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Pengujian Potensi Diuretik Infusa Daun Bangun-Bangun (Plectranthus Amboinicus (Lour.) Spreng) Yang Diujikan Pada Tikus Jantan (Rattus Norvegicus Berkenhout) Galur Wistar Monica Suryani; Jon Kenedy Marpaung; Suharyanisa Suharyanisa; Mestika Lumbantoruan
Jurnal Ilmu Kesehatan dan Gizi Vol. 1 No. 3 (2023): Juli: Jurnal Imu Kesehatan dan Gizi
Publisher : Pusat Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jikg.v1i3.1730

Abstract

Diuretics act on the kidneys to increase the excretion of water and sodium chloride. The working principle of diuretics in general is to reduce electrolyte reabsorption by the renal tubules, where an increase in electrolyte excretion will be accompanied by an increase in water excretion which is needed to achieve osmotic balance. Bangun-Bangun leaf contains polyphenolic compounds, saponins, glycosides, flavonoids, and essential oils. Bangun-Bangun leaves types of flavonoids, namely quercetin, apigenin, luteolin, salvigenin, and genkwanin. Apigenin is known as a compound that functions as a diuretic. IDBB was obtained from the infusion technique with distilled water and then the infusion was used on 25 diuretic rats which were divided into 5 groups. Group I (negative) Na-CMC 0.5%, group II, III, IV, IDBB doses of 10, 20, 40%, and group V (positive) Furosemide 3.6 mg/kgBW were given orally. Rats were given aquadest orally at a dose of 15 ml/kgBW. Mice were placed in metabolic cages, then a physical examination of urine was carried out every 1 hour for 6 hours. The results showed that the IDK with the best dose was 40% which gave an increase in urine volume, had an effect on urine pH, had an effect on urine specific gravity, had an effect on urine color, and had an effect on urine clarity.
Sosialisasi Dampak Bencana Banjir Dan Dagusibu Antibiotik Di Kecamatan Tamiang Hulu, Kabupaten Aceh Tamiang Dhea Nur Fadhilah; Suharyanisa Suharyanisa; Dumartina Hutauruk; Siti Nurbaya
Jurnal Pengabdian Masyarakat Indonesia Sejahtera Vol. 2 No. 1 (2023): Maret : Jurnal Pengabdian Masyarakat Indonesia Sejahtera
Publisher : STAI YPIQ BAUBAU, SULAWESI TENGGARA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59059/jpmis.v2i1.93

Abstract

Indonesia merupakan salah satu negara yang berlokasi di wilayah yang rawan terhadap berbagai kejadian bencana alam. Banjir merupakan bencana yang setiap tahun terjadi di Indonesia dan berbagai kejadian banjir terbukti berdampak pada kehidupan manusia dan lingkunganya terutama dampaknya terhadap kesehatan masyarakat yang terkena banjir. Penyakit yang dialami biasanya berupa diare, demam, dan gatal-gatal pada kulit yang disebabkan oleh bakteri, virus maupun patogen lainnya. Tujuan kegiatan pengabdian ini adalah untuk memberikan sosialisasi tentang bahaya banjir dan pengenalan tentang antibiotik kepada masyarakat, sehingga penyakit dampak banjir khususnya diare dapat teratasi dengan baik, kegiatan ini dilakukan oleh tim Dosen Universitas Sari Mutiara dengan melakukan edukasi mengenai Dapatkan Gunakan Simpan dan Buang (DAGUSIBU) Antibiotik. Metode kegiatan ini melibatkan masayarakat di Kecamatan Tamiang Hulu, Kabupaten Aceh Tamiang adalah ceramah, pembagian leaflet, dan tanya jawab. Ceramah yang disajikan dalam bentuk presentasi power point, pembagian leaflet dalam bentuk brosur dilanjutkan dengan sesi diskusi atau tanya jawab tentang DAGUSIBU Antibiotik. Hasil dari kegiatan ini adalah di Kecamatan Tamiang Hulu, Kabupaten Aceh Tamiang mendapatkan edukasi terkait Sosialisasi Bahaya Banjir dan DAGUSIBU (dapatkan, gunakan, simpan, dan buang) antibiotik.
Edukasi Kepada Masyarakat Daun Pegagan Berkhasiat Sebagai Pelembab Wajah Monica Suryani; Suharyanisa Suharyanisa; Ferdinand Paulus Ginting; Syarifah Roslianizar; Widya Fitri
Faedah : Jurnal Hasil Kegiatan Pengabdian Masyarakat Indonesia Vol. 2 No. 3 (2024): Jurnal Hasil Kegiatan Pengabdian Masyarakat Indonesia
Publisher : FKIP, Universitas Palangka Raya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59024/faedah.v2i3.968

