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All Journal Jurnal Penelitian Pendidikan IPA (JPPIPA) Jurnal Health Sains Unram Journal of Community Service (UJCS) NUSANTARA: Jurnal Pengabdian Kepada Masyarakat Rumphius Pattimura Biological Journal Quantum Wellness : Jurnal Ilmu Kesehatan Innovation for Community Service Journal Kalwedo Sains (KASA) Jurnal Biosilampari: Jurnal Biologi
Abdul Mahid Ukratalo
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Nursing Physics Public Health Social Sciences Veterinary Other

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Methanol Extract Alstonia scholaris L. R. Br as Hepatoprotective Mice (Mus musculus) Infected with Plasmodium berghei ANKA Strains Martha Kaihena; Maria Nindatu; Abdul Mahid Ukratalo
Jurnal Penelitian Pendidikan IPA Vol 9 No 8 (2023): August
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v9i8.4834

Abstract

Alstonia scholaris L. R. Br is one of the traditional plants that contain natural antioxidant compounds which are thought to be able to repair damage to the liver cells of mice (Mus musculus) infected with Plasmodium berghei strain ANKA. This study aimed to determine the effect of methanol extract of Alstonia scholaris L. R. Br stem bark on levels of SGPT enzymes and liver cells of mice (Mus musculus) infected with Plasmodium berghei strain ANKA. Mice with a body weight of 20-30 g were infected with Plasmodium berghei as much as 0.1 ml per head and left until the percentage of parasitemia reached 1-5%. Then mice (Mus musculus) were given methanol extract of Alstonia scholaris L. R. Br stem bark at doses of 1, 10, 100, and 200 mg/kg BW for 4 consecutive days. After that, surgery was performed to take blood to observe SGPT enzyme levels and mice liver cells to be prepared with Hematoxylin Eosin (HE) staining. The results of ANOVA showed that the methanol extract of Alstonia scholaris L. R. Br stems bark doses of 1 mg/kg BW, 10 mg/kg BW, 100 mg/kg BW and 200 mg/kg BW could reduce SGPT enzyme levels and repair damage to the liver cells of mice infected with Plasmodium berghei ANKA strains
The Immunomodulatory Activity of Cinnamomum burmanni Bark Extract on Leucocyte Differentiation of Mice (Mus musculus) In Diabetes Mellitus Model Martha Kaihena; Abdul Mahid Ukratalo; Amos Killay; Nunun Ainun Putri Sari Banun Kaliky
Jurnal Penelitian Pendidikan IPA Vol 10 No 1 (2024): January
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v10i1.5947

Abstract

Diabetes mellitus frequently coexists with infection, leading to an immunological response characterised by an elevation in leukocyte levels. This research aimed to assess the immunomodulatory activity of an extract derived from the bark of Cinnamomum burmanni on the differentiation of leukocytes in a diabetes mellitus model using mice (Mus musculus). Prior to the administration of therapy, the glucose levels of all mice were assessed. Subsequently, groups K (+), P1, P2, and P3 were administered STZ at 0.2 ml per individual. The blood glucose levels (post-STZ blood glucose) were checked once more on the seventh day. In the event of a rise in blood glucose levels over (>200 mg/dL), subjects belonging to groups P1, P2, and P3 were administered Cinnamomum burmanii extract under the prescribed dosage. The intervention was administered for 14 days, and blood glucose levels were assessed on the final day of experimentation. On the final day of the experiment, blood samples were collected from the mice's tails in order to prepare blood preparations. The findings indicate that the methanol extract derived from cinnamon bark possesses immunomodulatory properties, as evidenced by its ability to decrease the population of eosinophils, lymphocytes, and monocytes while concurrently increasing the amount of neutrophils.
Potensi Porphyra Sp. Asal Desa Allang, Pulau Ambon sebagai Sumber Pangan Fungsional Berbasis Makronutrien Lokal untuk Mendukung Kesehatan Masyarakat Abdul Mahid Ukratalo; Martha Kaihena
Quantum Wellness : Jurnal Ilmu Kesehatan Vol. 3 No. 2 (2026): Juni: Quantum Wellness : Jurnal Ilmu Kesehatan
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62383/quwell.v3i2.3306

Abstract

Porphyra sp. seaweed is a marine biological resource with significant potential as a functional food ingredient, particularly in the coastal regions of Indonesia. This study aims to analyze the macronutrient content of Porphyra sp. from Desa Allang, Ambon Island, and to evaluate its potential as a functional food source based on local nutritional resources. Protein, carbohydrate, fat, moisture, and ash contents were analyzed using the AOAC method. The results indicate that Porphyra sp. contains 13.77% protein, 15.78% carbohydrates, and 1.35% fat, reflecting a high nutritional value with low fat content, thus meeting the characteristics of functional foods that provide health benefits to the community. The moisture content obtained was 11.55%, which is relatively low and is suspected to be influenced by the drying method using an oven. Furthermore, the ash content of 21.66% indicates a relatively high mineral content, contributing additional nutritional value that supports biological functions and overall health. The macronutrient composition is influenced by environmental factors such as habitat, water depth, water quality, and the growth phase of the seaweed. With its comprehensive nutritional profile, Porphyra sp. holds promise as a raw material for functional food development that not only fulfills nutritional requirements but also supports the enhancement of public health.
Co-Authors Amos Killay Ayal, Yonri Brian Saputra Manurung CECILIA ANNA SEUMAHU CECILIA ANNA SEUMAHU Cut Charolina Pattiwaellapia Dece Elizabeth Sahertian Deford Christy Birahy Deirdre Livia Petta Fuadiska Salamena Handy Erwin Pier Leimena Jehuda Daniel Nussy Kaliky, Arief Rahman Shabri Kaliky, Nunun Ainun Putri Sari Banun Maria Nindatu Maria Nindatu Martha Kaihena Martha Kaihena Martha Kaihena Martha Kaihena Martha Kaihena Martha Kaihena Monalisa Pertiwi Jeriska Taihuttu Moniharapon, Debby D Nindatu, Maria Riskia Tirta Nirwana Sopacua Rocky Genestho Kubela Ronald Darlly Hukubun Sahertian, Dece Elisabeth Sahertian, Dece Elizabeth Tarangi, Filep Marfil Umagapi, Muhammad Cesar Vanessa Yosiana Matital Windy Natalia Nusaly Wisnanda, Bayu