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All Journal Pharmaciana: Jurnal Kefarmasian Farmasains : Jurnal Ilmiah Ilmu Kefarmasian Jurnal Kreativitas PKM Jurnal Ilmiah Ecosystem Pharma Xplore : Jurnal Sains dan Ilmu Farmasi HERBAPHARMA : Journal of Herb Farmacological Journal of Holistic and Health Sciences (Jurnal Ilmu Holistik dan Kesehatan) Jurnal Buana Farma JIFI (Jurnal Ilmiah Farmasi Imelda) Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Jurnal Pijar MIPA Journal of Pharmaceutical and Sciences. Organisms: Journal of Biosciences Parapemikir Jurnal Ilmiah Farmasi Journal of Pharmaceutical Science and Clinical Pharmacy (PSCP) Jurnal Medika Farmaka Kartika : Jurnal Ilmiah Farmasi
Syumillah Saepudin
Program Studi Farmasi, Fakultas MIPA Universitas Al Ghifari, Bandung, Jawa Barat Indonesia
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Nursing Physics Public Health Social Sciences Veterinary

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An AKTIVITAS ANTIOKSIDAN DAN FOTOPROTEKSI DARI EKSTRAK SERTA FRAKSI DAUN JARUM TUJUH BILAH (Pereskia bleo (Kunth)D.C) Irma Erika Herawati; Ginayanti Hadisoebroto; Ita Inayah; Lisna Dewi; Syulastri Effendi; Syumillah Saepudin
Pharma Xplore : Jurnal Sains dan Ilmu Farmasi Vol 10 No 2 (2025): Pharma Xplore : Jurnal Sains dan Ilmu Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/22pa7716

Abstract

Pereskia bleo (Kunth) D.C, commonly known as “jarum tujuh bilah,” is a plant widely found in Indonesia with elliptic to oblong-shaped leaves. This plant is traditionally recognized for its therapeutic properties, including treatments for rheumatism, inflammation, gastric disorders, ulcers, diabetes, hypertension, and as a body revitalizer. The leaves of this plant are known to contain various secondary metabolites, such as alkaloids, tannins, saponins, flavonoids, steroids, and phenolic compounds. These constituents exhibit antioxidant activity and the ability to absorb ultraviolet radiation, indicating potential as a natural sunscreen agent. This study aims to evaluate the antioxidant and photoprotective activities of the extract and fractions of P. bleo leaves through in vitro assays using UV-Vis spectrophotometry. Extraction was conducted via maceration using 70% ethanol as the solvent, followed by liquid–liquid fractionation with solvents of varying polarities: distilled water, n-hexane, and ethyl acetate. The results demonstrated that the ethanolic extract exhibited strong antioxidant activity with an IC₅₀ value of 41.5 ppm and an antioxidant activity index (AAI) of 0.963. The highest photoprotective activity was observed in the ethyl acetate fraction, with an SPF value of 73.229 (categorized as ultra protection) and an erythema transmission percentage of 0.034797 (indicative of effective sunblock activity)
Co-Authors Ade Cahyati Ajeng, Nurtina Dwi Al-Azzahra, Yunita Alifia Salsabila Annisa Khoerunnisa Baiq Vera El Viera Dadan Rohdiana Destiati, Yinyin Dewi, Anisya Dewi, Lisna Diani, Riski Dini Febrianty El Viera, Baiq Vera Ginayanti Hadisoebroto Henny Setiawati Herawati, Sinta Oktaviani Herliyani, Widya Hidayat, Taufik Septiyan inayah, ita Indria, Nefha Irma Erika Herawati Irma Erika Herawati Ita Inayah Kartikawati, Endah Kusdi Hartono Kusdi Hartono, Kusdi Lisna Dewi Luthfiyah Irbah As Saidah Marni, Aulia Mudrikah Ramdhani, Humairo Nurul Rahmayanti Nuur Hanifah, Hesty Octaviani, Anindita Rahayu, Iseu Raihani Febriani Sari, Dea Permata Septiyan, Taufik Syulastri Effendi Wasih, Efriliya Andila Widiyaningrum, Eva Mutba Widiyawati, Ida Erna Wulansari Wulansari Yasmiwar Susilawati Yunita Al-Azzahra Yus Hargono Cahyaning Yudi