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All Journal Journal of Food and Pharmaceutical Science Pharma Xplore : Jurnal Sains dan Ilmu Farmasi Journal of Pharmaceutical and Health Research Al-MIKRAJ: Jurnal studi Islam dan Humaniora International Journal of Public Health Excellence (IJPHE) Journal of Food and Pharmaceutical Sciences Jurnal Pengabdian Masyarakat Ilmu Kesehatan
Tanjung, Siti Aisyah
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Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences

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Edukasi Pembuatan Lip Balm Menggunakan Sari Kulit Buah Melon Orange (Cucumis Melo Var. Cantalupo) Tanjung, Siti Aisyah; Fatimah, Cut; Gunawan, Muhammad; Ningsih, Afni Sari
Jurnal Pengabdian Masyarakat Ilmu Kesehatan Vol 6, No 1 (2025): Edisi Januari
Publisher : LPPM Institut Kesehatan Helvetia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33085/jpmik.v6i1.6384

Abstract

Bibir merupakan salah satu bagian wajah yang mempengaruhi persepsi estetis wajah. Oleh karena itu, penting sekali untuk menjaga kesehatan dan tampilan bibir. Lip balm merupakan sediaan yang biasa digunakan untuk bibir yang berguna sebagai pelembab, melindungi bibir dari pengaruh lingkungan, dan mencegah penguapan pada sel-sel epitel mukosa bibir. Lip balm biasanya terdiri dari basis transparan seperti lilin, lanolin, setil alkohol, maupun petrolatum yang berfungsi sebagai pelembab. Selain pelembab, lip balm juga memerlukan tambahan antioksidan untuk melindungi bibir dari radikal bebas serta anti UV agar melindungi bibir dari sinar matahari. Kegiatan pengabdian masyarakat ini bertujuan untuk memberikan edukasi kepada masyarakat mengenai pembuatan lip balm menggunakan sari kulit buah melon orange (Cucumis melo var. cantalupo). Metode yang digunakan pada kegiatan pengabdian masyarakat ini adalah edukasi dalam bentuk peragaan disertai dengan ceramah dan umpan balik dari masyarakat. Melalui kegiatan pengabdian masyarakat ini, maka diperoleh kesimpulan bahwa: (1) Masyarakat mendapatkan pengetahuan baru mengenai pemanfaatan bahan-bahan alami untuk pembuatan lip balm; (2) Warna lip balm kulit melon yang disukai masyarakat adalah warna lip balm dengan konsentrasi kulit melon 10% dan 20%. Dari segi aroma, masyarakat menyukai lip balm kulit melon dengan konsentrasi kulit melon 20%. Dari segi bentuk, masyarakat menyukai lip balm kulit melon dengan konsentrasi kulit melon 10% dan 20%.
Antihypercholesterolemia Effectiveness Test of Ceremai Leaf Ethanol Extract (Phyllanthus Acidus (L.) Skeels) on Male White Rats (Rattus Norvegicus) Gunawan, Muhammad; Tanjung, Siti Aisyah; Fitriani, Enny; Safriana, Safriana
International Journal of Public Health Excellence (IJPHE) Vol. 4 No. 2 (2025): January-May
Publisher : PT Inovasi Pratama Internasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55299/ijphe.v4i2.1356

