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Journal : Medula

SUPLEMENTASI EKSTRAK DAUN KELOR (Moringa oleifera L.) TERHADAP ANEMIA DEFISIENSI BESI: ARTIKEL REVIEW Satria, Dzakiyyah Shoofina Jasmine; Triyandi, Ramadhan; Iqbal, Muhammad; Andrifianie, Femmy
Medula Vol 14 No 2 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i2.929

Abstract

Iron is an important component of hemoglobin. The function of iron, which is as a source of energy for muscles so that it can affect physical endurance and the ability to work in adolescents. Iron deficiency can lead to hematological disorders of anemia. Anemia is a body condition in which the number of red blood cells and oxygen transport capacity is insufficient to meet the physiological needs of the body. Moringa leaves can be used as a substitute for iron tablets, because Moringa leaf powder contains 28 mg of iron. The method used in this writing, is literature review by collecting several research articles. This literature source search uses literature research sources in the form of google scholar and Pubmed. The inclusion criteria from the search, namely research articles using Indonesian and English, articles published within the last 10 years (2013-2023), and discussing the topic of moringa oleifera and anemia. The results of this literature search can be concluded that Moringa oleifera supplementation significantly increases serum iron levels.
Review Article: Pharmacological Activity of Robusta Coffee Plants (Coffee canephora) Virginia, Jesica; Iqbal, Muhammad; Triyandi, Ramadhan; Andrifianie, Femmy
Medula Vol 14 No 4 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i4.1054

Abstract

Coffee canephora or robusta coffee is a tree-shaped cultivated plant belonging to the Rubiaceae family and the Coffea genus. This plant is most widely planted in Indonesia, namely 91% more than Arabica coffee plantations and has great potential in its use as an alternative treatment for various diseases. Robusta coffee contains flavonoids, alkaloids, tannins, saponins and polyphenols. The two main polyphenolic compounds found in coffee are chlorogenic acid and caffeine, which each account for about 90% of all phenols found in coffee. This review article aims to determine the various pharmacological activities found in robusta coffee obtained from experimental studies conducted using electronic databases in the form of Google Scholar, Pubmed, and Mendley. The inclusion criteria in the article search were articles in Indonesian and English published in the last 10 years and the exclusion criteria were articles that could not be accessed in full. The results of the study of 25 articles show that the robusta coffee plant in the seeds, leaves and fruit skin has antibacterial, antioxidant, anticancer, anti-inflammatory, antifungal, antidiabetic, and biolarvicide pharmacological activities.
Penelusuran Potensi Antioksidan Dalam Beragam Ekstrak Daun Tanaman Obat Di Indonesia Mutiara Hati, Nadia; Triyandi, Ramadhan; Wardhana S, Muhammad Fitra; Andrifianie, Femmy; Iqbal, Muhammad
Medula Vol 14 No 5 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i5.1072

Abstract

Antioxidants are substances that are able to absorb or neutralize free molecules, preventing degenerative diseases such as heart disease and cancer by donating electrons to inhibit free radical chain reactions that damage the body. The use of natural medicines is increasingly becoming the main choice in Indonesian society. Even though various types of plants have been used for a long time, their use has not been optimal. In order to summarize and provide information regarding the potential of natural ingredients from various plant extracts which have antioxidant activity, a literature review was carried out. The method used was a database search via Google Scholar for the last 8 years (2015-2023), which produced 170 journals regarding plants with antioxidant activity. Of this number, 20 plants were selected based on the dark green leaves which have antioxidant activity by comparing the IC50 values ​​obtained. Plant extracts contain antioxidant compounds that can fight free radicals, offering a natural alternative to synthetic antioxidants.  Plants with high antioxidant activity often have characteristics such as phytochemical content such as flavonoids, polyphenols, carotenoids, and vitamin C, as well as bright colors such as purple, red, or orange which indicate the content of antioxidant pigments such as anthocyanins, lycopene, or beta-carotene. Apart from that, plants that have a bitter or astringent taste, such as green tea, red grapes, or blueberries, also tend to contain quite high levels of antioxidant compounds, coupled with their habit of growing in harsh or extreme environments and their traditional use in medicine or health supplements.
Review Article: Pharmacological Activities of Red Spinach (Amaranthus tricolor) Hasyimi, Meifia; Iqbal, Muhammad; Andrifianie, Femmy; Triyandi, Ramadhan
Medula Vol 15 No 2 (2025): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v15i2.1381

Abstract

  Red spinach (Amaranthus tricolor) is a leafy vegetable known for its distinctive red or purplish leaves. This plant is widely cultivated as its leaves are edible and packed with essential nutrients beneficial to the body. Red spinach is rich in antioxidants such as beta-carotene and vitamin C, along with vital minerals like iron, calcium, magnesium, phosphorus, and potassium, which support overall health. Regular consumption of red spinach is believed to improve blood circulation, boost immunity, prevent anemia, accelerate wound healing, and promote bone health due to its comprehensive nutritional content. This article aims to review the pharmacological activities of red spinach based on literature from credible sources such as Google Scholar, Garuda, Neliti, and Sinta, focusing on publications within the past five years. The review findings reveal that red spinach possesses various potential pharmacological properties. These include antioxidant activity, anemia treatment, reduction of liver enzymes such as SGOT and SGPT, improvement of liver function, and enhancement of metabolic processes. Additionally, red spinach is recognized for its benefits in maintaining facial skin health, suggesting its potential as a natural ingredient in skincare products. Therefore, red spinach is not only a nutritious vegetable but also holds promise as a natural herbal remedy with therapeutic potential for the future.