Article Per Year (5 Year)
p-Index From 2021 - 2026
0.778
P-Index
This Author published in this journals
All Journal Journal of Tropical Life Science : International Journal of Theoretical, Experimental, and Applied Life Sciences Jurnal Produksi Tanaman Research Journal of Life Science MNJ (Malang Neurology Journal) Health Notions AcTion: Aceh Nutrition Journal Indonesian Journal of Clinical Pathology and Medical Laboratory (IJCPML) Jurnal EduHealth
Kalsumy, Umi
Department Farmakologi, Fakultas Kedokteran. Universitas Brawijaya, Malang, Indonesia.
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Dentistry Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Veterinary

Published : 9 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 1 Documents
Search

 1 
The Effect of Turmeric Decoctum to the Angiogenic Molecules Expression on Chicken Embryo Sultanah Zahariah; Sri Winarsih; Siti Candra Windu Baktiyani; Bambang Rahardjo; Umi Kalsum
Journal of Tropical Life Science Vol. 7 No. 1 (2017)
Publisher : Journal of Tropical Life Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/jtls.07.01.10

Abstract

Turmeric (Curcuma longa) is widely used as herbal medicine, not an exception by pregnant women. Turmeric consumption by expectant mothers requires standard dose, because of its antiangiogenic effect could be harmful on placentation process and embryonic development. This experiment was undertaken to determine the effect of different concentrations of turmeric decoctum to the expression of Vascular Endothelial Growth Factor Receptor-2 (VEGFR-2) and Angiopoietin 1 (Ang-1) on the 48-hours-old chicken embryo. In this study, turmeric was extracted using decoction method to mimic the common method as adopted by people. The turmeric decoctum were freeze dried into a powder form and was used in preparing the stock solution for 200 ppm (P1), 300 ppm (P2), and 400 ppm (P3) as experimental treatments. The control group (P0) received 2% DMSO without turmeric decoctum. These were administered on the yolk sack of 16 hours incubation of fertile chicken egg by number of 200 µL. After 48 hours incubation, the expression of VEGFR-2 and Ang-1 on the chicken embryo were counted by ImageJ software. The results revealed that there is no significant effect of turmeric decoctum to the expression of VEGFR-2 and Ang-1. This suggested that turmeric decoctum was safe up to 400 ppm on chicken embryo.
Co-Authors Adhinda Resta Camelia Agus Hendra Al Rahmad Anisak, Siti Bambang Rahardjo Darwitri, Darwitri Dominica Pita Sari Editya Fukata Een Nuraenah Elvira Sari Dewi Emanuel Hananto Evi Zahara Fitrah Aulia Lisabilla Hani Susianti Happy Kurnia Permatasari Hidayat Sujuti Husnul Khotimah Husnul Khotimah Karyono Mintaroem Kusworini Handono Kusworini Handono Laura Christiani Mohammad Muljohadi Ali Nihayati, Ellis Novida Ariani Nurdiana Nurdiana Nurfaizah Titisari Sulihah Nurlaili Ramli Nursari Abdul Syukur Pratama, Mirza Zaka Ra. Aminah Maya Rahmawati Wahyuni Siti Candra Windu Baktiyani Sri Andarini Sri Winarsih Sultanah Zahariah Sutrisno Sutrisno Tatit Nurseta Theakirana Firdaus Tri Yuliyani Wisnu Barlianto Wiyasa, I Wayan Arsana Yuni Sari