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All Journal Qanun Medika - Medical Journal Faculty of Medicine Muhammadiyah Surabaya Herb-Medicine Journal MAGNA MEDICA: Berkala Ilmiah Kedokteran dan Kesehatan Medical and Health Science Journal Jurnal Pendidikan Indonesia (Japendi)
Marlina, Uning
Universitas Muhammadiyah Surabaya, Indonesia
Biochemistry, Genetics & Molecular Biology Education Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Public Health Social Sciences

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THE EFFECT OF CITICOLIN IN MOTORIC IMPROVEMENT OF ACUTE ISCHEMIC STROKE PATIENTS IN SITI KHODIJAH SEPANJANG HOSPITAL Dza’wan Maula Iwanatud Diana; Laily Irfana; Yelvi Levani; Uning Marlina
Jurnal Ilmu Kesehatan dan Kesehatan Vol 4 No 2 (2020): AUGUST
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/mhsj.v4i2.1579

Abstract

Background: According to WHO, stroke is the leading cause of morbidity and the second cause of death with a mortality rate of around 5.54 million. Stroke, based on its etiology, consists of ischemic and hemorrhagic. Ischemic stroke is caused by a blockage in the blood-brain, whereas hemorrhagic stroke occurs due to the rupture of brain blood vessels. Based on the pathophysiology of ischemic stroke, its therapy consists of thrombolytic in thrombus for brain reperfusion and anticoagulants or antiplatelet in strokes due to embolization because it is grown in a collateral-containing lavatory and neuroprotectant assistance to trace cytotoxic nerves. Neuroprotectants that are often used are piracetam and citicoline. Citicoline improves neuronal cell membranes by increasing synthesis of the main component of cell membranes, phosphatidylcholine, then repaired neuronal cell membranes. Objective: To find out motor improvement in stroke patients at Siti Khodijah Sepanjang Hospital by giving 500mg of citicoline per day orally for 5 days. Methods: A case-control observational analytic study using medical record data. Consists of a group with standard therapy, antiplatelets, and another group with 500mg/day antiplatelet and citicoline therapy for 5 days. Patients were examined for MRC motor on the first day and the fifth day. Results: The statistical test used the Chi-Square test  and wilcoxon test with a significance value of 0.00 and 0,01 (<0.05). Conclusion: obtained significant motor improvement in stroke patients 500mg/day for 5 days at Siti Khodijah Sepanjang Hospital.   Latar belakang: Menurut WHO stroke menjadi penyebab utama morbiditas dan sebab kematian nomor dua dengan angka kematian sekitar 5,54 juta. Stroke berdasarkan etiologinya diklasifikasikan menjadi stroke iskemik dan stroke hemoragik. Stroke iskemik merupakan stroke yang diakibatkan oleh adanya sumbatan pada pembuluh darah di otak sedangkan stroke hemoragik akibat adanya pecahnya pebuluh darah otak. Berdasarkan patofisiologinya terapi stroke iskemik terdiri dari trombolitik pada iskemik akibat trombus untuk reperfusi otak dan antikoagulan atau antiplatelet pada stroke akibat emboli sebagai pencegahan terbentuknya trombus pada pembuluh darah kolateral serta pemberian neuroprotektan untuk menghambat penyebaran kerusakan neuroglia pada penumbra akibat proses sitotoksik. Neuroprotektan yang sering digunakan adalah pirasetam dan citicolin. citicolin berfungsi memperbaiki membran sel neuron dengan meningkatkan sintesis komponen utama membran sel yaitu phosphatidylcholine sehingga terjadi peningkatan perbaikan membran sel neuron. Tujuan: Untuk mengetahui perbaikan motorik pada pasien stroke iskemik akut di RS Siti Khodijah Sepanjang. Metode: Jenis penelitian analitik observasional case-control bersifat retrospektif menggunakan data rekam medis. Terdiri dari kelompok dengan terapi standar yaitu antiplatelet dan kelompok lain dengan terapi antiplatelet dan citicolin 500mg/hari selama 5 hari. Pasien dilakukan pemeriksan motorik MRC di hari pertama dan hari kelima. Hasil: Uji statistik menggunakan uji Chi-Square dan uji wilcoxon dengan nilai signifikansi masing-masing 0,00 dan 0,01 (<0,05). Kesimpulan: didapatkan perbaikan motorik yang signifikan pada pasien stroke iskemik akut dengan pemberian citicoline 500mg/hari selama 5 hari di Rumah Sakit Siti Khodijah Sepanjang.
Anatomical and Sexual Functions at Post Neovagina operation on Mayer Rokitansky Kuster Hauser Syndrome (MRKH) Patients with Sigmoid ,Amnion and Conventional Methods in Dr. Soetomo Hospital Uning Marlina; Hari Parathon; Azami Demas; Jimmy Yanuar; Iwan Kristian
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 4, No 1 (2020)
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1155.232 KB) | DOI: 10.30651/jqm.v4i1.3639

