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All Journal Sainteks MEDISAINS Proceeding Seminar LPPM UMP Tahun 2014 BIO-SITE |BIOLOGI Sains Terapan Jurnal Keperawatan Muhammadiyah Jurnal Analis Medika Biosains (JAMBS) Medical Technology and Public Health Journal Jurnal Kesehatan Jurnal Pengabdian UNDIKMA International Islamic Medical Journal Proceedings Series on Health & Medical Sciences Proceedings Series on Social Sciences & Humanities Proceedings Series on Physical & Formal Sciences Journal of Medical Laboratory Research
Ikhsan Mujahid
Universitas Muhammadiyah Purwokerto
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Uji Proliverasi dan Uji Apotoksis Ganoderma lucidum (Curtis) P. Karst sebagai Antikanker Serviks Mujahid, Ikhsan; Muchtasjar, Bunyamin
Proceeding Seminar LPPM UMP Tahun 2014 2014: Proceeding Seminar Hasil Penelitian LPPM 2014, 6 September 2014
Publisher : Proceeding Seminar LPPM UMP Tahun 2014

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Abstract

ABSTRAKGanoderma lucidum (Curtis) P. Karst dikenal sebagai penyakit pada pohon juga sebagai obat bagi kesehatan atau medicinal mushroom.G. lucidum menarik perhatian banyak peneliti karena senyawa yang dikandungnya memiliki aktivitas antikanker. Tujuan penelitian untuk mengkaji antiproliferasi dan induksi apoptosis dari tiga jenis ekstrak miselium G. lucidum  serta membandingkan pengaruh antiproliferasi dan induksi apoptosis dari ketiga jenis ekstrak tersebut terhadap kanker serviks secara in vitro.  Penelitian dilakukan secara eksperimental, dengan perlakuan ekstrak etanol, etil asetat dan n-heksan miselium GL2 dengan konsentrasi masing-masing ekstrak uji 1000 µg/ml, 500 µg/ml, 250 µg/ml, 125 µg/ml, dan 62,5 µg/ml, serta kontrol. Pengesktraksian miselium GL2 dengan metode maserasi. Aktivitas antikanker dilakukan dengan uji antiproliferasi dan induksi apoptosis sel HeLa. Hasil penelitian menunjukan bahwa ekstrak etanol, etil asetat dan n-heksan miselium GL2 memiliki potensi sebagai antikanker serviks diperlihatkan dengan sifat sitotoksiknya terhadap sel HeLa dengan nilai IC50 di bawah 1000 µg/ml. Nilai IC50 ekstrak etanol 158,202 µg/ml, ekstrak etil asetat 114,270 µg/ml dan n-heksan 77,987 µg/ml. Berdasarkan uji doubling time ketiga ekstrak mampu menghambat proliferasi sel HeLa dan mampu menyebabkan apoptosis sel HeLa. Terdapat perbedaan kesitotoksikan dari ketiga ekstrak miselium GL2, paling kuat kesitotoksikannya adalah ekstrak n-heksan. Tidak terdapat perbedaan waktu doubling time atau waktu pembelahan sel HeLa dari ketiga ekstrak pada konsentrasi di bawah 200 µg/ml dan mampu menghambat pembelahan sel kanker serviks melalui mekanisme apoptosis. Kata  Kunci : G. lucidum, antikanker, serviks
PETA DEMOGRAFI MASYARAKAT DAERAH ENDEMIS DEMAM BERDARAH DENGUE (DBD) Hikmawati, Isna; Mujahid, Ikhsan
Proceeding Seminar LPPM UMP 2015: Buku III Bidang Ilmu Kesehatan dan Sains Teknik, Proceeding Seminar Nasional LPPM 2015, 26 Se
Publisher : Proceeding Seminar LPPM UMP

