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All Journal Biotika: Jurnal Ilmiah Biologi CommIT (Communication & Information Technology) JURNAL PERBENIHAN TANAMAN HUTAN Jurnal Matematika Sains dan Teknologi Chimica et Natura Acta ALCHEMY Jurnal Penelitian Kimia Journal of Science Innovare Komputasi: Jurnal Ilmiah Ilmu Komputer dan Matematika FITOFARMAKA: Jurnal Ilmiah Farmasi EKOLOGIA : Jurnal Ilmiah Ilmu Dasar dan Lingkungan Hidup Jurnal Ilmu Kefarmasian Indonesia Jurnal Sosial dan Teknologi Gunung Djati Conference Series
Triastinurmiatiningsih, Triastinurmiatiningsih
Program Studi Biologi, FMIPA Universitas Pakuan, Bogor
Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Control & Systems Engineering Decision Sciences, Operations Research & Management Earth & Planetary Sciences Economics, Econometrics & Finance Education Energy Engineering Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Library & Information Science Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Public Health Other

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UJI AKTIVITAS EKSTRAK Sargassum crassifolium SEBAGAI ANTIFUNGI Candida albicans - Triastinurmiatiningsih; Rina Yulianti; Dewi Sugiharti
Ekologia: Jurnal Ilmiah Ilmu Dasar dan Lingkungan Hidup Vol 15, No 1 (2015): Ekologia : Jurnal Ilmiah Ilmu Dasar dan Lingkungan Hidup
Publisher : Universitas Pakuan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33751/ekol.v15i1.207

Abstract

Sargassum crassifolium is a species that is included in the class Phaeophyceae.  This Brown algae is a alginat source manufacturer and contain active compounds include flavonoids, saponins and triterpenoid which function as antibacterial, antiviral and antifungal  properties. The purpose of this research is to know the activities of Sargassum crassifolium in inhibiting the growth of Candida albicans and phytochemicals content. The extraction is done using the method of maceration. Test the effectiveness of antifungal performed using diffusion agar method and paper discs. The parameters observed were drag area width. Data was analyzed using Anova with a level of confidence of 95%. The results showed that the average diameter of the drag area extract Sargassum crassifolium is most effective on a 75% concentration of 21.6 mm. Phytochemical analysis shows that Sargassum crassifolium contains the active compounds such as flavonoids, saponins, and triterpenoid. Key words  : Sargassum crassifolium, Candida albicans, antifungal
The Diversity of Macroalgae Species with Prospects for Medicinal Applications in Aquatic Environments Shobir, Haris; Triastinurmiatiningsih, Triastinurmiatiningsih; Ismanto, Ismanto
Journal of Science Innovare Vol 8, No 1 (2025): Journal of Science Innovare, Volume 08 Number 02 2025
Publisher : Universitas Pakuan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33751/jsi.v8i1.12819

Abstract

Macroalgae are important marine organisms known to contain polysaccharides such as alginate, agar, and carrageenan, as well as bioactive compounds and pigments with significant pharmaceutical potential. This study aimed to identify and analyze the diversity of macroalgae species that have potential medicinal properties in the coastal waters of Cidatu Beach, Pandeglang Regency, Banten Province, Indonesia. The research employed a transect method with three sampling stations along the intertidal zone. At each station, three transects were established 5 meters apart, and each transect contained five 1×1 m plots separated by 5 meters. A total of 12 macroalgae species were identified, comprising three species of Chlorophyceae (Ulva intestinalis, Ulva reticulata, Chaetomorpha crassa), five species of Phaeophyceae (Padina australis, Turbinaria conoides, Turbinaria decurrens, Sargassum polycystum, Sargassum crassifolium), and four species of Rhodophyceae (Gracilaria salicornia, Gracilaria coronopifolia, Gelidium sp., Amphiroa fragilissima). The Shannon–Wiener diversity index (H′) of 2.169 indicates a moderate level of species diversity in the study area. Environmental conditions such as temperature (29–30°C), salinity (31–32‰), and pH (7.0) were within the optimal range for macroalgal growth, although light intensity was relatively low (1,939 lux). Based on literature analysis, ten of the recorded species demonstrated potential pharmacological value, exhibiting antibacterial, antifungal, antiviral, antitumor, antihypertensive, and antihemorrhagic properties. Among these, species of Sargassum, Padina, and Gracilaria are particularly noteworthy for their bioactive compounds, including tannins, flavonoids, and polysaccharides. The moderate diversity and high medicinal potential of the identified macroalgae suggest that Cidatu Beach supports a rich yet underutilized marine biota. Further biochemical and pharmacological investigations are recommended to explore their potential as sustainable sources of natural medicinal compounds.
In vitro antimicrobial screening of Manihot esculenta Sao Pedro Petro Extract and Identification of Active Compounds Widiastuti, Diana; Sinaga, Siska Elisahbet; Sofian, Yayan; Mulyati, Ade Heri; Warnasih, Siti; Sadjarwa, Boedi; Dhiandani, Sri Boedi; Herlina, Eka; Triastinurmiatiningsih, Triastinurmiatiningsih; Agustine, Dine
Chimica et Natura Acta Vol 12, No 1 (2024)
Publisher : Departemen Kimia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/cna.v12.n1.50154

