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All Journal Indonesian Journal of Chemistry Jurnal Pengabdian Masyarakat Bangsa
Fajriyah, Bunga Sita Roihanul
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Toxicity Test of Nanoemulsions of Nutmeg Fruits and Leaves Essential Oil against Artemia salina Leach and Its Cytotoxicity Test against Breast Cancer Cells T47D Rastuti, Undri; Diastuti, Hartiwi; Widyaningsih, Senny; Chasani, Moch; Sheiliyani, Cindi; Rahmasari, Anisa; Fajriyah, Bunga Sita Roihanul; Mesayu, Puspa Rahma; Habibie, Ranti Kamila
Indonesian Journal of Chemistry Vol 24, No 5 (2024)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijc.91077

Abstract

Nutmeg (Myristica fragrans Houtt) is a widely known spice plant, which has been reported to offer several benefits. Therefore, this study aims to develop and analyze nanoemulsions of nutmeg leaves and fruit essential oil, as well as determine their toxicity and cytotoxicity. Nanoemulsions were formulated with varying concentrations of essential oil, including 0, 1, 2, 4, and 6%. Characterization included organoleptic assessment, pH measurement, type examination, viscosity testing, transmittance analysis, particle size distribution measurement, centrifugation, and freeze-thaw cycle test. Toxicity testing results using the brine shrimp lethality test (BSLT) showed that nanoemulsions were toxic except NF F4 with high toxicity. Cytotoxicity testing on T47D breast cancer cells showed moderate activity for NF F4 nanoemulsions (IC50: 34.363 ppm), while NL nanoemulsions were deemed inactive (IC50: 33576.430 ppm). In addition, the organoleptic characteristics of all nanoemulsions were stable, and most parameters met the desired standards. Based on the results, further studies exploring nanoemulsions with natural products must be carried out to determine their advantages, specifically in the development of sciences.
Pelatihan Manajemen dan Hibah Alat Huller Sebagai Upaya Meningkatkan Produktivitas dan Kapasitas Greenbean pada KUB Lulumpang Kec. Salem Kab. Brebes Rastuti, Undri; Purwanto, Purwanto; Yunanto, Ary; Sutarmin, Sutarmin; Fajriyah, Bunga Sita Roihanul; Alriski, Mochammad Fadhil Niko; Saputra, Dimas; Safitri, Fanti Indriana
Jurnal Pengabdian Masyarakat Bangsa Vol. 2 No. 10 (2024): Desember
Publisher : Amirul Bangun Bangsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59837/jpmba.v2i10.1686

Abstract

Kecamatan Salem merupakan wilayah dengan perkebunan dan produksi kopi tertinggi di Kabupaten Brebes. Kelompok usaha bersama (KUB) Lulumpang menjadi salah satu tim yang aktif mengolah kopi hasil perkebunan  kopi di kecamatan salem. Produk yang dibuat oleh KUB Lulumpang berupa kopi bubuk yang diberi nama Kopi Salem. Namun saat ini permintaan greenbean lebih diminati oleh konsumen. Proses produksi greenbean di KUB Lulumpang masih dilakukan secara manual sehingga menjadi kendala dalam pemenuhan kualitas dan kuantitas greenbean sehingga diperlukan inovasi peningkaan kualitas dan kuantitas greenbean. Tim PKM-BR Unsoed mengkaji dan menerapkan teknologi tepat guna dengan mengadakan pelatihan manajemen usaha dan strategi daya saing serta hibah alat pengubas kulit ari biji kopi kering (huller). Penerapan teknologi meningkatkan efisiensi waktu dan kapasitas produksi sebesar 90% dan meningkatkan nilai harga jual hingga 53,85%. 
Co-Authors Alriski, Mochammad Fadhil Niko ary yunanto Chasani, Moch Habibie, Ranti Kamila Hartiwi Diastuti Mesayu, Puspa Rahma Purwanto Purwanto Rahmasari, Anisa Safitri, Fanti Indriana Saputra, Dimas Senny Widyaningsih Sheiliyani, Cindi Sutarmin Sutarmin, Sutarmin Undri Rastuti