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Abstract

Kurangnya gambaran masyarakat di daerah endemis DBD seringkali membuat upaya-upaya program pemberantasan demam berdarah menjadi tidak efektif. Tujuan penelitian membuat peta demografi masyarakat untuk langkah awal identifikasi kebutuhan masyarakat dalam pengendalian demam berdarah. Metode Penelitian deskriptif untuk menggambarkan karakteristik  demografi masyarakat. Hasil penelitian Peta karakteristik demografi masyarakat untuk status pekerjaan sebagian besar ibu rumah tangga, umur antara 41-50,  pendidikan sekolah dasar, dan kasus kejadian DBD terbanyak ada di RW 3. Peta kondisi tempat tinggal  masyarakat  seimbang antara lingkungan sanitasi baik dan kurang. Peta praktek pencegahan demam  berdarah  pada masyarakat masih kurang baikKata Kunci : Masyarakat Endemis, DBD
Efektifitas Jus Semangka Dan Jus Pepaya Terhadap Penurunan Tekanan Darah Penderita Hipertensi Di Puskesmas Kembaran 1 Banyumas Cahyani, Tri Oka Regita; Mujahid, Ikhsan
Jurnal Keperawatan Muhammadiyah Vol 5, No 2 (2020): JURNAL KEPERAWATAN MUHAMMADIYAH
Publisher : UNIVERSITAS MUHAMMADIYAH SURABAYA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jkm.v5i2.4710

Abstract

Objective:  To determine the effectiveness of watermelon juice and papaya juice on blood pressure in patients with hypertension at the Puskesmas (Public Health Care Center) Kembaran I Banyumas.Methods: This research uses quantitative methods with a quasi-experimental design with a pre-post group. The sample selection using a purposive sampling technique obtained 15 respondents in the watermelon juice group and 15 respondents in the papaya juice group. The statistical tests used are Paired t-test and independent t-testResults: The results of the study found that the average systolic blood pressure of the watermelon juice group was from 148.13 in the beginning to 138.93. The average diastolic blood pressure was 85.80 to 80.60. While the average systolic blood pressure of the papaya juice group was from 149.40 in the beginning to 145.67, the average diastolic blood pressure was from 84.20 to 80.80. There were significant differences in systolic and diastolic blood pressure before and after treatment in the watermelon juice and papaya juice groups with p0.05. There is a significant difference in the effectiveness of watermelon juice and papaya juice on the reduction of systolic and diastolic blood pressure with p0.05.Conclusion: Watermelon juice is more effective than papaya juice for reducing blood pressure in patients with hypertension at the Puskesmas Kembaran 1 Banyumas.
Kemampuan Air Kelapa Muda Sebagai Antimikroba Terhadap Bakteri Escherichia coli Penyebab Diare Arif Mulyanto; Ikhsan Mujahid; Tyas Ulfah Khasanah
BIO-SITE |Biologi dan Sains Terapan Vol. 4 No. 1 (2018): Bio-Site
Publisher : Biology Department, Faculty of Science and Technology, Univeristas Jambi, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (314.072 KB) | DOI: 10.22437/bs.v4i1.4963

Abstract

Diarrhea is a circumstance when the body loses much fluid and electrolyte through feces. According to the data obtained by Ministry of Health of the Republic of Indonesia (2016), in 2015 there were 18 cases of healthemergency of diarrhea, spread over 11 provinces and 18 regencies/cities. There were 1.213 people who got the disease, 30 of them died. Partially, villagers treated diarrhea by drinking young coconut water. This research aimsto discover the effectiveness of several kinds of young coconut water as antimicrobials to bacteria that can causediarrhea (bacteria test) such as Escherichia coli. In this research the inhibitionof young coconut water sample toward above-mentioned bacteria was held. Besides, a phytochemical screeningtest was also conducted to find out the antimicrobial substances contained in young coconut water. The data of young coconut water antimicrobial testing toward Escherichia coli, wereanalyzed by employing analysis of varian (ANOVA) with F test on 95% confidence level. Data testing wasfollowed by Duncan test on 95% confidence level. Research results indicated that young coconut water had antimicrobial ability toward Escherichia coli. Based on the result ofphytochemical screening of the young coconut water (all treatments) it was only secondary metabolite tannins detected. All treatments (of the young coconut water) could inhibit tested bacteria. It is allegedly because thewater contained tannins. The water of green coconut (used as a traditional medicine) was an effective inhibitor of bacteria growth bacteri. On E. coli the inhibition zone diameter was 11,6 mm. Keywords: young coconut water, antimicrobial, bacteria, diarrhea
Pemberian Senam Ergonomik Berbasis Spiritual pada Lansia dengan Prediksi Arthritis Gout di wilayah kerja Puskesmas Sokaraja I Triana Ayu Anggraeni; Ikhsan Mujahid
Jurnal Keperawatan Muhammadiyah 2020: JKM EDISI KHUSUS SEPTEMBER 2020
Publisher : UNIVERSITAS MUHAMMADIYAH SURABAYA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jkm.v0i0.5322

