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All Journal Jurnal NERS Health Notions Jurnal Ilmu Kesehatan Journal of Midwifery and Nursing Jurnal Midpro JURNAL INOVASI DAN PENGABDIAN MASYARAKAT INDONESIA Jurnal Masyarakat Mengabdi Nusantara Journal for Quality in Public Health JGEN : Jurnal Pengabdian Kepada Masyarakat Jurnal Smart Keperawatan Journal Of Health Science Community Journal of Global Research in Public Health Journal of Community Engagement in Health Indonesian Journal of Nutritional Epidemiology and Reproductive Strada Jurnal Ilmiah Kesehatan (SJIK) Journal for Research in Public Health Journal for Quality in Women's Health
Riza Tsalatsatul Mufida
Universitas STRADA Indonesia
Religion Humanities Computer Science & IT Dentistry Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary Other

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Journal : Health Notions

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The Effect of Probiotics Lactobacillus Reuteri on Levels of Ifn-Γ (Th1) and Il-10 (Th2) Cytokines Cells in Mice Postpartum Induced by Staphylococcus Aureus Mufida, Riza Tsalatsatul
Health Notions Vol 1 No 2 (2017): April-June 2017
Publisher : Humanistic Network for Science and Technology (Address: Cemara street 25, Ds/Kec Sukorejo, Ponorogo, East Java, Indonesia 63453)

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Abstract

The direct causes of maternal mortality among others bleeding, preeclampsia, long delivery, abortion complications, and infections. Nosocomial infections are caused by Methicillin-Resistant Staphylococcus aureus (MRSA), obtained from infection Staphylococcus aureus and now resistant of antibiotics. The spread of bacterial resistance is existing drugs, pushing for extracting antibacterial source of other materials, such as the use of probiotics. Probiotics is as non-pathogenic microorganisms in food supplementation component, which has health benefits for the prevention and treatment of disease, when it is in sufficient quantities. Probiotics is as immunomodulatory and immunostimulatory, then activate all CD4+ T cells into Th1 (IFN-γ) and Th2 (IL-10) cells.Prove whether the effect of probiotic Lactobacillus reuteri to levels of IFN-γ and IL-10 cytokinecells on the spleen of mice model postpartum induced Stapgylococcus aureus bacteria.The study uses pure posttest-only randomized control-group experimental design which utilizes 40 mice (Balb/c) and gestasional aged 13 days which are divided into 8 sample groups. Dosis Lactobacillus reuteri 1x1010 CFU/mice in 250μl via a oral sonde (a gavaging needle). Dosis Staphyloccus aureus 5x107 CFU/mice in 200μl via spuit without needle per vaginal. The levels of IFN-γ and IL-10 cytokine were analyzed for enzyme linked immunosorbent assay (ELISA) kits. This study showed statistically that is significant in levels of IL-10 cells on the first day postpartum, levels of IL-10 and IFN-γ cytokineon the third day postpartum showed statistically that is no significant. There is influence of probiotic Lactobacillus reuteri on levels of IFN-Ɣ and IL-10 cytokine in mice postpartum induced Staphylococcus aureus. 
The Effect of Probiotics Lactobacillus Reuteri on Levels of Ifn-Γ (Th1) and Il-10 (Th2) Cytokines Cells in Mice Postpartum Induced by Staphylococcus Aureus Riza Tsalatsatul Mufida
Health Notions Vol 1, No 2 (2017): April-June
Publisher : Humanistic Network for Science and Technology (HNST)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (327.041 KB) | DOI: 10.33846/hn.v1i2.33

