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All Journal Medula Jurnal Kreativitas PKM Jurnal Mandala Pharmacon Indonesia Jurnal Pengabdian Kepada Masyarakat (JPKM) Tabikpun Jurnal Abmas Negeri (JAGRI) Sains Medisina Organisms: Journal of Biosciences E-Amal: Jurnal Pengabdian Kepada Masyarakat JPM (Jurnal Pengabdian Masyarakat) Ruwa Jurai
Andrifianie, Femmy
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Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary Other

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Journal : Medula

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SUPLEMENTASI EKSTRAK DAUN KELOR (Moringa oleifera L.) TERHADAP ANEMIA DEFISIENSI BESI: ARTIKEL REVIEW Satria, Dzakiyyah Shoofina Jasmine; Triyandi, Ramadhan; Iqbal, Muhammad; Andrifianie, Femmy
Medula Vol 14 No 2 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i2.929

Abstract

Iron is an important component of hemoglobin. The function of iron, which is as a source of energy for muscles so that it can affect physical endurance and the ability to work in adolescents. Iron deficiency can lead to hematological disorders of anemia. Anemia is a body condition in which the number of red blood cells and oxygen transport capacity is insufficient to meet the physiological needs of the body. Moringa leaves can be used as a substitute for iron tablets, because Moringa leaf powder contains 28 mg of iron. The method used in this writing, is literature review by collecting several research articles. This literature source search uses literature research sources in the form of google scholar and Pubmed. The inclusion criteria from the search, namely research articles using Indonesian and English, articles published within the last 10 years (2013-2023), and discussing the topic of moringa oleifera and anemia. The results of this literature search can be concluded that Moringa oleifera supplementation significantly increases serum iron levels.
Review Article: Pharmacological Activity of Robusta Coffee Plants (Coffee canephora) Virginia, Jesica; Iqbal, Muhammad; Triyandi, Ramadhan; Andrifianie, Femmy
Medula Vol 14 No 4 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i4.1054

Abstract

Coffee canephora or robusta coffee is a tree-shaped cultivated plant belonging to the Rubiaceae family and the Coffea genus. This plant is most widely planted in Indonesia, namely 91% more than Arabica coffee plantations and has great potential in its use as an alternative treatment for various diseases. Robusta coffee contains flavonoids, alkaloids, tannins, saponins and polyphenols. The two main polyphenolic compounds found in coffee are chlorogenic acid and caffeine, which each account for about 90% of all phenols found in coffee. This review article aims to determine the various pharmacological activities found in robusta coffee obtained from experimental studies conducted using electronic databases in the form of Google Scholar, Pubmed, and Mendley. The inclusion criteria in the article search were articles in Indonesian and English published in the last 10 years and the exclusion criteria were articles that could not be accessed in full. The results of the study of 25 articles show that the robusta coffee plant in the seeds, leaves and fruit skin has antibacterial, antioxidant, anticancer, anti-inflammatory, antifungal, antidiabetic, and biolarvicide pharmacological activities.
Penelusuran Potensi Antioksidan Dalam Beragam Ekstrak Daun Tanaman Obat Di Indonesia Mutiara Hati, Nadia; Triyandi, Ramadhan; Wardhana S, Muhammad Fitra; Andrifianie, Femmy; Iqbal, Muhammad
Medula Vol 14 No 5 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i5.1072

Abstract

Antioxidants are substances that are able to absorb or neutralize free molecules, preventing degenerative diseases such as heart disease and cancer by donating electrons to inhibit free radical chain reactions that damage the body. The use of natural medicines is increasingly becoming the main choice in Indonesian society. Even though various types of plants have been used for a long time, their use has not been optimal. In order to summarize and provide information regarding the potential of natural ingredients from various plant extracts which have antioxidant activity, a literature review was carried out. The method used was a database search via Google Scholar for the last 8 years (2015-2023), which produced 170 journals regarding plants with antioxidant activity. Of this number, 20 plants were selected based on the dark green leaves which have antioxidant activity by comparing the IC50 values ​​obtained. Plant extracts contain antioxidant compounds that can fight free radicals, offering a natural alternative to synthetic antioxidants.  Plants with high antioxidant activity often have characteristics such as phytochemical content such as flavonoids, polyphenols, carotenoids, and vitamin C, as well as bright colors such as purple, red, or orange which indicate the content of antioxidant pigments such as anthocyanins, lycopene, or beta-carotene. Apart from that, plants that have a bitter or astringent taste, such as green tea, red grapes, or blueberries, also tend to contain quite high levels of antioxidant compounds, coupled with their habit of growing in harsh or extreme environments and their traditional use in medicine or health supplements.
Review Article: Pharmacological Activities of Red Spinach (Amaranthus tricolor) Hasyimi, Meifia; Iqbal, Muhammad; Andrifianie, Femmy; Triyandi, Ramadhan
Medula Vol 15 No 2 (2025): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v15i2.1381

