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All Journal Majalah Kesehatan FKUB Health and Medical Journal Lexeme : Journal of Linguistics and Applied Linguistics JOURNAL LA MEDIHEALTICO Jurnal Ilmiah Rehabilitasi Sosial (Rehsos) Proceeding ISETH (International Summit on Science, Technology, and Humanity) Jurnal Aplikasi IPTEK Indonesia Indonesian Basic and Experimental Health Sciences
Aulia Yasmin, Aulia
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Humanities Biochemistry, Genetics & Molecular Biology Computer Science & IT Education Engineering Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary Other

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PENGARUH KADAR GLUKOSA TERHADAP EKSPRESI PROTEIN AdhO36 BAKTERI Salmonella Typhi Winarsih, Sri; Sujuti, Hidayat; Yasmin, Aulia
Majalah Kesehatan FKUB Vol 4, No 3 (2017): MAJALAH KESEHATAN FAKULTAS KEDOKTERAN
Publisher : Faculty of Medicine Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (612.515 KB) | DOI: 10.21776/ub.majalahkesehatan.2017.004.03.1

Abstract

Demam tifoid yang disebabkan oleh Salmonella Typhi merupakan salah satu penyakit infeksi terbanyak penyebab rawat inap penderita di Indonesia. Sehingga diperlukan penelitian tentang faktor-faktor yang mempengaruhi patogenesitas dari S.Typhi salah satunya adalah kadar glukosa. S. Typhi diketahui memiliki molekul adhesin pada bagian  outer membrane protein (OMP) dengan berat molekul 36 kDa atau disebut juga AdhO36. Molekul adhesin ini berfungsi sebagai perlekatan bakteri pada sel hospes. Pada penelitian ini ingin diketahui pengaruh kadar glukosa terhadap ekspresi protein AdhO36 OMP S. Typhi. Perlakuan glukosa diberikan pada lima kelompok bakteri yaitu konsentrasi 40 mg/100mL, 80 mg/100mL, 160 mg/100mL, 240 mg/100mL dan 320 mg/100mL. Hasil elektroforesis OMP pada lima kelompok bakteri tersebut menunjukkan peningkatan ketebalan pita protein, yaitu semakin tinggi kadar glukosa akan  semakin tebal protein yang  terekspresi. Ketebalan pita protein OMP 36 kDa dibaca menggunakan program Corel Photo Paint 11. Hasil analisis statistik menunjukkan perbedaan yang tidak bermakna (ANOVA, p = 0,559), namun secara deskriptif terlihat adanya peningkatan ketebalan protein OMP 36 kDa pada perlakuan konsentrasi glukosa yang makin besar. Kesimpulan penelitian ini adalah peningkatan kadar glukosa cenderung akan meningkatkan ekspresi protein AdhO36 S. Typhi. Kata kunci : AdhO36, Kadar Glukosa, OMP, Salmonella Typhi
Sistem Pendeteksi Asap Rokok Dengan Sensor MQ-2 Berbasis Mikrokontroler ESP32 Harahap, Erwin; Dhaifullah, Haris; Badruzzaman, Farid; Suparman, Anan; Suliadi, Suliadi; Yasmin, Aulia
Jurnal Aplikasi IPTEK Indonesia Vol 6, No 1 (2022)
Publisher : Universitas Negeri Padang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24036/4.16457

Abstract

Dalam kehidupan sehari-hari seringkali ditemukan berbagai macam tipe asap di lingkungan sekitar seperti: asap rokok, asap hasil pembakaran sampah, dan asap lainnya. Asap merupakan suatu hal yang dapat membahayakan tubuh ketika terhirup, dan keberadaannya juga dapat menandakan bahwa terdapat suatu barang yang sedang terbakar. Pada paper ini penulis merancang sebuah Sistem Pendeteksi Asap Rokok (SPAR) secara real-time berbasis sensor MQ-2 dan mikrokontroler ESP32. SPAR ditempatkan pada lokasi tertentu yang dapat memonitor suatu wilayah secara keseluruhan. Sensor MQ-2 berfungsi untuk mendeteksi keberadaan asap (diantaranya asap rokok) di wilayah tersebut dalam bentuk sinyal analog. Sinyal ini kemudian diterjemahkan ke dalam kode digital dan dibaca oleh mikrokontroler ESP32. Selanjutnya ESP32 mengirimkan perintah kepada buzzer untuk memberikan respon yang sesuai dengan kode program yang telah dirancang. Buzzer akan memberi respon berupa bunyi alarm, dimana hal ini menunjukkan bahwa telah terdeteksi adanya asap rokok di sekitar wilayah tersebut. Melalui suara alarm ini, pihak yang berwenang dapat segera memberikan respon yang sesuai. Hasil penelitian dan eksperimen telah berhasil membuat alat SPAR dan berfungsi baik dalam mendeteksi asap rokok.
Profile of Shingles Patients in Outpatient Settings Dermatology and Venereology Noviani, Laura; Kariosentono, Harijono; Yasmin, Aulia; Kusumasari, Nila
Journal La Medihealtico Vol. 5 No. 4 (2024): Journal La Medihealtico
Publisher : Newinera Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37899/journallamedihealtico.v5i4.1498