Abstract

Sao Pedro Petro cassava tubers (Manihot esculenta Ctro) are one of the cassava varieties, generally cultivated in tropical and subtropical areas. This plant has the potential to contain antimicrobial bioactive compounds. This research aimed to demonstrate the antibacterial activity of each fraction and subsequently identify the specific active fraction for in-depth analysis of its bioactive compounds. The evaluation of antimicrobial activity and the identification of bioactive compounds were conducted using the well-diffusion method and UPLC-QTOF MS (Ultra Performance Liquid Chromatography-Quadrupole Time of Flight Mass Spectrometry). Results indicated that the ethanol, n-hexane, and n-butanol fractions exhibited no inhibitory effects on the tested microorganisms. In contrast, the ethyl acetate fraction displayed the highest level of antimicrobial activity (Staphylococcus aureus ATCC 6538, Pseudomonas aeruginosa ATCC 27853, and Candida albicans ATCC 1023). Further analysis of the ethyl acetate fraction revealed key bioactive compounds, including Coixol (phenol-group), Trigonelline and 2,6-Dimethyl quinoline (alkaloid-group), and Chebuloside-II (terpenoid-group). In summary, this pioneering research represents the first-ever exploration of the antimicrobial potential of cassava tubers, specifically focusing on the Sao Pedro Petro variety. The study not only underscores the antimicrobial properties of Manihot esculenta tubers but also identifies specific bioactive compounds within them, providing valuable insights into their potential therapeutic applications
Efektivitas Media Sosial dalam Pengembangan Kampung Wisata Jamu Harsani, Prihastuti; Jayawinangun,, Roni; Triastinurmiatiningsih, Triastinurmiatiningsih; Ardiansyah , Deden
Jurnal Sosial Teknologi Vol. 3 No. 3 (2023): Jurnal Sosial dan Teknologi
Publisher : CV. Green Publisher Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59188/jurnalsostech.v3i3.659

Abstract

Kegiatan Pengabdian Kepada Masyarakat ini bertujuan untuk meningkatkan pemberdayaan ibu-ibu PKK dan komunitas Kepemudaan di Desa Ciburuy, Kecamatan Cigombong, Kabupaten Bogor melalui peningkatan pengetahuan dan keterampilan mengenai pelatihan budidaya tanaman obat, pembuatan simplisia, herbal dan promosi produk menggunakan media sosial. Kegiatan ini dilatarbelakangi oleh kurangnya pemberdayaan ekonomi masyarakat pedesaan dibandingkan dengan masyarakat perkotaan. Metode pelaksanaan kegiatan pengabdian masyarakat ini adalah dengan memberikan pelatihan dan praktik budidaya tanaman obat, pembuatan simplisia, jamu dan promosi produk menggunakan media sosial. Implikasi dari kegiatan pengabdian masyarakat ini adalah untuk meningkatkan pengetahuan dan kemampuan masyarakat PKK dan Karang Taruna dalam memproduksi tanaman obat dan memasarkan produk berupa simplisia dan jamu bagi generasi milenial sehingga memiliki daya saing dan memperkuat pilar ekonomi dalam mencapai tujuan pembangunan ekonomi yang berkelanjutan.
Optimasi Metode Microwave-Assisted Extraction (MAE) untuk Menentukan Kadar Flavonoid Total Alga Coklat Padina australis Bina Lohita Sari; Triastinurmiatiningsih Triastinurmiatiningsih; Tri Saptari Haryani
ALCHEMY Jurnal Penelitian Kimia Vol 16, No 1 (2020): March
Publisher : UNIVERSITAS SEBELAS MARET (UNS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/alchemy.16.1.34186.38-49