Abstract

Gotu kola leaves have active compounds in the form of alkaloids, flavonoids, saponins, and tannins, which are secondary metabolites. A sheet mask is a more practical facial care cosmetic preparation without rinsing, effectively moisturizing facial skin. This service aims to provide education to the public about the benefits of gotu kola leaves as a natural facial moisturizer. This community service activity is carried out using an outreach method to the community individually using material presentations using power points and print media in Langkat. The results of implementing this educational activity have increased the insight and knowledge of the participants, especially children, teenagers, and mothers, in the form of using clove leaves as a herbal plant to overcome hair growth problems. The results of the participants' knowledge level from the pre-test and post-test scores are in the good category. Previously, people did not know the benefits of gotu kola leaves, which are efficacious as a natural facial moisturizer; now people can use them.
Sosialisai Tentang Pentingnya Penanaman Tanaman Obat Untuk Mewujudkan Masyarakat Sehat Di Kecamatan Medan Helvetia, Kota Medan Dhea Nur Fadhilah; Suharyanisa Suharyanisa; Jon Kenedy Marpaung; Juli Susanti
Natural: Jurnal Pelaksanaan Pengabdian Bergerak bersama Masyarakat. Vol. 1 No. 4 (2023): November : Natural: Jurnal Pelaksanaan Pengabdian Bergerak bersama Masyarakat
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/natural.v1i4.248

Abstract

Medicinal plants are plants with positive pharmacological effects on the human body and are usually grown on a home or communal scale. These medicinal plants can then be used as traditional medicine which can be made easily. The plants chosen are usually plants that can be used to treat simple health problems such as flu and coughs. Medicinal plants can increase the body's immunity because they can prevent disease through the secondary metabolites they contain. In this service activity, two activities were carried out separately, namely socialization and planting medicinal plants with residents. The outreach was carried out to provide information to the residents of Medan Helvetia District regarding medicinal plants so that these medicinal plants can be useful after being planted. Planting is also carried out to increase awareness regarding land use, as well as being a starting point for residents in cultivating medicinal plants. This socialization on the use of family medicinal plants aims to provide information to the people of Kexamatan Medan Helvetia in using medicinal plants. It is hoped that this community service activity will help increase public knowledge about the importance of planting and utilizing medicinal plants to create a healthy society.
Edukasi Pemanfaatan Biji Nangka Berkhasiat sebagai Antibakteri Suharyanisa Suharyanisa; Jon Kenedy Marpaung; Julia Susanti
Natural: Jurnal Pelaksanaan Pengabdian Bergerak bersama Masyarakat. Vol. 2 No. 3 (2024): August : Natural: Jurnal Pelaksanaan Pengabdian Bergerak bersama Masyarakat
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/natural.v2i3.653

Abstract

Jackfruit seeds contain several secondary metabolite compounds, including flavonoids, alkaloids, saponins, terpenoids and steroids. Jackfruit plants are one type of plant that can grow in tropical areas, so it is easy to find in Indonesia. The purpose of this community service is to improve and provide information and education to the community that the use of jackfruit seeds can be efficacious as an antibacterial. The results of the implementation of community service programs in the form of counseling to the community that there are benefits of jackfruit seeds used as antibacterial. So far, the public does not know that jackfruit seeds, which are often thrown away, can be efficacious as an antibacterial. The conclusion that the counseling was carried out according to the implementation and plan, received a good response from the surrounding community, the community also got information and knowledge and could apply the information for the family.
Formulasi dan Uji Aktivitas Antibakteri Sediaan Gel Antijerawat Ekstrak Etanol Daun Sisik Naga (Drymoglossum piloselloides (L.) Pressl.) terhadap Staphylococcus aureus Suharyanisa Suharyanisa; Widya Fitri; Nuranti Rumela; Betharina br Tarigan
Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF) Vol. 2 No. 4 (2024): Oktober: Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF)
Publisher : LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/jrikuf.v2i4.560

