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Pengujian Potensi Diuretik Infusa Daun Bangun-Bangun (Plectranthus Amboinicus (Lour.) Spreng) Yang Diujikan Pada Tikus Jantan (Rattus Norvegicus Berkenhout) Galur Wistar Monica Suryani; Jon Kenedy Marpaung; Suharyanisa Suharyanisa; Mestika Lumbantoruan
Jurnal Ilmu Kesehatan dan Gizi Vol. 1 No. 3 (2023): Juli: Jurnal Imu Kesehatan dan Gizi
Publisher : Pusat Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jikg.v1i3.1730

Abstract

Diuretics act on the kidneys to increase the excretion of water and sodium chloride. The working principle of diuretics in general is to reduce electrolyte reabsorption by the renal tubules, where an increase in electrolyte excretion will be accompanied by an increase in water excretion which is needed to achieve osmotic balance. Bangun-Bangun leaf contains polyphenolic compounds, saponins, glycosides, flavonoids, and essential oils. Bangun-Bangun leaves types of flavonoids, namely quercetin, apigenin, luteolin, salvigenin, and genkwanin. Apigenin is known as a compound that functions as a diuretic. IDBB was obtained from the infusion technique with distilled water and then the infusion was used on 25 diuretic rats which were divided into 5 groups. Group I (negative) Na-CMC 0.5%, group II, III, IV, IDBB doses of 10, 20, 40%, and group V (positive) Furosemide 3.6 mg/kgBW were given orally. Rats were given aquadest orally at a dose of 15 ml/kgBW. Mice were placed in metabolic cages, then a physical examination of urine was carried out every 1 hour for 6 hours. The results showed that the IDK with the best dose was 40% which gave an increase in urine volume, had an effect on urine pH, had an effect on urine specific gravity, had an effect on urine color, and had an effect on urine clarity.
BAKTI SOSIAL HISFARMA DAN PERSIT KCK HUBDAM I/BBU HIMPUNAN SEMINAT FARMASI MASYARAKAT PD IAI SUMATRA UTARA Manahan Situmorang; Dumartina Hutahuruk; Jon Kenedy Marpaung; Siti Nurbaya; Natanael Priltius
NUSANTARA Jurnal Pengabdian Kepada Masyarakat Vol. 2 No. 2 (2022): Mei: Jurnal Pengabdian kepada Masyarakat
Publisher : Pusat Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (157.49 KB) | DOI: 10.55606/nusantara.v2i2.223

Abstract

Blood donation activity is the obligation of every community as a form of concern for others. Many people do not know about the health benefits of blood donation. There are even people who are reluctant to donate blood because they are worried about the side effects it causes. In fact, by donating blood, the blood cells in the body are replaced more quickly with new ones. The purpose of this activity was to carry out the HISFARMA Social Service and Persit KCK HUBDAM I/BBU Community Pharmacy Seminate Association PD IAI North Sumatra. This activity was carried out by conducting a site survey with the implementation team, meeting with Representatives of PERSIT KCK HUBDAM I/BBU, Medan, North Sumatra. This activity was opened by the presenter, after that singing the Indonesia Raya anthem, welcoming remarks, followed by blood donation activities, blood sugar checks, a careful echo talk show and ended with a group photo. Implementation of community service in the form of social services in educating the public on the importance of blood donation, blood sugar checks and careful echo talk shows. Health Checkup has many benefits. When donating blood, the blood cells in the body are replaced more quickly with new ones. If you donate blood once every three months, your body will stay healthy. Besides being useful for helping others, blood donation also makes our bodies healthier. So it can be concluded that this activity has a good impact and influence on people's knowledge in carrying out this activity.
Sosialisai Tentang Pentingnya Penanaman Tanaman Obat Untuk Mewujudkan Masyarakat Sehat Di Kecamatan Medan Helvetia, Kota Medan Dhea Nur Fadhilah; Suharyanisa Suharyanisa; Jon Kenedy Marpaung; Juli Susanti
Natural: Jurnal Pelaksanaan Pengabdian Bergerak bersama Masyarakat. Vol. 1 No. 4 (2023): November : Natural: Jurnal Pelaksanaan Pengabdian Bergerak bersama Masyarakat
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/natural.v1i4.248

