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Adverse Drug Reaction of Medroxyprogesterone Acetate Injectable Contraceptive on Acceptor Family Planning Programme Pardilawati, Citra Yuliyanda; Julaiha, Siti; Nurhayati, Nurhayati; Asriani, Meni
Jurnal Aisyah : Jurnal Ilmu Kesehatan Vol 7, No S1 (2022): Suplement 1
Publisher : Universitas Aisyah Pringsewu

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (599.811 KB) | DOI: 10.30604/jika.v7iS1.1297

Abstract

The government's family planning strategy for population balance is using contraception for couples of reproductive age. According to the 2018 Basic Health Research, the most common contraceptive is medroxyprogesterone acetate depot injection. The acceptor may experience complaints as a result of using these contraceptives. This study aims to determine the side effects of using depot medroxyprogesterone acetate injectable contraceptives on family planning acceptors in Jungai village, Rambang Kapak Tengah district, Prabumulih city in 2020. This study used a cross-sectional design, with data collected by interviews and a validated questionnaire. Purposive sampling was used to select 97 respondents who met the inclusion criteria. Univariate analysis was used to examine data from interviews. The percentage of adverse events experienced by acceptors of depot medroxyprogesterone acetate injectable contraceptive was 80% emotional changes, 75% menstrual disorders, 66% headaches, 66% weight changes, and 40% bone pain. Health professionals can use the findings of this study to provide counseling to family planning acceptors.  Abstrak: Salah satu program keluarga berencana yang dilakukan oleh pemerintah untuk menyeimbangkan jumlah penduduk adalah dengan penggunaan kontrasepsi pada pasangan usia subur. Berdasarkan Riset Kesehatan Dasar tahun 2018, diketahui bahwa penggunaan alat kontrasepsi terbanyak adalah suntik depot medroksiprogesteron asetat. Penggunaan alat kontrasepsi tersebut dapat menimbulkan keluhan dan efek samping bagi akseptor. Penelitian ini bertujuan untuk mengetahui efek samping dari penggunaan kontrasepsi suntik depot medroksiprogesteron asetat pada akseptor keluarga berencana di desa Jungai, Kecamatan Rambang Kapak Tengah, Kota Prabumulih Tahun 2020. Desain penelitian ini adalah cross sectional dengan pengumpulan data melalui wawancara menggunakan kuesioner yang tervalidasi. Pengambilan sampel secara purposive sampling terhadap 97 responden yang memenuhi kriteria inklusi. Data hasil wawancara dianalisis secara univariat. Hasil  penelitian  menunjukkan persentase  kejadian  efek samping yang dialami akseptor kontrasepsi suntik depot medroksiprogesteron asetat adalah perubahan emosi 80%, gangguan menstruasi 75%, sakit kepala 66%, perubahan berat badan 66% dan nyeri tulang 40%. Hasil penelitian ini dapat digunakan sebagai informasi bagi petugas kesehatan untuk memberikan konseling bagi akseptor keluarga berencana. 
Designing of Aplikasi Pendamping Diabetes (Si-PenDi) as a Control Tool for Type 2 Diabetes Mellitus Patients Julaiha, Siti; Sembiring, Elma Viorentina; Pardilawati, Citra Yuliyanda
Jurnal Kesehatan Vol 15 No 1 (2024): Jurnal Kesehatan
Publisher : Poltekkes Kemenkes Tanjung Karang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26630/jk.v15i1.4359

