkan pula oleh hasil hidrolisis dengan asam fosfat yaitu dengan IC50 413,92 ppm yang termasuk ke dalam kategori lemah.Piladang leaves (Solenostemon scutellarioides) is a traditional West Sumatra medicine which has a lot of secondary metabolite content which has the potential as an antioxidant. Secondary metabolites such as the phenolic group found in the polar fraction are generally in the form of glycosides. The hydrolysis process can break the bond of sugar so that it can release aglycone which has higher antioxidant activity than the form of glycosides. In this study,  the acid hydrolysis of the water fraction (polar) of piladang leaves was carried out using acetic acid, phosphoric acid and hydrochloric acid. The chemical profile of the hydrolysis fraction was determined qualitatively by TLC and quantitatively by the Folin Ciocalteu method to obtain total phenolic levels. The antioxidant activity of the hydrolysis fraction was examined by the DPPH radical scavenging method. The results showed a difference in the TLC profile of each hydrolysis fraction. The highest phenolic content was obtained by hydrolysis with phosphoric acid which was 7,736% followed by hydrochloric acid 4,218% and acetic acid 2,024%. The highest antioxidant activity was also shown by the results of hydrolysis with phosphoric acid, with IC50 413.92 ppm which was included in the weak category.
Co-Authors Almahdy Amilia Putri Arifah Nasir B.A. Martinus Bastian Nova Deddi Prima Putra Dedi Nofiandi Dira Arieska Dira Dira Dwi Fazillah Zalri Eka Fitrianda Elfionita, Yolla Sarni Febriyenti F. Fendri, Sandra Tri Juli Hanne Savera Intan Suci Mayasari Irma Juita, Atika Iyun Julia Ningsih Martinus BA Miftahur Rahmi Mimi Aria Nur ‘Azah Okta Fera Petmawati Petmawati Putri Saimi Nuras Rina Wahyuni Riska Ramadhani Siska Ferilda Tisa Mandala Sari Wardi, Epi Supri Zaunit, Muthia Miranda