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All Journal Proceeding ISETH (International Summit on Science, Technology, and Humanity) Prosiding University Research Colloquium
Sulistyani, S
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Phenytoin Topical as Pain Neuropathic Therapy: A Scoping Review Sulistyani, S; Rosyidah, Devi Usdiana; Rahmawati, Nailena Widya; Nugrahaen, Sarwasri Fajra; Goprani, Lidya; Sulistiyo, Azka Hafiy; Prameswari, Elza; Hutami, Norma Putri; Azwar, Muhammad Thoriq; Amalia, Riza
Proceeding ISETH (International Summit on Science, Technology, and Humanity) 2024: Proceeding ISETH (International Summit on Science, Technology, and Humanity)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/iseth.5500

Abstract

Background: Neuropathic pain is a type of pain that can cause prolonged pain in patients. Oral treatment takes a long time and can cause side effects, which can further reduce patient compliance with therapy. Topical treatment is a more acceptable alternative because it has minimal systemic side effects. Phenytoin is an anticonvulsant drug that can be used as a therapy for neuropathic pain. The side effects of oral phenytoin are minimized by using topical preparations. Objective: To obtain information on the effectiveness of topical phenytoin in neuropathic pain. Long-term goal, conduct clinical trials in patients and make topical phenytoin preparations in collaboration with one of the PBF (Large Pharmaceutical Companies) in Indonesia. Methods: Three electronic databases were searched on January 13, 2022: Google Scholar. PubMed and ScienceDirect. All relevant literature was included after screening according to the PRISMA statement. Data obtained were synthesized based on PICO (population, interventions, comparisons, and outcomes). Results: This paper examines case reports, case series, and pre-existing research articles in which topical phenytoin significantly reduces neuropathic pain. Conclusion: Topical phenytoin may be an alternative in the selection of neuropathic pain therapy due to its minimal side effects compared to oral therapy. However, further studies need to be conducted to compare with other topical anticonvulsants.
Relationship between Neutrophil to Lymphocyte Ratio (NLR) and Lymphocyte to Monocyte Ratio (LMR) with Severity of Ischemic Stroke Paramadina, Izzati; Kusumaningsih, Dwi; Sulistyani, S; Puspitasari, Metana
Proceeding ISETH (International Summit on Science, Technology, and Humanity) 2024: Proceeding ISETH (International Summit on Science, Technology, and Humanity)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/iseth.5516

Abstract

Purpose: The purpose of this study was to determine the correlation between Neutrophil to Lymphocyte Ratio (NLR) and Lymphocyte to Monocyte Ratio (LMR) with the severity of ischemic stroke. Methodology: According to the criteria, a cross-sectional sample of ischemic stroke patients at Yarsis Islamic Hospital in Surakarta (January 2023–November 2024) participated in this observational analytical study, which used the National Institutes of Health Stroke Scale (NIHSS) as a severity measure. Results: 44 subjects were obtained with an equal ratio of gender and hypertension was the most common comorbidity. A substantial relationship between the NLR with the NIHSS score (p value = 0.001) and between LMR with the NIHSS score (p value < 0.001) was discovered using bivariate analysis. NLR (OR 4.713; p = 0.044) and LMR (OR 10.780; p = 0.043) had a 42.2% (R square = 0.422) impact on the severity of ischemic stroke, according to the findings of the logistic regression test. Applications: Based on this study, there is a significant relationship between NLR and LMR with the severity of ischemic stroke. As a consequence, NLR and LMR test findings may serve as a substitute indicator of acute ischemic stroke patients' severity.
Correlation between Glasgow Coma Scale (GCS) Score and Lesion Location with Mortality in Patients with Ischemic Stroke Pramesti, Neva Galih; Sulistyani, S; Busyra, B; Risanti, Erika Diana
Proceeding ISETH (International Summit on Science, Technology, and Humanity) 2024: Proceeding ISETH (International Summit on Science, Technology, and Humanity)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/iseth.5526

