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All Journal Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) JURNAL FARMASIMED (JFM) Majalah Farmasetika Lumbung Farmasi : Jurnal Ilmu Kefarmasian Community Empowerment Journal of Fundamental and Applied Pharmaceutical Science Media Farmasi Medical Sains : Jurnal Ilmiah Kefarmasian JPEMAS: Jurnal Pengabdian Kepada Masyarakat
ELASARI DWI PRATIWI, ELASARI DWI
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Arts Humanities Biochemistry, Genetics & Molecular Biology Chemistry Education Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health Social Sciences

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Formulasi Krim Deodoran-Anti perspiran Alami yang Mengandung Kombinasi Minyak Atsiri sebagai Pengaroma Mayangsari, Fransisca Dita; Pratiwi, Elasari Dwi; Sari, Diah Indah Kumala; Aula Nurwanda, Friska Selsabillah
Majalah Farmasetika Vol 9, No 1 (2024)
Publisher : Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/mfarmasetika.v9i1.49912

Abstract

Masyarakat pada umumnya menggunakan produk krim deodoran-antiperspiran untuk menghilangkan bau badan. Namun, sebagian produk krim deodoran-antiperspiran dipasaran mengandung alumunium klorohidrat yang berpotensi menyebabkan kanker payudara bila digunakan terus menerus dalam jangka panjang. Pada penelitian ini dibuat formulasi sediaan natural krim deodoran-antiperspiran cream dengan bahan aktif tawas dan zinc ricinoleat. Namun, sediaan ini tidak memiliki aroma. Sedangkan aroma adalah salah satu aspek terpenting pada kosmetik. Salah satu cara yang dapat dilakukan untuk mengatasi hal ini adalah dengan menambahkan minyak atsiri. Tujuan dari penelitian ini adalah untuk membandingkan karakteristik fisik, stabilitas fisik serta tingkat kesukaan (hedonik) dari natural krim deodoran-antiperspiran cream yang mengandung kombinasi minyak atsiri (1% minyak jeruk manis dan 1% minyak nilam) (FB) dan tanpa kombinasi minyak atsiri (FA). Karakteristik dan stabilitas fisik yang diamati meliputi organoleptis, homogenitas, pH, daya sebar dan viskositas. Sedangkan pada uji tingkat kesukaan, yang diamati meliputi tekstur, warna, dan aroma. Hasil uji organoleptis dianalisis secara deskriptif. Hasil pH, daya sebar, viskositas dan hedonik dianalisis secara statistik menggunakan SPSS. Berdasarkan penelitian yang telah dilakukan, dapat disimpulkan bahwa penambahan kombinasi minyak atsiri (minyak nilam dan minyak jeruk manis) berpengaruh pada aspek aroma, warna dan pH dari natural krim deodoran-antiperspiran cream. Penambahan kombinasi minyak atsiri juga berpengaruh terhadap tingkat kesukaan. Panelis lebih menyukai aroma dari sediaan yang mengandung kombinasi minyak atsiri. Pada uji stabilitas fisik, diketahui bahwa penambahan kombinasi minyak atsiri mempengaruhi pH dan viskositas sediaan selama periode penyimpanan selama 90 hari pada suhu ruang (25°C ± 2°C).
Studi Formulasi dan Karakteristik Fisik Serum Spray Kombinasi Ceramide dan Tea Tree Oil serta Uji Aktivitas Antioksidan Menggunakan Metode DPPH Sasmitasari, Diana; Pratiwi, Elasari Dwi; Kumala Sari, Diah Indah
Majalah Farmasetika Vol 9, No 2 (2024)
Publisher : Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/mfarmasetika.v9i2.49479