Abstract

 ABSTRACT Background: The Mayer–Rokitansky–Kuster–Hauser (MRKH) syndrome is congenital malformation due to utero‐vaginal agenesis. For many years Dr Soetomo Hospital has been applying McIndoe technique using biomaterial amnion. Recently, in collaboration with digestive surgery, neovagina operation using sigmoid was performed. However, no data are available on the complications, anatomic, and functional results of the neovagina operation using sigmoid and amnion. Methods: MRKH patients who have performed neovagina operations from January 2011 to December 2014 were involved in this case review. The anatomical function was measured based on minimal vaginal length of more than 6 cm and width of 3 cm, while sexual performance is measured by Female Sexual Function Index (FSFI), which is above 23, and Female Sexual Distress Score Revised (FSDSR), whose score is < 11. Result: In 4 years period, there were 6 cases of MRKH underwent neovagina (1 used sigmoid and 5 used amnion) at Dr Soetomo Hospital. All of them had a satisfying anatomical and sexual function. Even though neovagina operation significantly reduces sexual distress, but it does not necessarily mean alleviate as seen by the high FSDSR score. Neovagina using amnion has faster operation time and cheaper with the same length of hospital stay than sigmoid neovagina. Sigmoid neovagina has a better vaginal length, lubrication and no need dilatation after operation, but it has higher complication risk. Conclusion: The Neovagina technique should be used at Soetomo Hospital depends on patient wishes and circumstances. For those who have strong financial support and are not willing to do manual dilatation, they should use the sigmoid neovagina, while those who are able to do manual dilatation, then the amnion neovagina is a good choice.Keywords: Neovagina, MRKH, sigmoid, amnion, anatomic function 
Hubungan Faktor Internal Dan Eksternal Akseptor Terhadap Kepatuhan Akseptor Kontrasepsi Suntik Khofifah Dwi Oktaviana; Muhammad Anas; Ninuk Dwi Ariningtyas; Uning Marlina
Herb-Medicine Journal: Terbitan Berkala Ilmiah Herbal, Kedokteran dan Kesehatan Vol 5, No 1 (2022): Herb-Medicine Journal Januari 2022
Publisher : Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/hmj.v5i2.9953