Abstract

Metode Microwave-Assisted Extraction (MAE) digunakan untuk mengekstraksi senyawa flavonoid dari simplisia alga coklat Padina australis. Sampel diperoleh dari Pantai Bayah, Banten Indonesia. Kondisi optimal ekstraksi ditentukan dengan Response Surface Methodology (RSM). Desain Box-Behnken (BBD) digunakan untuk mengevaluasi pengaruh 3 faktor dengan 3 level yaitu daya microwave (300, 450, 600 watt), konsentrasi etanol  (30, 50, 70%), dan waktu ekstraksi (7, 8 dan 9 menit) dengan 15 perlakuan yang berbeda. Hasil disain eksperimen dengan BBD menunjukkan kondisi ekstraksi optimum yaitu pada daya microwave 414 watt, konsentrasi etanol 50,33% dan waktu ekstraksi 7,89 menit menghasilkan kadar prediksi flavonoid sebesar nilai 0,2963%. Nilai ini mendekati nilai kadar flavonoid yang diperoleh secara eksperimental sebesar 0,2961%, pada kondisi menggunakan daya microwave sebesar 450 watt, konsentrasi etanol 50% dengan lama ekstraksi 8 menit. Berdasarkan hasil penelitian, kadar flavonoid total dapat meningkat secara signifikan dengan melakukan optimasi proses MAE menggunakan RSM.Optimization of Microwave-Assisted Extraction for Total Flavonoid Content of Padina australis Brown Algae.  Microwave-Assisted Extraction (MAE) was done to extraction flavonoid from Padina australis brown algae simplicial. The sample collected from Bayah coastal waters, Banten Indonesia. Optimum extraction condition was determined by the response surface methodology (RSM). The Box-Behnken design (BBD) was used to evaluate the influence of 3 factors with 3 levels extraction that is microwave power (300, 450, 600 watts), ethanol concentration (30, 50, 70%), and extraction time (7, 8 and 9 minutes) with 15 different runs. The research showed that optimum extraction condition was at 414 watts of microwave power, 50.33% ethanol concentration, and time extraction of 7.89 minutes yielded a predicted value of total flavonoid content of 0.2963%. This value approaches to the flavonoid content obtained experimentally at 0.2961% under condition of 450 watts microwave power, 50% ethanol concentration, and time extraction of 8 minutes. Based on the result, total flavonoid content can be significantly increased by optimizing the MAE process use RSM.
Co-Authors - Ertina - Ismanto Ade Heri Mulyati, Ade Heri Ade Kusmiati Agustine, Dine Alexander A. S. Gunawan, Alexander A. S. Alexander Agung Santoso Gunawan Ardiani, Weni Ardiansyah , Deden Arfa Ul Hikmah Arie Qur’ania Bilkis, F.G Bina Lohita Sari Bina Lohita Sari D.G. Maelani Dede Giwang Maelani Dewi Sugiharti Dhiandani, Sri Boedi Diana Widiastuti E. Mulyati Effendi Eha Soliha Eka Herlina Erika Candra Ertina, - F.G Bilkis Ghina Athyah Wahid Haris Shobir Hikmah, Arfa Ul Ihat Ismawat Indah Nur Sayyidah Ismanto Ismanto Ismanto, - Jureka Tampubolon Lili Ayu Wulandhari Maelani, D.G. MOERFIAH . Moerfiah Moerfiah Nazar Muhamad Ikhbal Prihastuti Harsani Rahayu, S.Y. Srie Rangga Eka S. P Ratna Uli Damayanti Sianturi Rina Yulianti Rina Yulianti Roni Jayawinangun S.Y. Srie Rahayu Sadjarwa, Boedi Shobir, Haris Sinaga, Siska Elisahbet Siti Warnasih Sofian, Yayan Soliha, Eha Sri Wiedarti Sri Wiedarti Sugiharti, Dewi Tampubolon, Jureka Tania Oktavia Herlinda Tri Saptari Haryani Tri Saptari Haryani Tri Saptari Haryani Weni Ardiani Wulandhari, Lili Ayu Yulianita Yulianita Zulkhoir Zulkhoir