Abstract

ABSTRACT Background: Gout which is commonly known as athritis gout is a disease caused by the accumulation of monosodium uric crystals in the body. Athritis gout is a degenerative disease that attacks the joints and is often experienced by the elderly. Athritis gout can be intervened with non-pharmacological therapy, one of which is ergonomic gym. Ergonomic gym is a muscle movement that is combined with breathing techniques.Objective: To figure out the influence of giving spiritual-based ergonomic gym to the elderly with prediction of arthritis gout in the working area of Public Health Care Center of Sokaraja I.Method: A quantitative method was used in this study. The quasi- experimental pre-test and post-test nonequivalent control group design was used as research design. The samples were elderly people aged 45-59 years in Integrated Health Service Post (Posyandu) Karangnanas in the working area of Public Health Care Center of Sokaraja I. There were 42 respondents which were collected by using the consecutive sampling method in December 2019. The research instruments were in the form of respondent demographic data, pre-posttest observation sheets and a tool to check uric acid levels.Results: The average difference in measurement of uric acid levels (pre-posttest) in the treatment group was 0.5619, while in the control group, it was 0.3000. T-Test Independent results on the difference in the pre-posttest results of the treatment group and the control group obtained p-value of 0.002 or p <0.05. It meant that there were significant differences in the decrease of uric acid levels between the treatment group and the control group.Conclusion: There is a difference in the decrease of uric acid levels in the treatment group and the control group. The result shows the influence of giving spiritual-based ergonomic gym for decreasing uric acid levels in the elderly with arthritis gout prediction.Keywords: Arthritis Gout, elderly, spiritual based ergonomic gym
The effect of giving boiled water of sirsake on the reduction of uric acid Riyo Fajar Iman; Ikhsan Mujahid
Proceedings Series on Health & Medical Sciences Vol. 1 (2020): Proceedings of the 1st International Conference of Health Science Faculty Universitas
Publisher : UM Purwokerto Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (361.869 KB) | DOI: 10.30595/pshms.v1i.40

Abstract

Kajian Potensi Pengembangan Agrowisata di Desa Sambirata, Kecamatan Cilongok, Kabupaten Banyumas Suwarsito Suwarsito; Aman Suyadi; Astika Nurul Hidayah; Ikhsan Mujahid
Proceedings Series on Physical & Formal Sciences Vol. 4 (2022): Prosiding Seminar Nasional Fakultas Pertanian dan Perikanan
Publisher : UM Purwokerto Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/pspfs.v4i.530

Abstract

Tujuan penelitian ini adalah untuk mengkaji potensi pengembangan agrowisata di Desa Sambirata, Kecamatan Cilongok, Kabupaten Banyumas. Penelitian ini menggunakan metode observasi dengan pendekatan deskriptif kualitatif. Metode observasi digunakan untuk mengamati potensi agrowisata di Desa Sambirata, Kecamatan Cilongok, Kabupaten Banyumas. Metode deskriptif kualitatif digunakan untuk menjelaskan potensi internal dan eksternal agrowisata di Desa Sambirata. Data penelitian berupa data primer yang diperoleh langsung dari pengamatan di lapangan, meliputi data potensi internal dan eksternal agrowisata di Desa Sambirata. Teknik pengumpulan data penelitian menggunakan metode observasi dan studi pustaka Analisis data menggunakan matching data untuk menilai potensi internal dan eksternal agrowisata berdasarkan Rencana Induk Pembangunan Pariwisata Daerah (RIPPDA). Potensi internal meliputi data daya tarik wisata (attraction) dan fasilitas wisata (amenities), sedangkan potensi eksternal meliputi aksesibilitas wisata (accesability) dan pelayanan tambahan (ancilliary). Selanjutnya dari hasil matching data dikategorikan menjadi tiga kriteria yaitu rendah, sedang dan tinggi. Berdasarkan hasil penelitian menunjukkan bahwa potensi agrowisata di Desa Sambirata, Kecamatan Cilongok, Kabupaten Banyumas secara keseluruhan termasuk dalam kategori rendah. Faktor-faktor yang menyebabkan rendahnya potensi agrowisata Desa Sambirata adalah fasilitas wisata (amenities), aksesibilitas (accesability) dan pelayanan penunjang wisata (ancillary).
Hubungan Perilaku Masyarakat dengan Kepatuhan Protokol Kesehatan Masa Pandemi Covid-19 di Purwanegara Purwokerto Tety Dwi Prasetyoningsi; Ikhsan Mujahid
Proceedings Series on Health & Medical Sciences Vol. 4 (2023): Proceedings of the Midwifery Conference on Collaborative Maternity Care (DYNAMIC)
Publisher : UM Purwokerto Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/pshms.v4i.564