Abstract

Acne appears due to increased sebum production on the skin and the growth of Staphylococcus aureus bacteria. The antibacterial activity of ethanol extract of dragon scale leaves (EEDSL) against Staphylococcus aureus bacteria provides strong inhibitory power. Dragon scale leaves (Drymoglossum piloselloides(L.) Pressl.)) can act as an anti-acne and its use as a preparation has not been widely carried out. This study aims to determine that EEDSL can be formulated as a gel preparation that meets the physicochemical quality requirements and that EEDSL gel preparations have antibacterial activity against Staphylococcus aureus. This study was conducted using an experimental method, sampling using the purposive sampling method in Kidupen Village, Juhar District, Karo Regency. Dragon scale leaf extract was obtained using the maceration technique with an ethanol solvent. EEDSL was formulated into a gel and then subjected to physical evaluation tests and antibacterial tests on staphylococcus aureus bacteria by looking at the diameter of the inhibitory power formed. The results of the study showed that the formulation of the anti-acne gel preparation was colorless, clear, and odorless obtained at F0. At F1; F2; and F3, a brown gel preparation was obtained with a semi-solid form and a distinctive EEDSL smell. The antibacterial activity test of EEDSL against Staphylococcus aureus showed an average value ± SD of the inhibition zone in each formula, namely at F0: 0.00 ± 0.00 mm; F1: 6.86 ± 0.17 mm; F2: 8.46 ± 0.19 mm; F3: 9.17 ± 0.18 mm; and positive control: 14.09 ± 0.23 mm. Based on the results of the data obtained, it can be concluded that EEDSL can be formulated as a gel preparation that meets the physicochemical quality requirements. Each concentration of ethanol extract of dragon scale leaves (Drymoglossum piloselloides (L.) Pressl.) has antibacterial activity against Staphylococcus aureus with a medium category.
Pemberdayaan Masyarakat Melalui Pelatihan Pembuatan Sediaan Gel Antijerawat Berbahan Herbal Lokal Suharyanisa Suharyanisa; Widya Fitri; Nuranti Rumela; Betharina br Tarigan
Compromise Journal Community Proffesional Service Journal Vol. 3 No. 1 (2025): Compromise Journal : Community Proffesional Service Journal
Publisher : LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/compromisejournal.v3i1.562

Abstract

Acne is a common skin problem caused by excessive growth of Staphylococcus aureus on the skin due to increased sebum production. Dragon scale leaves (Drymoglossum piloselloides) contain active compounds such as saponins, phenols, tannins, and flavonoids, which have antibacterial and anti-inflammatory properties. This community service program aims to enhance public knowledge about the utilization of dragon scale leaf extract in acne gel formulations. The activities included education, a demonstration of gel preparation, and an evaluation of training effectiveness through pre-tests and post-tests. The evaluation results showed an increase in participant understanding from 20% to 75%, exceeding the targeted improvement. Active community participation indicates a strong interest in utilizing herbal plants as an alternative skincare solution, highlighting the potential for further development.
Edukasi Pemanfaatan Daun Kapulaga terhadap Tambak Udang di Desa Sikhorilafau Dumartina Hutauruk; Manahan Situmorang; Suharyanisa Suharyanisa; Yanti Musyawarah
Jurnal Nusantara Berbakti Vol. 3 No. 2 (2025): April: Jurnal Nusantara Berbakti
Publisher : Universitas Kristen Indonesia Toraja

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59024/jnb.v3i2.641

Abstract

The many negative effects on the use of chemical-based medicine have made researchers increasingly interested in looking for alternative natural ingredients that have high therapeutic potential and minimal side effects. One of the plants that is often used as a medicinal ingredient is cardamom (Amomum cardamomum L.), which comes from the Zingiberaceae family. Cardamom has been widely used by the community as an aromatic, carmimental (reducing gas in the stomach), cough medicine, mouth freshener, and various other traditional medicines. The content of bioactive compounds such as alkaloids, flavonoids, tannins, and saponins in cardamom is believed to play an important role in providing pharmacological effects. This study aims to analyze the bioactivity level of toxicity of cardamom leaf ethanol extract against shrimp larvae Artemia salina L. using the Brine Shrimp Lethality Test (BSLT) method and determine the LC₅₀ value as a toxicity parameter. The research method used an experimental quantitative approach with six treatment concentrations, namely 25 ppm, 50 ppm, 100 ppm, 200 ppm, 500 ppm, and 1000 ppm, as well as one negative control. Each treatment was replicated five times to get accurate results. A total of 350 Artemia salina larvae were used, with 10 larvae for each concentration test. Larval mortality was calculated after 24 hours of treatment to determine the potential toxicity of the extract. In addition to laboratory research, community service programs are carried out to increase coastal communities' understanding of the use of cardamom leaves for pond shrimp larvae. This education is important because the results of the research are expected to be the basis for the use of natural materials that are safer, more environmentally friendly, and sustainable in the management of shrimp ponds.
Uji Aktivitas Antibakteri Ekstrak Etanol Biji Nangka (Artocarpus Heterophyllus) Terhadap Bakteri Shigella Dysentriae dan Staphylococcus Epidermidis Suharyanisa Suharyanisa; Jon Kenedy Marpaung; Julia Susanti
Inovasi Kesehatan Global Vol. 1 No. 3 (2024): Agustus : Inovasi Kesehatan Global
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62383/ikg.v1i3.673