Abstract

Herpes zoster (HZ) is a latent varicella zoster virus (VZV) reactivation has been related to aging and immunocompromised condition that affects the skin and mucosa. It becomes increasingly common. However, studies on the clinical profile of HZ in Indonesia are still lacking. Objective of the study is to describe clinico-epidemiological profiles of HZ in Dr. Moewardi General Hospital Surakarta, Indonesia in the period of January 2018 – December 2022. We conducted a retrospective study using the medical records of patients visiting Dermatovenereology Outpatient Clinic of Dr. Moewardi General Hospital Surakarta from January 2018 to December 2022. 48 subjects included in this study 31 of them are females (65%). The subjects were dominated by those aged >50 years old (n:30; 63%). Herpes zoster mostly occurred at thoracal dermatome (n:22: 46%). Top three comorbidities were hypertension (n:10; 21%) followed by autoimmune diseases (n:9: 18%) and malignancy history (n; 6; 13%). Antiviral drugs (n:33; 69%) and antibiotic ointment (n:33; 69%) were the most therapy. More than 50% of subjects received anticonvulsant gabapentin (n:28; 58%) and one-fourth of subjects received analgesic (n:12; 25%). Herpes Zoster most affects middle adulthood population invo involving thoracal dermatome. Hypertension, autoimmune disease and history of malignancy are the common comorbidity. The main therapy of HZ is antivirus in combination with anticonvulsant and analgesic.
Reduction of Interleukin-6 after PRP-Exosomes Treatment in A Mouse Model of Androgenetic Alopecia Ellistasari, Endra Yustin; Widhiati, Suci; Julianto, Indah; Rosmarwati, Ervina; Monica, Pristia Widya; Yasmin, Aulia
Proceeding ISETH (International Summit on Science, Technology, and Humanity) 2024: Proceeding ISETH (International Summit on Science, Technology, and Humanity)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/iseth.5508

Abstract

Purpose: This study aim to determine the role of platelet-rich plasma (PRP) exosomes as anti-inflammatory (IL-6) in a mouse model of androgenetic alopecia. Methodology: There are four group of androgenetic alopecia mice model with no treatment group (control group, K1), group treated with PRP-exosomes (K2), group treated with 5% topical minoxidil (K3) and the last group treated with combination of PRP-exosomes and 5% topical minoxidil (K4). All of the group was evaluated clinically and immunohistochemical examination of IL-6 was performed on the 32nd day. Results: Better hair growth results were obtained in the treatment group compared to the control group. In clinical evaluation, K4 had the best results, followed by K2 and K3. The expression of IL-6 is highest in the K1, followed by K4, K2 and K3 and statistically significant. Applications/Originality/Value: PRP-exosomes can enhance hair growth in androgenetic alopecia mice model. IL-6 expression in the control group is significantly higher than in the treatment group.
IMPLEMENTASI THERAPEUTIC COMMUNITY (TC) PADA PROGRAM REHABILITASI SOSIAL PENYALAHGUNAAN NARKOBA DI BALAI BESAR REHABILITASI BADAN NARKOTIKA NASIONAL LIDO KABUPATEN BOGOR Yasmin, Aulia; Supiadi, Epi; Deswanti, Arini Dwi
Jurnal Ilmiah Rehabilitasi Sosial (Rehsos) Vol 7 No 2 (2025): REHSOS (In Press)
Publisher : Politeknik Kesejahteraan Sosial (Poltekesos) Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31595/rehsos.v7i2.1707