Abstract

Medicinal plants are plants with positive pharmacological effects on the human body and are usually grown on a home or communal scale. These medicinal plants can then be used as traditional medicine which can be made easily. The plants chosen are usually plants that can be used to treat simple health problems such as flu and coughs. Medicinal plants can increase the body's immunity because they can prevent disease through the secondary metabolites they contain. In this service activity, two activities were carried out separately, namely socialization and planting medicinal plants with residents. The outreach was carried out to provide information to the residents of Medan Helvetia District regarding medicinal plants so that these medicinal plants can be useful after being planted. Planting is also carried out to increase awareness regarding land use, as well as being a starting point for residents in cultivating medicinal plants. This socialization on the use of family medicinal plants aims to provide information to the people of Kexamatan Medan Helvetia in using medicinal plants. It is hoped that this community service activity will help increase public knowledge about the importance of planting and utilizing medicinal plants to create a healthy society.
Edukasi Pemanfaatan Biji Nangka Berkhasiat sebagai Antibakteri Suharyanisa Suharyanisa; Jon Kenedy Marpaung; Julia Susanti
Natural: Jurnal Pelaksanaan Pengabdian Bergerak bersama Masyarakat. Vol. 2 No. 3 (2024): Agustus : Natural: Jurnal Pelaksanaan Pengabdian Bergerak bersama Masyarakat
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/natural.v2i3.653

Abstract

Jackfruit seeds contain several secondary metabolite compounds, including flavonoids, alkaloids, saponins, terpenoids and steroids. Jackfruit plants are one type of plant that can grow in tropical areas, so it is easy to find in Indonesia. The purpose of this community service is to improve and provide information and education to the community that the use of jackfruit seeds can be efficacious as an antibacterial. The results of the implementation of community service programs in the form of counseling to the community that there are benefits of jackfruit seeds used as antibacterial. So far, the public does not know that jackfruit seeds, which are often thrown away, can be efficacious as an antibacterial. The conclusion that the counseling was carried out according to the implementation and plan, received a good response from the surrounding community, the community also got information and knowledge and could apply the information for the family.
Formulasi Sediaan Emulgel Ekstrak Daun Tanaman Leunca (Solanum nigrum) Sebagai Antibakteri Staphylococcus aureus pada Kulit Jon Kenedy Marpaung; Manahan Situmorang; Yanti Musyawarah; Natanael Priltius
Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF) Vol. 2 No. 4 (2024): Oktober: Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF)
Publisher : LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/jrikuf.v2i4.563

Abstract

Emulgel is a moisturizing topical preparation that is able to soften the skin and protect it from damage. The leaves of the leunca plant have antibacterial and anti- inflammatory properties. Staphylococcus aureus is a gram-positive bacteria that can be found on human skin. This research aims to find out whether leunca (solanum nigrum) leaf extract can be formulated into an emulgel preparation that meets physicochemical quality, find out whether the resulting emulgel preparation of leunca leaf extract (solanum nigrum) can act as an antibacterial for staphylococcus and find out whether there are differences in the concentration of leunca leaf extract emulgel preparations. (solanum nigrum) affects its effectiveness as an antibacterial for Staphylococcus. This research method used. This research was carried out experimentally with emulgel preparations from leunca leaf extract with concentrations of 2%, 4% and 6% with emulgel evaluation. Based on the experimental results, it was concluded that leunca (solanum nigrum) leaf extract could be formulated F0, F1, F2 and F3 to meet the Organoleptic Test, Homogeneity Test, pH Test, Adhesion Test, Spreadability Test, Viscosity Test and Irritation Test. The emulgel preparation formulation from leunca (solanum nigrum) leaf extract showed potential as an antibacterial for Staphylococcus aureus with a DDH value greater than 20 mm, namely 20,31 to 21,83.
Pemberdayaan Masyarakat dalam Pembuatan Emulgel Herbal dari Ekstrak Daun Leunca (Solanum Nigrum) sebagai Alternatif Antibakteri Kulit Jon Kenedy Marpaung; Manahan Situmorang; Yanti Musyawarah; Natanael Priltius
jurnal ABDIMAS Indonesia Vol. 2 No. 4 (2024): Desember: Jurnal ABDIMAS Indonesia
Publisher : STIKes Ibnu Sina Ajibarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59841/jurai.v2i4.2363

