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All Journal Science and Technology Indonesia Jurnal Penelitian Pendidikan IPA (JPPIPA) Jurnal Abdi Insani Medfarm: Jurnal Farmasi dan Kesehatan Jurnal Mandala Pengabdian Masyarakat
Kasim, Athia Kurnia
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Physics Public Health Social Sciences

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Validated Chromatography Method for Analysis of Formaldehyde Migration Levels in Bottled Drinking Water Ramadhani, Nur; Yulianty, Risfah; Rifai, Yusnita; Aswad, Muhammad; Alam, Gemini; Naid, Tadjuddin; Kasim, Athia Kurnia
Science and Technology Indonesia Vol. 9 No. 3 (2024): July
Publisher : Research Center of Inorganic Materials and Coordination Complexes, FMIPA Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26554/sti.2024.9.3.660-668

Abstract

Polyethylene terephthalate (PET) is utilized in the containment of potable water, nonetheless, it is susceptible to impairment due to temperature and duration of storage. Migration of formaldehyde from PET arises as a consequence of thermal deterioration. This study aims to ascertain the extent of formaldehyde transference in PET-contained drinking water of varying condition, subjected to diverse temperature setting and storage durations. An examination into the levels of formaldehyde migration in polyethylene terephthalate (PET) bottled drinking water was effectively carried out employing a validated high-performance liquid chromatography (HPLC) technique. A total of 162 water samples from three different PET bottled water brands sourced from supermarkets in Palu City, Central Sulawesi, Indonesia, underwent analysis. The formaldehyde assessment was executed utilizing a mobile phase composition of methanol:acetonitrile:water (48:12:40 v/v) for 12.97 minutes at a flow rate of 0.8 mL/minute on the 1st day, the 14th day, and the 42nd day while stored at room temperature and exposed to sunlight. Formaldehyde, lacking effective chromophoric entities and not readily ionizable, necessitated derivatization with 2,4-dinitrophenylhydrazine before HPLC analysis. The findings of the study demonstrated exceptional method linearity within the concentration span of 0.5 to 1321 µg/mL, exhibiting a commendable correlation coefficient of 0.999. The limit of detection (LOD) and quantification (LOQ) were determined to be 17.33 and 57.76 µg/mL, correspondingly. Precision evaluations displayed average intraday and interday values of 128.46±3.48% and 103.19±0.12%, respectively (%RSD < 2/3 CV Horwitz ratio). The intraday and interday %recovery values were computed at 97.22±3.48% and 96.83±0.14% (n = 6). The scrutiny of formaldehyde concentrations in the water samples unveiled the absence of formaldehyde migration.
Increasing Parental Participation in Preventing Stunting in Toddlers in Powelua Village, Donggala Regency: Peningkatan Partisipasi Orang Tua dalam Pencegahan Stunting pada Balita di Desa Powelua Kabupaten Donggala Puspita Dewi, Niluh; Aril, Moh; Tedy, I Wayan; Wirawan, Wayan; Kasim, Athia Kurnia
Jurnal Mandala Pengabdian Masyarakat Vol. 5 No. 2 (2024): Jurnal Mandala Pengabdian Masyarakat
Publisher : Progran Studi Farmasi Universitas Mandala Waluya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35311/jmpm.v5i2.498

