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All Journal Pharmaciana: Jurnal Kefarmasian Journal of Biomedicine and Translational Research PROSIDING SEMINAR KIMIA Jurnal Kimia Mulawarman Indonesian Journal of Chemistry Jurnal Kesmas dan Gizi (JKG) JURNAL FARMASIMED (JFM) Jurnal Dunia Farmasi JURNAL ANALIS LABORATORIUM MEDIK Pelita Masyarakat Jurnal Indah Sains dan Klinis FORTE JOURNAL Jurnal Farmanesia Jurnal Multidisiplin Madani (MUDIMA) JURNAL KIMIA SAINTEK DAN PENDIDIKAN Jurnal ABDIMAS MUTIARA Jurnal Indah Sains dan Klinis
Ahmad Hafizullah Ritonga
Institut Kesehatan Medistra Lubuk Pakam, Deli Serdang, Indonesia
Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Materials Science & Nanotechnology Medicine & Pharmacology Nursing Physics Public Health Social Sciences Other

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Journal : Jurnal Farmanesia

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UJI AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL DAUN INSULIN (Smallanthussonchifolius) TERHADAP BAKTERI Bacillus cereus Kesaktian Manurung; Ahmad Ghazali; Ahmad Hafizullah; Ulfayani Mayasari
Jurnal Farmanesia Vol 4 No 1 (2017): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

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Abstract

Insulin leaves are known as one of the ingredients of traditional medicine. Insulin leaves contain potential substances such as tannins, alkaloids, flavonoids, saponins, and terpenoids which have antibacterial abilities. This study aims to determine the effectiveness of insulin leaf ethanol extract as an antibacterial. This research is an experimental study that includes the collection and processing of insulin leaf samples, examination of the characteristics of Simplisia, phytochemical screening, testing of the antibacterial diffusion method using a disk paper brace, and using the One Way ANOVA analysis method. The test results showed that the ethanol extract could inhibit bacterial growth at a concentration of 50 - 60% with an average resistor potential of 14.8 - 17.83 mm while Ampicillin as a comparison control averaged 33.62 mm. So that the ethanol extract of insulin leaves was effective in inhibiting the growth of Bacillus cereus bacteria with a minimum resistance concentration of 60 mg/ml. Keywords: Antibacterial, Bacillus cereus, insulin leaf extract
UJI AKTIVITAS ANTIDIABETES EKSTRAK ETANOL DAUN BANGUN-BANGUN (Plectranthus amboinicus Lour.) PADA TIKUS PUTIH JANTAN YANG DIINDUKSI ALOKSAN Zuhairiah Zuhairiah; Yosy Cinthya Eriwaty Silalahi; Ahmad Hafizullah; Ariyanti Ariska
Jurnal Farmanesia Vol 4 No 1 (2017): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

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Abstract

Bangun-Bangun leaves contain phytochemical compounds such as phenolic compounds and flavonoids which have potential as antioxidant activity. This study aims to determine the antidiabetic activity of the ethanolic extract of Bangun-Bangun leaves on reducing blood glucose levels (KGD) of male white rats by using the glucose tolerance test method and the alloxan induction test. The study was conducted by grouping rats where each group consisted of 5 rats, the fasting KGD was measured. Then, a group I was given Na-CMC 1% BW, group II was given glibenclamide 0.45 mg/kg BW, group III was given EEDBB at a dose of 200 mg/kg BW, group IV was given EEDBB at a dose of 250 mg/kg BW and group V was given EEDBB dose of 300 mg/kg BW. In the glucose tolerance test, each group was given a 50% concentration of glucose solution. Furthermore, measurements of KGD were carried out at 30, 60, 90, and 120 minutes. In alloxan induction, 25 test animals weighing ±150-200 g that had been fasted were divided into 5 groups and then KGD was measured. The rats were then induced with a dose of 150 mg/kg BW of alloxan intraperitoneally. Diabetic rats were then given the test preparation orally for 15 consecutive days. Furthermore, glucose levels were measured on the 3rd, 5th, 7th, 9th, 11th, 13th, and 15th days. The results concluded that EEDBB can reduce blood glucose levels of male white rats induced by alloxan.
Co-Authors Adiansyah Ahmad Ghazali Ardiansyah Ardiansyah Aritonang, Barita Ariyanti Ariska Arniat Christian Telaumbanu Barito Aritonang Barus, Ester Julianti Karolina Boy Isfa Boy isfa Debi Meilani Denny Akbar Tanjung Denny Akbar Tanjung Denny Akbar Tanjung Dicky Yuswardi Wiratma Eka Margareta Sinaga Eka Margareth Eliza Arman Gusliani Eka Putri Gusliani Eka Putri Hasni Yaturramadhan Harahap Hendri Faisal Herlina Herlina H Herlina Herlina Hermansyah Aziz Hestina Ida Ayu Putu Sri Widnyani Imel Santika Irmayani Irmayani Jenny Ria Sihombing Karnirius Harefa Kesaktian Manurung Khairiah, Khairiah Kusumastuti, Melati Yulia Lely Masnita Liver Iman Putra Zai Maniur Arianto Melinda Sela Nengsi Handayanti Gaho Nova Florentina Nova Florentina Ambarwati Novesar Jamarun Novita Br Ginting Rahmad Gurusinga Rahmi Novita Yusuf Rima Anggeraini Rizqa Hafizhah Harahap Salomo Sijabat Samran, Samran Shofian Syarifuddin Siahaan, Enzo W.B Siahaan, Maniur Arianto Sinaga, Arman Bemby Sri Wulan, Sri Suarnikan Hulu Sumardi . Suprianto Suprianto Syukri Arief Ulda Andriani Sijabat Ulfayani Mayasari Wiya Elsa Fitri Yosy Cinthya Eriwaty Silalahi Yulidar Laila Safitri Zuhairiah Nasution, Zuhairiah