Abstract

Jackfruit seeds contain several secondary metabolites, including flavonoids, alkaloids, saponins, terpenoids, and steroids. The jackfruit tree is a tropical plant commonly found in Indonesia. This study aimed to determine whether extracts from jackfruit seeds have antibacterial activity against Shigella dysenteriae and Staphylococcus epidermidis. The antibacterial activity was tested using the discdiffusion method with concentrations of 10%, 15%, and 20%.The research results indicated that the diameter of the inhibition zone against Shigella dysenteriae at 10% concentration was 13.15 mm, at 15% concentration was 15.9 mm, and at 20% concentration was 19.08 mm. For Staphylococcus epidermidis, the inhibition zone diameters were 10.5 mm at 10% concentration, 13.1 mm at 15% concentration, and 13.7 mm at 20% concentration. The results demonstrated that as the concentration of ethanol extract from jackfruit seeds increased, the inhibition zones around the discs also increased. This was attributed to the varying volumes of ethanol extract present at each concentration level.It was found that the ethanol extract from jackfruit seeds exhibited strong inhibitory effects against both Shigella dysenteriae and Staphylococcus epidermidis bacteria.
Formulasi Sediaan Sheet Mask Ekstrak Etanol Daun Pegagan (Centella asiatica (L.) Urb) sebagai Pelembab Kulit Wajah Monica Suryani; Suharyanisa Suharyanisa; Ferdinand Paulus Ginting; Syarifah Roslianizar; Widya Fitri
Inovasi Kesehatan Global Vol. 1 No. 3 (2024): Agustus : Inovasi Kesehatan Global
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62383/ikg.v1i3.689

Abstract

Centella asiatica leaves contain active compounds such as alkaloids, flavonoids, saponins, and tannins, which are secondary metabolites. A sheet mask is a practical cosmetic facial treatment that does not require rinsing and is effective in moisturizing the skin. This study aims to determine the formulation of a sheet mask preparation. The ethanol extract of Centella asiatica leaves meets the physical quality evaluation criteria for the preparation. The experimental formulation method involves creating a sheet mask composed of various components including Centella asiatica leaf extract, glycerin, propylene glycol, xanthan gum, PEG-40 hydrogenated castor oil, nipagin, 96% ethanol, fragrance (Green tea), aquadest, sheet mask base, and foil bag. The research includes the characterization of the raw material, phytochemical screening of the extract, and formulation into sheet masks with concentrations of 2%, 4%, and 6%, followed by moisturizing testing using a skin analyzer. The evaluation of the preparation includes organoleptic tests, homogeneity, physical stability, viscosity, pH value, irritation testing, and hedonic testing. The characterization results show a water content of 3.46%, water-soluble extract content of 31.38%, ethanol-soluble extract content of 11.96%, total ash content of 8.41%, and acid-insoluble ash content of 1.09%. Phytochemical screening results show positive for alkaloids, flavonoids, saponins, tannins, and steroids. The study indicates that the ethanol extract of Centella asiatica can be formulated into a homogeneous and stable sheet mask preparation. The pH of the preparation meets the requirement with a value of 4.5-6.5, which is relatively safe for facial skin. The preparation does not cause irritation, with viscosity testing meeting the requirement of 250-1150 cp. The moisturizing test shows that a 6% Centella asiatica extract concentration provides the best moisturizing effect, and the most preferred formulation is F3 with a preference percentage of 38.12%. The average moisture values are F0 (Blank) 25.64%, F1 (2%) 33.26%, F2 (4%) 39.18%, and F3 (6%) 38.12%. Overall, it can be concluded that Centella asiatica extract can be formulated into a sheet mask with effective moisturizing capability for the facial skin.