Abstract

Dalam memutus rantai penyebaran virus covid-19. Masyarakat merupakan faktor penting tercapainya tujuan sehingga dibutuhkan upaya yang lebih untuk meningkatkan kesadaran dan kepatuhan masyarakat untuk meminimalisir peningkatan angka kejadian covid-19 yang meningkat setiap harinya akibat perilaku ketidakpatuhan masyarakat. Mengetahui hubungan perilaku masyarakat dengan kepatuhan protokol kesehatan masa pandemi covid-19 di Purwanegara Purwokerto. Penelitian ini adalah jenis penelitian kuantitatif yang menggunakan teknik pendekatan cross sectional dan bersifat deskriptif korelatif.Responden penelitian ini adalah masyarakat Purwanegara Purwokerto. Teknik pengampilan sampel menggunakan teknik Simple Random Sampling / acar sederhana dengan jumlah sampel 98. Karakteristik responden di Purwanegara Purwokerto memiliki rata–rata usia 15-29 tahun dengan jenis kelamin 55,1% perempuan. Sebagaian besar adalah pekerja 60,2%. Pendidikan terakhir sekolah menengah atas 42,9%. Status kesehatan sehat 96,9%. Perilaku masyarakat dalam kategori kurang baik 74 (75,5%) responden dan kepatuhan masyarakat dalam kategori tidak patuh 69 (70,4%) responden. Ada hubungan yang signifikan antara perilaku masyarakat dengan kepatuhan protokol kesehatan masa pandemi covid-19 dengan nilai p value 0,000 pada signifikan 5% atau 0,050. Ada hubungan yang signifikan antara perilaku masyarakat dengan kepatuhan protokol kesehatan masa pandemi covid-19.
Antimicrobial Activity of Excoecaria Agallocha Mangrove Extract in Inhibiting the Growth of Aeromonas Hydrophila by in-Vitro Dini Siswani Mulia; Berlian Bun’ya Rista; Aman Suyadi; Ikhsan Mujahid; Cahyono Purbomartono
Proceedings Series on Social Sciences & Humanities Vol. 8 (2023): Proceeding International Seminar 2022 E-Learning Implementation in Malaysia and Indon
Publisher : UM Purwokerto Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/pssh.v8i.602

Abstract

One of the bacterial diseases that often attack freshwater fish is the red-sore disease, also known as aeromoniasis or Motile Aeromonas Septicemia (MAS). It is caused by bacteria from Aeromonas genus, such as Aeromonas hydrophila. A safe alternative treatment for pathogenic bacteria is the use of antibacterial compounds made from natural ingredients. The Excoecaria agallocha mangrove extract is one of potential alternatives that is useful as natural antimicrobials due to its various contents of antibacterial bioactive compounds. The objective of this study was to determine the antimicrobial activity of E. agallocha mangrove extract in inhibiting the growth of A. hydrophila. The research method was experimental with complete randomized design and factorial pattern of 3 factors (type of plant organ, bacterial strain, and concentration of extract), in 48 treatments and 3 replications. The solvents used consisted of methanol (polar) and n-hexane (non-polar). The plant organs used included leaves and stems. The bacterial strains consisted of GPl-04, GB-01, GL-01, GL-02, GJ-01, and GK-01 with concentrations of leaves and stems extracts of 0, 10, 20, and 30%. The parameter measured was the diameter of inhibition zone, which was done by using disc paper (Kirby Bauer method). Non-parametric Kruskall-Wallis Test and qualitative-descriptive data analysis were applied. The methanol extract of E. agallocha leaves in GJ-01 strain at 10 and 20% concentrations had antimicrobial activity with inhibition zone in 2.55 mm and 2.46 mm, respectively. The n-hexane extract of E. agallocha stem at 20 and 30% concentrations had antimicrobial activity with inhibition zones of 1.88 mm in GPl-04 strain and 1.58 mm in GB-01 strain, respectively. Extract of E. agallocha mangrove exhibited potential as a natural antibacterial to prevent aeromoniasis in fish.
Strategi Pengembangan Agrowisata Berbasis Masyarakat di Desa Sambirata, Kecamatan Cilongok, Kabupaten Banyumas Suwarsito Suwarsito; Aman Suyadi; Astika Nurul Hidayah; Ikhsan Mujahid
Sainteks Vol 19, No 2 (2022): Oktober
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat (LPPM)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/sainteks.v19i2.15171