Abstract

Diabetes Mellitus is known as the mother of other diseases such as cardiovascular disease, kidney failure, and blindness. Indonesia ranks 5th in the world in terms of the number of Diabetes Mellitus sufferers in 2014. Non-compliance of patients with therapeutic recommendations can increase the risk of complications. Patient non-compliance is often caused by several factors, including forgetting to use medication, ADR, feeling healthy, and lack of education from health workers. The increasingly widespread use of Android-based applications among the public is an opportunity for patient consultations and reminding patients to be disciplined in using drugs so that they can improve patient clinical outcomes. Therefore, it is necessary to design an Aplikasi Pendamping Diabetes (Si-PenDi) as a control tool for type 2 diabetes mellitus patients undergoing therapy. This research aims to create the Aplikasi Pendamping Diabetes (Si-PenDi) as a tool to help control type 2 diabetes mellitus patients. The research is Research and Development research. The method is used to produce specific products and study the effectiveness of these products. This research reached TKT Level 2, making an Android-based technology application called the Si-PenDi (Diabetes Companion Application). The results obtained are that the Si-PenDi application has quite effective quality but cannot be said to be efficient and meet user satisfaction, so it is necessary to improve the design so that the application is better able to meet user expectations.
Analisis Peresepan Obat yang Berpotensi Tidak Tepat Berdasarkan Kriteria STOPP Pada Pasien Geriatri Salsabilla, Riefa Ayu; Pardilawati, Citra Yuliyanda; Iqbal, Muhammad; Oktarlina, Rasmi Zakiah
Medula Vol 14 No 2 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i2.952

Abstract

Potentially inappropriate prescribing (PIP) is a drug prescription without a proper clinical indication. The tools used to identify PIP in the geriatric patient is the STOPP criteria. The STOPP criteria evidently to improve treatment suitability, reduce medical costs, and reduce the occurrence of adverse drug reaction. The aim of this study is to evaluate the potentially inappropriate prescribing in geriatric patients using the STOPP criteria. This study is observational study used a cross-sectional approach. Geriatrics is an age group that is vulnerable to the side effects of drug use. Drug administration in geriatric patients is complex and requires a lot of consideration due changes in body composition and function, comorbidities, sensory and cognitive disorders, and polypharmacy, so that assistance with Potentially Inappropriate Medications (PIMs) and PPOs (Potentially Prescription Omissions) is important to improve the quality of treatment.
REVIEW ARTIKEL : UJI EFEK ANTI AGING DARI BERBAGAI EKSTRAK TUMBUHAN SECARA IN VIVO DAN IN VITRO Febriyanti, Triana; Sukohar, Asep; Pardilawati, Citra Yuliyanda; Adjeng, Andi Nafisah Tendri
Medula Vol 14 No 3 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i3.1041

Abstract

The outermost and largest organ in our body is the skin. Skin can experience aging when exposed to sunlight. Sunlight contains ultraviolet. Exposure to ultraviolet (UV) radiation causes damage to the skin and can lead to photoaging. Photoaging can be prevented with antioxidant compounds. Many plant extracts or synthetic compounds act as anti-aging agents. These plant extracts become active ingredients that can be formulated into pharmaceutical preparations. Plant extracts that have anti-aging potential include red cabbage, kepok banana peel, red pomegranate, moringa leaves, butterfly pea flower, black cumin seeds and libo fruit. To prove this, a test was carried out. The testing carried out can be in the form of in vivo and in vitro testing methods. This research was carried out using the article review method and obtained several journals from online literature, local journals and international journals, namely electronic searches with the keywords anti-aging, in vitro, in vivo on the website, namely Google Scholar. The number of journals used in this review was 11 journals spanning the last eight years. The results of the article review study showed that several methods used were UV-VIS spectrophotometer, DPPH method, anti-elastase, as well as tests on rats, mice and guinea pigs. From the results of the review of articles on plant extracts, most of them use in vivo tests on experimental animals.
Efektivitas Terapi Non-Farmakologi Pada Pasien Hipertensi Nadiya Widda Mawaddah; Damayanti, Ervina; Pardilawati, Citra Yuliyanda
Medula Vol 14 No 3 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i3.1056

Abstract

Hypertensive disease is the leading cause of early death worldwide. Hypertension is a common chronic medical condition characterized by sustained increases in arterial pressure. The high risk of side effects in the use of antihypertensive medicine for a long period of time causes non-pharmacological therapy of hypertension to be an alternative choice. This study aims to determine the effectiveness of non-pharmacological therapy in hypertensive patients in reducing and controlling normal blood pressure. The study used a literature review method with data sources of international scientific journals and articles using the PubMed database. The information search strategy used a combination of keywords such as "non-pharmacological therapy for hypertension" and "the effectiveness of non-pharmacological therapy in hypertension". Through the database search, 190 scientific articles and journals were obtained. A total of 12 scientific journals and articles were selected as reference sources for research that met the criteria. The results obtained from 12 journals and scientific articles showed that non-pharmacological therapy for hypertension was effective in reducing systolic and diastolic blood pressure. Non-pharmacological therapies recommended according to the reference sources are lifestyle modification, increasing physical activity such as aerobic exercise, intake of low sodium salt, acupuncture therapy, listening to music, relaxation therapy and increasing compliance with therapeutic interventions.
Kajian Polifarmasi Terhadap Keamanan Obat Pada Pasien Geriatri Jessy Dewi Awali; Pardilawati, Citra Yuliyanda; Soleha, Tri Umiana; Oktarlina, Rasmi Zakiah
Medula Vol 14 No 4 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i4.1059