Abstract

Leunca leaves are rich in bioactive compounds such as tannins, alkaloids, flavonoids, phenols and steroids, making it possible to use them as an antibacterial. This community service aims to empower the community by introducing and involving them in the production of herbal emulgel from Leunca leaf extract (Solanum nigrum), which had potential as a natural antibacterial agent, particularly for skin care. Leunca leaves, rich in bioactive compounds such as alkaloids and flavonoids, had antibacterial properties that can effectively treat skin infections. Through counseling and practical training, the community is taught how to process Leunca leaves into an emulgel formulation that is easy to use and has health benefits. The method of this community service was carried out through presentations, distribution of modules, and demonstrations of emulgel production to the community. Evaluation results showed an increase in community knowledge about the benefits of Leunca leaves as a natural antibacterial agent, with knowledge improving from 15% to 80% after the counseling. It is hoped that this initiative will raise awareness and promote the use of local herbal ingredients in skin care, as well as open up opportunities for herbal-based entrepreneurship that can improve the community's well-being
Edukasi Pemanfaatan Kulit Buah Salak Pondoh terhadap Bakteri Eschericia coli dan Bakteri Salmonella typhi Jon Kenedy Marpaung; Widya Fitri; Julia Susanti; Martin Suhendri; Enjelina Br Sembiring Kembaren
Jurnal Nusantara Berbakti Vol. 3 No. 2 (2025): April: Jurnal Nusantara Berbakti
Publisher : Universitas Kristen Indonesia Toraja

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59024/jnb.v3i2.640

Abstract

Cottage salak (Salacca zalacca (Gaertn.) Voss) is one of the tropical fruits that not only has high nutritional value, but also contains bioactive compounds that have the potential to be natural antibacterial. The skin of the salak pondoh fruit is often considered waste, even though this part is rich in chemical compounds such as flavonoids, saponins, phenols, tannins, alkaloids, chlorogenic acid, ferrulic acid, and protocatetic acid. These compounds are known to have biological activity that is able to inhibit the growth of pathogenic microorganisms. Escherichia coli and Salmonella typhi bacteria are the main causes of diarrhea and typhoid fever that affect many people, especially in areas with poor sanitation. Infection of these two bacteria can cause intestinal tissue damage, dehydration, and even serious complications if not treated immediately. Therefore, efforts to find alternative antibacterial agents from natural ingredients such as salak pondoh bark are important. This study aims to test the effectiveness of ethanol extract of salak pondoh bark against E. coli and S. typhi bacteria. Extraction was carried out by the maceration method using ethanol as a solvent, then continued with testing of antibacterial activity using the disc diffusion method. The concentration of the extract was tested on several variations to determine the minimum concentration capable of providing an optimal buffer zone against both test bacteria. The community service program integrated with this research aims to increase public understanding regarding the potential of salak pondoh skin as a natural antibacterial. Education is carried out through counseling and demonstrations of making simple extracts that can be used to clean household appliances or prevent microbial contamination of foodstuffs. With this approach, it is hoped that the community can use salak pondoh skin waste more productively, while reducing dependence on synthetic chemicals that have the potential to cause side effects.
Uji Aktivitas Antibakteri Ekstrak Etanol Biji Nangka (Artocarpus Heterophyllus) Terhadap Bakteri Shigella Dysentriae dan Staphylococcus Epidermidis Suharyanisa Suharyanisa; Jon Kenedy Marpaung; Julia Susanti
Inovasi Kesehatan Global Vol. 1 No. 3 (2024): Agustus : Inovasi Kesehatan Global
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62383/ikg.v1i3.673

Abstract

Jackfruit seeds contain several secondary metabolites, including flavonoids, alkaloids, saponins, terpenoids, and steroids. The jackfruit tree is a tropical plant commonly found in Indonesia. This study aimed to determine whether extracts from jackfruit seeds have antibacterial activity against Shigella dysenteriae and Staphylococcus epidermidis. The antibacterial activity was tested using the discdiffusion method with concentrations of 10%, 15%, and 20%.The research results indicated that the diameter of the inhibition zone against Shigella dysenteriae at 10% concentration was 13.15 mm, at 15% concentration was 15.9 mm, and at 20% concentration was 19.08 mm. For Staphylococcus epidermidis, the inhibition zone diameters were 10.5 mm at 10% concentration, 13.1 mm at 15% concentration, and 13.7 mm at 20% concentration. The results demonstrated that as the concentration of ethanol extract from jackfruit seeds increased, the inhibition zones around the discs also increased. This was attributed to the varying volumes of ethanol extract present at each concentration level.It was found that the ethanol extract from jackfruit seeds exhibited strong inhibitory effects against both Shigella dysenteriae and Staphylococcus epidermidis bacteria.