Abstract

The direct causes of maternal mortality among others bleeding, preeclampsia, long delivery, abortion complications, and infections. Nosocomial infections are caused by Methicillin-Resistant Staphylococcus aureus (MRSA), obtained from infection Staphylococcus aureus and now resistant of antibiotics. The spread of bacterial resistance is existing drugs, pushing for extracting antibacterial source of other materials, such as the use of probiotics. Probiotics is as non-pathogenic microorganisms in food supplementation component, which has health benefits for the prevention and treatment of disease, when it is in sufficient quantities. Probiotics is as immunomodulatory and immunostimulatory, then activate all CD4+ T cells into Th1 (IFN-γ) and Th2 (IL-10) cells.Prove whether the effect of probiotic Lactobacillus reuteri to levels of IFN-γ and IL-10 cytokinecells on the spleen of mice model postpartum induced Stapgylococcus aureus bacteria.The study uses pure posttest-only randomized control-group experimental design which utilizes 40 mice (Balb/c) and gestasional aged 13 days which are divided into 8 sample groups. Dosis Lactobacillus reuteri 1x1010 CFU/mice in 250μl via a oral sonde (a gavaging needle). Dosis Staphyloccus aureus 5x107 CFU/mice in 200μl via spuit without needle per vaginal. The levels of IFN-γ and IL-10 cytokine were analyzed for enzyme linked immunosorbent assay (ELISA) kits. This study showed statistically that is significant in levels of IL-10 cells on the first day postpartum, levels of IL-10 and IFN-γ cytokineon the third day postpartum showed statistically that is no significant. There is influence of probiotic Lactobacillus reuteri on levels of IFN-Ɣ and IL-10 cytokine in mice postpartum induced Staphylococcus aureus.Keyword: Lactobacillus reuteri, Staphylococcus aureus, IL-10, IFN-γ 
Co-Authors Asriyana Ilmiyanti Atik Fitrian Diyanti Basuki, stevani Bayu Prabowo Bayu Prabowo Candra Wahyuni Deonesia Pramita Deonesia Pramita Dewi Asrifatul Ulya Dina Oktavianty Elmida Siska Eri Puji Kumalasari Erma Retnaningtyas Euis Niawati Eutalia Anitu Eutalia Anitu Fachry Abda El Rahman Faiqotul Laila Faiqotul laila Fajriah, Asruria Sani Fajriyah , Nur Afidatul Febrita Dwi Ratnasari Fithria Muyassaroh Murti Fransiska Nona Frederika sondegau Frederika sondegau Fridya Oktavianti Soliviana Geystra Asmeranda Cahyaning Ciputri Heppy Indrawati Hudawati, Nurul Ika Novita Sari Indriani Agustin Intan Fazrin Joko Sutrisno Khusna, Cicin Amalia Kumalasari, Eri Puji Kumalasari, Eri Puji Kurnia Wira Susanti Lamtiar Manurung Lamtiar Manurung Lely Dian Agustina Lia Agustin Lidwina Kaka Matutina Maria De Fatima Moniz Maria De Fatima Moniz Maria Magdalena Hindom Maria Magdalena Hindom Maria Oktaviani Abu Maria Vita Insani Miftakhur Rohmah Miftakhur Rohmah Miftakhur Rohmah Miftakhur Rohmah Miftakhur Rohmah Miftakhur Rohmah, Miftakhur Mifthakhur Rohmah Mifthakhur Rohmah Mifthakur Rohmah Mila Karmila Mila Karmila Murti, Fithria Muyassaroh Nawangsari, Elliza Natania Niece Alce Ningsih, Dewi Andariya NINING ISTIGHOSAH Nining Istigosah Nita Dwi Astikasari Nona, Fransiska Novitasari , Ika Nurwijayanti Panca Radono Paulina Wungo Purba, Rince Putri Eka Sejati Putri, Ariesta Brinawaty Remita Ayu Agustin Remita Ayu Agustin Reni Yuli Astutik Reny Yuli Astutik Reny Yuli Astutik Respati, Laras Laxita Winda Retnaningtyas, Erma Retnaningtyas, Erma Retno Palupi Yonni Siwi Retno Palupi Yonni Siwi Retno Palupi Yonni Siwi Rince Purba Ripursari, Tety Risa Maya Sardewi Risna Lam Ali Risna Lam Ali Rohmah, Miftakhur Sejati, Putri Eka Shanty Natalia Sholichah, Nazilatul Maulinda Siti Julaichah Siti Julaichah Siti Julaichah Suci Hadia Yunda Sunariyah, Sunariyah Wati, Yana Widhiatuti, Dhanik Rita Wulandari, Anggrawati Yana Wati Yonni Siwi, Retno Palupi Yulida Ti'an Yulida Ti'an Zubaidah, Risna