Abstract

Cholesterol is an increase in blood fat levels that can cause various heart diseases. Ceremai is one of the plants that some Indonesian people use to treat high blood pressure, diabetes mellitus and high cholesterol levels. This study aims to determine the effectiveness of ethanol extract of ceremai leaves in reducing blood cholesterol levels in male white mice with hypercholesterolemia. The inducers given to the test animals were 4 ml of quail egg yolk and propylthiouracil mixed with drinking water ad libitum. This study is an experimental study using 20 mice and divided into 5 groups. Group I (solvent control) CMC 0.5%, group II (comparison), group III, group IV and V (treatment) ethanol extract of ceremai leaves at a dose of 0.15, a dose of 0.3 and 0.6 g / KgBW. The extract was administered orally to the mice, and their cholesterol levels were measured on the 7th and 14th days after treatment. Cholesterol levels of each group were analyzed statistically using the One Way ANOVA method and Duncan's Post-Hoc test using SPSS 24.0. The results of statistical tests on blood cholesterol levels between simvastatin groups, ethanol extract of ceremai leaves showed a significant difference with an α value> 0.05. From the results of the study, it can be concluded that the ethanol extract of ceremai leaves has the activity of reducing blood cholesterol levels in male white rats induced by quail egg yolk and propylthiouracil with an effective EEDC dose of 0.3 g / kgBB.
Diuretic Effectiveness Test of Leucare Leucabeth (Leucaena leucocephala (Lam.) de Wit) Ethanol Extract on Male White Rats (Rattus norvegicus) Muhammad Gunawan; Tanjung, Siti Aisyah; Fitriani, Enny
International Journal of Public Health Excellence (IJPHE) Vol. 5 No. 1 (2025): June-December
Publisher : PT Inovasi Pratama Internasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55299/ijphe.v5i1.1535

Abstract

Leucaena leucaena seeds are widely believed to be a plant that can treat various ailments, including diuretics. Leucaena seeds contain a high amount of alkaloids, saponins, flavonoids, tannins, protein, fat, calcium, phosphorus, iron, amino acids, and leucanol. The purpose of this study was to determine whether ethanol extract of leucaena seeds can have a diuretic effect on male white rats. This study used 30 male white rats divided into five groups: Group I (solvent control) with 1% CMC. Group II (comparison) with furosemide. Groups III, IV, and V (treatment) were given ethanol extract of leucaena seeds at doses of 150 mg/kg BW, 300 mg/kg BW, and 600 mg/kg BW, respectively. The test preparations were administered orally using a metabolic cage equipped with a rat urine collector. Observations were made every hour for 8 hours to determine total urine volume. The urine volume of each group was statistically analyzed using ANOVA and the LSD test. The results of the statistical test of urine volume between the furosemide and ethanol extract groups of lamtoro seeds (Leucaena leucocephala (Lam.) de Wit) showed no significant difference. From the results of the study, it can be concluded that the higher the concentration of EEBL suspension given, the more urine volume will be produced, and when the EEBL suspension was given at a dose of 600 mg/kg BW, the results were almost comparable to the group of animals given furosemide suspension.
Antidiabetic Effectiveness Test of Ethanol Extract of Brown Leaves (Theobroma Cacao L.) Against Mice (Mus Musculus) Gunawan, Muhammad; Safriana; Tanjung, Siti Aisyah; Andilala
International Journal of Public Health Excellence (IJPHE) Vol. 3 No. 2 (2024): January-May
Publisher : PT Inovasi Pratama Internasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55299/ijphe.v3i2.775

Abstract

Diabetes mellitus is a group of metabolic diseases characterized by hyperglycemia that occurs due to abnormalities in insulin secretion, insulin action or both. DM sufferers are increasing from year to year, accompanied by increasing costs of therapy, therefore, as an alternative to controlling blood glucose levels, use natural ingredients such as cocoa leaves. The aim of this research was to determine the effectiveness of ethanol extract of cocoa leaves (Theobroma cacao L.) in reducing blood glucose levels in mice that had been induced by Aloxan. The research method used was experimental research. The research stages were sample collection, sample identification, making simpilicia, examining the characteristics of simpilicia, making extracts using maceration using 96% ethanol solvent, and testing the antidiabetic effect of EEDC in mice induced by alloxan at a dose of 175 mg/kg. bb intraperitoneally. Diabetic mice were divided into 5 groups, each group consisting of 5 mice that were given the test material 50 mg/KgBB of ethanol extract of brown leaves; 100 mg/KgBB; and 200 mg/KgBB, Metformin 65 mg/KgBB, and CMC 0.5%. Next, blood glucose levels were measured on days 3, 6, 9, 12, and 15, the percentage reduction in blood glucose levels was calculated, then the data was analyzed using the One-Way ANOVA method and Duncan's test, to see real differences between treatments. The research results showed that simplicia, the ethanol extract of brown leaves contains flavonoids, alkaloids, tannins, steroids/triterpenoids, saponins and glycosides. Cocoa leaf ethanol extract has effectiveness in lowering glucose levels, at the 5th and 6th hours it shows good effectiveness at a dose of 200 mg/KgBW of (72.16 ± 0.1.51)% and (82.80 ± 0.73 )%, not significantly different from metfromin 65 mg/KgBB of (74.45 ± 1.51)% and (83.29 ± 1.01).
Testing the Antihyperurisemic Effectiveness of the Ethanol Extract of Henna Leaf (Lawsonia Mermis L.) on Induced Male Mice (Mus Musculus) with Chicken Liver and Potassium Bromate Muhammad Gunawan; Tanjung, Siti Aisyah; Safriana, Safriana; Fitriani, Enny
International Journal of Public Health Excellence (IJPHE) Vol. 4 No. 1 (2024): June-December
Publisher : PT Inovasi Pratama Internasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55299/ijphe.v4i1.1126

