Garuda - Garba Rujukan Digital

Potensi Ekstrak Choromolaena odorata dan Mikaina micrantha Sebagai Antikanker Ryadi, Yusuf; Saifanah Setiawan, Nabilah; Batubara, Irmanida; Mariya, Silmi
JURNAL MEDIA KESEHATAN Vol. 17 No. 2 (2024): Jurnal Media Kesehatan Poltekkes Kemenkes Bengkulu Volume 17 No 2 Desember 202
Publisher : Politeknik Kesehatan Kemenkes Bengkulu

Show Abstract | Download Original | Original Source | Check in Google Scholar

The Asteraceae family has beneficial medicinal effect as anticancer, such as Chromolaena odorata and Mikaina micrantha. This study we investigated the potency of two Asteraceace plants and determined their active compounds. The plants were extracted using distilled water and then fractionated with chloroform. The phytochemical content, and anticancer potency was determined by literature study. The results showed that both plants contained essential oils, flavonoids, phenolics, terpenoids, and steroids. Toxicity to shrimp larvae through the Brine Shrimp Lethality Test (BLST) showed that both plants were toxic , so they were thought to be anticancer. Ombuin and vanylic acid compounds in C. odorata are reported its bioactive compound has activity anticancer. M. micrantha has less potential as an anticancer and more activity as an anti-inflammatory.

Exploration of Wedelia trilobata, Acmella paniculata, Ageratum conyzoides, and Crassocephalum crepidiodes as Antibacterial Plants Ryadi, Yusuf; Alzamori, Winda; Batubara, Irmanida; Suparto, Irma Herawati
Jurnal Jamu Indonesia Vol. 8 No. 3 (2023): Jurnal Jamu Indonesia
Publisher : Tropical Biopharmaca Research Center, IPB University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/jji.v8i3.347

Some Asteraceae plants are reported to contain phytochemicals and to show high antibacterial activity. This study aims to determine the highest antibacterial activity of Wedelia trilobata, Acmella paniculata, Ageratum conyzoides, and Crassocephalum crepidiodes and to predict the chemical compounds that have a role as antibacterial. The samples were extracted with water and further fractionated using chloroform in the laboratory. Extracts determined the phytochemical compounds, antibacterial activity diffusion method, and compounds that have a role as antibacterial through literature review. Acmella paniculata demonstrated high antibacterial activities with the highest diameter of the zones of inhibition with a concentration of just 0.5 mg/disc. The compound that seems to have a role in antibacterial activity is spilanthol.

Meta-Analysis: Effect of Cigarette Smoke Exposure on Pregnant Women as Passive Smokers on Low Birth Weight Kusumaningtiyas, Zonna Aditiya; Ryadi, Yusuf
Journal of Epidemiology and Public Health Vol. 7 No. 2 (2022)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/jepublichealth.2022.07.02.08

Background: Intrauterine exposure to tobacco smoke is considered an important risk factor for low birth weight (LBW) infants, low birth weight (SGA) infants, and preterm delivery. Mothers who smoke during pregnancy are known to limit intrauterine fetal growth and result in low birth weight. This study aims to analyze the effect of exposure to cigarette smoke on pregnant women as active smokers on the incidence of low birth weight.Subjects and Method: This research is a meta-analysis study using PRISMA flowchart guidelines. The article search process was carried out between 2013-2021 using databases from PubMed, Google Scholar and Science Direct PICO, namely, population= pregnant women. Intervention= exposure to cigarette smoke. Comparison= not exposed to cigarette smoke. Outcome= low birth weight. The keywords used for the article search were “Pregnant or pregnancy” AND “smoking” AND “birth weight”. The analysis was carried out using RevMan 5.3 software.Results: There are 8 primary studies spread across 4 continents, namely the continents of Australia, South America, Asia, and Europe, which were selected for a systematic review and meta-analysis. The data found showed that exposure to cigarette smoke in pregnant women as passive smokers increased 2.01 times low birth weight compared to pregnant women who were not exposed to cigarettes (aOR= 2.01; 95% CI= 1.32 to 3.06; p<0.001).Conclusion: Exposure to cigarette smoke in pregnant women as passive smokers increases the risk of low birth weight. Keywords: Low birth weight (LBW), cigarette exposure Correspondence:Zonna Aditiya Kusumaningtiyas. Diploma IV of Midwifery, Health Polytechnics Ministry of Health, Surabaya. Jl. Pucang Jajar Tengah 56, Surabaya, East Java. Email: zonnaaditiya22@gmail.com. Mobile: +62-822-3499-8054.