Abstract

Purpose: This study evaluated the correlation between GCS scores and lesion locations with mortality in ischemic stroke patients. Methodology: This cross-sectional study analyzed secondary data from 50 ischemic stroke inpatients at RSUD dr. Soeratno Gemolong between August 2022 and August 2024. GCS scores were categorized as severe (≤8), moderate (9–12), and mild (13–15). Lesion locations were classified as supratentorial or infratentorial. The relationship between these variables and mortality was analyzed using the chi-square test. Results: A significant correlation was found between GCS scores and mortality (p = 0.001). Patients with severe GCS scores had a 54% mortality rate compared to 8% in patients with mild scores. No significant association was observed between lesion location and mortality (p = 0.118), although patients with supratentorial lesions showed a higher mortality rate (40%) than those with infratentorial lesions (28%). Applications/Originality/Value: GCS scores are a strong predictor of mortality in ischemic stroke patients, highlighting their importance in early risk stratification. Lesion location, while showing trends, was not significantly associated with mortality. The findings support healthcare policy improvements, personalized care, and future research into comprehensive stroke management. Further research is needed to explore these factors comprehensively and improve patient outcomes.
The Relationship between Leukocytosis and Hyponatremia with Mortality Ischemic Stroke Patients Futana, Ninda Pradani; Sulistyani, S; Setiawan, Iwan; Djatmiko, Safari Wahyu
Proceeding ISETH (International Summit on Science, Technology, and Humanity) 2024: Proceeding ISETH (International Summit on Science, Technology, and Humanity)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/iseth.5527

Abstract

Background: Ischemic stroke is the cause of increased mortality in the world, especially in developing countries. Ischemic stroke is caused by a decrease in blood flow and oxygen supply in the brain. Increased leukocyte count as an inflammatory response, as well as impaired sodium levels in the form of hyponatremia, can worsen the patients condition and increase the risk of death. Leukocytosis after ischemia causes inflammation of neurons and continuous brain injury. Leukocyte infiltration can also increase obstruction causing oxygen levels to decrease. Hyponatremia which associated with cerebral salt wasting (CSWS), Syndrome of inappropriate antidiuretic hormone (SIADH), cerebral edema and increased intracranial pressure also increases the risk of death for ischemic stroke patients. Purpose: The purpose of this study is determine the relationship between leukocytosis and hyponatremia with the morality of ischemic stroke patients. Methodology: The method used in this study is a cross sectional. Sampling was carried out using non-randomized sampling and obtained 61 patients with a diagnosis of ischemic stroke and recorded completely in medical reports from 2022 to 2024 at RSUD dr soeratno Gemolong. Statistical analysis used was chi square for bivariate and logistic regression for multivariate. Results: The results obtained a significant p value in leukocytosis of 0.007 and hyponatremia of 0.008. The results of multivariate analysis obtained significant values in both variables with p< 0.05. Applications: In this research that shows an association between leukocytosis and hyponatremia with ischemic stroke mortality can be used further for researchers and clinicians, especially in the health fields.
Vertigo as A Manifestation of Cervical Rib: Case Report Sulistyani, S; Hutami, Norma Putri; Sulistiyo, Azka Hafiy; Prameswari, Elza; Azwar, Muhammad Thoriq; Setiawan, Iwan
Proceeding ISETH (International Summit on Science, Technology, and Humanity) 2024: Proceeding ISETH (International Summit on Science, Technology, and Humanity)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/iseth.5528

