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PRO-INFLAMASI VERSUS ANTI-INFLAMASI SITOKIN: MITOS ATAU KENYATAAN Pasaribu, Sumihar M. R.
Majalah Ilmiah METHODA Vol. 14 No. 1 (2024): Majalah Ilmiah METHODA
Publisher : Universitas Methodist Indonesia

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Abstract

Inflammation is characterized by interactions between pro- and anti-inflammatory cytokines. Cytokines are generally classified in one or another category: interleukin-1 (IL-1), tumor necrosis factor (TNF), gamma-interferon (IFN-γ), IL-12, IL-18 and granulocyte-macrophage colony-stimulating factor, . classified as pro-inflammatory cytokines while IL-4, IL-10, IL-13, IFN-α and transforming growth factor-β are anti-inflammatory cytokines. In this review, it is demonstrated that this classification is too simplistic and provides many examples illustrating that certain cytokines can behave as both pro- and anti-inflammatory cytokines. It is true, the amount of cytokines, the nature of the target cells, the nature of the activation signal, the nature of the cytokines produced, the timing, the order of action of the cytokines and even the experimental model are parameters that greatly influence the properties of the cytokines.
PENYULUHAN PEMBERDAYAAN MASYARAKAT DALAM PENCEGAHAN STUNTING DESA AJIJULU, KABUPATEN KARO Siahaan, Jekson Martiar; Silitonga, Hendrika Adriana; Lim, Hadyanto; Pasaribu, Sumihar M. R.; Tarigan, Menang Bastanta; Jamnasi, Juli; Sinatra, Jadeny; Simanjuntak, Salomo Garda Utama; Sembiring, Budi Darmanta; Pakpahan, Edwin Anto; Hutagalung, Sanggam B.; Sinurat, Suryati; Br. T. Tambun, Gita Sradha; Hakim, Enggrek Pelita
Jurnal Pengabdian Pada Masyarakat METHABDI Vol 3 No 1 (2023): Jurnal Pengabdian Pada Masyarakat METHABDI
Publisher : Universitas Methodist Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46880/methabdi.Vol3No1.pp11-14

Abstract

Community Service (PKM) conducted by the Faculty of Medicine at the Indonesian Methodist University provides counseling on stunting prevention. PKM was held on April 14-16 2023 in Ajijulu Village, Tigapanah District, Karo Regency, North Sumatra. Lectures, discussions and motivations are used as orientation methods. Question and answer discussions were held with the aim of gaining insight, understanding and solutions to solve the problems and limitations faced by the local community. The results of the PKM suggestions and research are very effective, considering that there are still many people who are ignorant of stunting prevention. This counseling increases public awareness about stunting prevention. Residents of Ajijulu must be aware and know the importance of preventing stunting, starting from the time of pregnancy and the first 1000 days of life for toddlers.
HUBUNGAN JENIS KELAMIN, MASA KERJA, DAN POSISI KERJA DENGAN GANGGUAN OTOT RANGKA AKIBAT KERJA PADA PETANI DI KABUPATEN DELI SERDANG TAHUN 2022: THE RELATIONSHIP OF GENDER, LENGTH OF WORK, AND WORK POSITION WITH WORK-DUE TO SKELETAL MUSCLE DISORDERS IN FARMERS IN DELI SERDANG DISTRICT YEAR 2022 Pasaribu, Sumihar; Tanjung, Lina Febriani; Girsang, Rostiodertina; Alwi, Fahrizal
Jurnal Kedokteran Ibnu Nafis Vol. 14 No. 1 (2025): Juni 2025
Publisher : Fakultas Kedokteran Universitas Islam Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30743/jkin.v14i1.822

Abstract

Gangguan otot rangka merupakan salah satu masalah kesehatan yang sering dialami pekerja di sektor pertanian akibat postur kerja yang tidak ergonomis, masa kerja panjang, dan beban kerja fisik yang berat. Penelitian ini bertujuan untuk menganalisis hubungan antara jenis kelamin, masa kerja, dan posisi kerja terhadap gangguan muskuloskeletal pada petani di Kabupaten Deli Serdang. Penelitian menggunakan desain cross-sectional dengan 30 responden yang dipilih melalui metode consecutive sampling. Data dikumpulkan menggunakan kuesioner, penilaian Rapid Entire Body Assessment (REBA) untuk posisi kerja, dan Nordic Body Map (NBM) untuk keluhan gangguan otot rangka. Analisis bivariat menunjukkan hubungan signifikan antara jenis kelamin (p = 0,045; PR = 0,167), masa kerja (p = 0,007; PR = 13,500), dan posisi kerja (p = 0,001; PR = 22,667) terhadap gangguan otot rangka. Posisi kerja yang tidak ergonomis merupakan faktor risiko utama. Temuan ini menegaskan pentingnya intervensi ergonomis, edukasi, dan pelatihan untuk mengurangi prevalensi gangguan muskuloskeletal pada petani.
PRO-INFLAMASI VERSUS ANTI-INFLAMASI SITOKIN: MITOS ATAU KENYATAAN Pasaribu, Sumihar M. R.
Majalah Ilmiah METHODA Vol. 14 No. 1 (2024): Majalah Ilmiah METHODA
Publisher : Universitas Methodist Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46880/methoda.Vol14No1.pp120-131