Meta-Analysis: The Effect of D-Dimer on Mortality in Patients with COVID-19 Ryadi, Yusuf; Rahardjo, Setyo Sri; Ichsan, Burhannuddin
Journal of Epidemiology and Public Health Vol. 7 No. 4 (2022)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/jepublichealth.2022.07.04.11

Background: The severity of COVID-19 can be detected by examining elevated levels of CRP, ferritin, IL-6 and LDH. Elevated D-dimer levels are often found in patients with severe COVID-19 which can predict the occurrence of ARDS (Acute Respiratory Distress Syndrome) and patient mortality. The purpose of this study was to determine how much influence D-dimer levels had on mortality of COVID-19 patients. Subjects and Method: This study used a systematic review and meta-analysis with following PICO, population: patients with a clinical diagnosis of COVID-19. Intervention: high D-dimer level. Comparison: low D-dimer level. Outcome: mortality. The data used were obtained from scientific research articles from Pubmed, Google Scholar, Science Direct, and Proquest electronic databases with a cohort design in 2020 until 2022 and report on aOR in multivariate analysis. The keywords used in the search for scientific articles were “D-dimer level” OR “D-dimer” AND “COVID-19” AND “mortality”. The selection of articles is done by using PRISMA flow diagram. Data were analyzed using Review Manager software version 5.4.1.Results: A total of 12 studies with a cohort design that met the criteria from Asia, America, and Europe were selected for a systematic review and meta-analysis. Based on the meta-analysis, it was found that increased levels of D-dimer (>0.5 g/mL) increased mortality in COVID-19 patients by 6.40 times compared to low levels of D-dimer (≤0.5 g/mL) and was statistically significant (aOR = 6.40; 95% CI= 4.51 to 9.08; p<0.001).Conclusion: Elevated levels of D-dimer may increase mortality risk in COVID-19 patients. Keywords: d-dimer level, d-dimer, covid-19, mortality. Correspondence:Yusuf Ryadi. Masters Program in Public Health, Universitas Sebelas Maret. Jl. Ir. Sutami 36A, Surakarta 57126, Jawa Tengah. Email: yusuf.ryadi@gmail.com. Mobile: 085715605268.

Sekolah Keluarga Berkualitas: Pencegahan Stunting di Kabupaten Sukabumi Herawati, Tin; Hastuti, Dwi; Yuliati, Lilik Noor; Ryadi, Yusuf; Asikin, Munawar
Jurnal Pengabdian Inovasi Masyarakat Indonesia Vol. 4 No. 2 (2025): Edisi Agustus
Publisher : Program Studi Pendidikan Kimia FKIP Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jpimi.v4i2.6284

Human resources are the primary capital in national development and the most important aspect needed to advance a nation. The issue of stunting in Indonesia poses a threat to the development of quality human resources. Families play a crucial role in contributing to societal issues, including stunting. Family empowerment through the Quality Family School aims to provide education to mothers with young children and pregnant women. This program was implemented in two locations: Gede Pangrango Village and Sukamanis Village. A total of 100 participants attended the school. The results of the activity showed an increase in participants' knowledge regarding family resilience, parenting, financial management, child value investment, and family functions.