Abstract

Geriatric patients an elderly patients suffering from a variety diseases (multimorbidity) caused by a decrease in body organ function. Multimorbidity in geriatric patients tends to lead to increased prescriptions and risks of polypharmacy. Polypharmacy can be defined as the use of five or more types of medications by a patient simultaneously. Polypharmacy is a major concern because of negative health impacts on patients, such as increased incidence of adverse drug reactions, harmful drug interactions, decreased medication adherence, and potentially inappropriate prescribing. Collaboration among doctors, pharmacists, other healthcare professionals, and families plays an important role in ensuring the effectiveness of treatment for geriatric patients, thus making the medications used safe and appropriate and reducing the negative impact of polypharmacy.
Kejadian Reaksi Obat yang Tidak Diinginkan Asidosis Tubulus Ginjal Pada Penggunaan Ibuprofen Sebagai Obat Over the Counter Alifah, Ghina Nur; Pardilawati, Citra Yuliyanda; Kurniawati, Evi; Sukohar, Asep
Medula Vol 14 No 4 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i4.1061

Abstract

Ibuprofen is an analgesic drug that can be obtained easily by patients because it is an over the counter (OTC) drug.  Ibuprofen when used can risk the lives of patients who consume it incorrectly.  Ibuprofen is a drug that causes damage to the kidneys or is nephrotoxic.  In large doses ibuprofen has been reported to cause hypokalemia, rhabdomyolysis and renal tubular acidosis Article searches with data sources from either journals or books with keywords used to facilitate searches. Journal articles used through case reports collect case reports of renal tubular acidosis due to the use of ibuprofen. In some of the case reports found, the use of ibuprofen had exceeded the dose set for OTC treatment. Patients with an average age of 41 years and reports ranged in age from 33 years to 63 years. Female patients has dominated the reported cases. The use of ibuprofen that caused the adverse drug reaction event belongs to type C, which is Chronic for continuous and long-term use of the drug. Non-pharmacological therapy that can be done is diet by limiting acid-producing foods and increasing alkaline-producing foods. Handling carried out on patients can be in the form of fluid resuscitation, electrolyte replacement through alkaline therapy, and supportive therapy according to the patient's clinical condition. Alkaline therapy using NaHCO3 and KHCO3 can be a fluid replacement and correct acidosis and hypokalemia.
Application of Non-Pharmacological Therapy in Patients with Depression Lathifah, Dina Silmi; Damayanti, Ervina; Oktarlina, Rasmi Zakiah; Pardilawati, Citra Yuliyanda
Medula Vol 14 No 5 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i5.1079

Abstract

Gejala-gejala gangguan depresi adalah kesedihan, kehilangan minat atau kesenangan, perasaan bersalah atau harga diri yang rendah, gangguan tidur atau nafsu makan, perasaan lelah, dan konsentrasi yang buruk, yang dapat berujung pada bunuh diri. Sebagian besar pasien depresi tidak merespons dengan baik terhadap antidepresan yang saat ini tersedia. Hampir 30% pasien depresi tidak mengalami remisi. Terapi non-farmakologi menjadi alternatif pilihan. Metode yang digunakan adalah literature review dan mengambil data yang bersumber dari Pubmed. Kata kunci yang digunakan, yaitu “Nonpharmalogical treatment of depression” dan didapatkan 191 artikel dan jurnal ilmiah. Sebanyak 7 artikel dan jurnal ilmiah terpilih menjadi sumber acuan. Hasilnya adalah terapi non-farmakologi yang dapat dilakukan, seperti akupuntur, latihan fisik (aerobik, yoga, dan meditasi), pengurangan tidur dan terapi cahaya, terapi kejang magnet, stimulasi intermiten theta-burst, dan stimulasi dalam magnetic transcranial, serta terapi ekspresi.
Pemberdayaan Kader Kesehatan Program TOSS TB Pada Masyarakat Wilayah Kerja Puskesmas Kedaton Kota Bandar Lampung Junando, Mirza; Oktarlina, Rasmi Zakiah; Ramdini, Dwi Aulia; Pardilawati, Citra Yuliyanda; Andrifianie, Femmy
Jurnal Pengabdian Kepada Masyarakat (JPKM) TABIKPUN Vol. 5 No. 2 (2024)
Publisher : Faculty of Mathematics and Natural Sciences - Universitas Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23960/jpkmt.v5i2.138

