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All Journal International Journal of Public Health Science (IJPHS) Media Farmasi : Jurnal Ilmu Farmasi (Journal Of Pharmaceutical Science) Acta Pharmaciae Indonesia : Acta Pharm Indo JCPS (Journal of Current Pharmaceutical Sciences) Lumbung Farmasi : Jurnal Ilmu Kefarmasian Jurnal Insan Farmasi Indonesia Bioscientist : Jurnal Ilmiah Biologi Medical Sains : Jurnal Ilmiah Kefarmasian Jurnal Pengabdian Masyarakat Bangsa Jurnal Farmasi Indonesia Borneo Journal of Pharmacy Medical Sains : Jurnal Ilmiah Kefarmasian Jurnal Sains dan Kesehatan
Nashihah, Siti
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Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Economics, Econometrics & Finance Education Energy Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Nursing Physics Public Health Social Sciences

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Journal : Jurnal Farmasi Indonesia

 1 
UJI DAYA HAMBAT EKSTRAK ETANOL DAUN RAMBAI (Sonneratia Caseolaris (L) Engl) TERHADAP BAKTERI Propionibacterium acnes DAN Staphylococcus epidermidis Fitriani, Tiya; Nashihah, Siti
JFIOnline | Print ISSN 1412-1107 | e-ISSN 2355-696X Vol. 13 No. 1 (2021): Jurnal Farmasi Indonesia
Publisher : Pengurus Pusat Ikatan Apoteker Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (488.714 KB) | DOI: 10.35617/jfionline.v13i1.65

Abstract

Currently there are many anti-acne preparations on the market but not a few of these drugs give side effects to the user. The need for alternatives from nature that can act as antibacterial in the treatment of acne that has a smaller risk of side effects. This study aims to determine the inhibition of ethanol extract of rambai leaves (Sonneratia caseolaris (L) Engl) against acne-causing bacteria Propionibacterium acnes and Staphylococcus epidermidis. Extraction was carried out by the UAE method and a yield of 9.21% was obtained. Phytochemical screening obtained positive results containing flavonoids, triterpenoids, tannins, saponins and phenol compounds. Antibacterial activity test was conducted using the well diffusion method with 4 different concentrations of 15%, 25%, 50% and 75% with positive control of clindamycin 0.03% and negative control of DMSO 1%. The results of antibacterial activity testing on Propionibacterium acnes bacteria obtained inhibition zone diameters of 3.3 mm; 4.43 mm; 6.48 mm; and 8.45 mm, respectively, while on Staphylococcus epidermidis bacteria 11.08 mm; 12.27 mm; 15.38 mm; and 16.78 mm, respectively. The results of the One Way ANOVA statistical test obtained a significance value of 0.000 (p<0.05) which indicates that the treatment of each group is significantly different.
Uji Aktivitas Antibakteri Ekstrak Daun Karamuntin (Rhodomyrtus tomentosa (Aiton) Hassk.) terhadap Bakteri Streptococcus mutans Ramadhanty, Dewi Alfisyah; Lestari, Yulianita Pratiwi Indah; Nashihah, Siti
JFIOnline | Print ISSN 1412-1107 | e-ISSN 2355-696X Vol. 15 No. 1 (2023): Jurnal Farmasi Indonesia
Publisher : Pengurus Pusat Ikatan Apoteker Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (858.701 KB) | DOI: 10.35617/jfionline.v15i1.112

Abstract

Abstract: Indonesia has many medicinal plants that can used to treat various diseases. One of the plants is the leaves of karamunting (Rhodomyrtus tomentosa (Aiton) Hassk.). Traditionally, karamunting leaves are used as a treatment in dental caries, wound care, and scabies. This study was aimed to determine the antibacterial effect of karamunting leaves ethanol extract against Streptococcus mutans by the well method. The design of this study was experimental laboratory research. The sample was karamunting leaves ethanol extract. The extracts were evaluated for antibacterial activity against Streptococcus mutans using the well method with a concentration of 6,25%; 12,5%; 25%; and 50% w/v. The result showed karamunting leaves ethanol extract provided an antibacterial activity against Streptococcus mutans with an inhibition zone diameters of 17,7±0,0577; 22,6±0,2516; 25,3±0,1527; and 28,3±0,0577 mm. at the concentration of 6,25% w/v, 12,5% w/v, 25% w/v, and 50% w/v, respectively. karamunting leaves ethanol extract had significant antibacterial activity against Streptococcus mutans at the concentration 50% w/v with inhibition zone diameters of 28,3 mm.
Co-Authors Ahmad Mahdi Mar'ie Ahsana, Dina Andika Andika Andika Andika Andika Andika Atunnisa, Waro Damayanti, Indira Diah Safitri Dina Ahsana Dwi Utami Fajeriyati, Nurul Fitriah Fitriah Fitriani, Tiya Helma Novitasari Islan Nor Khairunnisa Khairunnisa Mahmudah Mahmudah Mar'ie, Ahmad Mahdi Maulana, Rafli Monica, Cahya Muhammad Yusron Maulana El-Yunusi Muliyati, Imas Murdi, Habib Basyanur Mustofa Ahda Nurkhasanah Mahfudh Ramadhanty, Dewi Alfisyah Rizka Mulya Miranti rizki rahmadi Rizqiannoor, Muhammad Sabilla, Giriani Ayu Siti Napisah Siti Rahmita Syifa Noorwina Ulpah, Rusmili Wandi, Halifah Risma Wardana, Kevin Febrian Waro Atunnisa Yulianita Pratiwi Indah Lestari Yulisa, Ika Zamzani, Irfan Zamzani, Irfan