Meta-Analysis: Effect of Cigarette Smoke Exposure on Pregnant Women as Passive Smokers on Low Birth Weight Kusumaningtiyas, Zonna Aditiya; Ryadi, Yusuf
Journal of Epidemiology and Public Health Vol. 7 No. 2 (2022)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Background: Intrauterine exposure to tobacco smoke is considered an important risk factor for low birth weight (LBW) infants, low birth weight (SGA) infants, and preterm delivery. Mothers who smoke during pregnancy are known to limit intrauterine fetal growth and result in low birth weight. This study aims to analyze the effect of exposure to cigarette smoke on pregnant women as active smokers on the incidence of low birth weight.Subjects and Method: This research is a meta-analysis study using PRISMA flowchart guidelines. The article search process was carried out between 2013-2021 using databases from PubMed, Google Scholar and Science Direct PICO, namely, population= pregnant women. Intervention= exposure to cigarette smoke. Comparison= not exposed to cigarette smoke. Outcome= low birth weight. The keywords used for the article search were “Pregnant or pregnancy” AND “smoking” AND “birth weight”. The analysis was carried out using RevMan 5.3 software.Results: There are 8 primary studies spread across 4 continents, namely the continents of Australia, South America, Asia, and Europe, which were selected for a systematic review and meta-analysis. The data found showed that exposure to cigarette smoke in pregnant women as passive smokers increased 2.01 times low birth weight compared to pregnant women who were not exposed to cigarettes (aOR= 2.01; 95% CI= 1.32 to 3.06; p<0.001).Conclusion: Exposure to cigarette smoke in pregnant women as passive smokers increases the risk of low birth weight. Keywords: Low birth weight (LBW), cigarette exposure Correspondence:Zonna Aditiya Kusumaningtiyas. Diploma IV of Midwifery, Health Polytechnics Ministry of Health, Surabaya. Jl. Pucang Jajar Tengah 56, Surabaya, East Java. Email: zonnaaditiya22@gmail.com. Mobile: +62-822-3499-8054.

Exploration of Wedelia trilobata, Acmella paniculata, Ageratum conyzoides, and Crassocephalum crepidiodes as Antibacterial Plants Ryadi, Yusuf; Alzamori, Winda; Batubara, Irmanida; Suparto, Irma Herawati
Jurnal Jamu Indonesia Vol. 8 No. 3 (2023): Jurnal Jamu Indonesia
Publisher : Tropical Biopharmaca Research Center, IPB University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/jji.v8i3.347

Some Asteraceae plants are reported to contain phytochemicals and to show high antibacterial activity. This study aims to determine the highest antibacterial activity of Wedelia trilobata, Acmella paniculata, Ageratum conyzoides, and Crassocephalum crepidiodes and to predict the chemical compounds that have a role as antibacterial. The samples were extracted with water and further fractionated using chloroform in the laboratory. Extracts determined the phytochemical compounds, antibacterial activity diffusion method, and compounds that have a role as antibacterial through literature review. Acmella paniculata demonstrated high antibacterial activities with the highest diameter of the zones of inhibition with a concentration of just 0.5 mg/disc. The compound that seems to have a role in antibacterial activity is spilanthol.

Farmers’ Perceptions and Experiences on Family Nutrition Fulfillment and Mental Health Management in Rural Indonesia Ryadi, Yusuf; Dewi, Mira; Hartini, Rianti Sri; Ichsan, Burhannudin; Aryoseto, Lukman
Jurnal Medis Islam Internasional Vol 7 No 2 (2025): December
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/iimj.v7i2.7650

Introduction: Farmers in rural Indonesia face challenges in maintaining nutritional adequacy and mental health due to economic instability, crop failure risks, and fluctuating commodity prices. Limited empirical evidence exists on how these factors intersect within farming communities. Objective: This study aims to explore farmers' perceptions and experiences regarding nutrition and mental health among farmer groups in three rural districts of Indonesia. Methods: A qualitative study was conducted with 36 farmers (aged 25–65 years; all males) from Kulonprogo, Boyolali, and Bogor, selected purposively. Data were collected through focus group discussions and analyzed using inductive qualitative content analysis based on Graneheim and Lundman’s framework and processed with enVivo® software. Results: The main stressors identified were economic hardship, crop failure, debt and unstable commodity prices. Food decision-making was largely determined by wives, with children’s needs prioritized. While severe food insecurity was not reported, mild to moderate food insecurity characterized by limited dietary diversity was common. Coping strategies included additional income-generating activities, utilizing homegrown produce, and borrowing from relatives or neighbors. Conclusions: Findings indicate a strong interrelation between food insecurity and mental distress among farmers. Interventions that integrate nutrition improvement and mental health support alongside economic and agricultural policy reforms are essential to enhance farmers’ well-being.

Title

Found 8 Documents
Search

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Title Search

Found 8 Documents Search

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Title

Found 8 Documents
Search