Abstract

  Red spinach (Amaranthus tricolor) is a leafy vegetable known for its distinctive red or purplish leaves. This plant is widely cultivated as its leaves are edible and packed with essential nutrients beneficial to the body. Red spinach is rich in antioxidants such as beta-carotene and vitamin C, along with vital minerals like iron, calcium, magnesium, phosphorus, and potassium, which support overall health. Regular consumption of red spinach is believed to improve blood circulation, boost immunity, prevent anemia, accelerate wound healing, and promote bone health due to its comprehensive nutritional content. This article aims to review the pharmacological activities of red spinach based on literature from credible sources such as Google Scholar, Garuda, Neliti, and Sinta, focusing on publications within the past five years. The review findings reveal that red spinach possesses various potential pharmacological properties. These include antioxidant activity, anemia treatment, reduction of liver enzymes such as SGOT and SGPT, improvement of liver function, and enhancement of metabolic processes. Additionally, red spinach is recognized for its benefits in maintaining facial skin health, suggesting its potential as a natural ingredient in skincare products. Therefore, red spinach is not only a nutritious vegetable but also holds promise as a natural herbal remedy with therapeutic potential for the future.
PEMANFAATAN POTENSI ALAMI SEBAGAI ANTIOKSIDAN Happy, Terza Aflika; Septiani, Linda; Graharti, Risti; Andrifianie, Femmy
Medula Vol 15 No 3 (2025): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v15i3.1825

Abstract

Indonesia is one of the world’s most biodiverse countries and possesses a vast potential of medicinal plants as natural therapeutic resources. Many medicinal plants traditionally used by local communities are known to contain secondary metabolites with antioxidant properties. Antioxidants play an essential role in preventing oxidative stress associated with degenerative and infectious diseases. This article aims to review the potential of secondary metabolite compounds from Indonesian medicinal plants as antioxidant agents based on previous studies. This study was conducted using a literature review method by analyzing relevant national and international scientific publications. The results indicate that various medicinal plants, including sweet potato leaves, green tea, roselle, celery, and Peperomia pellucida, contain polyphenolic compounds such as flavonoids, tannins, and phenols, as well as other secondary metabolites including alkaloids, saponins, terpenoids, quinones, coumarins, and anthocyanins. These compounds exhibit antioxidant activity through free radical scavenging, hydrogen atom donation, and inhibition of lipid peroxidation processes. In conclusion, Indonesian medicinal plants demonstrate significant potential as natural sources of antioxidants and offer promising prospects for further development in pharmaceutical and health applications, particularly as raw materials for phytopharmaceutical products and supportive therapies.
Efektivitas Beberapa Ekstrak Tanaman sebagai Ovisida terhadap Aedes aegypti dalam Pencegahan Demam Berdarah Dengue Septiani, Linda; aflika happy, terza; Graharti, Risti; Andrifianie, Femmy; Setyaningrum, Endah
Medula Vol 15 No 4 (2025): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v15i4.1827

Abstract

Dengue Hemorrhagic Fever (DHF) remains a major public health concern, with Aedes aegypti serving as the primary vector. The continuous use of synthetic insecticides has led to resistance development and environmental concerns, highlighting the need for safer and sustainable alternatives. This review aims to evaluate the ovicidal potential of selected plant extracts against Aedes aegypti as an early-stage vector control strategy. A literature review was conducted using relevant national and international publications focusing on plant-based ovicides. The findings indicate that extracts from Piper nigrum L., Ocimum basilicum, Syzygium myrtifolium Walp., Tithonia diversifolia, Acorus calamus L., Solanum lycopersicum, and Euphorbia hirta L. effectively reduce egg hatchability of Aedes aegypti. The ovicidal activity is associated with secondary metabolites such as flavonoids, alkaloids, saponins, tannins, terpenoids, polyphenols, and essential oils, which disrupt egg membranes and inhibit embryonic development in a concentration-dependent manner. These findings suggest that plant extracts possess promising potential as natural ovicides and may serve as a basis for further pharmaceutical development and formulation in sustainable dengue vector control.
Co-Authors Abda Abda aflika happy, terza Afriyani, Afriyani Ali, Nur Fitriana Muhammad Amanda, Fadyla Anggraeni, Ranesya Eka Ari Wahyuni Athallah, Muhammad Muzhaffar Ayu Larasati, Nikken Ciptaningrum, Sekar Rahmasari Ratna Daffa, Meysha Nur Damayanti, Ervina Daulay, Suryani Endah Setyaningrum, Endah Ety Apriliana Firdayanti, Ratri Mawas Happy, Terza Aflika Hasyimi, Meifia Helmi Ismunandar Idris, Mohamad Ihsanti Dwi Rahayu Intan Kusumaningtyas Junando, Mirza Lusina, Septia Eva Mallarangeng, Andi Nafisah Tendri Adjeng Marcellia, Selvi Morfi, Chicy Widya Muhammad Iqbal Mulya, Ireniza Pradevi Mutiara Hati, Nadia Oktoba, Zulpakor Pardilawati, Citra Yuliyanda Primasari Pertiwi Ramadhani, Untia Kartika Sari Ramdini, Dwi Aulia Rani Himayani Rasmi Zakiah Oktarlina Risti Graharti Rosa, Emantis Satria, Dzakiyyah Shoofina Jasmine Sayoeti, Muhammad Fitra Wardana Septiani, Linda Sofyan Musyabiq Wijaya Suryadi Islami Syafiz, Kamadie Sumanda T. Adjeng, Andi Nafisah Triyandi, Ramadhan Virginia, Jesica Wardhana S, Muhammad Fitra Wardhani, Oktiva Risma Widianto, Ardi Widodo, Alya Rahmah Winnugroho Wiratman, Manfaluthy Hakim, Tiara Aninditha, Aru W. Sudoyo, Joedo Prihartono Yuningrum, Hest