Abstract

Paparan sinar matahari menyebabkan kulit menjadi kusam karena mengandung radiasi sinar UV yang dapat merusak lapisan kulit. Penggunaan kosmetik yang mengandung senyawa antioksidan seperti ceramide dan tea tree oil dapat melindungi kulit dari paparan sinar matahari. Ceramide dapat memperkuat skin barrier dan mencegah hilangnya kelembapan kulit yang berfungsi sebagai antiaging dan memberikan efek perbaikan pada kulit dengan menghambat sebagian efek yang tidak diinginkan terkait penuaan. Tea tree oil merupakan agen antioksidan yang berfungsi untuk menangkap radikal bebas, bahan penangkap radikal bebas meliputi α-terpinene, α-terpinolene dan γ-terpinene. Tujuan dari penelitian ini adalah untuk membandingkan karakteristik fisik dan  nilai aktivitas antioksidan serum spray yang mengandung kombinasi zat aktif ceramide dan tea tree oil. Metode penelitian secara eksperimental dengan membuat formula sediaan serum spray kombinasi ceramide dan tea tree oil dengan variasi konsentrasi 0,5%, 0,75%, dan 1% kemudian dilakukan pengujian karakteristik fisik dan aktivitas antioksidan. Hasil evaluasi karakteristik fisik berpengaruh terhadap parameter warna, aroma, pH, viskositas, dan daya sebar, tetapi tidak berpengaruh terhadap parameter konsistensi dan homogenitas sediaan. Hasil evaluasi nilai aktivitas antioksidan dari masing-masing formula didapatkan nilai IC50 terhadap kontrol (+) ceramide sebesar 33,9 ppm, kontrol (+) TTO 43,92 ppm, F1 sebesar 28,77 ppm, F2 sebesar 27,34 ppm, F3 sebesar 15,26 ppm yang termasuk dalam kategori sangat kuat. Kesimpulan dari penelitian ini yaitu dengan adanya peningkatan konsentrasi ceramide dan tea tree oil memberikan pengaruh terhadap karakteristik fisik sediaan dan nilai Inhibition Concentration (IC50).
Optimization of the Mixing of Hibiscus Flower (Hibiscus rose sinensis) Extract as a Lip Balm Color with Variations in Concentration Kumala Sari, Diah Indah; Mayangsari, Fransisca Dita; Pratiwi, Elasari Dwi
Journal of Fundamental and Applied Pharmaceutical Science Vol 4, No 1 (2023): August
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/jfaps.v4i1.16179

Abstract

Hibiscus rosa sinensis L. is widely used by the community to decorate the garden because of its splendor. In addition, Hibiscus flowers containing anthocyanin and flavonoids have antioxidants, which function as antioxidants against free radicals. This natural dye can be obtained by extracting Hibiscus flowers through maceration using 96% ethanol. In this research, Hibiscus flowers were obtained from Sendang Rejo Village, Lamongan Regency. In the extract process, the Hibiscus flower’s petals were blended until smooth, then added to 96% ethanol (1 liter) and stirred for 30 minutes. Filtrate results were taken, placed in a porcelain dish, and put in an oven at 60 °C for a day. Four formulas were made with varying levels of Hibiscus flower extract: F1 (0%), F2 (2%), F3 (4%), and F4 (6%). Physical evaluation included organoleptic, homogeneity, dispersibility, pH, and qualitative tests for the identification of anthocyanins. The results of the organoleptic, homogeneity, dispersion, pH, and identification of anthocyanins evaluations were then analyzed descriptively. The data from the organoleptic test indicated that F1 had an odorless white color, while F2, F3, and F4 had a red and white color with a distinctive Hibiscus flower aroma. The homogeneity test revealed that while F1 had good homogeneity, F2, F3, and F4 were not homogeneous (heterogeneous). The spreadability test on the four formulas did not fall within the range of requirements, namely 5-7 cm, with an average value of 3.53, but this was related to several significant reasons. In addition, the pH test results matched the requirements for topical preparations, namely 4.5–6.5, with an average value of 5.075. In conclusion, Hibiscus flower extract obtained through the maceration method with 96% ethanol could not give a homogeneous red color from the anthocyanin substance. Physical evaluation and anthocyanin identification tests also obtained good results.
Effectiveness of Citronella and Basil Essential Oil Spray as Repellents against Aedes aegypti Mosquitoes: Efektivitas Spray Minyak Atsiri Serai Wangi Dan Daun Kemangi Sebagai Repellent Nyamuk Aedes Aegypti Qomariyah, Laila Nurul; Kusumo, Djati Wulan; Pratiwi, Elasari Dwi
Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) Vol. 10 No. 1 (2024): (March 2024)
Publisher : Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/j24428744.2024.v10.i1.16499

