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All Journal Jurnal Biosains Pascasarjana Jurnal Pengabdian UNDIKMA
Zuhri, Fuad Minan
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Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Library & Information Science Mathematics Nursing Public Health Social Sciences Other

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Mitigasi Sejak Dini Hipertensi pada Penyintas Bencana Tanah Bergerak Desa Mendala Kabupaten Brebes Zuhri, Fuad Minan; Indarwati, Uli Mas’uliyah; Sulistiyowati, Retno; Mujahid, Ikhsan; Fajri, Ahmad
Jurnal Pengabdian UNDIKMA Vol. 6 No. 3 (2025): August
Publisher : LPPM Universitas Pendidikan Mandalika (UNDIKMA)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33394/jpu.v6i3.16939

Abstract

This community service activity aims to enhance knowledge and awareness of disaster-related hypertension and its associated health risks, while simultaneously facilitating early detection of elevated blood pressure among survivors residing in Mendala Village Brebes Regency. The activity involved health counseling, health checks, and free medication for 140 survivors. This activity was carried out through three stages: planning, implementation, and evaluation. The results of blood pressure checks were 50 people who experienced hypertension 1, 2 and systolic, with risk factors mostly middle-aged, elderly and old age as much as 75.6%, and 35.2% were active smokers from men. The evaluation showed a high level of participation and enthusiasm in participating in this activity, where survivors received education related to disaster hypertension, screening, health consultation and free medicine.
THE RELATIONSHIP OF HEAT SHOCK PROTEINS TO TUBERCULOSIS INFECTION: A SYSTEMATIC REVIEW Muim, Rosyinta; Marviella, Sephia Tiara; Zuhri, Fuad Minan
Jurnal Biosains Pascasarjana Vol. 27 No. 2 (2025): JURNAL BIOSAINS PASCASARJANA
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jbp.v27i2.2025.91-104

Abstract

ABSTRAK Tuberculosis infection is a global health problem that occurs in almost every part of the world. HSPs are expressed by MTB when stimulated by stress in response to physiological pressure. We used PubMed, MDPI, and Scopus database to select eligible studied for systematic review published between January 1, 2019 and March 02, 2024. We investigated potential publication bias by examining quality assessment using the SCIRAP tool. From the articles reviewed, it was found that HSPs can play a role in TB infection both as therapeutic agents, biomarkers, and as new diagnostic agents to support the control of TB infection which is still an endemic infection. Types of HSPs that are known to play a role in TB infection are: HSPX, HSP16.3, HSP70, HSP27, and HSPR. This research concluded that HSPs are expressed by MTB under stress, and the expressed HSPs are then used as biomarker for effective diagnostic testing of TB infection, especially latent TB infection, as well as their development as therapeutic agent for making drugs for TB infection.
POTENTIAL OF SACHA INCHI (Plukenetia volubilis L.) AS AN ANTICANCER : A SYSTEMATIC REVIEW Fadhilah, Nadiah Farah; Nastiti, Chyntia Tresna; Zuhri, Fuad Minan
Jurnal Biosains Pascasarjana Vol. 27 No. 2 (2025): JURNAL BIOSAINS PASCASARJANA
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jbp.v27i2.2025.105-118

Abstract

Cancer is the leading cause of death worldwide. WHO estimated 20 million new cancer cases and 9.7 million deaths in 2022. The increasing incidence of cancer encourages development of new therapeutic agents for higher patient survival rate. Plant products are widely studied, one of which is Sacha Inchi (Plukenetia volubilis L.) extract. Sacha Inchi is known to have contents with anticancer potential, but information regarding its effectiveness is still limited. This systematic review aims to provide in-depth review on studies focus on anticancer potential of Sacha Inchi. The searching process was conducted in 4 databases such as National Library of Medicine (MEDLINE-PubMed), Scopus, Springerlink, and Sciencedirect. Keywords used were combination of "sacha inchi”, "plukenetia volubilis”, "anticancer”, "antineoplastic”, "antiproliferative”. Studies selection and data extraction obtained 17 studies provided information on extracts of Sacha Inchi plants and their anticancer-potential contents, both in vitro and in vivo. Polyunsaturated fatty acids and phenolic compounds were the most identified compounds. Other identified substances were tocopherols, peroxides, amino acids, steroids, terpenoids, flavonoids, proteins. Included studies showed antioxidant and anticancer potential of Sacha inchi.
Co-Authors Ahmad Fajri Fadhilah, Nadiah Farah Ikhsan Mujahid Indarwati, Uli Mas’uliyah Marviella, Sephia Tiara Muim, Rosyinta Nastiti, Chyntia Tresna Retno Sulistiyowati