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Journal : Al-Kimia

Effectiveness of Spinach Leaf Extract (Amaranthus spinosus L.) as an Anti-inflammatory against Paw Edema of White Rats (Rattus norvegicus) Aisyah, Sitti; Fauziah, Sitti
Al-Kimia Vol 12 No 2 (2024): DECEMBER
Publisher : Study Program of Chemistry - Alauddin State Islamic University of Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/al-kimia.v12i2.47776

Abstract

Spinny leaves (Amaranthus spinosus L.) are widely used in traditional medicine in the community, apart from their function as a food ingredient. Spinach leaves contain active compounds that can treat inflammation. This study investigates the effect of thorn spinach leaf extract on carrageenan-induced oedema of the legs of female white rats (Rattus norvegicus). An experimental method with a randomized block design (RAK) was employed, which consisted of five treatments and three repetitions. The study results showed that spinach leaf extract (Amaranthus spinosus L.) significantly reduced carrageenan-induced inflammation in the feet of female white rats. The anti-inflammatory effect of spinach leaf extract is practical at a dose of 1250 Mg/kg BW.