Abstract

This study examines the implementation of the Therapeutic Community method (TC) in the Social Rehabilitation Program for drug abusers at the National Narcotics Agency (BNN) Lido, Bogor Regency. TC prioritizes support from a positive social environment to provide positive mutual support and restore their social functioning. This study is a descriptive qualitative study. Informants in this study used a purposive sampling technique with a total of 7 informants consisting of 2 rehabilitation clients, 1 counselor, 1 nurse, 1 inpatient officer, 1 psychologist, and 1 vocational trainer at BNN Lido. The results of the study indicate that the implementation of the TC method is carried out through three stages: induction, adaptation, and facilitation. The induction stage is the stage that focuses on helping new clients become community members and involving clients in the social rehabilitation program at the rehabilitation institution. In the adaptation stage, basic life skills therapy services or vocational training are provided to develop self-abilities and work skills for clients. The facilitation stage is the development of a positive social support network. The main activities in the facilitation stage are client independence and the application of skills acquired during rehabilitation. Based on research results, the implementation of the TC method in the social rehabilitation program for drug abuse at the National Narcotics Agency (BNN) in Lido has been running according to procedure, but there is still a risk of relapse among clients after rehabilitation due to triggers from their home environment, social pressure, and lingering societal stigma. Keywords: social rehabilitation, therapeutic community, drug abuse  
Unveiling Hidden Meanings: Implicature in Donald Trump’s 2017 UN General Assembly Address Hsb, Nur Reski Amelia Pepin; Yasmin, Aulia; Khasanov, UsmonAli
Lexeme : Journal of Linguistics and Applied Linguistics Vol. 8 No. 1 (2026): JANUARY 2026
Publisher : Universitas Pamulang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32493/ljlal.v8i1.55806

Abstract

Political discourse frequently employs implied meanings to convey ideological positions, authority, and persuasion in indirect ways. This study investigates the use of implicature in Donald Trump’s 2017 United Nations General Assembly Address, with a specific focus on identifying the types of implicature and explaining their pragmatic functions within a global diplomatic context. The research aims to reveal how implied meanings operate as strategic rhetorical tools in political communication. Using a descriptive qualitative approach, fifteen selected utterances from the speech were analyzed based on Grice’s (1975) theory of implicature, which categorizes implicature into Particularized Conversational Implicature, Generalized Conversational Implicature, and Conventional Implicature. The analysis reveals that Particularized Conversational Implicature is the most dominant type found in the speech, followed by Generalized Conversational Implicature and Conventional Implicature. This dominance indicates that the speaker heavily relied on contextual factors, shared political knowledge, and audience assumptions to convey criticism, warnings, and ideological stances implicitly rather than explicitly. The use of context- dependent implicature allows sensitive political messages, including threats and evaluations of other nations, to be communicated indirectly while maintaining diplomatic formality. These findings suggest that implicature plays a crucial role in shaping meaning, managing face, and influencing audience interpretation in international political discourse. This study contributes to the field of pragmatics and political discourse analysis by demonstrating how implicature functions as a strategic linguistic resource in high-level diplomatic speeches and by highlighting the importance of pragmatic interpretation in understanding political communication beyond literal meaning.
The Effectiveness of Topical Insulin for Ulcer Healing: A Pilot Study: A Pilot Study Nareswari, Adniana; Rosmarwati, Ervina; Wijayawati, Merlina; Oktiningrum, Hastika Dwi; Yasmin, Aulia
Indonesian Basic and Experimental Health Sciences Vol. 14 No. 2 (2026): April
Publisher : Rumah Sakit Umum Daerah Dr. Moewardi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/ibehs.vol14iss2pp123-127