Abstract

Agrowisata berbasis masyarakat merupakan program wisata yang memanfaatkan potensi alam dan budaya, serta dukungan masyarakat lokal dalam menjalankan program-program kegiatan wisata. Agrowisata menjadi salah satu alternatif pariwisata berkelanjutan yang bertujuan memperluas pengetahuan, pengalaman, rekreasi dan hubungan usaha di bidang pertanian. Tujuan penelitian ini adalah untuk menentukan strategi pengembangan agrowisata berbasis masyarakat di Desa Sambirata, Kecamatan Cilongok, Kabupaten Banyumas. Penelitian ini menggunakan metode pendekatan deskriptif kualitatif. Populasi penelitian adalah perangkat desa, kelompok sadar wisata (Pokdarwis), dan masyarakat Desa Sambirata. Pengambilan sampel dilakukan secara purposive sampling. Data penelitian meliputi data potensi agrowisata dan faktor-faktor pendukung dan penghambat dalam pengembangan agrowisata di Desa Sambirata. Pengumpulan data penelitian menggunakan metode observasi dan Focus Group Discussion (FGD). Data hasil observasi dan FGD dianalisis secara deskriptif kualitatif untuk menjelaskan potensi agrowisata dan faktor-faktor pendukung dan penghambat dalam pengembangan agrowisata di Desa Sambirata. Selanjutnya data hasil penelitian dianalisis SWOT (Strengths, Weaknesses, Opportunities, and Threats). Hasil analisis SWOT digunakan untuk memberikan rekomendasi dalam menentukan strategi pengembangan agrowisata berbasis masyarakat di Desa Sambirata. Berdasarkan hasil penelitian disimpulkan bahwa strategi pengembangan agrowisata berbasis masyarakat di Desa Sambirata Kecamatan Cilongok Kabupaten Banyumas, adalah 1) menyelenggarakan penyuluhan dan pelatihan dasar mengenai pengelolaan dan pengembangan agrowisata; 2) mengembangkan potensi lahan pertanian dan hutan menjadi zona agrowisata; 3) mengembangkan jaringan kerjasama kemitraan dengan pelaku industri pariwisata dan lembaga/dinas terkait untuk mempromosikan dan mengembangkan destinasi agrowisata; 4) mengembangkan website dan media promosi agrowisata berbasis masyarakat; dan 5) meningkatkan partisipasi aktif masyarakat dalam pengembangan inovasi produk agrowisata.
Co-Authors . Suwarsito Ahmad Fajri Almanfaluthi, Muhammad Lutfhi ALMANFALUTHI, MUHAMMAD LUTHFI Aman Suyadi Arif Mulyanto Arif Mulyanto, Arif Astika Nurul Hidayah Berlian Bun’ya Rista Bunyamin Muchtasjar, Bunyamin Cahyani, Tri Oka Regita Cahyono Purbomartono Chaeni, Annisa Nur Dini Siswani Mulia EKANIASARI, MEVIANA DEA Fuad Minan Zuhri Handayani, Lutfiana Isna Hikmawati Jamilah Jamilah JANG JAYA, NABELA PUTRI Khasanah, Tyas Ulfah Prabowo, Finda Rizky Putri Pristiyani, Kurnia Putri, Ayuni - Ragil Setiyabudi, Ragil Retno Sulistiyowati Riyo Fajar Iman Romadhon, Zakiyatudin Anduko Tety Dwi Prasetyoningsi Triana Ayu Anggraeni Tyas Ulfah Khasanah Uli Mas’uliyah Indarwati Wardani, Dita Pratiwi Kusuma Widodo, Oei Stefani Yuanita