Abstract

Background: In 2023, Dengue Fever cases in Indonesia reached 35,694 cases from January to May. Dengue Fever is caused by the bite of Aedes aegypti mosquitoes. Mosquito control efforts have been widely conducted, including the use of chemical insecticides. The use of chemical insecticides can lead to environmental contamination and cause skin irritation. An alternative approach that can be taken is to use natural insecticides. One of the natural insecticides that can be used as a repellent is citronella and basil essential oils. Citronella and basil essential oils contain geraniol and citronellal, which can cause mortality in mosquitoes. This study intends to evaluate the effectiveness of a spray mixture of basil leaves and citronella essential oil as a mosquito repellent. Materials and Methods: Aedes aegypti mosquitoes, basil leaf essential oil, citronella essential oil, propylene glycol, glycerin, butylated hydroxytoluena and etanol 96% v/v. Subsequently, an evaluation of physical properties was conducted, including organoleptic testing, pH, and viscosity evaluation, as well as irritation and repellent activity test. Results: The spray formulations in the control and F1 are clear in color, while F2 and F3 are clear with a slightly yellowish hue. The scent produced has the characteristic smell of citronella. The pH and viscosity tests resulted in pH values consistent with the skin's pH range of 4.5-7 and viscosity within the range of 1-1000 Cp. The spray formulation did not irritate after 48 hours of observation. The results of the effectiveness test indicate that F2 can protect against mosquito bites for 1 hour, while F3 can protect for 3 hours. Conclusion: Citronella essential oil and basil leaves are effective as a repellent for the Aedes aegypti mosquito for 3 hours of use in concentration 15%.
SNEDDS Sebagai Sistem Penghantaran Baru Berbasis Sediaan Gel Tea Tree Oil Untuk Anti Jerawat Firdani, Alnessia; Pratiwi, Mutia Dian; Pramitasari, Kharisma; Suryani, Putri Jian; Pratiwi, Elasari Dwi
Media Farmasi Vol 20 No 2 (2024): Media Farmasi Edisi Oktober 2024
Publisher : Jurusan Farmasi Poltekkes kemenkes Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32382/mf.v20i2.796

Abstract

Acne is a skin condition that is often discussed, especially among teenagers, because of its potential to damage self-confidence. The use of cosmetics that contain anti-acne active compounds from natural ingredients, such as tea tree oil, is one of the effective acne treatments. Tea tree oil is an essential oil that has hydrophobic and lipophilic properties. So, a good conveyor system such as SNEDDS is needed. The SNEDDS tea tree oil gel preparation in this study aims to assess the potential inhibition of the preparation against staphylococcus epidermidis, a type of acne-causing bacteria. The data analysis in this study uses descriptive methods, such as homogeneity test, organoleptic test, pH test, dispersion test, viscosity test, stability test, and antibacterial test. Antibacterial activity data is data obtained in the form of the diameter of the obstacle area and measured using a caliper. The results of the antibacterial activity test against staphylococcus epidermidis bacteria are as follows: positive control (Clindamycin) has an inhibition of 32.26 mm, F1 (SNEDDS tea tree oil 0% gel) does not inhibit, and F2 (SNEDDS tea tree oil 20% gel) has an inhibition of 24.44 mm. Thus, it can be concluded that SNEDDS tea tree oil gel has the ability to inhibit bacteria in the very strong category (>10mm).
EFFECT OF HAIR TONIC COMBINATION OF CINNAMOMUN ESSENSIAL OIL AND CANDLENUT ESSENSIAL OIL HAIR GROWTH IN VIVO Mutamimmah, Siti; Pratiwi, Elasari Dwi; Kusumo, Djati Wulan
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 9 No 4 (2024)
Publisher : Sekolah Tinggi Farmasi Muhammadiyah Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v9i4.1610