Abstract

Hyperuricemia is a condition that is marked by an increase in blood pressure in the blood that exceeds the normal level, ie above 7.0 mg/dl in the patient and above 6.0 mg/dl in women. It is generally intended to address hyperuricemia in the use of synthesized drugs that can give rise to the effect of retinal pain, vomiting, diarrhea, damage to the liver, nephritis in the brain and hypertheritivity. By therefore developing alternative treatments using plant medicine as well as parsley nails (Lawson mermis L.). This research is aimed at identifying extracurricular nephew nails (EEDPK) against decreasing levels of pregnancy in males who are induced by liver cancer and galleria. This research uses experimental methods with gathering and processing materials, identification of growth, making implicit, making extracts, determining water levels, preparing animal trials, and testing EEDPK effects. Animals used 24 eggs were divided into 6 groups of tests, group divisions included normal groups, induction, comparison, and EEDPK in 3 doses of 150 mg/kg body weight, 300 mg/kg body weight, and EEDPK 600 mg/kg body weight version 25 with 95% confidence level. The results of the EEDPK water level assessment were 3.33%. The results of the efficacy of hyperuricides will be shown that EEDPK provides the effect of the most effective extracts as antihyperuricemia is 300 mg/kgBB compared to other groups of extract.
Formulasi Hair Tonic Ekstrak Etanol Kulit Buah Pepaya (Carica Papaya L.) dan Uji Efektivitas Pertumbuhan Rambut pada Marmut Jantan (Cavia porcellus) Candani, Mella; Gunawan, Muhammad; Tanjung, Siti Aisyah; Bagas, Muhammad
AL-MIKRAJ Jurnal Studi Islam dan Humaniora Vol. 5 No. 01 (2024): Al-Mikraj, Jurnal Studi Islam dan Humaniora
Publisher : Pascasarjana Institut Agama Islam Sunan Giri Ponorogo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37680/almikraj.v5i01.6198