Abstract

Permasalahan prioritas saat ini yang dialami masyarakat Desa Powelua yaitu tingginya angka stunting dengan jumlah adalah 58 anak. Hal ini menjadi salah satu upaya yang dilakukan sebagai wujud Tri Dharma Perguruan Tinggi dalam meningkatkan partisipasi orang tua dalam pencegahan stunting pada anak balita, sehingga angka stunting dapat mengalami penurunan. Kegiatan PkM ini bekerjasama dengan aparat desa dan juga kelompok posyandu Desa Powelua, melalui beberapa pendekatan pemecahan masalah. Tujuan pelaksanaan pengabdiaan ini untuk memberikan pemahaman dan keterampilan kepada masyarakat Desa Powelua tentang partisipasi Masyarakat terutama orang tua dalam pencegahan stunting pada balita. Penyuluhan diberikan dengan metode ceramah interaktif melalui pembagian leaflet, buku pencegahan stunting dan bakti sosial. Efektifitas penyuluhan diuji dengan pemberian kuisioner kepuasan masyarakat terhadap kegiatan yang dilaksanakan. Evaluasi ketercapaian dilaksanakan dengan memberikan Pre-test dan Post-test kepada masyarakat khususnya para orang tua terhadap materi yang disampaikan dengan indikator keberhasilan menunjukkan terjadi peningkatan pengetahuan para orang tua sebesar 90% dengan kategori sangat baik. Dengan dilaksanakannya penyuluhan stunting dengan metode yang berbeda ini diharapkan dapat meningkatkan pengetahuan masyarakat mengenai apa itu stunting, penyebab stunting, bahaya stunting untuk jangka panjang serta cara menanggulangi dampak dari stunting sehingga dengan begitu dapat meminimalisir terjadinya stunting pada anak.
ANALISIS DAN PENERAPAN DAUN UNGU SEBAGAI ANTIOKSIDAN, ANALGETIK DAN ANTIINFLAMASI PADA MASYARAKAT DI KELURAHAN LAMBARA, KECAMATAN TAWAELI Dewi, Niluh Puspita; Toding, Ficanata A.; Kasim, Athia Kurnia; Liska, Iluh; Wirawan, Wayan
Jurnal Abdi Insani Vol 12 No 4 (2025): Jurnal Abdi Insani
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/abdiinsani.v12i4.2435

Abstract

Daun ungu (Graptophyllum pictum L. Griff) merupakan tanaman yang banyak dimanfaatkan sebagai obat tradisional oleh masyarakat, karena mengandung berbagai senyawa bioaktif seperti flavonoid, tanin, dan alkaloid. Penggunaan obat herbal kembali diminati masyarakat seiring tren "Back to Nature" terutama setelah adanya wabah pandemi COVID-19. Pemanfaatan daun ungu sebagai antioksidan, analgetik, dan antiinflamasi masih belum diketahui sepenuhnya oleh warga masyarakat Kelurahan Lambara, Kecamatan Tawaeli, sehingga diperlukan edukasi mengenai potensi pemanfaatannya dalam pengobatan. Tujuan pengabdian ini adalah untuk menganalisis kandungan pada daun ungu, menerapkan manfaat daun ungu bagi masyarakat, serta menghimpun data dan informasi dari berbagai sumber literatur sebagai rujukan bagi masyarakat mengenai berbagai manfaat daun ungu agar diketahui oleh masyarakat. Metode yang digunakan adalah persiapan dengan melakukan studi literatur, mengumpulkan dan menganalisis data dari beberapa tulisan yang membahas manfaat daun ungu yang ditinjau berdasarkan zat fitokimia dan aktivitas farmakologisnya serta memberikan informasi kepada masyarakat, dan pendampingan langsung kepada masyarakat. Pengabdian yang telah dilakukan menunjukkan peningkatan pengetahuan masyarakat sebesar 85% dengan kategori sangat baik. Kegiatan penyuluhan diikuti oleh 20 warga di Huntara Kelurahan Lambara melalui metode ceramah dan pembagian leaflet informasi. Pemeriksaan kesehatan gratis berupa pengecekan gula darah, kolesterol, dan asam urat telah diberikan kepada peserta, disertai konsultasi kesehatan dengan apoteker. Pemberian sembako juga dilaksanakan kepada 80 kepala keluarga di daerah tersebut sebagai bentuk dukungan sosial. Masyarakat menunjukkan antusiasme tinggi dalam memanfaatkan daun ungu sebagai alternatif pengobatan dan pewarna alami. Kegiatan pendampingan berhasil meningkatkan pengetahuan masyarakat tentang pemanfaatan daun ungu sebagai antioksidan, analgetik, dan antiinflamasi.
Self-Medication With Antibiotics By The People Of East Mamungaa Village Rikwan, RIKWAN; Kasim, Athia Kurnia; Suryadinata, A. Moh Whisnu; S.A Belike, Desy Safitri; Gunibala, Ciciliya
MEDFARM: Jurnal Farmasi dan Kesehatan Vol 14 No 2 (2025): Medfarm: Jurnal Farmasi dan Kesehatan
Publisher : LPPM Akafarma Sunan Giri Ponorogo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.48191/medfarm.v14i2.597