Abstract

The population of Indonesian continues to increase, while the total fertility rate is not yet on target. So that an effective family planning program is needed to reduce Indonesia's population growth. Injection contraceptive acceptor adherence is needed to maximize family planning programs for a better future. Objective: to analyze the relationship between age, education, knowledge, work status, and support from husbands of injection contraceptive acceptors in women of childbearing age to compliance with re-injection visits. The study was using an analytical observational, cross-sectional study design. The sampling technique was non-random sampling purposive sampling, a sample size of 96 people, a questionnaire was used to collect data and data analysis using the chi-square test. Results: The number of adherent injecting contraceptive acceptors was 57.3%. The results showed that the variables associated with injection visit compliance were age (p = 0.022), knowledge (p = 0.005), and work status (p = 0.017). Meanwhile, the variables not related to compliance with injection visits were education (p = 0.172), husband's support (p = 0.833) and the number of children (p=0.167). Conclusion: There is a relationship between age, knowledge, and work status on the compliance of injection contraceptive acceptor visits.  Jumlah penduduk indonesia terus mengalami peningkatan, sedangkan total fertility rate belum sesuai target. Sehingga diperlukan program keluarga berencana yang efektif untuk menurunkan pertumbuhan penduduk indonesia. kepatuhan akseptor kontrasepsi suntik sangat diperlukan untuk memaksimalkan program keluarga berencana demi masa depan yang lebih baik. Tujuan : menganalisis hubungan usia, pendidikan, pengetahuan, status bekerja, dan dukungan suami akseptor kontrasepsi suntik pada wanita usia subur terhadap kepatuhan melakukan kunjungan suntik ulang. Jenis penelitian yang digunakan dalam penelitian ini yaitu analitik observasional desain Cross-sectional study. Teknik samplingnya menggunakan  non random sampling - purposive sampling, besar sampel 96 orang, kuesioner digunakan untuk mengumpulkan data dan analisis data menggunakan uji chii square. Hasil: Jumlah akseptor kontrasepsi suntik yang patuh yaitu sebesar 57,3%. Hasil penelitian diperoleh bahwa variabel yang berhubungan dengan kepatuhan kunjungan suntik yaitu usia (p=0,022), pengetahuan (p=0,005), dan status bekerja (p=0,017). Sedangkan variabel yang tidak berhubungan dengan kepatuhan kunjungan suntik yaitu pendidikan (p=0,172), dukungan suami (p=0,833), dan jumlah anak (p=0,167). Kesimpulan: Terdapat hubungan antara usia, pengetahuan, dan status bekerja terhadap kepatuhan kunjungan akseptor kontrasepsi suntik.
Pengaruh Penerapan Diet Rendah Glikemik Pada Perubahan Manifestasi Klinis Dan Penanda Inflamasi Wanita Dengan Polycystic Ovary Syndrome (PCOS) Syafa Danissa Maulitanti; Uning Marlina; Yudith Annisa Ayu Rezkitha; Dewi Masitha
Jurnal Pendidikan Indonesia Vol. 4 No. 05 (2023): Jurnal Pendidikan Indonesia (Japendi)
Publisher : Publikasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59141/japendi.v4i05.1838

Abstract

Polycystic Ovary Syndrome (PCOS) adalah gangguan hormonal pada wanita. Sebanyak 38-88% wanita PCOS diseluruh dunia memiliki berat badan berlebih, dan diet dapat merubah gejala klinis dan penanda inflamasi pada wanita PCOS. Melalui telaah literature ini akan menyampaikan hasil pengkajian terhadap pengaruh penerapan diet rendah glikemik pada perubahan manifestasi klinis dan penanda inflamasi wanita dengan polycystic ovary syndrome (PCOS). Penulisan literature review ini mengumpulkan dan menganalisis artikel-artikel penelitian yg dicari menggunakan format free full text, dari tahun 2012 s.d. 2023, dengan platform Google Schoolar, Bahasa Indonesia dan Inggris, dan menggunakan kata kunci; Low glycemic index diet, polycystic ovary syndrome, body mass index, menstruation, pregnancy, inflammatory markers. Didapatkan 20 jurnal yang berkaitan dengan kata kunci tersebut. Terdapat perubahan manifestasi klinis dan penanda inflamasi pada wanita dengan PCOS setelah melakukan diet rendah indkes glikemik. Penurunan indeks massa tubuh pada wanita PCOS mulai terjadi pada minggu ke-12 s.d. 27  setelah melakukan diet rendah indeks glikemik. Menstruasi pada wanita PCOS mulai terjadi pada minggu ke-12 s.d. 24 setelah melakukan diet rendah indeks glikemik. Kehamilan pada wanita PCOS mulai terjadi pada minggu ke-8 s.d. 32 setelah melakukan diet rendah indeks glikemik. Penurunan kadar CRP, IL-6, dan TNF-α pada wanita PCOS mulai terjadi pada minggu ke-10 s.d. 12 setelah melakukan diet rendah indeks glikemik. Penerapan diet rendah glikemik berpengaruh pada perubahan manifestasi klinis dan penanda inflamasi wanita dengan PCOS.
Pengaruh Penerapan Diet Anti Inflamasi Pada Perubahan Manifestasi Klinis Dan Penanda Inflamasi Wanita Dengan Polycystic Ovary Syndrome (PCOS) Uning Marlina; Syafa Danissa Maulitanti; Yudith Annisa; Dewi Masitha
Jurnal Pendidikan Indonesia Vol. 4 No. 05 (2023): Jurnal Pendidikan Indonesia (Japendi)
Publisher : Publikasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59141/japendi.v4i05.1821

