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All Journal Qanun Medika - Medical Journal Faculty of Medicine Muhammadiyah Surabaya Jurnal Ilmiah Permas: Jurnal Ilmiah STIKES Kendal Proceeding ISETH (International Summit on Science, Technology, and Humanity) Jurnal Pengabdian Masyarakat Medika Biomedika
Puspitasari, Metana
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Biochemistry, Genetics & Molecular Biology Computer Science & IT Education Engineering Health Professions Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary Other

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Blood Parameters and Length of Hospitalization in Pediatric Dengue Virus Infection Patients Salsabiela, Salwa; Puspitasari, Metana; Jatmiko, Safari Wahyu
Proceeding ISETH (International Summit on Science, Technology, and Humanity) 2024: Proceeding ISETH (International Summit on Science, Technology, and Humanity)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/iseth.5539

Abstract

This research aims to evaluate the correlation between erythrocyte level, hematocrit, hemoglobin, and Hb/RDW ratio with the length of hospitalization in pediatric patients with DVI. This observational study used a cross-sectional design and analyzed secondary data from 41 pediatric DVI patients at PKU Muhammadiyah Sampangan Surakarta Hospital. The correlation between hematological parameters and length of hospitalization was analyzed using the Spearman test. Laboratory results showed a mean erythrocyte count of 5.05 million cells/nL (SD 0.61), a median hematocrit of 39.5%, hemoglobin of 13.6 g/dL, and Hb/RDW ratio of 1.03. Bivariate correlation test showed erythrocyte level (r = 0.027, p = 0.867), hematocrit (r = -0.004, p = 0.983), hemoglobin (r = 0.079, p = 0.625), and Hb/RDW ratio (r = 0.116, p = 0.472) showed no significant association with length of hospitalization. This study provides insights into the relationship between hematological parameters and the length of hospital stay in pediatric dengue patients. While no significant correlation was found, it highlights the complexity of factors influencing outcomes and the need to explore other prognostic markers. Conducted in an Indonesian endemic region, the research contributes to understanding DVI management and underscores the importance of a comprehensive, multifactorial approach to improving patient care strategies.
Aggregate Index of Systemic Inflammation is Correlated with Plasma Leakage Indicator in Dengue Virus Infection Jatmiko, Safari; Puspitasari, Metana; Aisyah, Riandini
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 9 No 02 (2025): Qanun Medika Vol 09 No 02 July 2025
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v9i02.25847

Abstract

Severe dengue virus infection (DVI) is characterized by thrombocytopenia and plasma leakage (PL) due to the release of vasoactive cytokines by immune cells such as monocytes, lymphocytes, neutrophils, and platelets in response to dengue virus (DENV). This immune response triggers systemic inflammation, altering monocyte, lymphocyte, and neutrophil kinetics, which in turn affects leukocyte differentials. PL is indicated by an increase in hematocrit (Hct). This study aims to evaluate the potential use of the Aggregate Index of Systemic Inflammation (AISI) as an indicator of plasma leakage. A correlative analytical study with a cross-sectional approach was conducted on 70 pediatric DVI patients diagnosed according to the 2009 WHO criteria and confirmed by anti-DENV IgM/IgG tests. Patients with a history of malignancy, autoimmune thrombocytopenic purpura, or secondary DVI were excluded. Absolute neutrophil, monocyte, platelet, and lymphocyte counts, AISI, and Hct levels were obtained from complete blood count results using a hematology analyzer. The results showed that AISI and lymphocytes correlated with Hct, with correlation values of (r=0.410, p<0.001) and (r=0.446, p<0.001), respectively. In contrast, monocytes, neutrophils, and platelets did not correlate with Hct, with correlation values of (r=-0.009, p=0.942), (r=-0.059, p=0.628), and (r=-0.175, p=0.147), respectively. In conclusion, AISI levels in DVI were low and negatively correlated with Hct, a known indicator of PL. These findings suggest that AISI has potential as a marker for PL and disease severity in DVI.
EFEKTIVITAS PENYULUHAN KESEHATAN TERHADAP PEMAHAMAN PENYAKIT DIABETES MELITUS DAN FAKTOR RISIKONYA Puspitasari, Metana; Rahmah, Sandawi Rianda; Marchelina, Sherly
Jurnal Pengabdian Masyarakat Medika Vol 5. No. 2, September 2025
Publisher : Universitas Muhamamdiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/jpmmedika.v5i2.5866

