Article Per Year (5 Year)
p-Index From 2021 - 2026
1.665
P-Index
This Author published in this journals
All Journal International Journal of Public Health Science (IJPHS) Pharmaciana: Jurnal Kefarmasian MPI (Media Pharmaceutica Indonesiana) Eksakta : Berkala Ilmiah Bidang MIPA Jurnal Mandala Pharmacon Indonesia JURNAL ILMIAH OBSGIN : Jurnal Ilmiah Ilmu Kebidanan & Kandungan BERNAS: Jurnal Pengabdian Kepada Masyarakat Jurnal Pengabdian kepada Masyarakat Health Media Jurnal Kesehatan dr. Soebandi
Wima Anggitasari
Pharmacy Study Program, Faculty Of Health Sciences, Universitas Dr. Soebandi
Religion Agriculture, Biological Sciences & Forestry Humanities Astronomy Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Dentistry Economics, Econometrics & Finance Education Energy Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Mathematics Mechanical Engineering Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary Other

Published : 13 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 13 Documents
Search

 1   2 
UJI EFEK ANALGESIK INFUSA DAUN CENGKEH (Syzygium Aromaticum (L.) Merr. & L. M. Perry) PADA MENCIT YANG DIINDUKSI ASAM ASETAT Anggitasari, Wima
JURNAL ILMIAH OBSGIN : Jurnal Ilmiah Ilmu Kebidanan & Kandungan P-ISSN : 1979-3340 e-ISSN : 2685-7987 Vol 14 No 2 (2022): JUNI
Publisher : NHM PRESS

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36089/job.v14i1.759

Abstract

Pain is one of the things that people often complain about, which causes patients to come to health facilities. Many studies related to the development of drugs from herbal plants have been carried out considering the efficiency of herbal plants and concerns about the side effects of chemical drugs. One of the plants that has the potential to be developed as an analgesic is Clove. This study is an experimental study with mice where the test animals were divided into 5 groups, namely group I (negative control), group II (positive control), group III (clove leaf infusion at a dose of 200 mg/kgBW), group IV (clove leaf infusion). dose of 400 mg/kgBW) and group V (clove leaf infusion at a dose of 800 mg/kgBW). This study uses the Writing reflex test method. From the results of data analysis, it is known that groups II, III, IV and V have significant differences with group I (negative control). The calculation of the percentage of protection showed that the infusion treatment group at doses of 200 mg/kgBW, 400 mg/kgBW and 800 mg/kgBW had a percentage of protection 50%. The conclusion of this study is that clove leaf infusion has the potential to be developed as an analgesic drug.
Ketepatan Penggunaan Obat Oral Antidiabetik pada Pasien Diabetes Melitus Tipe 2 di Instalasi Rawat Inap Pebriarti, Iski Weni; Anggitasari, Wima; Mayasari, Shinta; Darrojah, Urfi Narva’u; Pramesti, Lita Aulia
MPI (Media Pharmaceutica Indonesiana) Vol. 6 No. 1 (2024): JUNE
Publisher : Fakultas Farmasi, Universitas Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24123/mpi.v6i1.6386