Abstract

Banyaknya angka kejadian wanita Polycystic Ovary Syndrome (PCOS) yang memiliki berat badan berlebih (38-88% wanita) menyebabkan salah satu terapi dari PCOS ialah dengan mengubah cara hidupnya dengan diet. Diet mampu mengubah bmi, manifestasi klinis, dan penanda inflamasi pada wanita PCOS. Peradangan kronik tingkat rendah dapat terjadi pada obesitas. Penderita PCOS dengan obesitas juga dapat terjadi peradangan ini. Oleh karena itu, mengontrol jalur inflamasi pada wanita dengan PCOS melalui diet antiinflamasi adalah salah satu caranya. Melalui telaah literature ini akan menyampaikan hasil pengkajian terhadap pengaruh penerapan diet anti inflamasi pada perubahan manifestasi klinis dan penanda inflamasi wanita dengan polycystic ovary syndrome (PCOS). Jenis literature yang ini ialah narrative literature review, database yang digunakan untuk mencari sumber yaitu PubMed, Research Gate, dan Google Scholar menggunakan kata kunci. Hasil pencarian artikel tersebut dibatasi dari tahun 2012–2023 menggunakan free full text bahasa inggris. Berdasarkan hasil review article, makanan yang sangat disarankan untuk diet antiinfamasi ini ialah makanan yang mengandung kaya akan antioksidan. Penerapan diet antiinflamasi pada perubahan manifestasi klinis dan penanda inflamasi wanita dengan PCOS berpengaruh dalam menurunkan BMI, mengembalikan siklus menstruasi, menyebabkan kehamilan spontan, dan menurunkan penanda inflamasi.
Relationship between Pregnant Woman Obesity Grade-1 and Grade-2 with The Incidence of Preeklampsia Mochammad Ilham, Ananda Frifiyant; Ariningtyas, Ninuk Dwi; Mochtar, Nur Mujaddidah; Marlina, Uning
MAGNA MEDICA Berkala Ilmiah Kedokteran dan Kesehatan Vol 9, No 2 (2022): August
Publisher : Universitas Muhammadiyah Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26714/magnamed.9.2.2022.89-95

Abstract

Background: Preeclampsia is a hypertensive disorder that can increase maternal and fetal morbidity and mortality during pregnancy. Pregnant women with obesity are at higher risk of preeclampsia.Objective: To prove the relationship between pregnant women with grade-1 and grade-2 obesity and the incidence of preeclampsiaMethod: This study used the design of a prospective cohort. The population was pregnant women with obesity who got check-ups in Pregnancy Unit at Wiyung Sejahtera Hospital in Surabaya. This study used a consecutive sampling technique. The samples were pregnant women with BMI ≥ 25 with 34-38 weeks gestational age who signed the consent form. The data were analyzed through the Chi-Square test.Result: The results show that respondents who do not experience preeclampsia are dominated by pregnant women with grade-1 obesity by 70% and grade-2 obesity by 30%. Meanwhile, those who experience preeclampsia are dominated by pregnant women with grade-2 obesity by 75% and grade-1 obesity by only 25%. The results of the Chi-Square test analysis obtain a p-value of 0.007 with an odds ratio of 7,000.Conclusion: Pregnant women classified as grade-2 obesity have a seven times greater risk of experiencing preeclampsia compared to pregnant women with grade-1 obesity.
Differences Characteristics of Partial Bowel Obstruction and Total Bowel Obstruction in Ileus Patients at Dr. Soegiri Lamongan Hospital Nisa, Syeila Ainun; Finansah, Yohni Wahyu; Marlina, Uning; Rochman, Syaiful
MAGNA MEDICA Berkala Ilmiah Kedokteran dan Kesehatan Vol 8, No 1 (2021): February
Publisher : Universitas Muhammadiyah Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (81.562 KB) | DOI: 10.26714/magnamed.8.1.2021.29-34