Abstract

Hair for humans has an important role, in addition to protecting the skin from adverse environments, hair also plays an important role in a person's appearance. Losing a lot of hair due to hair loss can cause a lack of self-confidence, disappointment, and frustration, so it must be addressed immediately so as not to worsen the condition that can cause baldness. This study aims to determine whether there is a content of secondary metabolite compounds in fresh herbal medicine, herbal medicine powder and ethanol extract of papaya fruit skin; ethanol extract of papaya fruit skin (Carica papaya L.) can be formulated in the form of hair tonic preparations; whether the difference in concentration of ethanol extract of papaya fruit skin (Carica papaya L.) provides different activities in triggering hair growth in guinea pigs. This research method uses a quantitative approach and is experimental with independent variables, namely papaya fruit skin, herbal medicine, and ethanol extract of papaya fruit skin with concentrations of 10%, 20%, 30%. Research stages: phytochemical screening of fresh papaya fruit peel, powdered simplicia and ethanol extract, hair tonic formulation containing ethanol extract of papaya fruit peel 10%, 20% and 30%, hair tonic evaluation includes: organoleptic, viscosity, stability, pH, irritation, and preference test. And hair growth activity test on male guinea pigs. The results showed that the ethanol extract of papaya fruit peel contains alkaloids, flavonoids, saponins, steroids, and glycosides, can be formulated into hair tonic (EEKP) that meets physical quality requirements. Hair tonic EEKP 30% is the best because it has high hair growth activity, which is an average of 16.375 mm where this EEKP 30% hair tonic has almost the same hair growth activity as the positive control, which is an average of 16.782 mm.
Formulasi Sediaan Krim Ekstrak Etanol Kulit Buah Sawo (Manilkara Zapota L.) dan Uji Efektivitas Sebagai Pelembab Kulit: Formulation of Ethanol Extract Cream Preparation of Sapodilla Fruit Peel (Manilkara Zapota L.) and Effectiveness Test as Skin Moisturizer Hamna, Aulia; Safriana, Safriana; Fatimah, Cut; Tanjung, Siti Aisyah
AL-MIKRAJ Jurnal Studi Islam dan Humaniora Vol. 5 No. 01 (2024): Al-Mikraj, Jurnal Studi Islam dan Humaniora
Publisher : Pascasarjana Institut Agama Islam Sunan Giri Ponorogo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37680/almikraj.v5i01.6444

Abstract

The skin is the largest organ of the body that is often exposed to the environment so it is prone to dryness and health problems. Skin moisturizing cosmetic preparations often contain synthetic chemicals so that their use often causes side effects, in the form of skin disorders so that it is necessary to find alternative natural ingredients that can provide safer skin moisture, for example ripe sapodilla fruit skin, which has been empirically proven to moisturize the skin. This study aims to test the chemical content, formulate ethanol extract of ripe sapodilla fruit skin in the form of a cream, and evaluate the effectiveness and safety of the cream as a skin moisturizer. The method used in this study is an experimental method with a quantitative approach, starting with the manufacture of simplicia and its characteristics test, manufacture of ethanol extract of ripe sapodilla fruit skin, phytochemical screening test, making cream preparations with ethanol extract concentrations of ripe sapodilla fruit skin 5%, 10%, and 15% followed by physical quality tests including organoleptic and stability tests, homogeneity tests, emulsion type tests, pH tests, spreadability tests, adhesion tests, irritation tests on volunteers, preference tests, and effectiveness tests of the preparation as a skin moisturizer. The results of the study showed that phytochemical screening of fresh ripe sapodilla fruit skin, crude drugs, and its ethanol extract showed the presence of alkaloids, flavonoids, tannins, saponins, steroids/triterpenoids, and glycosides. Ethanol extract of ripe sapodilla fruit skin can be formulated into a skin moisturizer cream preparation with stable color, aroma, and shape within 4 weeks, the pH of the preparation is in accordance with the skin pH of 4.5-6.5, does not irritate and has effectiveness as a skin moisturizer, increases water content in the skin by 40.04 ± 3.47%. and reduces oil content by 24.46 ± 2.20%.
Formulasi Sediaan Masker Gel Ekstrak Etanol dari Daun Kembang Sepatu (Hibiscus Rosa-Sinensis L.) Sebagai Pelembab Kulit: Formulation of Ethanol Extract Gel Mask Preparation from Hibiscus Leaves (Hibiscus Rosa-Sinensis L.) as a Skin Moisturizer Sari, Secillia May; Tanjung, Siti Aisyah; Gunawan, Muhammad; Safriana, Safriana
AL-MIKRAJ Jurnal Studi Islam dan Humaniora Vol. 5 No. 01 (2024): Al-Mikraj, Jurnal Studi Islam dan Humaniora
Publisher : Pascasarjana Institut Agama Islam Sunan Giri Ponorogo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37680/almikraj.v5i01.6503