Abstract

Background: A cervical rib is a congenital anomaly of a cervical spine vertebra, occurring in about 0.5% to 1% of the population. It is most commonly associated with the seventh cervical vertebra. Cervical ribs can lead to localized pain and affect surrounding structures, presenting with a variety of clinical symptoms. Objective: To demonstrate that a cervical rib can cause vertigo, particularly central vertigo. Case: A 55-year-old woman experienced vertigo and nausea for approximately ten years. Physical examination revealed her head tilted to the left, with an inability to maintain a straight position. Positive cerebellar signs were observed. Imaging studies showed a cervical rib on the seventh cervical vertebra in the X-ray and bilateral cerebellar infarctions in a CT scan. Discussion: The patient, a female, had a cervical rib on the right side. The vertigo was linked to a cerebellar stroke caused by the cervical rib. The underlying mechanism likely involved compression of the subclavian artery and poor posture. Conclusion: Vertigo can be a clinical manifestation of cerebellar stroke, resulting from subclavian artery compression due to a cervical rib.
The Relationship Mean Arterial Pressure and Sleep Quality with The Incident of Tension Type Headache Susanto, Syarafina Ayu Putri; Setiawan, Iwan; Sulistyani, S; Herawati, Erna
Proceeding ISETH (International Summit on Science, Technology, and Humanity) 2024: Proceeding ISETH (International Summit on Science, Technology, and Humanity)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/iseth.5542

Abstract

Background: Headache is one of the most prevalent neurological illnesses seen in emergency departments. Tension Type Headache (TTH) is the most prevalent type of headache, affecting up to 70% of people aged 18 to 65 globally. Risk factor of TTH often discussed include poor sleep quality and vascular control. According to studies, poor sleep quality increases the frequency and intensity of headaches, including TTH. Furthermore, vascular control, particularly Mean Arterial Pressure (MAP), is thought to be associated with TTH. Previous research suggests that high blood pressure may diminish the occurrence of TTH via a mechanism known as hypertension-induced hypoalgesia, while evidence on the link between MAP and TTH are sparse. Purpose: This study aims to evaluate the relationship between mean arterial pressure, sleep quality, and the occurrence of tension-type headache. Methodology: The study was conducted in Surakarta Boarding High School using a cross-sectional design. The sample approach used was simple random sampling. The data was examined using univariate and bivariate statistics. The chi-square and Fisher's exact tests were used to do bivariate analysis. Results: The bivariate analysis revealed that the p-value for the association between mean arterial pressure and the incidence of TTH is 0.694, and the p-value for the relationship between sleep quality and the occurrence of TTH is 0.992. Applications: The study's findings show that Mean Arterial Pressure and sleep quality had no relationship with the incidence of Tension Type Headache. Thus, further research is needed to explore this risk factor more deeply, enabling clinicians to educate about this risk factors.
Korelasi Event Related Potential-Frekuensi Denyut Jantung pada Event Takbir, Sepertiga Bagian Pertama, Tengah dan Akhir dari Sholat pada Pria Dewasa Muda Sehat Romadhon, Yusuf Alam; Sulistyani, S
Prosiding University Research Colloquium Proceeding of The 10th University Research Colloquium 2019: Bidang MIPA dan Kesehatan
Publisher : Konsorsium Lembaga Penelitian dan Pengabdian kepada Masyarakat Perguruan Tinggi Muhammadiyah 'Aisyiyah (PTMA) Koordinator Wilayah Jawa Tengah - DIY

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Abstract

Latar belakang: Penelitian sebelumnya mendapatkan kesimpulan bahwa aktivitas sholat dapat menurunkan denyut jantung sebagai penanda keadaan rileks. Belum pernah dikaji korelasi antara aktivitas kognitif sholat dengan berbagai segmen aktivitas sholat dengan variasi denyut jantung. Tujuan: Untuk mendapatkan gambaran tingkat korelasi aktivitas kognitif sholat dengan variasi denyut jantung antar berbagai segmen aktivitas sholat. Metode: Penelitian ini melibatkan 14 orang pria muda sehat memeragakan aktivitas sholat dalam keadaan duduk dan mata terpejam. Diukur dengan metoda EEG kuantitatif dan EKG pada lead I pada momen waktu takbir, sepertiga bagian pertama, tengah, dan akhir. Hasil: Didapatkan korelasi yang secara statistik bermakna pada momen takbir yakni r = -0.616 dan nilai p = 0.019 serta resultan nilai ERP dan HR di semua momen dengan nilai r = -0.401 dan p = 0.002 Kesimpulan: secara umum aktivitas sholat membuat keadaan menjadi rileks dan korelasi signifikan secara statistik berada di momen takbir.
Pengaruh Urutan Kelahiran dan Gender Terhadap Tingkat Kecemasan Pada Remaja Puspitasari, Nadya Dwi; Romadhon, Yusuf Alam; Ichsan, Burhannudin; Sulistyani, S
Prosiding University Research Colloquium Proceeding of The 13th University Research Colloquium 2021: Kesehatan dan MIPA
Publisher : Konsorsium Lembaga Penelitian dan Pengabdian kepada Masyarakat Perguruan Tinggi Muhammadiyah 'Aisyiyah (PTMA) Koordinator Wilayah Jawa Tengah - DIY