Abstract

Diabetes Melitus (DM) merupakan salah satu penyakit bersifat tidak menular yang masih menjadi permasalahan kesehatan secara global. Berbagai penelitian epidemiologi menunjukkan bahwa angka kejadian DM tipe 2 cenderung pada tren yang mengalami peningkatan di berbagai penjuru dunia. Indonesia adalah salah satu negara yang juga diperkirakan mengalami kenaikan jumlah pasien DM. Ketepatan pengobatan memiliki peranan yang sangat penting untuk mencegah ataupun menunda komplikasi makrovaskluar dan mikrovaskular, meningkatkan kualitas hidup dan juga harapan hidup. Penelitian ini bertujuan untuk mengevaluasi ketepatan penggunaan antidiabetik secara oral pada pasien DM tipe 2 di instalasi rawat inap salah satu rumah sakit yang terletak di Kabupaten Jember. Evaluasi ketepatan pengobatan dilakukan berdasarkan aspek tepat indikasi, tepat obat, tepat pasien dan dosis. Ketepatan pengobatan atau pengobatan rasional berdasarkan tepat indikasi, tepat obat, tepat pasien, dan tepat dosis masing-masing secara berurutan adalah 100%; 95,45%; 77,27%; dan 77,27%. Kesimpulan hasil akhir evaluasi menunjukkan bahwa ketepatan pengobatan adalah sebesar 59,09% dan ketidaktepatan pengobatan sebesar 40,91%. Diabetes Mellitus (DM) is a global health problem. Various epidemiological studies show that the incidence of type 2 DM is increasing in various parts of the world. Indonesia is one of the countries that isexpected to experience an increase in the number of people with DM. Appropriate treatment has an important role to prevent or delay macrovascular and microvascular complications, improve quality of life and also life expectancy. This study aimed to evaluate the appropriateness of using oral antidiabetics in type 2 DM patients in a hospital at Jember Regency. Assessment of the treatment appropriateness was carried out based on the aspects of the right indication, right drug, right patient, and right dose. Appropriate or rational treatment based on the right indication, right drug, right patient, and right dose respectively was 100%; 95.45%; 77.27%; and 77.27%. The final results of the evaluation showed that the rationality of treatment was 59.09% and the irrationality of the treatment was 40.91%.
Immunomodulator Effect of Cnidoscolus aconitifolius Leaves Extract on CD4+ and CD8+ Expression in Salmonella typhimurium infected mice Hidayati, Sholihatil; Susanti, Dhina Ayu; Destiawan, Rian Anggia; Muflihah, Ahdiah Imroatul; Handayani, Rizka; Anggitasari, Wima
Pharmaciana Vol. 14 No. 1 (2024): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/pharmaciana.v14i1.27050

Abstract

Typhoid fever is a common health problem in the community caused by Salmonella bacteria. The incidence rate of this infection will increase if a person's immune system is weakened. Plant extracts are generally considered to be potential immunomodulatory agents developed, which have smaller side effects. Research shows that Cnidoscolus aconitifolius leaves have medicinal properties including as hepatoprotective, antidiabetic, and anticardiovascular. The results of the antioxidant activity test show the results that Cnidoscolus aconitifolius leaves extract (CAE) has potential as an antioxidant with a very strong category. This study was conducted to determine the effect of giving Japanese papaya leaf extract on CD4+ and CD8+ expression in Babl/c mice induced by Salmonella typhimurium bacteria. The study was started by preparing 70% ethanol extract from Cnidoscolus aconitifolius leaves and preparing 30 Babl/C mice as experimental animals which were divided into 6 groups (healthy control, negative control, positive control and treatment group by giving CAE dose of 100 mg/kgbw, 200 mg/kgbw and 400 mg/kgbw). Induction was carried out by oral infection with Salmonella thypimurium bacteria. After 3 days the infected mice were treated orally once a day for 7 days. Evaluation of CD4+ and CD8+ expression was carried out using the flowcytometer method of the lymph organs. Data analysis was carried out by the Anova test followed by the post hoc test (Tukey) using the SPSS for Windows application. The results showed that giving CAE at doses of 100 mg/kgbw, 200 mg/kgbw and 400 mg/kgbw could increase the expression ratio of CD4+ and CD8+, whereas giving CAE at a dose of 400 mg/kgbw showed significantly different results (p<0.05) to the negative control. This shows that the CAE has potential as an immunomodulatory agent that can improve immune function.
Co-Authors AHDIAH IMROATUL MUFLIHAH Akrom, Akrom Aliyah Purwanti Aninda Fellysia Wibowo Bella Kharisma Rindiantika Darrojah, Urfi Narva’u Dhina Ayu Susanti Dyan Wigati Falakh Noferyana Hartania Wati Hidayati, Sholihatil Iski Weni Pebriarti Iski Weni Pebriarti lindawati setyaningrum Mohammad Rofik Usman Pebriarti, Iski Weni Pramesti, Lita Aulia RIAN ANGGIA DESTIAWAN Rizka Handayani Rizka Handayani Shinta Mayasari Sholihatil Hidayati Susanti, Dhina Ayu