Abstract

ABSTRAK Diabetes melitus adalah kondisi medis yang mengakibatkan peningkatan kadar gula darah akibat gangguan fungsi atau produksi insulin. Berdasarkan klasifikasi Perkeni tahun 2021, terdapat empat tipe diabetes, yaitu tipe 1, tipe 2, gestasional, dan tipe lain yang disebabkan oleh faktor spesifik. Menurut hasil SKI 2023 menunjukkan peningkatan prevalensi Diabetes Melitus tipe 2 di Indonesia meningkat menjadi 11,7% pada tahun 2023, naik dari 10,9% pada tahun 2018 pada kelompok usia ≥15 tahun. Pendekatan menyeluruh dan holistik diperlukan untuk mengelola Diabetes Melitus, melibatkan tindakan yang bersifat promotif, preventif, kuratif, dan rehabilitatif. Penyuluhan ini bertujuan untuk meningkatkan pemahaman masyarakat mengenai penyakit diabetes, sebagai langkah promotif dan preventif dalam mengatasi Diabetes Melitus. Studi ini menggunakan metode one group pre-test post-test dengan melibatkan 40 peserta dari Kelurahan Sigran, Kecamatan Geneng, Kabupaten Sukoharjo. Analisis data dilakukan dengan Wilcoxon test. Temuan dari penelitian menunjukkan adanya peningkatan skor dari rata-rata 67 pada pretest menjadi 85,25 pada posttest. Berdasarkan hasil ini dan nilai p < 0,05, dapat disimpulkan bahwa penyuluhan kesehatan telah berhasil meningkatkan pengetahuan peserta tentang diabetes melitus.   ABSTRACT Diabetes melitus is a medical condition that results in elevated blood sugar levels due to issues in insulin function or production. According to Perkeni's 2021 classification, there are four types of diabetes: Type 1, Type 2, gestational, and other types caused by specific factors. The 2023 Health Survey (SKI) indicated an increase in the prevalence of Type 2 Diabetes Melitus in Indonesia, rising to 11.7% in 2023 from 10.9% in 2018 in the age group of 15 years and older. A comprehensive and holistic approach is essential for managing Diabetes Melitus, involving promotive, preventive, curative, and rehabilitative measures. This community service activity aims to enhance public awareness and knowledge about diabetes as a preventive and promotive measure against the disease. This study applied a one-group pre-test post-test design approach. Forty participants from Sigran community in Geneng District, Sukoharjo Regency participated. Data was analyzed using the Wilcoxon test. Results showed that the average score at the pretest stage was 67, while the post-test average score was 85.25. The analysis indicates that health education significantly improved community knowledge about diabetes melitus, as evidenced by a p-value < 0.05.
Co-Authors Agustina, Dinda Dwi Alfajri, Asri Alim, Fika Nurul Ardhana, Regita Faqihudin, Fadli Rizal Fikri, Elfin Ainul Fithriyah, Saidatul Hartia, Nabila Putri Iwan Setiawan Jamiko, Safari Wahyu Jatmiko, Safari Jatmitko, Safari Wahtu Kencana, Nabila Safhira Titan kusumaningsih, dwi Listiana Masyita Dewi Marchelina, Sherly Nida Faradisa Fauziyah Pambudi, Nasrurrofiq Risvana Bayu Paramadina, Izzati Rahmah, Sandawi Rianda Retno Sintowati - Riandini Aisyah Safari Wahyu Jatmiko Salsabiela, Salwa Sulistyani Sulistyani Sulistyani, S Yamsun, Rahmat Dani Yulistina, Desita Yunitama, Alifa Agil Dhillu