Abstract

Hair loss, often called alopecia, is characterized by excessive hair loss. One way to treat hair loss is to use hair tonic preparation. This study aimed to determine the effect of a combination of hair tonic cinnamon essential oil and candlenut essential oil on hair growth. The research method used included physical evaluation of the hair tonic preparation formulation by examining the physical quality, homogeneity, pH, viscosity, and stability of the hair tonic preparation. The effectiveness of hair growth was evaluated in vivo in rabbits. Its effectiveness measures hair growth and weight. Based on the results of the tests on the physical characteristics and physical stability of the hair tonic preparation, a combination of cinnamon essential oil and candlenut essential oil at concentrations of 0% (F0), 2.5% (F1), 5% (F2), and 7.5% (F3) was used. in organoleptic testing, the homogeneity, pH, and viscosity met the specified characteristics and stability requirements. The results of research testing the effectiveness of hair growth showed that the hair tonic combination of cinnamon essential oil and candlenut essential oil is effective for good hair growth in formula 3, with a hair length of 8 mm and a hair mass of 213.8 mg on day 21. Keywords: Candlenut essential oil, Cinnamon essential oil, Hair growth, Hair tonic, In vivo
Empowering PKK Mothers in Klagensrampat Village: Accelerating income through ASMAN TOGA management Fajri, Mega Barokatul; Bait, Jennifer Farihatul; Pratiwi, Elasari Dwi
Community Empowerment Vol 10 No 1 (2025)
Publisher : Universitas Muhammadiyah Magelang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31603/ce.12552

Abstract

The purpose of this community service is to empower PKK mothers in Klagensrampat Village, Maduran District, Lamongan Regency, through the "Income Acceleration Through ASMAN TOGA Management" program. This program aims to increase participants' knowledge regarding the classification and function of TOGA plants, as well as encourage product innovation using TOGA as raw materials. The stages of the activity include training and mentoring as well as monitoring and evaluation. This training is provided with materials on classifying types of toga and their properties, creating innovative products, packaging design materials and digital marketing. The results of this activity show an increase in participants' knowledge and skills, especially in creating new products that are innovative and have high selling value. This activity has succeeded in creating products that have the potential to be marketed internationally, including herbal medicine in the form of liquid drinks (temulawak and turmeric), herbal medicine powder (ginger and lemongrass), and gummy candy (temulawak and lime). In addition, participants also gain an understanding of how to design attractive packaging and logos, as well as effective digital marketing strategies. The target partners showed very active and enthusiastic participation during the mentoring process.
Evaluation of Skin Irritation Level and Effectiveness of Foot Sleeping Mask Containing Tengkawang Fat in Nanostructured Lipid Carriers System Fidayanti, Ayu; Mayangsari, Fransisca Dita; Pratiwi, Elasari Dwi
Jurnal FARMASIMED (JFM) Vol 7 No 2 (2025): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v7i2.2608

Abstract

One of the export commodities from the Non-Timber Forest Products (NTFP) group is tengkawang fruit. This fruit can be processed into fat which has properties similar to cocoa butter. The advantage of this fat compared to cocoa butter is that the price is relatively cheaper. However, the use of tengkawang fat in cosmetics is not widely known. Therefore, researchers are interested in developing cosmetic products based on tengkawang fat to treat xerosis of the feet. To increase occlusivity, tengkawang fat is formulated into an NLC (Nanostructured Lipid Carriers) system. In this research, a foot sleeping mask product was made containing NLC tengkawang fat with the addition of gel (to improve viscosity) and sweet orange oil (to improve aroma). The aim of this research was to determine the irritation skin level and effectiveness of moisturizing the skin of the soles of the feet from a foot sleeping mask containing NLC tengkawang fat. The results of the physical characteristics test show that the foot sleeping mask made meets the desired specifications. The results of skin irritation tests with 35 panelists showed that there was no redness or edema on the panelists' skin during 24, 48 and 72 hours of observation. The results of the moisture effectiveness test showed that the average moisture content of the soles of the panelists' feet on day 0 was 34.531%, while on day 28 (4 weeks) it was 42.815%. There was an increase in humidity of 8.284% during 4 weeks of use. The conclusion of this research is that a foot sleeping mask containing Tengkawang fat NLC can increase the moisture of the skin of the soles of the feet by 8.284% during 4 weeks of use.
Penambahan Probiotik Pada Formula Serum Antiaging terhadap Penentuan Sun Protection Factor (SPF) dan Aktivitas Antioksidan Pratiwi, Elasari Dwi; Mayangsari, Fransisca Dita; Sari, Diah Indah Kumala; Kusumo, Djati Wulan
Lumbung Farmasi: Jurnal Ilmu Kefarmasian Vol 6, No 2 (2025): Juli
Publisher : UNIVERSITAS MUHAMMADIYAH MATARAM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/lf.v6i2.30981