Abstract

Skin often dries out due to evaporation and loss of moisture due to dry air, hot weather, aging, skin diseases, etc., so that the skin surface becomes scaly and wrinkled. Moisturizers consist of ingredients that can form and change the texture of dry and rough skin and reduce water evaporation from the skin. The purpose of this study was to analyze the formulation of a gel mask preparation of ethanol extract from hibiscus leaves (Hibiscus Rosa-Sinensis L.) as a skin moisturizer. This study was conducted using an experimental method using hibiscus leaves (Hibiscus rosa-sinensis L.) as a test material obtained by maceration using 80% ethanol solvent which had previously been tested for phytochemical screening and characterization of simplicia. The stages of this study include: making hibiscus leaf extract, making gel mask preparations, organoleptic tests, homogeneity tests, stability tests, viscosity tests, pH tests, spreadability tests, drying time tests, irritation tests, preference tests and skin moisturizer effectiveness tests. Phytochemical screening results showed that hibiscus leaves contain alkaloids, flavonoids, tannins, saponins, steroids and glycosides. Preparations with concentrations of 5%, 10%, 15% produced a homogeneous and stable gel mask from the first day to the 4th week, the pH of the preparation ranged from 6.30-6.56, the viscosity test produced 4.116-5.067, the spreadability test 6.2-6.7 cm, the dry time preparation test 20-22 minutes, the irritation test on volunteers showed no irritation and itching, the preference test value produced by the panelists liked the preparation from a concentration of 15% in terms of color, aroma and shape, and the effectiveness test as a skin moisturizer for water content taken from the highest concentration of 15% obtained an average result of 32.97 ± 2.93%, and for a decrease in oil content obtained 36.71 ± 6.89%.
Uji Aktivitas Antibakteri Sediaan Gel Ekstrak Etanol Daun Rimbang (Solanum Torvum Swartz) terhadap Bakteri Propionibacterium Acnes: Antibacterial Activity Test of Ethanol Extract Gel Preparation of Rimbang Leaves (Solanum Torvum Swartz) against Propionibacterium Acnes Bacteria Nurjannah, Sofia; Kusumastuti, Melati Yulia; Safriana, Safriana; Tanjung, Siti Aisyah
AL-MIKRAJ Jurnal Studi Islam dan Humaniora Vol. 5 No. 2 (2025): Al-Mikraj, Jurnal Studi Islam dan Humaniora
Publisher : Pascasarjana Institut Agama Islam Sunan Giri Ponorogo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37680/almikraj.v5i2.6849

Abstract

The skin is the outermost part of the body that limits it from the human environment. Damage to the skin glands can cause skin disorders, one of which is acne. The bacteria that cause acne are Propionibacterium acnes bacteria. Antibiotics are needed to inhibit bacterial growth, but improper use can cause side effects. The purpose of this study was to explore the antibacterial activity of the ethanol extract gel preparation of rimbang leaves (solanum torvum swartz) against propionibacterium acnes bacteria. This research method is with an experimental quantitative approach. The stages of the study include screening of powdered simplicia and ethanol extract, Formulation of gel preparations without test materials and ethanol extract of rimbang leaves (EEDR) 10%, 20%, 30%, Evaluation tests of the preparations include: organoleptic, homogeneity, stability, adhesion, spreadability, viscosity, pH, irritation, and preference. Then the antibacterial activity test uses the well method. The results showed that the screening results on powdered simplicia and ethanol extract met the physical quality requirements of secondary metabolite compounds. The results of the antibacterial activity of EEDR 30% bacterial inhibition diameter of 14.33 ± 8.72. EEDR 20% produced a bacterial inhibition diameter of 12 ± 11.4. EEDR 10% produced a bacterial inhibition diameter of 10.67 ± 8.70. While the blank produced a bacterial inhibition diameter of 6.33 ± 3.26. From this study it can be concluded that the preparation of ethanol extract gel of rimbang leaves has inhibitory activity against Propionibacterium acnes bacteria.
Co-Authors Andilala Aulia, Syafitri Ayi, Alicia Bagas F, Muhammad Bagas, Muhammad Candani, Mella Dewi Safitri Fatimah, Cut Fitriani, Enny Hamna, Aulia Kusumastuti, Melati Yulia Kusumastuti, Yulia Muhammad Gunawan Muhammad Gunawan Ningsih, Afni Sari Nurjannah, Sofia Safriana Safriana Safriana Sari, Secillia May