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Abstract

Gangguan jiwa yang dialami oleh penduduk Indonesia salah satunya yaitu gangguan kecemasan. Gangguan kecemasan mulai terjadi sejak usia remaja (15-24 tahun), dengan prevalensi 6,2%. Berdasarkan survei yang dilakukan pada tahun 2020 melalui website resmi oleh Perhimpunan Dokter Spesialis Kedokteran Jiwa Indonesia (PDSKJI) sebanyak 1.552 responden didapatkan 63% responden mengalami cemas. Responden paling banyak adalah perempuan 76,1% dengan usia minimal 14 tahun. Remaja perempuan menunjukkan lebih banyak tekanan psikologis, kecemasan dan depresi dibandingkan anak laki-laki. Selain perbedaan gender pada anak remaja, pola asuh keluarga berdasarkan urutan kelahiran juga dapat menyebakan tingkat kecemasan. Metode: Penelitian ini merupakan penelitian observasional analitik dengan pendekatan cross sectional. Subjek penelitian adalah remaja yang tinggal dibeberapa wilayah di Indonesia, yang terjangkau dalam jejaring sosial secara online dengan memenuhi kriteria restriksi dan dilaksanakan mulai November sampai dengan Desember 2020. Teknik pengambilan sampel dengan purposive sampling. Instrumen yang digunakan adalah data identitas responden, kuesioner skala L-MMPI, angket penelitian, dan kuesioner DASS-21. Data yang terkumpul akan diolah dan dianalisis menggunakan uji chi square. Hasil: Hasil uji chi square untuk urutan kelahiran didapatkan nilai p = 0,022 dan OR= 2,105 sedangkan hasil untuk gender didapatkan nilai p= 0,397 dan OR=0,702. Hasil uji regresi logistik didapatkan nilai p untuk urutan kelahiran p= 0,017 dan nilai p untuk gender p= 0,373. Nilai R2 sebesar 0,46%. Kesimpulan: Hasil dari penelitian ini dapat disimpulkan bahwa terdapat pengaruh urutan kelahiran terhadap tingkat kecemasan dan tidak ada pengaruh yang bermakna antara gender terhadap tingkat kecemasan.
HUBUNGAN KECEMASAN DAN MOTIVASI BELAJAR DENGAN PRESTASI BELAJAR MAHASISWA FK UMS MASA PANDEMI COVID-19 Andyani, Nanda Arum; Herawati, Erna; Sulistyani, S; Agustina, Tri
Prosiding University Research Colloquium Proceeding of The 13th University Research Colloquium 2021: Kesehatan dan MIPA
Publisher : Konsorsium Lembaga Penelitian dan Pengabdian kepada Masyarakat Perguruan Tinggi Muhammadiyah 'Aisyiyah (PTMA) Koordinator Wilayah Jawa Tengah - DIY

