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All Journal Journal of Food and Pharmaceutical Science Pharmaciana: Jurnal Kefarmasian Majalah Farmaseutik Media Ilmu Kesehatan Journal of Innovation in Community Empowerment (JICE) Journal of Pharmaceutical (JOP) Journal of Food and Pharmaceutical Sciences
Leswara, Dianita Febrina
Universitas Jenderal Achmad Yani Yogyakarta
Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Environmental Science Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences

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Uji Aktivitas Antibakteri Infusa Kayu Secang (Caesalpinia Sappan L.) Terhadap Bakteri Escherichia coli ATCC 25922 dan Staphylococcus aureus ATCC 25923 Leswara, Dianita Febrina; Nurhasanah, Devika; Retno P., Maysi
JOURNAL OF PHARMACEUTICAL (JOP) Vol. 2 No. 2 (2024): Journal of Pharmaceutical (JOP)
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat (LPPM) UNIVERSITAS JENDERAL ACHMAD YANI YOGYAKARTA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30989/jop.v2i2.1460

Abstract

Background: Escherichia coli and Staphylococcus aureus are two common types of bacteria that can cause infections in the human body. The treatment to overcome infections caused by Escherichia coli and Staphylococcus aureus bacteria is by administering antibiotics. The use of antibiotics that are not appropriate or not according to instructions can cause resistance so that alternative antibacterial agents from herbal plants begin to be developed. One of the plants known to contain antibacterial compounds is the secang plant. The secang wood stem is known to contain flavonoid and tannin antibacterial compounds.  Objective: To determine the bacterial activity and Minimum Inhibitory Concentration (MIC) of secang wood infusa (Caesalpinia sappan L.) against Escherichia coli and Staphylococcus aureus. Method: Extraction of active compounds in secang wood was done by infundation method. The concentration of secang wood infusion that will be tested is 25%, 50%, 75% and 100%. Testing the antibacterial activity of secang wood infusion was carried out against Escherichia coli and Staphylococcus aureus using the well diffusion method. Results: Extraction of active compounds in secang wood is carried out using the infundation method. All concentrations of secang wood infusion tested 25%, 50%, 75% and 100%, showed antibacterial activity against Escherichia coli ATCC 25922 and Staphylococcus aureus ATCC 25923. The smallest concentration that showed inhibition of antibacterial activity was at a concentration of 25% with diameter of of inhibition zone is 20.52 mm in Escherichia coli ATCC 25922 and 20.58 mm in Staphylococcus aureus ATCC 25923 bacteria. Conclusion: Secang wood infusion has antibacterial activity with Minimum Inhibitory Concentration (MIC) at 25% concentration with strong inhibition
Penerapan Response Surface Methodology dalam Optimasi Proses Ekstraksi dari Artemisia vulgaris Terhadap Nilai Rendemen Kurniasih, Kholif Sholehah Indra; Firdausia, Rizqa Salsabila; Leswara, Dianita Febrina; Nurhayati, Adela; Febriana, Siti Zahara
Majalah Farmaseutik Vol 21, No 2 (2025)
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/farmaseutik.v21i2.101817

Abstract

Dalam beberapa tahun terakhir, telah terjadi peningkatan terhadap penggunaan bahan alam sebagai senyawa dalam proses pembuatan obat. Penggunaan bahan alam mempunyai efek samping yang cenderung lebih kecil dibandingkan dengan obat sintetik. Artemisia vulgaris memiliki kandungan metabolit sekunder yang dapat dijadikan sebagai kandidat obat bahan alam. Dalam mengisolasi senyawa metabolit tersebut diperlukan kondisi ekstraksi yang optimal untuk memberikan efek yang maksimal. Tujuan dari penelitian ini adalah melakukan optimasi kondisi proses ekstraksi pada Artemisia vulgaris sehingga diperoleh ukuran partikel, waktu maserasi serta konsentrasi pelarut yang optimal dalam mengisolasi metabolit sekunder berdasarkan atas nilai rendemen. Program Minitab 17 dengan Response Surface Methodology Box-Behnken Design digunakan dalam penelitian ini untuk memilih kondisi proses ekstraksi berdasarkan faktor-faktor yang dapat memberikan respon maksimal. Penelitian ini dilakukan dengan menggunakan variasi ukuran partikel 40, 60, dan 80 mesh, waktu maserasi 12, 24, dan 36 jam, serta variasi konsentrasi pelarut etanol 50%, 70%, dan 90%. Hasil analisis menunjukkan bahwa perbedaan nomer ayakan, waktu maserasi, dan konsentrasi pelarut dapat mempengaruhi %rendemen yang diperoleh. Diketahui nilai rendemen menggunakan nomer ayakan 40, waktu maserasi 24 jam serta konsentrasi etanol 90% memiliki %rendemen yang rendah, yaitu 0,715% jika dibandingkan dengan nomer ayakan 80, waktu maserasi 24 jam, dan konsentrasi pelarut 50% yaitu 3,42%.
Pemberdayaan Ibu Rumah Tangga Dalam Pemanfaatan Tanaman Obat Keluarga (TOGA) Leswara, Dianita Febrina; Mufrod; Kurniasih, Kholif Sholehah Indra
The Journal of Innovation in Community Empowerment Vol 6 No 1 (2024): Journal of Innovation in Community Empowerment (JICE)
Publisher : Universitas Jenderal Achmad Yani Yogyakarta