Abstract

The unsupervised use of antibiotics continues to be a pressing public health issue because it may contribute to antimicrobial resistance and increase the likelihood of unwanted health effects. A community’s understanding of when and how antibiotics should be used is one factor that can influence self-medication practices. For this reason, research sought for eva;uatng level knowledge related to independent antibiotic use among residents of East Mamungaa Village. A quantitative descriptive observational approach was selected as it enables a clear depiction of knowledge patterns within the population. A total of 172 individuals 18–65 years asked by purposive sampling, and information was obtained using a structured questionnaire assessing knowledge of indications, safety considerations, and appropriate antibiotic use. The results indicate that 60.5% of participants possessed a moderate level of knowledge, 28.5% demonstrated a good level of knowledge, and 11.0% showed limited knowledge. These outcomes reveal that although most respondents have a basic awareness of antibiotics, important gaps remain—especially in recognizing the dangers of using these medications without clinical guidance. Accordingly, continuous community-based education efforts are needed to strengthen proper antibiotic practices and minimize the risks associated with self-medication.
Effect of Purple Leaf (Graptophyllum pictum (L.) Griff) Emulsion on the Histological Parameters of Streptozotocin-Induced Diabetic Rats Dewi, Niluh Puspita; Dewik, Komang; Alaydrus, Syafika; Kasim, Athia Kurnia; Polontalo, Nani Astria; Wirawan, Wayan; Andini, Dian; Irma, Irma; Fatu, Imelda Synthia
Jurnal Penelitian Pendidikan IPA Vol 12 No 1 (2026)
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v12i1.14172

Abstract

Damage to vital organs such as the liver, kidneys, and pancreas is a common complication of diabetes mellitus, characterized by chronic hyperglycemia due to pancreatic cell dysfunction. Graptophyllum pictum (purple leaf) is a potential herbal therapy containing bioactive compounds with antioxidant and organ-protective effects. This study aimed to evaluate the effect of purple leaf emulsion on blood glucose levels and the histopathological features of diabetic rats induced by streptozotocin. Rats were divided into six groups: normal control, negative control, positive control (glibenclamide), and three doses of purple leaf emulsion (100, 200, and 300 mg/kg BW). After 28 days of treatment, the emulsion significantly reduced blood glucose levels and improved the histological structures of the liver, kidneys, and pancreas. The 200 mg/kg BW dose was most effective for pancreatic protection, while 300 mg/kg BW provided optimal hepatoprotective and renoprotective effects. These findings highlight the potential of purple leaf as a natural antidiabetic and organ-protective agent.
Co-Authors Alaydrus, Syafika Andini, Dian Aril, Moh Dewik, Komang Fatu, Imelda Synthia Gemini Alam Gunibala, Ciciliya Irma Irma Liska, Iluh Muhammad Aswad Niluh Puspita Dewi, Niluh Puspita Polontalo, Nani Astria Puspita Dewi, Niluh Ramadhani, Nur Rikwan, Rikwan Risfah Yulianty S.A Belike, Desy Safitri Suryadinata, A. Moh Whisnu Tadjuddin Naid Tedy, I Wayan Toding, Ficanata A. wirawan, Wayan Yusnita Rifai, Yusnita