Abstract

Background: Across all age ranges, one in a thousand people is diagnosed with ileus annually. Ileus is categorized into two types, obstructive ileus, and paralytic ileus. Obstructive ileus is a condition where intestinal passage disorder occurs as a result of a mechanical blockage. There are 7,024 obstructive ileus without hernia in Indonesia and 7,059 paralytic ileus cases in 2004.Objective: To understand the comparison of characteristics of obstructive ileus patients.Method: This analytic descriptive research use the cross-sectional method. Samples are diagnosed with ileus based on the laparotomy result from RSUD Dr. Soegiri, Lamongan. The sampling method is total sampling based on 2015-2019 data. The samples were also using secondary data from medical records, from December 2019 to January 2020.Result: Respondents are mostly male with ages 65 years and over, less than ten days treatment duration, 39 minutes in the average length of partial bowel obstruction surgery duration, 42 minutes in the average length of total bowel obstruction surgery duration, less than two days treatment duration before surgery, percentage of ICU admission as high as 51.5 %, and blood transfusion percentage on 6.1%.  There are significant differences in the characteristics of ileus patient’s age (p-value 0,021).Conclusion: Based on this study, it can be concluded that there are differences based on age in the characteristics of partial bowel obstruction and total bowel obstruction on ileus patients, whereas gender, treatment duration, treatment duration before surgery, and surgery duration did not deliver any differences.
The Relationship Between The Level of Mother’s Breastfeeding Knowledge With Exclusive Breastfeeding Practice in The Center of Public Health Kenjeran Husnayain, Zida Shofy; Nurida, Annisa; Marlina, Uning; Prahasanti, Kartika
MAGNA MEDICA Berkala Ilmiah Kedokteran dan Kesehatan Vol 8, No 1 (2021): February
Publisher : Universitas Muhammadiyah Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (364.879 KB) | DOI: 10.26714/magnamed.8.1.2021.1-9

Abstract

Background: Exclusive breastfeeding is giving breast milk exclusively from newborns to 6 months of age without giving any food. Exclusive breastfeeding is essential for optimal baby growth and development, contains various essential nutrients for babies. In 2018 the coverage of exclusive breastfeeding in Indonesia still reached 65.16%, and the coverage of breastfeeding in East Java itself was still below the target of 76.98%. The low level of exclusive breastfeeding is still a problem because it can cause the baby's immune system to become lower, indigestion and illness risk in the baby is more generous to target.Objective: To determine the relationship between mothers' level of knowledge about breastfeeding and exclusive breastfeeding at Kenjeran Primary Health Center.Methods: This observational analytic study with a cross-sectional study design. The sampling technique was using the purposive sampling technique. Respondents in this study were mothers who had babies 6-24 months. The data collection process was directly asked through a questionnaire and analyzed using the contingency coefficient test.Results: This study involved 51 mothers who gave exclusive breastfeeding and 51 mothers who did not. The results showed that most of the respondents who breastfed and did not have the right knowledge level. Based on the contingency coefficient test results, it was found that there was no relationship between the level of mother's knowledge about breast milk to give exclusive breastfeeding at the Kenjeran Primary Health Center (the value of p = 0.251).Conclusion: There is no relationship between mothers' level of knowledge about breastfeeding and exclusive breastfeeding at the Kenjeran Primary Health Center.
Co-Authors Annisa Nurida Ariningtyas, Ninuk Dwi Azami Demas Dewi Masitha Dza’wan Maula Iwanatud Diana Finansah, Yohni Wahyu Hari Parathon Husnayain, Zida Shofy Iwan Kristian Jimmy Yanuar Kartika Prahasanti Khofifah Dwi Oktaviana Laily Irfana, Laily Mochammad Ilham, Ananda Frifiyant Muhammad Anas Ninuk Dwi Ariningtyas Nisa, Syeila Ainun Nur Mujaddidah Mochtar Rochman, Syaiful Syafa Danissa Maulitanti Yelvi Levani Yudith Annisa Yudith Annisa Ayu Rezkitha