Abstract

Angka penemuan kasus TB di Lampung belum mencapai target nasional dan angka keberhasilan pengobatan masih rendah. Pada tahun 2018 Bandar Lampung menjadi kota tertinggi dalam penemuan kasus TB di Lampung, dengan wilayah terbanyak adalah Puskesmas Kedaton. TOSS TB merupakan program pemerintah dalam menanggulangi TB di Indonesia, mengajak masyarakat supaya memahami dengan benar penyakit TB dan penanggulangan sehingga diharapkan mampu membentuk masyarakat yang peduli TB. Terbentuknya  kader kesehatan yang terlatih dan meningkatkan pengetahuan dan keterampilan masyarakat tentang TB terutama pada penderita dan kontak sekitarnya. Pembentukan kader melalui pelatihan dan kunjungan rumah yang disertai pre test dan post test untuk mengukur tingkat pemahaman terkait TB. Masyarakat di wilayah kerja Puskesmas Kedaton sebanyak 46 orang kader yang dapat mengedukasi, skrining, memantau masyarakat, mendampingi penderita, dan melaporkan kasus  TB pada petugas kesehatan.
Uji Efektivitas Antioksidan Body Lotion Ekstrak Kulit Kopi Dan Biji Pepaya Sebagai Upaya Pemanfaatan Limbah Wardhani, Oktiva Risma; Daffa, Meysha Nur; Firdayanti, Ratri Mawas; Andrifianie, Femmy; Iqbal, Muhammad; Rahayu, Ihsanti Dwi; Pardilawati, Citra Yuliyanda
Sains Medisina Vol 3 No 3 (2025): Sains Medisina
Publisher : CV. Wadah Publikasi Cendekia

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Banyaknya hasil perkebunan kopi dan pepaya yang ada di Provinsi Lampung membuat banyaknya limbah yang dihasilkan seperti kulit kopi dan biji pepaya, namun hal ini belum dimanfaatkan secara optimal dan umumnya hanya dijadikan pupuk atau pakan ternak. Penelitian ini bertujuan untuk mengetahui efektivitas antioksidan dari body lotion yang diformulasi menggunakan ekstrak etanol kulit kopi dan biji pepaya sebagai upaya pemanfaatan limbah. Kulit kopi dan biji pepaya mengandung senyawa metabolit sekunder seperti polifenol yang berpotensi sebagai antioksidan. Metode penelitian yang digunakan adalah eksperimen laboratorium, dengan proses ekstraksi metode maserasi menggunakan pelarut etanol 70%. Skrining fitokimia menunjukkan adanya senyawa aktif seperti flavonoid, alkaloid, saponin, terpenoid dan tanin pada kedua ekstrak. Evaluasi terhadap body lotion yang dihasilkan meliputi uji organoleptik, uji homogenitas, uji pH, uji daya sebar, serta diuji aktivitas antioksidannya menggunakan metode DPPH (1,1-diphenyl-2-picrylhydrazyl). Hasil penelitian menunjukkan bahwa body lotion memiliki nilai IC50 sebesar 142,067 ppm, yang termasuk dalam kategori aktivitas antioksidan sedang. Penelitian ini menegaskan potensi pemanfaatan limbah kulit kopi dan biji pepaya dalam produk kosmetik yang tidak hanya bermanfaat bagi kesehatan kulit tetapi juga berkontribusi terhadap pengurangan limbah.