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All Journal Journal of Tropical Life Science : International Journal of Theoretical, Experimental, and Applied Life Sciences PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat CAHAYA AKTIVA Jurnal Akuntansi, Manajemen dan Ilmu Ekonomi (JASMIEN) Generics: Journal of Research in Pharmacy Bukhori: Kajian Ekonomi dan Keuangan Islam Jurnal Pengabdian Masyarakat Bangsa Indonesian Economic Review Generics : Journal of Research in Pharmacy Medical Sains : Jurnal Ilmiah Kefarmasian
Kharisma Novita Sari
Faculty Of Economics And Islamic Business, UIN Sayyid Ali Rahmatullah Tulungagung, Tulungagung
Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Energy Environmental Science Health Professions Industrial & Manufacturing Engineering Law, Crime, Criminology & Criminal Justice Mathematics Medicine & Pharmacology Nursing Physics Public Health Social Sciences

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Performance Comparison of Mutual Funds and Sharia Mutual Funds Kharisma Novita Sari; Moch Sulchan; Mimah Mutamimah
Bukhori: Kajian Ekonomi dan Keuangan Islam Vol 1 No 1 (2021): Juli
Publisher : Penerbit Goodwood

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35912/bukhori.v1i1.600

Abstract

Purpose: This study aimed to examine the differences in the performance of Islamic mutual funds with mutual funds based on the Sharpe and Jensen method for the 2010-2020 periods in the Indonesian capital market. Research Methodology: The study uses a quantitative approach to the type of comparative research. The data used is secondary data from Otoritas Jasa Keuangan (OJK). The population used in this study is the capitalization of sharia mutual fund performance data with mutual funds, the periods 2010-2020 (monthly data) in the Indonesian capital market. Data analysis was carried out using the Sharpe and Jensen method and the Manova test with the help of the SPSS statistical program. Results: The results of this study indicate that there is no significant difference between the performance of Islamic mutual funds and mutual funds with the Sharpe and Jensen method. This shows that the return on the performance of Islamic mutual funds and mutual funds based on the Sharpe and Jensen method received will be relatively the same. Investment performance in mutual fund portfolio management is reflected in the Net Asset Value (NAV). Conclusions: The results show no significant difference in the performance of Islamic and conventional mutual funds, as measured by the Sharpe and Jensen methods. This indicates that returns from both types of funds are relatively similar, and investment performance, reflected in Net Asset Value (NAV), is influenced by the manager’s policies and strategies. Limitations: This research has been attempted and carried out in accordance with scientific procedures. However, it still has limitations; this research is limited to 2010 – 2020 with monthly data. Contributions: This research implies that this research can better contribute to the general public, academics, and investors to understand the performance of capital market investment instruments before they invest.
Comparison of Performance of Stock and Sharia Stock Kharisma Novita Sari; Debi Maenadi; Mimah Mutamimah; Maya Zulfa Maslihatin
Indonesian Economic Review Vol. 2 No. 2 (2022): August : Indonesian Economic Review
Publisher : Cahaya Abadi Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53787/iconev.v2i2.15

Abstract

The purpose of this study was to examine the differences in the performance of Islamic stocks with stocks based on the Sharpe and Jensen method for the 2010-2020 period in the Indonesian Capital Market. The research method is using a quantitative approach with the type of comparative research. The data used is secondary data from OJK. The population used in this study is the capitalization of sharia stock performance data compared to stocks, for the 2010-2020 period (monthly data) in the Indonesian Capital Market. Data analysis was carried out using the Sharpe and Jensen method and the Manova test with the help of the SPSS statistical program. The results of this study indicate that the performance of Islamic stocks with stocks has a significant difference and the performance of Islamic stocks is better than stocks based on the Sharpe and Jensen method. This shows that the return on the performance of sharia shares with shares based on the Sharpe and Jensen method that will be received will be relatively different. The implication of this research is that this research can contribute to the general public, both academics, investment players and the general public so that they better understand the performance of capital market investment instruments before they invest.
In Silico Drug Discovery Identifies Stigmasterol from Red Betel (Piper crocatum Ruiz & Pav) Stem as a Potential Antidiabetic Agent Sari, Putri Kharisma Novita; Febyaningrum, Vitasigi Dwi
Journal of Tropical Life Science Vol. 16 No. 2 (2026)
Publisher : Journal of Tropical Life Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/jtls.16.02.02

Abstract

Type 2 diabetes (T2DM) is a metabolic disorder caused by insufficient insulin secretion and the inability of tissues to respond to insulin. Therapy can include the use of insulin in conjunction with other glucose-lowering agents, but these drugs have several limitations related to efficacy, tolerability, and potential side effects. The use of herbal medicines has begun to develop as a therapeutic option, including stigmasterol. Stigmasterol, which has been successfully isolated from several plants, has demonstrated antidiabetic activity in both in vivo and in vitro studies. This study aimed to conduct a comprehensive exploration of the potential, mechanism of action, protein targets, and profile of stigmasterol found in red betel stem as a candidate natural antidiabetic agent in silico. The results of this study indicate that stigmasterol has potential as a drug candidate for the therapy of T2DM with a predicted limited level of toxicity. Computational analyses suggest that stigmasterol may possess therapeutic potential against T2DM by regulating biological processes associated with insulin resistance and the AMPK signaling pathway, potentially through interactions with the key targets STAT3, AKT1, NFKB1, HMGCR, MTOR, and ACACA. Both ligand-based (Support Vector Machine regression) and structure-based (molecular docking) approaches show promising results regarding the activity of this compound. Therefore, stigmasterol is predicted as a potential candidate for further development as a natural antidiabetic agent through the multitarget mechanism of action generated from this modeling. However, the pharmacokinetic profile of stigmasterol indicates potential challenges in meeting drug-likeness criteria, which require further experimental validation.
Co-Authors Astuti, Rini Budi Dea Tachta Almira Debi Maenadi Eny Agustin Nur Aeni Fatimi, Hana Anisa Febyaningrum, Vitasigi Dwi Feni Krismawati Fauziah Hadi , Saptono Imam Prabowo, Imam Larasati, Rizky Dwi Lia Puspitasari Mahendra, Raihan Bintang Maya Zulfa Maslihatin Mimah Mutamimah Mimah Mutamimah Mimah Mutamimah Moch Sulchan Moch Sulchan Nugraha, Akbar Eka Pribadi, Fitrawan Hernuza Saptono Hadi, Saptono Tamimah, Rifqah Alya Usmarini, Razita Fathya