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Awal tahun 2020, dunia digemparkan dengan merebaknya virus baru yaitu corona virus jenis baru (SARS-CoV-2). Kementerian Pendidikan dan Kebudayaan Pemerintah Republik Indonesia telah melarang perguruan tinggi maupun sekolah untuk melaksanakan pembelajaran tatap muka (konvensional). Salah satu dampak akibat sistem pembelajaran daring dimasa pandemi ini adalah kecemasan pada mahasiswa, yang bisa menyebabkan terjadinya penurunan prestasi. Semakin tinggi kecemasan, maka semakin rendah motivasi belajar dan sebaliknya semakin rendah kecemasan maka semakin tinggi motivasi belajar. Untuk mengetahui hubungan tingkat kecemasan dan motivasi belajar dengan tingkat prestasi belajar mahasiswa fakultas kedokteran UMS. Penelitian ini menggunakan desain penelitian cross sectional dan dilakukan pada bulan Desember 2020 di Fakultas Kedokteran Universitas Muhammadiyah Surakarta. Besar subjek penelitian adalah 61 responden yang diambil dengan teknik purposive sampling. Pengambilan data tingkat kecemasan menggunakan kuesioner DASS-42, pengambilan data motivasi belajar menggunakan kuesioner Hamzah B Uno dan data tingkat prestasi menggunakan nilai ujian blok neurologi mahasiswa semester 5 2020/2021 FK UMS. Data dianalisis menggunakan uji chi square. Tingkat kecemasan mempunyai nilai p= 0,003 dan nilai OR= 17,024. Motivasi belajar mempunyai nilai p= 0,001 dan nilai OR= 24,187. Terdapat hubungan yang signifikan antara tingkat kecemasan dan motivasi belajar terhadap prestasi belajar.
The Effect of Sleep Quality on Blood Pressure: Literature Review Setiawan, Arif; Sulistyani, S; Herawati, Erna; Basuki, Sri Wahyu
Prosiding University Research Colloquium Proceeding of The 15th University Research Colloquium 2022: Mahasiswa (Student Paper Presentation) A
Publisher : Konsorsium Lembaga Penelitian dan Pengabdian kepada Masyarakat Perguruan Tinggi Muhammadiyah 'Aisyiyah (PTMA) Koordinator Wilayah Jawa Tengah - DIY

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Background : Hypertension generally affects adults to the elderly. In many countries, the diagnosis of hypertension is made at a systolic blood pressure (SBP) of at least 140 mmHg, and a diastolic blood pressure of at least 90 mmHg. Several studies have reported correlations between sleep duration and chronic conditions, including type 2 diabetes, obesity, atherosclerosis, and high blood pressure. Purpose : Knowing the effect of sleep quality on blood pressure. Method : This Research is a literature review type. Literature review data was collected by browsing published article on pubmed, science direct, and google scholar databases. Result : Search results obtained (1297) from Pubmed database, (980) articles from Google Scholar, (1001) from Science Direct articles. Most (11/12) studies show that sleep quality and sleep duration have an effect on systolic blood pressure. Conclusion : Poor sleep quality and sleep duration of less than 7 hours, especially less than 5 hours are at risk of increasing the incidence of hypertension.
Co-Authors Afifah, Siti Zulfatul Amalia, Riza Andyani, Nanda Arum Anika Candrasari Arif Setiawan Azwar, Muhammad Thoriq Burhannudin Ichsan Busyra, B Devi Usdiana Rosyidah Djatmiko, Safari Wahyu Dodik Nursanto Erika Diana Risanti Erna Herawati, Erna Futana, Ninda Pradani Goprani, Lidya Hutami, Norma Putri Iwan Setiawan kusumaningsih, dwi Nugrahaen, Sarwasri Fajra Paramadina, Izzati Pertiwi, Arum Setya Pramesti, Neva Galih Prameswari, Elza Puspitasari, Metana Puspitasari, Nadya Dwi Qotrunnajah, Annisa Rahman, Aditya Nur Rahmawati, Nailena Widya Riyana, Arlinda Silva Sri Wahyu Basuki Sulistiyo, Azka Hafiy Susanto, Syarafina Ayu Putri Tri Agustina, Tri Winarsih, Danik Sri Yusuf Alam Romadhon