Abstract

Introduction Chronic ulcers continue to pose a major clinical challenge, contributing to significant morbidity and mortality. These conditions are frequently associated with diabetes, venous disorders, neuropathy, and other systemic illnesses. Conventional treatments often yield suboptimal results, encouraging investigation into alternative approaches such as topical insulin. This study aims to evaluate the effectiveness and safety of topical insulin in promoting ulcer healing. Method A pre-post interventional pilot study was conducted at Dr. Moewardi General Hospital from September to October 2024. Seven patients aged 40-80 years with grade II-III ulcers were treated with a topical insulin solution (10 IU insulin in 1 mL saline), applied once daily for 14 days. Ulcer size was measured on days 0, 7, and 14. Adverse effects were also monitored. Result Out of seven participants, three showed significant improvement in ulcer size (75-100% reduction), three showed mild to moderate improvement (8-26%), and one had no response. No local or systemic adverse events, including hypoglycemia, were observed. Factors such as limited patient mobility affected follow-up adherence. Discussion The findings suggest topical insulin enhances ulcer healing through mechanisms involving cell proliferation, angiogenesis, and anti-inflammatory effects, consistent with prior studies. However, the small sample size and loss to follow-up limit generalizability. Further trials are required to confirm its clinical utility. Conclusion Topical insulin appears to be a safe and potentially effective adjunct therapy for ulcer healing in both diabetic and non-diabetic patients. Larger-scale studies with control comparisons are needed to confirm its efficacy and optimize treatment protocols.
Demographic Characteristics and Treatment Patterns of Tinea Corporis at a Tertiary Referral Hospital in Surakarta, Indonesia Kusumasari, Nila; Mulianto , Nurrachmat; Laili, Utiya Nur; Marifah, Firdausul; Yasmin, Aulia; Noviani, Laura
Health and Medical Journal Vol. 8 No. 2 (2026): May 2026
Publisher : Universitas Baiturrahmah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33854/heme.v8i2.2252

Abstract

Latar Belakang: Tinea corporis merupakan infeksi jamur superfisial yang umum disebabkan oleh dermatophytes yang menginfeksi kulit. Prevalensi tinea corporis tinggi di negara tropis seperti Indonesia. Namun, data epidemiologi lokal masih terbatas. Tujuan: Penelitian ini bertujuan untuk mendeskripsikan karakteristik klinis dan demografis pasien dengan tinea corporis yang berobat ke Poliklinik Dermatologi dan Venereologi di Rumah Sakit Umum Dr. Moewardi, Surakarta, antara Januari 2020 dan Desember 2024. Metode: Penelitian ini merupakan studi analitik retrospektif yang memanfaatkan data sekunder dari rekam medis pasien tinea corporis yang berobat di Poliklinik Rawat Jalan Dermatologi dan Venereologi RSUD Dr. Moewardi selama periode penelitian. Hasil: Penelitian ini melibatkan 167 pasien dengan diagnosis tinea corporis. Mayoritas pasien berjenis kelamin perempuan (57,5%) dan berada pada kelompok usia dewasa (64,7%). Sebagian besar pasien memiliki tingkat pendidikan menengah (55,7%) serta pekerjaan sebagai ibu rumah tangga (18%) dan karyawan sektor swasta (18%). Berdasarkan Body Mass Index (BMI), 50,3% pasien memiliki berat badan normal. Sebanyak 24,5% termasuk overweight dan 12,6% obesitas. Komorbiditas ditemukan pada 59,9% pasien. Terapi yang paling sering diresepkan meliputi antijamur topikal (87,4%). Terapi adjuvan diberikan pada 83,8% pasien. Antijamur sistemik diberikan pada 58,7% pasien. Kesimpulan: Sebagian besar pasien tinea corporis di Poliklinik Dermatologi dan Venereologi RSUD Dr. Moewardi merupakan perempuan dewasa dengan status gizi normal dan tingkat pendidikan menengah. Tatalaksana yang paling sering digunakan adalah antijamur topikal. Terapi tambahan diberikan pada pasien dengan komorbiditas. Antijamur sistemik digunakan pada proporsi pasien yang bermakna dengan temuan komorbiditas.
Co-Authors A.A. Ketut Agung Cahyawan W Badruzzaman, Farid Deswanti, Arini Dwi Dhaifullah, Haris Ellistasari, Endra Yustin Epi Supiadi Erwin Harahap Hidayat Sujuti Hsb, Nur Reski Amelia Pepin Indah Julianto, Indah Kariosentono, Harijono Khasanov, UsmonAli Laili, Utiya Nur Marifah, Firdausul Monica, Pristia Widya Mulianto , Nurrachmat Nareswari, Adniana Nila Kusumasari Noviani, Laura Oktiningrum, Hastika Dwi Rosmarwati, Ervina Suliadi Suliadi Suparman, Anan Widhiati, Suci Wijayawati, Merlina