Abstract

Paparan sinar UV yang berlebihan mampu memperparah kondisi kulit wajah, sehingga perlu adanya pengembangan sediaan kosmetik yang mengandung antioksidan dan SPF. Probiotik diketahui mampu menyembuhkan eksim atopik, dermatitis atopik, menyembuhkan luka bakar, menghilangkan bekas luka, mengobati jerawat, dan mencegah penuaan dini, serta regenerasi kulit. Penelitian ini bertujuan mengetahui nilai antioksidan dan nilai SPF serum probiotik. Pada Penelitian akan dibuat 2 formula yaitu F1 (0%) dan F2 (1%), yang selanjutnya dilakukan pengukuran nilai antioksidan menggunakan metode DPPH dan nilai SPF menggunakan metode mansur. Pada pengukuran nilai SPF yaitu F1 dengan nilai SPF 5,632 dan F2 dengan nilai SPF 5,735, kedua formula masuk dalam kategori efektivitas SPF sedang. Sedangkan pada pengukuran nilai antikoksidan yaitu F2 dengan nilai IC50 10.20 ppm dan K+(Serum probiotik dan Vitamin C) dengan nilai IC50 9.47 ppm, kedua formula masuk dalam katgoeri aktivitas antioksidan sangat kuat. Dengan demikian, penambahan probiotik 1% memliki aktivitas antioksidan dan nilai SPF yang baik.
Inovasi Jaguser Sebagai Penguat Imunitas Di Masa Pasca Pandemic Covid 19 : Desa Banteng Putih Pratiwi, Elasari Dwi; Andininatus, Vivi Rifda; Rahmawati, Devi; al Mabruroh, Naily; Nanda, Diana Mei
JPEMAS: Jurnal Pengabdian Kepada Masyarakat Vol. 1 No. 1 (2022): JPEMAS : Jurnal Pengabdian Kepada Masyarakat
Publisher : Yayasan Pendidikan Tanggui Baimbaian

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.71456/adc.v1i1.20

Abstract

Menjaga daya tahan tubuh dimasa pasca pandemic COVID-19 sudah menjadi kebutuhan bagi manyarakat. Melalui program Kuliah Kerja Nyata Tematik dengan tema penguatan sumber daya lokal menuju desa inovatif dan profesional sebagai upaya pemulihan pasca COVID-19 diharapkan mampu memberdayakan masyarakat dengan keilmuan yang dimiliki. Salah satu program dari KKN Tematik COVID-19 adalah memberikan sosialisasi dan inovasi pembuatan serbuk minuman instan JAGUSER pada para pelaku UMKM. JAGUSER merupakan inovasi olahan yang berasalah dari bahan herbal jahe merah dan sereh wangi. Sosialisasi dan inovasi oembuatan dilakukan selama 1 hari dengan 2 tahap kegiatan, tahap pertama sosialisasi manfaat tanaman toga sebagai penguat imunitas dan tahap kedua yaitu melakukan demonstrasi pembuatan serbuk minuman instan JAGUSER. Setelah kegiatan ini, tim KKN Tematik Universitas Muhammadiyah Lamongan berharap agar imunitas masyarakat desa Banteng Putih lebih meningkat dan mampu menjadikan JAGUSER sebagai peluang usaha bagi pelaku UMKM, sehingga secara tidak langsung mampu meningkatkan kesejahteraan masyarakat Desa Banteng Putih Kecamatan Karanggeneng Kabupaten Lamongan di masa Pasca Pandemic COVID-19.
Co-Authors al Mabruroh, Naily Andininatus, Vivi Rifda Aula Nurwanda, Friska Selsabillah Bait, Jennifer Farihatul Devi Rahmawati, Devi Fajri, Mega Barokatul Fidayanti, Ayu Firdani, Alnessia Fransisca Dita Mayangsari Kumala Sari, Diah Indah Kusumo, Djati Wulan Mutamimmah, Siti Nanda, Diana Mei Pramitasari, Kharisma Pratiwi, Mutia Dian Qomariyah, Laila Nurul Sari, Diah Indah Kumala Sasmitasari, Diana Suryani, Putri Jian