Abstract

Inflammation is characterized by interactions between pro- and anti-inflammatory cytokines. Cytokines are generally classified in one or another category: interleukin-1 (IL-1), tumor necrosis factor (TNF), gamma-interferon (IFN-γ), IL-12, IL-18 and granulocyte-macrophage colony-stimulating factor, . classified as pro-inflammatory cytokines while IL-4, IL-10, IL-13, IFN-α and transforming growth factor-β are anti-inflammatory cytokines. In this review, it is demonstrated that this classification is too simplistic and provides many examples illustrating that certain cytokines can behave as both pro- and anti-inflammatory cytokines. It is true, the amount of cytokines, the nature of the target cells, the nature of the activation signal, the nature of the cytokines produced, the timing, the order of action of the cytokines and even the experimental model are parameters that greatly influence the properties of the cytokines.
Pengaruh Kombinasi Mindfulnes Breathing And Guided Imagery Terhadap Penurunan Kecemasan Emosi Negatif Pada Ibu Post Sectio Caesarea Purba, Tetty Junita; Ariani, Peny; Pasaribu, Sumihar; Sitorus, Friska Ernita; Sembiring, Alprindo
BEST Journal (Biology Education, Sains and Technology) Vol 8, No 2 (2025): September 2025
Publisher : Program Studi Pendidikan Biologi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30743/best.v8i2.12206

Abstract

Abstrak- Sectio caesarea merupakan prosedur bedah mayor yang sering menimbulkan dampak psikologis berupa kecemasan dan emosi negatif pada ibu postpartum. Kondisi ini dapat mengganggu pemulihan, menghambat ikatan ibu dan bayi, serta meningkatkan risiko depresi postpartum. Intervensi non-farmakologis seperti mindfulness breathing dan guided imagery dipandang efektif dalam menurunkan kecemasan dan meningkatkan regulasi emosi, namun penelitian mengenai kombinasi keduanya masih terbatas. Penelitian ini bertujuan untuk menganalisis pengaruh kombinasi mindfulness breathing dan guided imagery terhadap penurunan kecemasan dan emosi negatif pada ibu post-sectio caesarea. Penelitian menggunakan desain pre–post test without control group dengan jumlah responden sebanyak 49 orang ibu post-sectio caesarea yang dipilih melalui teknik purposive sampling. Instrumen penelitian meliputi kuesioner Hospital Anxiety and Depression Scale-Anxiety (HADS-A) untuk mengukur kecemasan dan Positive and Negative Affect Schedule-Negative Affect (PANAS-NA) untuk mengukur emosi negatif. Data dianalisis menggunakan uji normalitas Shapiro-Wilk dan uji paired t-test.Rata-rata skor kecemasan menurun dari 11,18 (SD = 3,68) menjadi 6,90 (SD = 4,34), sedangkan rata-rata skor emosi negatif menurun dari 29,96 (SD = 5,55) menjadi 23,73 (SD = 5,88). Uji paired t-test menunjukkan adanya perbedaan signifikan pada kecemasan (t(48) = 7,95; p < 0,001) dan emosi negatif (t(48) = 8,42; p < 0,001). Kombinasi mindfulness breathing dan guided imagery terbukti efektif menurunkan kecemasan dan emosi negatif pada ibu post-sectio caesarea. Intervensi ini sederhana, mudah diterapkan, minim efek samping, dan dapat diintegrasikan ke dalam praktik keperawatan maternitas sebagai upaya mendukung pemulihan psikologis ibu postpartum
PENYULUHAN PEMBERDAYAAN MASYARAKAT DALAM PENCEGAHAN STUNTING DESA AJIJULU, KABUPATEN KARO Siahaan, Jekson Martiar; Silitonga, Hendrika Adriana; Lim, Hadyanto; Pasaribu, Sumihar M. R.; Tarigan, Menang Bastanta; Jamnasi, Juli; Sinatra, Jadeny; Simanjuntak, Salomo Garda Utama; Sembiring, Budi Darmanta; Pakpahan, Edwin Anto; Hutagalung, Sanggam B.; Sinurat, Suryati; Br. T. Tambun, Gita Sradha; Hakim, Enggrek Pelita
Jurnal Pengabdian Pada Masyarakat METHABDI Vol 3 No 1 (2023): Jurnal Pengabdian Pada Masyarakat METHABDI
Publisher : Universitas Methodist Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46880/methabdi.Vol3No1.pp11-14