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Abstract

ABSTRACT. Indonesian have used plants as traditional medicine to treat health problems. In general, the use of traditional medicine is considered safer than the use of modern medicine. This is because traditional medicine has relatively fewer side effects than modern medicine. However, it is still necessary to use traditional medicines accurately to minimize side effects. Empowering housewives in using Family Medicinal Plants can be used to support improving family welfare and health. For this reason, this service activity aims to: (1) increase knowledge about the scientific properties of Family Medicinal Plants among housewives, (2) increase knowledge about the procedures for planting Family Medicinal Plants among housewives, and (3) improve skills for processing Family Medicinal Plants among housewives. stairs so that it can be beneficial for health. Service activities are carried out using the lecture method to explain the scientific benefits of Family Medicinal Plants, planting Family Medicinal Plants, and processing Family Medicinal Plants. Overall service activities can be said to be good and successful, seen from the success of the target number of training participants, achievement of training objectives, achievement of planned material targets, and participant's ability to master the material to meet predetermined targets. The Empowerment of Housewives in the Use of Family Medicinal Plants community service program in Pangkah Hamlet, Bantul, Yogyakarta was able to increase participants' interest and knowledge regarding the use of family medicinal plants. KEYWORDS: Herbal; Housewife; family medicinal plants
PENINGKATAN PENGETAHUAN SEBAGAI UPAYA PENCEGAHAN STUNTING DI DUKUH MEDELAN, KECAMATAN SUMBERAGUNG Nurjanah, Miftah; Nurjanah, Baiti; Reza, Fahmi; Febriyanti, Isna; Zahra , Afifah Aulia; Rahmawati, Nisa; Ulya, Rahmatika; Desnaya, Salma; Agustin, Tia Nanda; Pratiwi, Widia; Leswara, Dianita Febrina
The Journal of Innovation in Community Empowerment Vol 7 No 1 (2025): Journal of Innovation in Community Empowerment (JICE)
Publisher : Universitas Jenderal Achmad Yani Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30989/jice.v7i1.1441

Abstract

Stunting is a condition of growth failure in children caused by inadequate nutritional intake, recurrent infections, and lack of psychosocial stimulation. This problem remains a major public health issue in various regions of Indonesia, including Padukuhan Medelan, Sumberagung District. Based on preliminary observations, the community in this area still has a low level of knowledge regarding the causes and prevention of stunting. This indicates a gap between the community’s need for information and their understanding of stunting. This community service activity aimed to improve public knowledge related to stunting and its prevention efforts. The educational activity on stunting prevention in Padukuhan Medelan was attended by local residents. The implementation method used an interactive lecture approach, which included the delivery of materials on definitions, causative factors, impacts, and stunting prevention strategies, accompanied by a discussion session to deepen participants’ understanding. The results showed an increase in participants’ knowledge about stunting, as evidenced by their active participation during the activity and the achievement of all planned material targets. Overall, the program was well implemented and effective. It is recommended that this program be continued periodically by involving health workers and local government officials to strengthen stunting prevention efforts at the community level
Co-Authors Agustin, Tia Nanda Desnaya, Salma Devika Nurhasanah Dwi Larasati Dwi Larasati, Dwi Enggrainia, Bella Febriana, Siti Zahara Febriyanti, Isna Kintoko, Kintoko Kurniasih Kurniasih, Kholif Sholehah Indra Mufrod Mufrod Nanik Sulistyani Niken Larasati Nisa Rahmawati, Nisa Nurhayati, Adela Nurjanah, Baiti Nurjanah, Miftah Pratama, Nofran Putra Retno P., Maysi Reza, Fahmi Rizqa Salsabila Firdausia Sholehah I, Kholif Ulya, Rahmatika Widia Pratiwi, Widia Zahra , Afifah Aulia