Abstract

Community Service (PKM) conducted by the Faculty of Medicine at the Indonesian Methodist University provides counseling on stunting prevention. PKM was held on April 14-16 2023 in Ajijulu Village, Tigapanah District, Karo Regency, North Sumatra. Lectures, discussions and motivations are used as orientation methods. Question and answer discussions were held with the aim of gaining insight, understanding and solutions to solve the problems and limitations faced by the local community. The results of the PKM suggestions and research are very effective, considering that there are still many people who are ignorant of stunting prevention. This counseling increases public awareness about stunting prevention. Residents of Ajijulu must be aware and know the importance of preventing stunting, starting from the time of pregnancy and the first 1000 days of life for toddlers.
Hubungan Indeks Massa Tubuh dengan Kadar Gula Darah Post Prandial Br. Siahaan, Thresia Deswinta; Pasaribu, Sumihar; Sitompul, Donald F
Jurnal Kedokteran Methodist Vol. 13 No. 1 (2020): Jurnal Kedokteran Methodist
Publisher : Universitas Methodist Indonesia

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Abstract

Background : Obesity is a disorder or disease characterized by excessive accumulation of fatty tissue in the body. Obesity occurs because of an imbalance between incoming and outgoing energy. Obesity / overweight has become a global pandemic worldwide and is declared by the World Health Organization as the biggest chronic health problem. Blood glucose levels in normal conditions tend to increase slightly, but after reaching the age of 50 years, the increase is progressive, especially for people who do not do physical Activity Normal blood glucose levels are between 70-110 mg/dl after fasting for 8 hour and 2 hour after eating, the blood glucose level should be below 200 mg/dl. Blood glucose levels increase after eating because there is a supply of glucose from the food consumed. Purpose Of The Study : To determine the relationship between body mass index and postprandial blood sugar levels. Research Methods : This types of research is research using the literature method. Result : From several research articles that explain that there is a relationship between body mass index and postprandial blood sugar levels.  
FAKTOR-FAKTOR YANG MEMPENGARUHI KEJADIAN DIARE PADA BALITA DI PUSKESMAS SELURUH INDONESIA Marpaung, Angelina Patricia Br; Pasaribu, Sumihar; Sinatra, Jadeny
Jurnal Kedokteran Methodist Vol. 12 No. 1 (2019): Jurnal Kedokteran Methodist
Publisher : Universitas Methodist Indonesia

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Abstract

Background :Diarrhea is a bowel movement with a flabby stool consistency usually accompanied by an increase in frequency and if the stool weight is measured more than 200g per day. Diarrhea is declared acute, if it lasts less than 14 days. And declared persistent if it occurs between 14-28 days. Chronic diarrhea, if diarrhea occurs more than 4 weeks. In 2013 in Indonesian, diarrhea was one of the number two killers of children under five after ISPA( Acute Respiratory Infection) and around 10,000 per child died from diarrhea. The prevalence of diarrhea in basic health research 2013, diarrhea is spread across all age groups with the highest prevalence detected in children under five (1-4 years) namely 16,7%. This study aims to determine the factors that influence the incidence of diarrhea in children under five in public helath centers throughout indonesian. Method: This type of research uses the method of literature study or literature review with a maximum time span of journal publishing of 5 years from 2015 to 2020. The population in this study is mothers who have toddlers with diarrhea. Results: The results of this study indicate that the factors that influence the incidence of diarrhea in children under five in public healt centers throught indonesian based on the research variabels are nutrional status, immunization, exclusive breastfeeding, personal hygiene and environmental sanitation. It can be concluded that the most dominant factors affecting the incidence of diarrhea in infants are exclusive breastfeeding. The average previous study used a cross sectional study design with bivariate analysis statistical tests through the chi square test with different number of respondents and research locations. Suggestion: For the government, it is expected to increase counseling activities regarding diarrheal disease with the help of doctors or health center cadres, about the importance of clean and healthy living behavior.